CA2968504A1 - Oxidized lipids and methods of use thereof - Google Patents

Oxidized lipids and methods of use thereof Download PDF

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Publication number
CA2968504A1
CA2968504A1 CA2968504A CA2968504A CA2968504A1 CA 2968504 A1 CA2968504 A1 CA 2968504A1 CA 2968504 A CA2968504 A CA 2968504A CA 2968504 A CA2968504 A CA 2968504A CA 2968504 A1 CA2968504 A1 CA 2968504A1
Authority
CA
Canada
Prior art keywords
compound
group
fibrosis
alkyl
butyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA2968504A
Other languages
English (en)
French (fr)
Inventor
Eti Kovalevski ISHAI
Itzhak Mendel
Yaniv Salem
Niva Yacov
Eyal Breitbart
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Notable Labs Ltd
Original Assignee
Vascular Biogenics Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Vascular Biogenics Ltd filed Critical Vascular Biogenics Ltd
Publication of CA2968504A1 publication Critical patent/CA2968504A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/553—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having one nitrogen atom as the only ring hetero atom
    • C07F9/576—Six-membered rings
    • C07F9/58—Pyridine rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/66—Phosphorus compounds
    • A61K31/661—Phosphorus acids or esters thereof not having P—C bonds, e.g. fosfosal, dichlorvos, malathion or mevinphos
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/04—Drugs for skeletal disorders for non-specific disorders of the connective tissue
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Rheumatology (AREA)
  • Pain & Pain Management (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
CA2968504A 2014-11-26 2015-11-26 Oxidized lipids and methods of use thereof Abandoned CA2968504A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201462085153P 2014-11-26 2014-11-26
US62/085,153 2014-11-26
PCT/IB2015/059134 WO2016084024A1 (en) 2014-11-26 2015-11-26 Oxidized lipids and methods of use thereof

Publications (1)

Publication Number Publication Date
CA2968504A1 true CA2968504A1 (en) 2016-06-02

Family

ID=56073714

Family Applications (1)

Application Number Title Priority Date Filing Date
CA2968504A Abandoned CA2968504A1 (en) 2014-11-26 2015-11-26 Oxidized lipids and methods of use thereof

Country Status (8)

Country Link
US (2) US9771385B2 (https=)
EP (1) EP3223806B1 (https=)
JP (1) JP6637044B2 (https=)
CN (1) CN106999447B (https=)
CA (1) CA2968504A1 (https=)
ES (1) ES2777533T3 (https=)
IL (1) IL252508A0 (https=)
WO (1) WO2016084024A1 (https=)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9771385B2 (en) 2014-11-26 2017-09-26 Vascular Biogenics Ltd. Oxidized lipids
EP3223824B1 (en) 2014-11-26 2021-01-06 Vascular Biogenics Ltd. Oxidized lipids and treatment or prevention of fibrosis
WO2021199003A1 (en) * 2020-04-02 2021-10-07 Vascular Biogenics Ltd. Oxidized lipids and treatment or prevention of inflammation or infectious disease caused by coronavirus infection

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Also Published As

Publication number Publication date
WO2016084024A1 (en) 2016-06-02
JP6637044B2 (ja) 2020-01-29
EP3223806A4 (en) 2018-02-21
EP3223806A1 (en) 2017-10-04
CN106999447A (zh) 2017-08-01
CN106999447B (zh) 2020-10-30
EP3223806B1 (en) 2020-01-15
US20170369516A1 (en) 2017-12-28
JP2017537094A (ja) 2017-12-14
IL252508A0 (en) 2017-07-31
ES2777533T3 (es) 2020-08-05
US10464957B2 (en) 2019-11-05
US9771385B2 (en) 2017-09-26
US20160304544A1 (en) 2016-10-20

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Effective date: 20201123

FZDE Discontinued

Effective date: 20240205