ES2671631T3 - Proteína de fusión de lactoferrina y método para la preparación de la misma - Google Patents
Proteína de fusión de lactoferrina y método para la preparación de la misma Download PDFInfo
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- ES2671631T3 ES2671631T3 ES13780579.2T ES13780579T ES2671631T3 ES 2671631 T3 ES2671631 T3 ES 2671631T3 ES 13780579 T ES13780579 T ES 13780579T ES 2671631 T3 ES2671631 T3 ES 2671631T3
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- fusion protein
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- lactoferrin
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- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/82—Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
- C12N15/8241—Phenotypically and genetically modified plants via recombinant DNA technology
- C12N15/8242—Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits
- C12N15/8257—Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits for the production of primary gene products, e.g. pharmaceutical products, interferon
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- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
- A01K2217/00—Genetically modified animals
- A01K2217/05—Animals comprising random inserted nucleic acids (transgenic)
- A01K2217/052—Animals comprising random inserted nucleic acids (transgenic) inducing gain of function
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
- A01K2267/00—Animals characterised by purpose
- A01K2267/01—Animal expressing industrially exogenous proteins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/30—Non-immunoglobulin-derived peptide or protein having an immunoglobulin constant or Fc region, or a fragment thereof, attached thereto
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- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Genetics & Genomics (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Biomedical Technology (AREA)
- Zoology (AREA)
- Molecular Biology (AREA)
- Biotechnology (AREA)
- General Engineering & Computer Science (AREA)
- Wood Science & Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Environmental Sciences (AREA)
- Diabetes (AREA)
- Physics & Mathematics (AREA)
- Plant Pathology (AREA)
- Microbiology (AREA)
- Gastroenterology & Hepatology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Immunology (AREA)
- Hematology (AREA)
- Pain & Pain Management (AREA)
- Toxicology (AREA)
- Biodiversity & Conservation Biology (AREA)
- Animal Husbandry (AREA)
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Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2012098085 | 2012-04-23 | ||
| JP2012098085 | 2012-04-23 | ||
| PCT/JP2013/062685 WO2013162050A1 (ja) | 2012-04-23 | 2013-04-23 | ラクトフェリン融合タンパク質及びその製造方法 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES2671631T3 true ES2671631T3 (es) | 2018-06-07 |
Family
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| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES13780579.2T Active ES2671631T3 (es) | 2012-04-23 | 2013-04-23 | Proteína de fusión de lactoferrina y método para la preparación de la misma |
Country Status (9)
| Country | Link |
|---|---|
| US (2) | US9809641B2 (enExample) |
| EP (1) | EP2842969B1 (enExample) |
| JP (2) | JP5855239B2 (enExample) |
| KR (1) | KR102177252B1 (enExample) |
| BR (1) | BR112014026162A2 (enExample) |
| CA (1) | CA2871468C (enExample) |
| ES (1) | ES2671631T3 (enExample) |
| IN (1) | IN2014DN09815A (enExample) |
| WO (1) | WO2013162050A1 (enExample) |
Families Citing this family (13)
| Publication number | Priority date | Publication date | Assignee | Title |
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| WO2013162050A1 (ja) * | 2012-04-23 | 2013-10-31 | 株式会社Ｎｒｌファーマ | ラクトフェリン融合タンパク質及びその製造方法 |
| EA037256B1 (ru) * | 2014-02-24 | 2021-02-26 | Такеда Гмбх | Химерный белок мочевого трипсинового ингибитора (мти), содержащий домен мти и fc-домен igg1 |
| EP3291670A1 (en) * | 2015-05-04 | 2018-03-14 | Laboratoire Français du Fractionnement et des Biotechnologies | Transgenic production of fc fusion proteins |
| EP3313875A4 (en) | 2015-06-24 | 2018-12-26 | Board of Regents of the University of Texas System | Methods and compositions for treatment of symptoms associated with intracranial hemorrhage |
| PT3355913T (pt) * | 2015-09-30 | 2024-12-18 | Igm Biosciences Inc | Moléculas de ligação com cadeia j modificada |
| WO2018079701A1 (ja) * | 2016-10-28 | 2018-05-03 | 株式会社Ｎｒｌファーマ | ラクトフェリン活性を有するタンパク質を含む、抗ガン治療補助剤 |
| EP3533870A4 (en) * | 2016-10-28 | 2020-04-08 | NRL Pharma, Inc. | LACTOFERRIN / ALBUMIN FUSION PROTEIN AND PROCESS FOR PRODUCING THE SAME |
| SI3583120T1 (sl) | 2017-02-17 | 2023-02-28 | Denali Therapeutics Inc. | Inženirani polipeptidi, ki vezujejo transferinske receptorje |
| CR20200129A (es) | 2017-10-02 | 2020-08-22 | Denali Therapeutics Inc | Proteínas de fusión que comprenden enzimas de terapia de reemplazo de enzimas |
| CN112351791A (zh) * | 2018-06-26 | 2021-02-09 | S&K生物制药有限公司 | 糖胺聚糖抑制剂和促进剂 |
| US20200024329A1 (en) * | 2018-07-17 | 2020-01-23 | Bradley G. Thompson | Methods for regulating endogenous production of lactoferrin and sub-peptides thereof |
| CA3165846A1 (en) | 2019-12-23 | 2021-07-01 | Denali Therapeutics Inc. | Progranulin variants |
| JP2023551821A (ja) * | 2020-11-25 | 2023-12-13 | アヴァイルス，インコーポレイテッド | ウイルス感染を治療するための方法及び組成物 |
Family Cites Families (18)
| Publication number | Priority date | Publication date | Assignee | Title |
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| US5723125A (en) | 1995-12-28 | 1998-03-03 | Tanox Biosystems, Inc. | Hybrid with interferon-alpha and an immunoglobulin Fc linked through a non-immunogenic peptide |
| US6111081A (en) * | 1996-05-31 | 2000-08-29 | Baylor College Of Medicine | Lactoferrin variants and uses thereof |
| US6423509B1 (en) | 1998-07-15 | 2002-07-23 | Samyang Genex Corporation | Pichia pastoris strain for producing lactoferrin and methods of use |
| US6660843B1 (en) * | 1998-10-23 | 2003-12-09 | Amgen Inc. | Modified peptides as therapeutic agents |
| EP2294930A3 (en) | 2001-02-14 | 2011-08-03 | Ventria Bioscience | Expression of human milk proteins in transgenic plants |
| CA2440221C (en) | 2001-03-07 | 2013-02-05 | Merck Patent Gesellschaft Mit Beschraenkter Haftung | Expression technology for proteins containing a hybrid isotype antibody moiety |
| KR100453877B1 (ko) | 2001-07-26 | 2004-10-20 | 메덱스젠 주식회사 | 연쇄체화에 의한 면역 글로블린 융합 단백질의 제조 방법 및 이 방법에 의해 제조된 ＴＮＦＲ/Ｆｃ 융합 단백질, 상기 단백질을 코딩하는 ＤＮＡ, 상기 ＤＮＡ를 포함하는벡터, 및 상기 벡터에 의한 형질전환체 |
| EP2239273B1 (en) * | 2003-11-13 | 2013-10-09 | Hanmi Science Co., Ltd. | A pharmaceutical composition comprosing an immunoglobulin fc as a carrier |
| JP2008509153A (ja) | 2004-08-03 | 2008-03-27 | バイオレクシス ファーマシューティカル コーポレイション | Ｇｌｐ−１を含むトランスフェリン融合タンパク質用いた併用療法 |
| JP4261531B2 (ja) | 2005-09-06 | 2009-04-30 | 株式会社Ｎｒｌファーマ | ラクトフェリン複合体及びその製造方法 |
| TW200843794A (en) * | 2006-12-21 | 2008-11-16 | Centocor Inc | Use of long-acting GLP-1 receptor agonists to improve insulin sensitivity and lipid profiles |
| US7867491B2 (en) | 2007-05-30 | 2011-01-11 | Genexine Co., Ltd. | Immunoglobulin fusion proteins |
| BRPI0910622A2 (pt) | 2008-04-25 | 2020-03-10 | Dyax Corp. | ANTICORPOS CONTRA FcRn E USOS DOS MESMOS |
| JP2010138160A (ja) | 2008-11-14 | 2010-06-24 | Nrl Pharma Inc | 肝機能保護医薬品組成物 |
| JP2010215522A (ja) | 2009-03-13 | 2010-09-30 | Nrl Pharma Inc | 皮膚疾患治療用又は皮膚疾患予防用医薬組成物、及び、皮膚疾患予防用化粧料 |
| WO2013162050A1 (ja) * | 2012-04-23 | 2013-10-31 | 株式会社Ｎｒｌファーマ | ラクトフェリン融合タンパク質及びその製造方法 |
| JP2015027981A (ja) | 2013-07-05 | 2015-02-12 | 富士フイルム株式会社 | 腸溶性細粒及び医薬組成物 |
| EP3533870A4 (en) | 2016-10-28 | 2020-04-08 | NRL Pharma, Inc. | LACTOFERRIN / ALBUMIN FUSION PROTEIN AND PROCESS FOR PRODUCING THE SAME |
-
2013
- 2013-04-23 WO PCT/JP2013/062685 patent/WO2013162050A1/ja not_active Ceased
- 2013-04-23 CA CA2871468A patent/CA2871468C/en active Active
- 2013-04-23 KR KR1020147031493A patent/KR102177252B1/ko active Active
- 2013-04-23 ES ES13780579.2T patent/ES2671631T3/es active Active
- 2013-04-23 US US14/395,826 patent/US9809641B2/en active Active
- 2013-04-23 JP JP2014512737A patent/JP5855239B2/ja active Active
- 2013-04-23 EP EP13780579.2A patent/EP2842969B1/en active Active
- 2013-04-23 BR BR112014026162A patent/BR112014026162A2/pt not_active Application Discontinuation
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2014
- 2014-11-19 IN IN9815DEN2014 patent/IN2014DN09815A/en unknown
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2015
- 2015-12-08 JP JP2015239725A patent/JP6356115B2/ja active Active
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2017
- 2017-09-29 US US15/720,023 patent/US10562959B2/en active Active
Also Published As
| Publication number | Publication date |
|---|---|
| KR102177252B1 (ko) | 2020-11-10 |
| KR20150008870A (ko) | 2015-01-23 |
| WO2013162050A1 (ja) | 2013-10-31 |
| US20150093382A1 (en) | 2015-04-02 |
| US10562959B2 (en) | 2020-02-18 |
| IN2014DN09815A (enExample) | 2015-07-31 |
| JP5855239B2 (ja) | 2016-02-09 |
| BR112014026162A2 (pt) | 2017-10-03 |
| CN104245739A (zh) | 2014-12-24 |
| US20180072794A1 (en) | 2018-03-15 |
| JPWO2013162050A1 (ja) | 2015-12-24 |
| JP2016117717A (ja) | 2016-06-30 |
| EP2842969A1 (en) | 2015-03-04 |
| JP6356115B2 (ja) | 2018-07-11 |
| CA2871468A1 (en) | 2013-10-31 |
| CA2871468C (en) | 2021-09-21 |
| EP2842969A4 (en) | 2016-01-13 |
| EP2842969B1 (en) | 2018-03-14 |
| US9809641B2 (en) | 2017-11-07 |
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