ES2707977T5 - Método de detección de cáncer mediante el sentido del olfato del nematodo - Google Patents
Método de detección de cáncer mediante el sentido del olfato del nematodo Download PDFInfo
- Publication number
- ES2707977T5 ES2707977T5 ES14870595T ES14870595T ES2707977T5 ES 2707977 T5 ES2707977 T5 ES 2707977T5 ES 14870595 T ES14870595 T ES 14870595T ES 14870595 T ES14870595 T ES 14870595T ES 2707977 T5 ES2707977 T5 ES 2707977T5
- Authority
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- Spain
- Prior art keywords
- cancer
- nematode
- nematodes
- receptor
- diacetyl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/575—Immunoassay; Biospecific binding assay; Materials therefor for cancer
- G01N33/5758—Immunoassay; Biospecific binding assay; Materials therefor for cancer involving compounds serving as markers for tumours, cancers or neoplasias, e.g. cellular determinants, receptors, heat shock/stress proteins, A-protein, oligosaccharides or metabolites
- G01N33/57585—Immunoassay; Biospecific binding assay; Materials therefor for cancer involving compounds serving as markers for tumours, cancers or neoplasias, e.g. cellular determinants, receptors, heat shock/stress proteins, A-protein, oligosaccharides or metabolites involving compounds identifiable in body fluids
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
- C12Q1/6888—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for detection or identification of organisms
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/112—Disease subtyping, staging or classification
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/158—Expression markers
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
- G01N2333/43504—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans from invertebrates
- G01N2333/43526—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans from invertebrates from worms
- G01N2333/4353—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans from invertebrates from worms from nematodes
- G01N2333/43534—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans from invertebrates from worms from nematodes from Caenorhabditis
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2800/00—Detection or diagnosis of diseases
- G01N2800/50—Determining the risk of developing a disease
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Immunology (AREA)
- Molecular Biology (AREA)
- Analytical Chemistry (AREA)
- Urology & Nephrology (AREA)
- Biomedical Technology (AREA)
- Hematology (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- Microbiology (AREA)
- Biotechnology (AREA)
- Physics & Mathematics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Organic Chemistry (AREA)
- Cell Biology (AREA)
- Medicinal Chemistry (AREA)
- General Physics & Mathematics (AREA)
- Pathology (AREA)
- Food Science & Technology (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Biophysics (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- Genetics & Genomics (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Peptides Or Proteins (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2013255145 | 2013-12-10 | ||
| US201461982341P | 2014-04-22 | 2014-04-22 | |
| PCT/JP2014/083320 WO2015088039A1 (ja) | 2013-12-10 | 2014-12-10 | 線虫の嗅覚を用いた癌検出法 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| ES2707977T3 ES2707977T3 (es) | 2019-04-08 |
| ES2707977T5 true ES2707977T5 (es) | 2024-04-18 |
Family
ID=53371333
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES14870595T Active ES2707977T5 (es) | 2013-12-10 | 2014-12-10 | Método de detección de cáncer mediante el sentido del olfato del nematodo |
Country Status (13)
| Country | Link |
|---|---|
| US (3) | US11719698B2 (enExample) |
| EP (1) | EP3081935B2 (enExample) |
| JP (6) | JP6336481B2 (enExample) |
| KR (1) | KR102247737B1 (enExample) |
| CN (1) | CN106255877B (enExample) |
| DK (1) | DK3081935T4 (enExample) |
| ES (1) | ES2707977T5 (enExample) |
| FI (1) | FI3081935T4 (enExample) |
| HR (1) | HRP20190338T4 (enExample) |
| MY (1) | MY172330A (enExample) |
| PT (1) | PT3081935T (enExample) |
| SG (2) | SG11201604743QA (enExample) |
| WO (1) | WO2015088039A1 (enExample) |
Families Citing this family (44)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP6522778B2 (ja) * | 2015-11-10 | 2019-05-29 | 株式会社日立製作所 | 癌検査システム及び癌検査評価方法 |
| US11443851B2 (en) * | 2015-11-30 | 2022-09-13 | Hirotsu Bio Science Inc. | Cancer test system and method for assessing cancer test |
| JP6556063B2 (ja) * | 2016-01-25 | 2019-08-07 | 株式会社日立製作所 | 保険システム、情報提供サーバ及び保険リスク算出方法 |
| WO2017149626A1 (ja) * | 2016-02-29 | 2017-09-08 | 株式会社日立製作所 | がん解析システム及びがん解析方法 |
| KR101907151B1 (ko) * | 2016-05-18 | 2018-10-12 | 이동선 | 디아세틸을 포함하는, 암 줄기세포 성장 억제용 조성물 |
| WO2017213246A1 (ja) | 2016-06-10 | 2017-12-14 | 株式会社日立製作所 | 尿中代謝物による疾病診断法 |
| JP6747908B2 (ja) * | 2016-08-09 | 2020-08-26 | 株式会社Ｈｉｒｏｔｓｕバイオサイエンス | バッファ吸取装置及びがん解析システム |
| WO2018047959A1 (ja) * | 2016-09-12 | 2018-03-15 | 株式会社Ｈｉｒｏｔｓｕバイオサイエンス | 線虫の嗅覚に基づく匂い物質に対する走性行動の評価方法、並びに該評価方法に用いるシャーレおよび行動評価系 |
| JP6164622B1 (ja) * | 2016-09-12 | 2017-07-19 | 株式会社Ｈｉｒｏｔｓｕバイオサイエンス | 線虫の嗅覚に基づく匂い物質に対する走性行動の評価方法、および該評価方法に用いるシャーレ |
| JP7076199B2 (ja) * | 2016-12-01 | 2022-05-27 | 株式会社Ｈｉｒｏｔｓｕバイオサイエンス | 匂い物質の検出方法 |
| JP7045680B2 (ja) * | 2017-02-16 | 2022-04-01 | 国立大学法人東北大学 | 線虫を用いた物質の生理活性評価法 |
| JP6788921B2 (ja) * | 2017-03-31 | 2020-11-25 | 株式会社Ｈｉｒｏｔｓｕバイオサイエンス | 線虫の嗅覚の感度を向上させる化合物 |
| WO2018181869A1 (ja) * | 2017-03-31 | 2018-10-04 | 株式会社Ｈｉｒｏｔｓｕバイオサイエンス | 線虫変異体を含むがんの診断薬および該変異体を用いた走性行動評価方法 |
| CN117347612A (zh) * | 2017-03-31 | 2024-01-05 | 广津生物科学株式会社 | 癌患者的治疗效果的预测和/或复发监测 |
| JP7100323B2 (ja) * | 2017-07-11 | 2022-07-13 | 株式会社Ｈｉｒｏｔｓｕバイオサイエンス | 組織検体を用いたがんの検出方法 |
| WO2019039415A1 (ja) | 2017-08-21 | 2019-02-28 | 株式会社Ｈｉｒｏｔｓｕバイオサイエンス | 腎臓がんの検出方法 |
| IT201700119113A1 (it) * | 2017-10-20 | 2019-04-20 | Crestoptics S P A | Apparato e metodo per il rilevamento automatizzato di sostanze odoranti in soluzione tramite impiego di nematodi Chaenorabditis Elegans |
| WO2019081551A1 (en) | 2017-10-26 | 2019-05-02 | Merck Patent Gmbh | METHOD FOR REALIZING A CHEMOTAXIS ASSAY ON A POROUS WET SURFACE |
| WO2020036187A1 (ja) | 2018-08-14 | 2020-02-20 | 株式会社Ｈｉｒｏｔｓｕバイオサイエンス | ペットにおけるがんの検査方法 |
| JP7442785B2 (ja) * | 2019-12-06 | 2024-03-05 | 株式会社Ｈｉｒｏｔｓｕバイオサイエンス | 走性解析方法、がん評価方法、走性解析システム及びプログラム |
| US12017506B2 (en) | 2020-08-20 | 2024-06-25 | Denso International America, Inc. | Passenger cabin air control systems and methods |
| US11760170B2 (en) | 2020-08-20 | 2023-09-19 | Denso International America, Inc. | Olfaction sensor preservation systems and methods |
| US11932080B2 (en) | 2020-08-20 | 2024-03-19 | Denso International America, Inc. | Diagnostic and recirculation control systems and methods |
| US11828210B2 (en) | 2020-08-20 | 2023-11-28 | Denso International America, Inc. | Diagnostic systems and methods of vehicles using olfaction |
| US11636870B2 (en) | 2020-08-20 | 2023-04-25 | Denso International America, Inc. | Smoking cessation systems and methods |
| US11760169B2 (en) | 2020-08-20 | 2023-09-19 | Denso International America, Inc. | Particulate control systems and methods for olfaction sensors |
| US12377711B2 (en) | 2020-08-20 | 2025-08-05 | Denso International America, Inc. | Vehicle feature control systems and methods based on smoking |
| US12269315B2 (en) | 2020-08-20 | 2025-04-08 | Denso International America, Inc. | Systems and methods for measuring and managing odor brought into rental vehicles |
| US11813926B2 (en) | 2020-08-20 | 2023-11-14 | Denso International America, Inc. | Binding agent and olfaction sensor |
| US11881093B2 (en) | 2020-08-20 | 2024-01-23 | Denso International America, Inc. | Systems and methods for identifying smoking in vehicles |
| US12251991B2 (en) | 2020-08-20 | 2025-03-18 | Denso International America, Inc. | Humidity control for olfaction sensors |
| WO2022107736A1 (ja) | 2020-11-17 | 2022-05-27 | 株式会社Ｈｉｒｏｔｓｕバイオサイエンス | 線虫の走性行動による血液試料の検査方法 |
| JP7627471B6 (ja) * | 2021-02-03 | 2025-03-07 | ディスラプティブ テクノロジカル アドバンシス イン ライフ サイエンス エッセ．エッレ．エッレ． － ソシエタ’ ベネフィット、イン フォルマ アブレヴィアータ、ディ － テールズ エッセ．エッレ．エッレ．エッセビ | がん検出方法 |
| IL283262A (en) * | 2021-05-18 | 2022-12-01 | Gillui Saving Lives Ltd | An automated diagnostic system comprising rodents |
| JP7464285B2 (ja) | 2021-07-08 | 2024-04-09 | 学校法人 名城大学 | マイクロ流体デバイス |
| KR20240087731A (ko) * | 2021-08-24 | 2024-06-19 | 온코텍트, 인코포레이티드 | 반려 동물의 암 스크리닝 |
| IL285830A (en) * | 2021-08-24 | 2022-07-01 | Early O M Ltd | Volatile organic compounds (voc’s) diagnosis system |
| EP4446412A4 (en) | 2021-12-08 | 2026-03-04 | National Institutes For Quantum Science And Tech | Nematode-sealed capsule, method for producing nematode-sealed capsule, and use of nematode-sealed capsule |
| CN117678573A (zh) * | 2023-11-01 | 2024-03-12 | 壮子恒 | 使用线虫的嗅觉的孤独谱系障碍检测方法 |
| JP7734807B1 (ja) | 2024-08-09 | 2025-09-05 | 住友化学株式会社 | 判定方法、判定装置及びコンピュータプログラム |
| JP2026031369A (ja) * | 2024-08-09 | 2026-02-24 | 住友化学株式会社 | がんの検査剤 |
| JP7631607B1 (ja) | 2024-08-09 | 2025-02-18 | 住友化学株式会社 | 嗅覚受容体タンパク質又はその組み合わせのスクリーニング方法 |
| JP7712444B1 (ja) | 2024-08-09 | 2025-07-23 | 住友化学株式会社 | 判定方法、判定装置及びコンピュータプログラム |
| CN121040468A (zh) * | 2025-11-03 | 2025-12-02 | 云南大学 | 一种吡嗪类化合物在制备植物寄生线虫引诱剂上的应用 |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH11215934A (ja) * | 1998-01-30 | 1999-08-10 | Sanyo Electric Co Ltd | 探索物質に基いて特異行動を示す生物体、これを用いた物質探索方法及び物質処理方法 |
| US20100248268A1 (en) | 2001-03-27 | 2010-09-30 | Woods Daniel F | Methods to utilize invertebrate chemosensory proteins for industrial and commercial uses |
| WO2004033654A2 (en) * | 2002-10-09 | 2004-04-22 | Buck Institute | Automated method for high throughput screening of nematodes |
| JP5307565B2 (ja) | 2009-01-19 | 2013-10-02 | 独立行政法人科学技術振興機構 | ドーパミンシグナル伝達阻害剤のスクリーニング方法、スクリーニング用組成物及び組成物 |
| IT201700119113A1 (it) | 2017-10-20 | 2019-04-20 | Crestoptics S P A | Apparato e metodo per il rilevamento automatizzato di sostanze odoranti in soluzione tramite impiego di nematodi Chaenorabditis Elegans |
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2014
- 2014-12-10 JP JP2015552555A patent/JP6336481B2/ja active Active
- 2014-12-10 WO PCT/JP2014/083320 patent/WO2015088039A1/ja not_active Ceased
- 2014-12-10 CN CN201480075291.9A patent/CN106255877B/zh active Active
- 2014-12-10 SG SG11201604743QA patent/SG11201604743QA/en unknown
- 2014-12-10 SG SG10201900889WA patent/SG10201900889WA/en unknown
- 2014-12-10 MY MYPI2016001088A patent/MY172330A/en unknown
- 2014-12-10 US US15/103,264 patent/US11719698B2/en active Active
- 2014-12-10 ES ES14870595T patent/ES2707977T5/es active Active
- 2014-12-10 PT PT14870595T patent/PT3081935T/pt unknown
- 2014-12-10 EP EP14870595.7A patent/EP3081935B2/en active Active
- 2014-12-10 FI FIEP14870595.7T patent/FI3081935T4/fi active
- 2014-12-10 HR HRP20190338TT patent/HRP20190338T4/hr unknown
- 2014-12-10 KR KR1020167018261A patent/KR102247737B1/ko active Active
- 2014-12-10 DK DK14870595.7T patent/DK3081935T4/da active
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2018
- 2018-01-10 JP JP2018001996A patent/JP6629358B2/ja active Active
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2019
- 2019-10-23 JP JP2019192813A patent/JP6802341B6/ja active Active
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2020
- 2020-11-26 JP JP2020196320A patent/JP7111791B2/ja active Active
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2021
- 2021-04-27 US US17/241,947 patent/US20210356470A1/en active Pending
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2022
- 2022-07-19 JP JP2022114543A patent/JP7520921B2/ja active Active
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2023
- 2023-03-09 US US18/119,405 patent/US12493040B2/en active Active
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2024
- 2024-07-10 JP JP2024111212A patent/JP7770483B2/ja active Active
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