ES2653718T3 - Descubrimiento innovador de composiciones terapéuticas, de diagnóstico y de anticuerpos relacionadas con fragmentos de proteínas de histidil-ARNt sintetasas - Google Patents
Descubrimiento innovador de composiciones terapéuticas, de diagnóstico y de anticuerpos relacionadas con fragmentos de proteínas de histidil-ARNt sintetasas Download PDFInfo
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- ES2653718T3 ES2653718T3 ES11816760.0T ES11816760T ES2653718T3 ES 2653718 T3 ES2653718 T3 ES 2653718T3 ES 11816760 T ES11816760 T ES 11816760T ES 2653718 T3 ES2653718 T3 ES 2653718T3
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| US20120004185A1 (en) | 2009-02-27 | 2012-01-05 | Atyr Pharma, Inc. | Polypeptide structural motifs associated with cell signaling activity |
| ES2638779T3 (es) | 2009-03-16 | 2017-10-24 | Pangu Biopharma Limited | Composiciones y procedimientos que comprenden variantes de splicing de histidil-tarn sintetasa que tienen actividades biológicas no canónicas |
| CN106474462A (zh) | 2009-12-11 | 2017-03-08 | Atyr 医药公司 | 用于调节炎症的氨酰tRNA合成酶 |
| WO2011139714A2 (en) | 2010-04-26 | 2011-11-10 | Atyr Pharma, Inc. | Innovative discovery of therapeutic, diagnostic, and antibody compositions related to protein fragments of cysteinyl-trna synthetase |
| ES2638311T3 (es) | 2010-04-27 | 2017-10-19 | Atyr Pharma, Inc. | Descubrimiento innovador de composiciones terapéuticas, diagnósticas y de anticuerpos relacionadas con fragmentos de proteína de treonil ARNt sintetasas |
| AU2011248614B2 (en) | 2010-04-27 | 2017-02-16 | Pangu Biopharma Limited | Innovative discovery of therapeutic, diagnostic, and antibody compositions related to protein fragments of isoleucyl tRNA synthetases |
| US8993723B2 (en) | 2010-04-28 | 2015-03-31 | Atyr Pharma, Inc. | Innovative discovery of therapeutic, diagnostic, and antibody compositions related to protein fragments of alanyl-tRNA synthetases |
| US9068177B2 (en) | 2010-04-29 | 2015-06-30 | Atyr Pharma, Inc | Innovative discovery of therapeutic, diagnostic, and antibody compositions related to protein fragments of glutaminyl-tRNA synthetases |
| JP6008838B2 (ja) | 2010-04-29 | 2016-10-19 | エータイアー ファーマ， インコーポレイテッド | アスパラギニルｔＲＮＡ合成酵素のタンパク質フラグメントに関連した治療用、診断用および抗体組成物の革新的発見 |
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| JP5976638B2 (ja) | 2010-05-03 | 2016-08-23 | エータイアー ファーマ， インコーポレイテッド | アルギニルｔＲＮＡ合成酵素のタンパク質フラグメントに関連した治療用、診断用および抗体組成物の革新的発見 |
| EP2566496B1 (en) | 2010-05-03 | 2018-02-28 | aTyr Pharma, Inc. | Innovative discovery of therapeutic, diagnostic, and antibody compositions related to protein fragments of methionyl-trna synthetases |
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| EP2566516B1 (en) | 2010-05-03 | 2019-07-03 | aTyr Pharma, Inc. | Innovative discovery of therapeutic, diagnostic, and antibody compositions related to protein fragments of seryl-trna synthetases |
| AU2011248101B2 (en) | 2010-05-04 | 2016-10-20 | Atyr Pharma, Inc. | Innovative discovery of therapeutic, diagnostic, and antibody compositions related to protein fragments of p38 multi-tRNA synthetase complex |
| CN103096909A (zh) | 2010-05-04 | 2013-05-08 | Atyr医药公司 | 与谷氨酰-脯氨酰-tRNA合成酶的蛋白片段相关的治疗、诊断和抗体组合物的创新发现 |
| US8945541B2 (en) | 2010-05-14 | 2015-02-03 | Atyr Pharma, Inc. | Innovative discovery of therapeutic, diagnostic, and antibody compositions related to protein fragments of phenylalanyl-beta-tRNA synthetases |
| WO2011146410A2 (en) | 2010-05-17 | 2011-11-24 | Atyr Pharma, Inc. | Innovative discovery of therapeutic, diagnostic, and antibody compositions related to protein fragments of leucyl-trna synthetases |
| US8962560B2 (en) | 2010-06-01 | 2015-02-24 | Atyr Pharma Inc. | Innovative discovery of therapeutic, diagnostic, and antibody compositions related to protein fragments of Lysyl-tRNA synthetases |
| US20130202576A1 (en) | 2010-07-12 | 2013-08-08 | Pangu Biopharma Limited | Innovative discovery of therapeutic, diagnostic, and antibody compositions related to protein fragments of histidyl-trna synthetases |
| US8999321B2 (en) | 2010-07-12 | 2015-04-07 | Atyr Pharma, Inc. | Innovative discovery of therapeutic, diagnostic, and antibody compositions related to protein fragments of glycyl-tRNA synthetases |
| WO2012009289A2 (en) | 2010-07-12 | 2012-01-19 | Atyr Pharma, Inc. | Innovative discovery of therapeutic, diagnostic, and antibody compositions related to protein fragments of aspartyl-trna synthetases |
| AU2011289831C1 (en) | 2010-07-12 | 2017-06-15 | Pangu Biopharma Limited | Innovative discovery of therapeutic, diagnostic, and antibody compositions related to protein fragments of glycyl-tRNA synthetases |
| WO2012027611A2 (en) | 2010-08-25 | 2012-03-01 | Atyr Pharma, Inc. | INNOVATIVE DISCOVERY OF THERAPEUTIC, DIAGNOSTIC, AND ANTIBODY COMPOSITIONS RELATED TO PROTEIN FRAGMENTS OF TYROSYL-tRNA SYNTHETASES |
| US9399770B2 (en) | 2010-10-06 | 2016-07-26 | Atyr Pharma, Inc. | Innovative discovery of therapeutic, diagnostic, and antibody compositions related to protein fragments of tryptophanyl-tRNA synthetases |
| WO2013022982A2 (en) | 2011-08-09 | 2013-02-14 | Atyr Pharma, Inc. | Pegylated tyrosyl-trna synthetase polypeptides |
| WO2013086216A1 (en) | 2011-12-06 | 2013-06-13 | Atyr Pharma, Inc. | Improved aspartyl-trna synthetases |
| WO2013086228A1 (en) | 2011-12-06 | 2013-06-13 | Atyr Pharma, Inc. | Pegylated aspartyl-trna synthetase polypeptides |
| JP6169608B2 (ja) | 2011-12-29 | 2017-07-26 | エータイアー ファーマ， インコーポレイテッド | アスパルチルｔＲＮＡシンテターゼ−Ｆｃコンジュゲート |
| CN104334196B (zh) | 2012-02-16 | 2018-04-10 | Atyr 医药公司 | 用于治疗自身免疫疾病和炎性疾病的组氨酰‑tRNA合成酶 |
| AU2014233436B2 (en) | 2013-03-15 | 2019-12-05 | Atyr Pharma, Inc. | Histidyl-tRNA synthetase-Fc conjugates |
| CA2938015A1 (en) * | 2014-02-26 | 2015-09-03 | Chr. Hansen A/S | Variants of chymosin with improved milk-clotting properties |
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| EP2593126A4 (en) | 2014-08-06 |
| AU2011289833C1 (en) | 2017-06-15 |
| EA201390095A1 (ru) | 2013-06-28 |
| US10196628B2 (en) | 2019-02-05 |
| US20130202576A1 (en) | 2013-08-08 |
| CA2804424A1 (en) | 2012-02-16 |
| US20170029800A1 (en) | 2017-02-02 |
| NZ603813A (en) | 2015-03-27 |
| US9422539B2 (en) | 2016-08-23 |
| CN103108649A (zh) | 2013-05-15 |
| US20170321206A1 (en) | 2017-11-09 |
| KR20180059953A (ko) | 2018-06-05 |
| EA030418B1 (ru) | 2018-08-31 |
| US20150344866A1 (en) | 2015-12-03 |
| WO2012021249A2 (en) | 2012-02-16 |
| US10669533B2 (en) | 2020-06-02 |
| CN103108649B (zh) | 2016-10-12 |
| US9637730B2 (en) | 2017-05-02 |
| WO2012021249A3 (en) | 2012-04-26 |
| AU2011289833A1 (en) | 2013-02-21 |
| JP6177129B2 (ja) | 2017-08-09 |
| EP2593126B1 (en) | 2017-09-20 |
| KR20130102534A (ko) | 2013-09-17 |
| AU2011289833B2 (en) | 2017-02-02 |
| JP2013533750A (ja) | 2013-08-29 |
| EP2593126A2 (en) | 2013-05-22 |
| US20190264190A1 (en) | 2019-08-29 |
| JP2017201993A (ja) | 2017-11-16 |
| JP2015227379A (ja) | 2015-12-17 |
| CA2804424C (en) | 2021-03-30 |
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