ES2594709T3 - Un proceso de preparación de una sal de amonio cuaternario - Google Patents

Un proceso de preparación de una sal de amonio cuaternario Download PDF

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Publication number
ES2594709T3
ES2594709T3 ES11775164.4T ES11775164T ES2594709T3 ES 2594709 T3 ES2594709 T3 ES 2594709T3 ES 11775164 T ES11775164 T ES 11775164T ES 2594709 T3 ES2594709 T3 ES 2594709T3
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ES
Spain
Prior art keywords
compound
group
formula
methyl
quaternary ammonium
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
ES11775164.4T
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English (en)
Spanish (es)
Inventor
Nobuyuki Ae
Yuji Fujiwara
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sumitomo Pharma Co Ltd
Original Assignee
Sumitomo Dainippon Pharma Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
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Application granted granted Critical
Publication of ES2594709T3 publication Critical patent/ES2594709T3/es
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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/10—Spiro-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • General Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Psychiatry (AREA)
  • Hospice & Palliative Care (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
ES11775164.4T 2010-04-26 2011-04-25 Un proceso de preparación de una sal de amonio cuaternario Active ES2594709T3 (es)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US32780910P 2010-04-26 2010-04-26
US327809P 2010-04-26
PCT/JP2011/060570 WO2011136383A1 (en) 2010-04-26 2011-04-25 A process of a quaternary ammonium salt

Publications (1)

Publication Number Publication Date
ES2594709T3 true ES2594709T3 (es) 2016-12-22

Family

ID=44816340

Family Applications (1)

Application Number Title Priority Date Filing Date
ES11775164.4T Active ES2594709T3 (es) 2010-04-26 2011-04-25 Un proceso de preparación de una sal de amonio cuaternario

Country Status (7)

Country Link
US (2) US8921551B2 (enExample)
EP (1) EP2563790B1 (enExample)
JP (1) JP5820821B2 (enExample)
DK (1) DK2563790T3 (enExample)
ES (1) ES2594709T3 (enExample)
HU (1) HUE030294T2 (enExample)
WO (1) WO2011136383A1 (enExample)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP5820822B2 (ja) 2010-04-26 2015-11-24 大日本住友製薬株式会社 リン酸塩を用いる第四級アンモニウム塩の製造法
WO2013121440A1 (en) 2012-02-13 2013-08-22 Cadila Healthcare Limited Process for preparing benzisothiazol-3-yl-peperazin-l-yl-methyl-cyclo hexyl-methanisoindol-1,3-dione and its intermediates
CN103450172A (zh) * 2012-05-30 2013-12-18 广州药源生物医药科技有限公司 一种抗精神病药物鲁拉西酮的制备方法
CN102863437A (zh) * 2012-09-04 2013-01-09 济南百诺医药科技开发有限公司 一种鲁拉西酮的制备方法
CN102827157A (zh) * 2012-09-20 2012-12-19 北京哈三联科技股份有限公司 一种制备鲁拉西酮的方法
CN102936243B (zh) * 2012-11-16 2015-08-05 上海伯倚化工科技有限公司 一种鲁拉西酮的合成方法
CN103864774B (zh) * 2012-12-14 2016-09-28 成都弘达药业有限公司 一种鲁拉西酮的制备方法
ITMI20130262A1 (it) * 2013-02-22 2014-08-23 Edmond Pharma Srl Procedimento per la preparazione di lurasidone cloridrato
ITMI20131737A1 (it) 2013-10-17 2015-04-18 Procos Spa Processo per la sintesi industriale di lurasidone
HUE052277T2 (hu) 2014-06-16 2021-04-28 Johnson Matthey Plc Eljárások alkilezett arilpiperazin és alkilezett arilpiperidin vegyületek elõállítására, és új intermedierek
US10426770B2 (en) 2014-10-14 2019-10-01 Jubilant Generics Limited Process for the preparation of Lurasidone hydrochloride
EP3242876A4 (en) * 2015-01-08 2019-01-02 Piramal Enterprises Limited An improved process for the preparation of lurasidone and its intermediate
CN113185508A (zh) * 2015-04-21 2021-07-30 上海医药集团股份有限公司 一种制备高纯度高收率鲁拉西酮的方法
CN106946872A (zh) * 2017-03-20 2017-07-14 常州工程职业技术学院 一种制备鲁拉西酮关键中间体的方法
CN113214243A (zh) * 2017-11-28 2021-08-06 常州寅盛药业有限公司 一种盐酸鲁拉西酮的合成方法

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4351939A (en) * 1980-10-16 1982-09-28 Mead Johnson & Company Spiro-quaternary ammonium halides and N-(2-pyrimidinyl)piperazinylalkylazaspiroalkanedione process
JP2800953B2 (ja) * 1990-07-06 1998-09-21 住友製薬株式会社 新規なイミド誘導体
JP3775823B2 (ja) * 1995-06-09 2006-05-17 大日本住友製薬株式会社 新規なイミド誘導体
JP4175800B2 (ja) * 2001-11-27 2008-11-05 住友化学株式会社 イミド誘導体の製造方法
DK1652848T3 (da) 2003-07-29 2012-02-27 Dainippon Sumitomo Pharma Co Fremgangsmåde til fremstilling af imidforbindelse
JP2006169154A (ja) * 2004-12-15 2006-06-29 Sumitomo Chemical Co Ltd 第四級アンモニウム塩の製造方法
JP4708012B2 (ja) * 2004-12-15 2011-06-22 大日本住友製薬株式会社 第四級アンモニウム塩の製造法
CN101300260B (zh) 2005-08-30 2012-05-09 霍尼韦尔国际公司 合成螺环季铵体系的方法
US20110003994A1 (en) * 2009-07-02 2011-01-06 Dainippon Sumitomo Pharma Co., Ltd. Cycloalkane derivative
JP5820822B2 (ja) * 2010-04-26 2015-11-24 大日本住友製薬株式会社 リン酸塩を用いる第四級アンモニウム塩の製造法

Also Published As

Publication number Publication date
EP2563790A1 (en) 2013-03-06
US20110263847A1 (en) 2011-10-27
US8921551B2 (en) 2014-12-30
EP2563790B1 (en) 2016-09-14
JP2013525264A (ja) 2013-06-20
JP5820821B2 (ja) 2015-11-24
EP2563790A4 (en) 2014-02-19
WO2011136383A1 (en) 2011-11-03
HUE030294T2 (en) 2017-04-28
US20150087830A1 (en) 2015-03-26
US9309255B2 (en) 2016-04-12
DK2563790T3 (en) 2016-10-24

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