ES2777533T3 - Lípidos oxidados y sus métodos de uso - Google Patents

Lípidos oxidados y sus métodos de uso Download PDF

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Publication number
ES2777533T3
ES2777533T3 ES15862487T ES15862487T ES2777533T3 ES 2777533 T3 ES2777533 T3 ES 2777533T3 ES 15862487 T ES15862487 T ES 15862487T ES 15862487 T ES15862487 T ES 15862487T ES 2777533 T3 ES2777533 T3 ES 2777533T3
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ES
Spain
Prior art keywords
group
fibrosis
compound
alkyl
formula
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
ES15862487T
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English (en)
Spanish (es)
Inventor
Eti Kovalevski Ishai
Itzhak Mendel
Yaniv Salem
Niva Yacov
Eyal Breitbart
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Notable Labs Ltd
Original Assignee
Vascular Biogenics Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
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Publication date
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Publication of ES2777533T3 publication Critical patent/ES2777533T3/es
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Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02Phosphorus compounds
    • C07F9/547Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/553Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having one nitrogen atom as the only ring hetero atom
    • C07F9/576Six-membered rings
    • C07F9/58Pyridine rings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/66Phosphorus compounds
    • A61K31/661Phosphorus acids or esters thereof not having P—C bonds, e.g. fosfosal, dichlorvos, malathion or mevinphos
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • A61P19/04Drugs for skeletal disorders for non-specific disorders of the connective tissue
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02ATECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Rheumatology (AREA)
  • Pain & Pain Management (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
ES15862487T 2014-11-26 2015-11-26 Lípidos oxidados y sus métodos de uso Active ES2777533T3 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201462085153P 2014-11-26 2014-11-26
PCT/IB2015/059134 WO2016084024A1 (en) 2014-11-26 2015-11-26 Oxidized lipids and methods of use thereof

Publications (1)

Publication Number Publication Date
ES2777533T3 true ES2777533T3 (es) 2020-08-05

Family

ID=56073714

Family Applications (1)

Application Number Title Priority Date Filing Date
ES15862487T Active ES2777533T3 (es) 2014-11-26 2015-11-26 Lípidos oxidados y sus métodos de uso

Country Status (8)

Country Link
US (2) US9771385B2 (https=)
EP (1) EP3223806B1 (https=)
JP (1) JP6637044B2 (https=)
CN (1) CN106999447B (https=)
CA (1) CA2968504A1 (https=)
ES (1) ES2777533T3 (https=)
IL (1) IL252508A0 (https=)
WO (1) WO2016084024A1 (https=)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9771385B2 (en) 2014-11-26 2017-09-26 Vascular Biogenics Ltd. Oxidized lipids
EP3223824B1 (en) 2014-11-26 2021-01-06 Vascular Biogenics Ltd. Oxidized lipids and treatment or prevention of fibrosis
WO2021199003A1 (en) * 2020-04-02 2021-10-07 Vascular Biogenics Ltd. Oxidized lipids and treatment or prevention of inflammation or infectious disease caused by coronavirus infection

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Also Published As

Publication number Publication date
WO2016084024A1 (en) 2016-06-02
JP6637044B2 (ja) 2020-01-29
EP3223806A4 (en) 2018-02-21
EP3223806A1 (en) 2017-10-04
CN106999447A (zh) 2017-08-01
CN106999447B (zh) 2020-10-30
EP3223806B1 (en) 2020-01-15
US20170369516A1 (en) 2017-12-28
JP2017537094A (ja) 2017-12-14
IL252508A0 (en) 2017-07-31
CA2968504A1 (en) 2016-06-02
US10464957B2 (en) 2019-11-05
US9771385B2 (en) 2017-09-26
US20160304544A1 (en) 2016-10-20

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