PT3226843T - Composições anticancro - Google Patents

Composições anticancro

Info

Publication number
PT3226843T
PT3226843T PT158203513T PT15820351T PT3226843T PT 3226843 T PT3226843 T PT 3226843T PT 158203513 T PT158203513 T PT 158203513T PT 15820351 T PT15820351 T PT 15820351T PT 3226843 T PT3226843 T PT 3226843T
Authority
PT
Portugal
Prior art keywords
anticancer compositions
anticancer
compositions
Prior art date
Application number
PT158203513T
Other languages
English (en)
Original Assignee
Aragon Pharmaceuticals Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=52006907&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=PT3226843(T) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Aragon Pharmaceuticals Inc filed Critical Aragon Pharmaceuticals Inc
Publication of PT3226843T publication Critical patent/PT3226843T/pt

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/2004Excipients; Inactive ingredients
    • A61K9/2022Organic macromolecular compounds
    • A61K9/205Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A61K9/2054Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4427Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
    • A61K31/4439Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. omeprazole
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/14Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/141Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers
    • A61K9/146Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers with organic macromolecular compounds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/2004Excipients; Inactive ingredients
    • A61K9/2022Organic macromolecular compounds
    • A61K9/2027Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • A61P35/04Antineoplastic agents specific for metastasis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0053Mouth and digestive tract, i.e. intraoral and peroral administration
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/14Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/141Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Physiology (AREA)
  • Nutrition Science (AREA)
  • Oncology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Processes Of Treating Macromolecular Substances (AREA)
PT158203513T 2014-12-05 2015-12-03 Composições anticancro PT3226843T (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP14196605 2014-12-05

Publications (1)

Publication Number Publication Date
PT3226843T true PT3226843T (pt) 2021-07-07

Family

ID=52006907

Family Applications (1)

Application Number Title Priority Date Filing Date
PT158203513T PT3226843T (pt) 2014-12-05 2015-12-03 Composições anticancro

Country Status (33)

Country Link
US (3) US10285948B2 (pt)
EP (2) EP3226843B1 (pt)
JP (1) JP6830892B2 (pt)
KR (1) KR102387089B1 (pt)
CN (1) CN106999432A (pt)
AR (1) AR102925A1 (pt)
AU (1) AU2015358497B2 (pt)
CA (1) CA2969675C (pt)
CL (1) CL2017001373A1 (pt)
CO (1) CO2017005574A2 (pt)
CR (1) CR20170218A (pt)
CY (1) CY1124504T1 (pt)
DK (1) DK3226843T3 (pt)
EA (1) EA201791251A1 (pt)
ES (1) ES2883187T3 (pt)
HR (1) HRP20211140T1 (pt)
HU (1) HUE054935T2 (pt)
IL (1) IL252325A0 (pt)
LT (1) LT3226843T (pt)
MA (1) MA41111B1 (pt)
MD (1) MD3226843T2 (pt)
MX (1) MX2017007206A (pt)
MY (1) MY192931A (pt)
NI (1) NI201700068A (pt)
PH (1) PH12017500979A1 (pt)
PL (1) PL3226843T3 (pt)
PT (1) PT3226843T (pt)
RS (1) RS62421B1 (pt)
SG (1) SG11201704386VA (pt)
SI (1) SI3226843T1 (pt)
TW (1) TWI709403B (pt)
UA (1) UA123538C2 (pt)
WO (1) WO2016090105A1 (pt)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NZ745682A (en) 2012-09-26 2019-09-27 Aragon Pharmaceuticals Inc Anti-androgens for the treatment of non-metastatic castrate-resistant prostate cancer
MD3226843T2 (ro) 2014-12-05 2021-10-31 Aragon Pharmaceuticals Inc Compoziții anticancer
CN111479560A (zh) 2017-10-16 2020-07-31 阿拉贡药品公司 用于治疗非转移性去势难治性前列腺癌的抗雄激素
WO2020144649A1 (en) 2019-01-10 2020-07-16 Aragon Pharmaceuticals, Inc. Pharmaceutical composition comprising enzalutamide dispersed in apple sauce
CN113711316A (zh) 2019-01-30 2021-11-26 詹森药业有限公司 基于分子亚型治疗前列腺癌的方法
CN113365623A (zh) 2019-01-30 2021-09-07 阿拉贡药品公司 用于治疗转移性去势敏感性前列腺癌的抗雄激素
WO2020239478A1 (en) 2019-05-28 2020-12-03 Pharma Mar, S.A. Trabectedin for treating sarcomas based on genomic markers
US11723898B2 (en) 2019-11-04 2023-08-15 Aragon Pharmaceuticals, Inc. Androgen receptor inhibitors for the treatment of non-metastatic castration-resistant prostate cancer in subjects with severe hepatic impairment
WO2021245285A1 (en) 2020-06-05 2021-12-09 Janssen Pharmaceutica Nv Methods of treating prostate cancer based on molecular subtypes
TW202228794A (zh) 2020-09-04 2022-08-01 美商艾瑞岡醫藥公司 用於治療前列腺癌之方法
WO2022195407A1 (en) 2021-03-19 2022-09-22 Aragon Pharmaceuticals, Inc. Methods for treating prostate cancer
WO2023152611A1 (en) 2022-02-11 2023-08-17 Aragon Pharmaceuticals, Inc. Apalutamide and relugolix for the treatment of prostate cancer
WO2023209555A1 (en) 2022-04-26 2023-11-02 Aragon Pharmaceuticals, Inc. Approved drug products and methods for treating prostate cancer
WO2024189186A1 (en) 2023-03-16 2024-09-19 Bayer Consumer Care Ag Androgen receptor antagonists for the treatment of patients with biochemical recurrence of hormone sensitive prostate cancer

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DK0633893T3 (da) 1992-03-31 2000-04-17 Btg Int Ltd 17-Substituerede steroider, der er nyttige ved cancerbehandling
PT901786E (pt) 1997-08-11 2007-08-07 Pfizer Prod Inc Disperções farmacêuticas sólidas com biodisponibilidade melhorada
WO2001060410A1 (fr) 2000-02-21 2001-08-23 Takeda Chemical Industries, Ltd. Preparations a liberation lente contenant un compose physiologiquement actif peu soluble dans l'eau et methode de production et d'utilisation desdites preparations
HUP0302847A3 (en) 2001-02-27 2005-05-30 Astrazeneca Ab Pharmaceutical formulation comprising bicalutamide
ATE324886T1 (de) 2001-04-02 2006-06-15 Astrazeneca Ab Feste arzneizusammensetzung enthaltend 4'-cyano- trifluoro-3-(4-fluorophenylsulphonyl) -2-hydroxy- 2-methylpropiono- m toluidide und pvp
OA12624A (en) 2001-06-22 2006-06-12 Pfizer Prod Inc Pharmaceutical compositions comprising low-solubility and/or acid-sensitive drugs and neutralized acidic polymers.
SE0103424D0 (sv) 2001-10-15 2001-10-15 Astrazeneca Ab Pharmaceutical formulation
EP1469830A2 (en) 2002-02-01 2004-10-27 Pfizer Products Inc. Method for making homogeneous spray-dried solid amorphous drug dispersions using pressure nozzles
JPWO2003077827A1 (ja) 2002-03-19 2005-07-14 日本新薬株式会社 医薬固体分散体の製造方法
CN1878539B (zh) 2003-12-15 2010-06-23 科学与工业研究委员会 含苦味药物和pH敏感性聚合物的掩味的药物组合物
PT3412290T (pt) 2006-03-27 2021-04-19 Univ California Modulador do recetor de androgénios para o tratamento de cancro da próstata e doenças associadas ao recetor de androgénios
SG173178A1 (en) * 2009-04-03 2011-09-29 Hoffmann La Roche Propane- i-sulfonic acid {3- [5- (4 -chloro-phenyl) -1h-pyrrolo [2, 3-b] pyridine-3-carbonyl] -2, 4-difluoro-pheny l } -amide compositions and uses thereof
EA028869B1 (ru) 2010-02-16 2018-01-31 Арагон Фармасьютикалс, Инк. Модуляторы рецептора андрогенов и их применение
CN102525876B (zh) * 2010-12-15 2014-03-12 西安力邦医药科技有限责任公司 阿司匹林固体分散体、其制备方法、药物组合物和用途
AU2012271403C1 (en) 2011-06-15 2018-02-08 The United States Of America, As Represented By The Secretary, Department Of Health And Human Services Nuclear receptor modulators and their use for the treatment and prevention of cancer
US20150037407A1 (en) 2012-03-21 2015-02-05 Emphascience, Inc. Method to improve the safety of handling of high potency drugs in solid dosage forms without changing their efficacy
WO2013152342A1 (en) * 2012-04-06 2013-10-10 OSI Pharmaceuticals, LLC Anti-cancer mtor inhibitor and anti-androgen combination
PE20150631A1 (es) 2012-06-07 2015-05-11 Aragon Pharmaceuticals Inc Formas cristalinas de un modulador del receptor androgenico
US10668156B2 (en) 2012-06-22 2020-06-02 Basf Se Active-ingredient-containing solid dispersions based on diethylaminoethyl methacrylate copolymers
MX2015002430A (es) 2012-08-24 2015-06-22 Dow Global Technologies Llc Acetato-succinatos de hidroxialquilmetilcelulosa.
DK3725778T3 (da) 2012-09-11 2021-09-20 Medivation Prostate Therapeutics Llc Formuleringer af enzalutamid
US9977033B2 (en) 2012-09-11 2018-05-22 The Board Of Regents Of The University Of Texas System Methods for assessing cancer recurrence
NZ745682A (en) * 2012-09-26 2019-09-27 Aragon Pharmaceuticals Inc Anti-androgens for the treatment of non-metastatic castrate-resistant prostate cancer
JOP20200097A1 (ar) 2013-01-15 2017-06-16 Aragon Pharmaceuticals Inc معدل مستقبل أندروجين واستخداماته
NZ708272A (en) 2013-01-22 2020-07-31 Hoffmann La Roche Pharmaceutical composition with improved bioavailability
KR20160023641A (ko) 2013-03-15 2016-03-03 아이슈티카 인코포레이티드 아비라테론 아세테이트 제제
WO2014167428A2 (en) 2013-04-10 2014-10-16 Shilpa Medicare Limited Amorphous 4-(3-(4-cyano-3-(trifluoromethyl)phenyl)-5,5-dimethyl-4-oxo-2-thioxoimidazolidin-1-yl)-2-fluoro-n-methylbenzamide
KR20160058774A (ko) 2013-08-12 2016-05-25 토카이 파마슈티컬, 아이엔씨. 안드로겐-표적 치료제를 이용하는 종양 질환 치료를 위한 바이오마커
WO2015116696A1 (en) * 2014-01-28 2015-08-06 Massachusetts Institute Of Technology Combination therapies and methods of use thereof for treating cancer
CN106102716A (zh) 2014-02-05 2016-11-09 斯洛文尼亚莱柯制药股份有限公司 雄激素受体拮抗剂的固体药物组合物
BR112016018288A2 (pt) 2014-02-06 2017-10-10 Hoffmann La Roche proteínas de fusão de interleucina 2 e uso das mesmas
TWI718102B (zh) 2014-08-08 2021-02-11 日商中外製藥股份有限公司 4環性化合物的非晶質體
MA41107A (fr) 2014-12-05 2017-10-10 Aragon Pharmaceuticals Inc Compositions anti-cancéreuses
MD3226843T2 (ro) 2014-12-05 2021-10-31 Aragon Pharmaceuticals Inc Compoziții anticancer
CA2969661C (en) 2014-12-05 2023-04-25 Aragon Pharmaceuticals, Inc. Anticancer compositions
AR108489A1 (es) * 2016-06-03 2018-08-29 Aragon Pharmaceuticals Inc Composiciones antineoplásicas

Also Published As

Publication number Publication date
US11911511B2 (en) 2024-02-27
EP3226843B1 (en) 2021-05-26
UA123538C2 (uk) 2021-04-21
US11224575B2 (en) 2022-01-18
MX2017007206A (es) 2018-01-30
ES2883187T3 (es) 2021-12-07
EP3226843A1 (en) 2017-10-11
BR112017011726A2 (pt) 2017-12-26
LT3226843T (lt) 2021-08-10
JP2017536407A (ja) 2017-12-07
CL2017001373A1 (es) 2018-01-05
US20190209477A1 (en) 2019-07-11
HUE054935T2 (hu) 2021-10-28
TW201636019A (zh) 2016-10-16
US20170360713A1 (en) 2017-12-21
CY1124504T1 (el) 2022-07-22
RS62421B1 (sr) 2021-10-29
US10285948B2 (en) 2019-05-14
EA201791251A1 (ru) 2017-11-30
EP3925598A1 (en) 2021-12-22
DK3226843T3 (da) 2021-08-16
MD3226843T2 (ro) 2021-10-31
WO2016090105A1 (en) 2016-06-09
CO2017005574A2 (es) 2017-09-29
US20210308060A1 (en) 2021-10-07
CN106999432A (zh) 2017-08-01
PL3226843T3 (pl) 2021-12-13
MA41111B1 (fr) 2021-09-30
NI201700068A (es) 2017-09-11
TWI709403B (zh) 2020-11-11
IL252325A0 (en) 2017-07-31
KR20170086658A (ko) 2017-07-26
KR102387089B1 (ko) 2022-04-14
JP6830892B2 (ja) 2021-02-17
AU2015358497B2 (en) 2021-04-29
AU2015358497A1 (en) 2017-06-08
PH12017500979A1 (en) 2017-11-27
AR102925A1 (es) 2017-04-05
MY192931A (en) 2022-09-15
SI3226843T1 (sl) 2021-11-30
CA2969675C (en) 2023-06-06
HRP20211140T1 (hr) 2021-10-15
SG11201704386VA (en) 2017-06-29
CA2969675A1 (en) 2016-06-09
CR20170218A (es) 2017-08-30

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