ES2567296T3 - Procedimiento para usar una cepa de Bacillus subtilis para potenciar la salud animal - Google Patents
Procedimiento para usar una cepa de Bacillus subtilis para potenciar la salud animal Download PDFInfo
- Publication number
- ES2567296T3 ES2567296T3 ES14163676.1T ES14163676T ES2567296T3 ES 2567296 T3 ES2567296 T3 ES 2567296T3 ES 14163676 T ES14163676 T ES 14163676T ES 2567296 T3 ES2567296 T3 ES 2567296T3
- Authority
- ES
- Spain
- Prior art keywords
- bacillus subtilis
- bacillus
- feed
- qst713
- composition
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Active
Links
- 244000063299 Bacillus subtilis Species 0.000 title abstract description 28
- 235000014469 Bacillus subtilis Nutrition 0.000 title abstract description 28
- 241001465754 Metazoa Species 0.000 title abstract description 18
- 238000000034 method Methods 0.000 title abstract description 10
- 230000036541 health Effects 0.000 title abstract description 4
- 239000000203 mixture Substances 0.000 abstract description 44
- 241000238631 Hexapoda Species 0.000 abstract description 3
- 108091028043 Nucleic acid sequence Proteins 0.000 abstract 1
- 241000193830 Bacillus <bacterium> Species 0.000 description 25
- 241000282887 Suidae Species 0.000 description 9
- 238000012360 testing method Methods 0.000 description 9
- 241000193468 Clostridium perfringens Species 0.000 description 8
- 241000287828 Gallus gallus Species 0.000 description 8
- 235000010633 broth Nutrition 0.000 description 8
- 235000005911 diet Nutrition 0.000 description 8
- 230000005764 inhibitory process Effects 0.000 description 8
- 238000011282 treatment Methods 0.000 description 8
- 238000009472 formulation Methods 0.000 description 7
- 239000004615 ingredient Substances 0.000 description 7
- FAPWRFPIFSIZLT-UHFFFAOYSA-M Sodium chloride Chemical compound [Na+].[Cl-] FAPWRFPIFSIZLT-UHFFFAOYSA-M 0.000 description 6
- 238000005054 agglomeration Methods 0.000 description 6
- 230000002776 aggregation Effects 0.000 description 6
- 244000052769 pathogen Species 0.000 description 6
- 241000894006 Bacteria Species 0.000 description 5
- 241000186781 Listeria Species 0.000 description 5
- 235000014590 basal diet Nutrition 0.000 description 5
- 230000037213 diet Effects 0.000 description 5
- 238000000855 fermentation Methods 0.000 description 5
- 230000004151 fermentation Effects 0.000 description 5
- 238000005469 granulation Methods 0.000 description 5
- 230000003179 granulation Effects 0.000 description 5
- 239000008188 pellet Substances 0.000 description 5
- 239000013535 sea water Substances 0.000 description 5
- 241000271566 Aves Species 0.000 description 4
- 241000589875 Campylobacter jejuni Species 0.000 description 4
- 241001112696 Clostridia Species 0.000 description 4
- 235000010469 Glycine max Nutrition 0.000 description 4
- 241000479842 Pella Species 0.000 description 4
- 239000003242 anti bacterial agent Substances 0.000 description 4
- 229940088710 antibiotic agent Drugs 0.000 description 4
- 150000001720 carbohydrates Chemical class 0.000 description 4
- 235000014633 carbohydrates Nutrition 0.000 description 4
- 238000006243 chemical reaction Methods 0.000 description 4
- 244000144977 poultry Species 0.000 description 4
- 235000013594 poultry meat Nutrition 0.000 description 4
- 239000000843 powder Substances 0.000 description 4
- 238000002360 preparation method Methods 0.000 description 4
- 239000006041 probiotic Substances 0.000 description 4
- 235000018291 probiotics Nutrition 0.000 description 4
- 239000000047 product Substances 0.000 description 4
- 235000018102 proteins Nutrition 0.000 description 4
- 108090000623 proteins and genes Proteins 0.000 description 4
- 102000004169 proteins and genes Human genes 0.000 description 4
- 229920001817 Agar Polymers 0.000 description 3
- 208000004232 Enteritis Diseases 0.000 description 3
- 241000588724 Escherichia coli Species 0.000 description 3
- 241000186779 Listeria monocytogenes Species 0.000 description 3
- 241000607142 Salmonella Species 0.000 description 3
- 240000008042 Zea mays Species 0.000 description 3
- 235000005824 Zea mays ssp. parviglumis Nutrition 0.000 description 3
- 235000002017 Zea mays subsp mays Nutrition 0.000 description 3
- 239000008272 agar Substances 0.000 description 3
- 230000001332 colony forming effect Effects 0.000 description 3
- 235000005822 corn Nutrition 0.000 description 3
- 230000000378 dietary effect Effects 0.000 description 3
- 238000001035 drying Methods 0.000 description 3
- 230000000694 effects Effects 0.000 description 3
- 235000013312 flour Nutrition 0.000 description 3
- -1 glucanase Proteins 0.000 description 3
- 238000001727 in vivo Methods 0.000 description 3
- 230000000977 initiatory effect Effects 0.000 description 3
- 239000002207 metabolite Substances 0.000 description 3
- 230000001338 necrotic effect Effects 0.000 description 3
- 235000015097 nutrients Nutrition 0.000 description 3
- 230000001717 pathogenic effect Effects 0.000 description 3
- 239000011780 sodium chloride Substances 0.000 description 3
- 239000010902 straw Substances 0.000 description 3
- 239000000725 suspension Substances 0.000 description 3
- 230000001225 therapeutic effect Effects 0.000 description 3
- 239000003981 vehicle Substances 0.000 description 3
- 235000019786 weight gain Nutrition 0.000 description 3
- 230000004584 weight gain Effects 0.000 description 3
- 239000004382 Amylase Substances 0.000 description 2
- 108010065511 Amylases Proteins 0.000 description 2
- 102000013142 Amylases Human genes 0.000 description 2
- 241000194108 Bacillus licheniformis Species 0.000 description 2
- VTYYLEPIZMXCLO-UHFFFAOYSA-L Calcium carbonate Chemical compound [Ca+2].[O-]C([O-])=O VTYYLEPIZMXCLO-UHFFFAOYSA-L 0.000 description 2
- 229920001202 Inulin Polymers 0.000 description 2
- KDXKERNSBIXSRK-YFKPBYRVSA-N L-lysine Chemical compound NCCCC[C@H](N)C(O)=O KDXKERNSBIXSRK-YFKPBYRVSA-N 0.000 description 2
- DLRVVLDZNNYCBX-UHFFFAOYSA-N Polydextrose Polymers OC1C(O)C(O)C(CO)OC1OCC1C(O)C(O)C(O)C(O)O1 DLRVVLDZNNYCBX-UHFFFAOYSA-N 0.000 description 2
- 241001354013 Salmonella enterica subsp. enterica serovar Enteritidis Species 0.000 description 2
- 235000019418 amylase Nutrition 0.000 description 2
- 238000004458 analytical method Methods 0.000 description 2
- 239000003674 animal food additive Substances 0.000 description 2
- 230000001580 bacterial effect Effects 0.000 description 2
- 244000052616 bacterial pathogen Species 0.000 description 2
- 230000009286 beneficial effect Effects 0.000 description 2
- 238000010790 dilution Methods 0.000 description 2
- 239000012895 dilution Substances 0.000 description 2
- 201000010099 disease Diseases 0.000 description 2
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 2
- 230000007613 environmental effect Effects 0.000 description 2
- 210000003608 fece Anatomy 0.000 description 2
- 230000009036 growth inhibition Effects 0.000 description 2
- 238000010438 heat treatment Methods 0.000 description 2
- 229910052500 inorganic mineral Inorganic materials 0.000 description 2
- JYJIGFIDKWBXDU-MNNPPOADSA-N inulin Chemical compound O[C@H]1[C@H](O)[C@@H](CO)O[C@@]1(CO)OC[C@]1(OC[C@]2(OC[C@]3(OC[C@]4(OC[C@]5(OC[C@]6(OC[C@]7(OC[C@]8(OC[C@]9(OC[C@]%10(OC[C@]%11(OC[C@]%12(OC[C@]%13(OC[C@]%14(OC[C@]%15(OC[C@]%16(OC[C@]%17(OC[C@]%18(OC[C@]%19(OC[C@]%20(OC[C@]%21(OC[C@]%22(OC[C@]%23(OC[C@]%24(OC[C@]%25(OC[C@]%26(OC[C@]%27(OC[C@]%28(OC[C@]%29(OC[C@]%30(OC[C@]%31(OC[C@]%32(OC[C@]%33(OC[C@]%34(OC[C@]%35(OC[C@]%36(O[C@@H]%37[C@@H]([C@@H](O)[C@H](O)[C@@H](CO)O%37)O)[C@H]([C@H](O)[C@@H](CO)O%36)O)[C@H]([C@H](O)[C@@H](CO)O%35)O)[C@H]([C@H](O)[C@@H](CO)O%34)O)[C@H]([C@H](O)[C@@H](CO)O%33)O)[C@H]([C@H](O)[C@@H](CO)O%32)O)[C@H]([C@H](O)[C@@H](CO)O%31)O)[C@H]([C@H](O)[C@@H](CO)O%30)O)[C@H]([C@H](O)[C@@H](CO)O%29)O)[C@H]([C@H](O)[C@@H](CO)O%28)O)[C@H]([C@H](O)[C@@H](CO)O%27)O)[C@H]([C@H](O)[C@@H](CO)O%26)O)[C@H]([C@H](O)[C@@H](CO)O%25)O)[C@H]([C@H](O)[C@@H](CO)O%24)O)[C@H]([C@H](O)[C@@H](CO)O%23)O)[C@H]([C@H](O)[C@@H](CO)O%22)O)[C@H]([C@H](O)[C@@H](CO)O%21)O)[C@H]([C@H](O)[C@@H](CO)O%20)O)[C@H]([C@H](O)[C@@H](CO)O%19)O)[C@H]([C@H](O)[C@@H](CO)O%18)O)[C@H]([C@H](O)[C@@H](CO)O%17)O)[C@H]([C@H](O)[C@@H](CO)O%16)O)[C@H]([C@H](O)[C@@H](CO)O%15)O)[C@H]([C@H](O)[C@@H](CO)O%14)O)[C@H]([C@H](O)[C@@H](CO)O%13)O)[C@H]([C@H](O)[C@@H](CO)O%12)O)[C@H]([C@H](O)[C@@H](CO)O%11)O)[C@H]([C@H](O)[C@@H](CO)O%10)O)[C@H]([C@H](O)[C@@H](CO)O9)O)[C@H]([C@H](O)[C@@H](CO)O8)O)[C@H]([C@H](O)[C@@H](CO)O7)O)[C@H]([C@H](O)[C@@H](CO)O6)O)[C@H]([C@H](O)[C@@H](CO)O5)O)[C@H]([C@H](O)[C@@H](CO)O4)O)[C@H]([C@H](O)[C@@H](CO)O3)O)[C@H]([C@H](O)[C@@H](CO)O2)O)[C@@H](O)[C@H](O)[C@@H](CO)O1 JYJIGFIDKWBXDU-MNNPPOADSA-N 0.000 description 2
- 229940029339 inulin Drugs 0.000 description 2
- 230000003902 lesion Effects 0.000 description 2
- 238000004519 manufacturing process Methods 0.000 description 2
- 239000011707 mineral Substances 0.000 description 2
- 235000010755 mineral Nutrition 0.000 description 2
- 230000009467 reduction Effects 0.000 description 2
- 238000003307 slaughter Methods 0.000 description 2
- 241000894007 species Species 0.000 description 2
- 235000000891 standard diet Nutrition 0.000 description 2
- 230000035899 viability Effects 0.000 description 2
- 239000011782 vitamin Substances 0.000 description 2
- 235000013343 vitamin Nutrition 0.000 description 2
- 229940088594 vitamin Drugs 0.000 description 2
- 229930003231 vitamin Natural products 0.000 description 2
- 238000005406 washing Methods 0.000 description 2
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Chemical compound O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 2
- 241000193749 Bacillus coagulans Species 0.000 description 1
- 241000193422 Bacillus lentus Species 0.000 description 1
- 241000194103 Bacillus pumilus Species 0.000 description 1
- 241000193417 Brevibacillus laterosporus Species 0.000 description 1
- 241001204123 Campylobacter jejuni Cj1 Species 0.000 description 1
- 244000025254 Cannabis sativa Species 0.000 description 1
- 108010059892 Cellulase Proteins 0.000 description 1
- 241000238424 Crustacea Species 0.000 description 1
- 102000004127 Cytokines Human genes 0.000 description 1
- 108090000695 Cytokines Proteins 0.000 description 1
- 239000004470 DL Methionine Substances 0.000 description 1
- 241000238557 Decapoda Species 0.000 description 1
- 101710121765 Endo-1,4-beta-xylanase Proteins 0.000 description 1
- 108090000790 Enzymes Proteins 0.000 description 1
- 102000004190 Enzymes Human genes 0.000 description 1
- 201000000297 Erysipelas Diseases 0.000 description 1
- 241000186810 Erysipelothrix rhusiopathiae Species 0.000 description 1
- 241001333951 Escherichia coli O157 Species 0.000 description 1
- 235000019733 Fish meal Nutrition 0.000 description 1
- RFSUNEUAIZKAJO-ARQDHWQXSA-N Fructose Chemical class OC[C@H]1O[C@](O)(CO)[C@@H](O)[C@@H]1O RFSUNEUAIZKAJO-ARQDHWQXSA-N 0.000 description 1
- 108010073178 Glucan 1,4-alpha-Glucosidase Proteins 0.000 description 1
- 102100022624 Glucoamylase Human genes 0.000 description 1
- 108010068370 Glutens Proteins 0.000 description 1
- 244000068988 Glycine max Species 0.000 description 1
- 102000014150 Interferons Human genes 0.000 description 1
- 108010050904 Interferons Proteins 0.000 description 1
- 102000015696 Interleukins Human genes 0.000 description 1
- 108010063738 Interleukins Proteins 0.000 description 1
- 235000019766 L-Lysine Nutrition 0.000 description 1
- QIVBCDIJIAJPQS-VIFPVBQESA-N L-tryptophane Chemical compound C1=CC=C2C(C[C@H](N)C(O)=O)=CNC2=C1 QIVBCDIJIAJPQS-VIFPVBQESA-N 0.000 description 1
- 235000019738 Limestone Nutrition 0.000 description 1
- 241000186807 Listeria seeligeri Species 0.000 description 1
- 241000186814 Listeria welshimeri Species 0.000 description 1
- 239000004472 Lysine Substances 0.000 description 1
- 240000004658 Medicago sativa Species 0.000 description 1
- 235000017587 Medicago sativa ssp. sativa Nutrition 0.000 description 1
- 208000012868 Overgrowth Diseases 0.000 description 1
- 241001494479 Pecora Species 0.000 description 1
- 229920001100 Polydextrose Polymers 0.000 description 1
- 108010059820 Polygalacturonase Proteins 0.000 description 1
- 240000004808 Saccharomyces cerevisiae Species 0.000 description 1
- 235000014680 Saccharomyces cerevisiae Nutrition 0.000 description 1
- 241000533331 Salmonella bongori Species 0.000 description 1
- 241001138501 Salmonella enterica Species 0.000 description 1
- 241000607356 Salmonella enterica subsp. arizonae Species 0.000 description 1
- 108010046377 Whey Proteins Proteins 0.000 description 1
- 102000007544 Whey Proteins Human genes 0.000 description 1
- 208000027418 Wounds and injury Diseases 0.000 description 1
- 239000002253 acid Substances 0.000 description 1
- 238000003556 assay Methods 0.000 description 1
- 235000021053 average weight gain Nutrition 0.000 description 1
- 229940054340 bacillus coagulans Drugs 0.000 description 1
- 239000008280 blood Substances 0.000 description 1
- 210000004369 blood Anatomy 0.000 description 1
- 230000037396 body weight Effects 0.000 description 1
- YYRMJZQKEFZXMX-UHFFFAOYSA-L calcium bis(dihydrogenphosphate) Chemical compound [Ca+2].OP(O)([O-])=O.OP(O)([O-])=O YYRMJZQKEFZXMX-UHFFFAOYSA-L 0.000 description 1
- 229910000019 calcium carbonate Inorganic materials 0.000 description 1
- 239000001506 calcium phosphate Substances 0.000 description 1
- 229940106157 cellulase Drugs 0.000 description 1
- 235000013339 cereals Nutrition 0.000 description 1
- 239000003224 coccidiostatic agent Substances 0.000 description 1
- 230000002860 competitive effect Effects 0.000 description 1
- 230000006378 damage Effects 0.000 description 1
- 230000003247 decreasing effect Effects 0.000 description 1
- 238000011026 diafiltration Methods 0.000 description 1
- 230000029087 digestion Effects 0.000 description 1
- 239000012470 diluted sample Substances 0.000 description 1
- 239000012153 distilled water Substances 0.000 description 1
- 229940079593 drug Drugs 0.000 description 1
- 239000003814 drug Substances 0.000 description 1
- 235000013601 eggs Nutrition 0.000 description 1
- 230000008030 elimination Effects 0.000 description 1
- 238000003379 elimination reaction Methods 0.000 description 1
- 238000005516 engineering process Methods 0.000 description 1
- 229940088598 enzyme Drugs 0.000 description 1
- 108010093305 exopolygalacturonase Proteins 0.000 description 1
- 238000002474 experimental method Methods 0.000 description 1
- 239000003925 fat Substances 0.000 description 1
- 235000019197 fats Nutrition 0.000 description 1
- 235000021050 feed intake Nutrition 0.000 description 1
- 235000013360 fish flour Nutrition 0.000 description 1
- 239000004467 fishmeal Substances 0.000 description 1
- 235000021255 galacto-oligosaccharides Nutrition 0.000 description 1
- 150000003271 galactooligosaccharides Chemical class 0.000 description 1
- 235000021312 gluten Nutrition 0.000 description 1
- 239000008187 granular material Substances 0.000 description 1
- 239000001963 growth medium Substances 0.000 description 1
- 244000005709 gut microbiome Species 0.000 description 1
- 239000002955 immunomodulating agent Substances 0.000 description 1
- 229940121354 immunomodulator Drugs 0.000 description 1
- 230000006872 improvement Effects 0.000 description 1
- 238000000338 in vitro Methods 0.000 description 1
- 238000001802 infusion Methods 0.000 description 1
- 230000002401 inhibitory effect Effects 0.000 description 1
- 239000003999 initiator Substances 0.000 description 1
- 208000014674 injury Diseases 0.000 description 1
- 238000011081 inoculation Methods 0.000 description 1
- 229940047124 interferons Drugs 0.000 description 1
- 229940047122 interleukins Drugs 0.000 description 1
- 230000000968 intestinal effect Effects 0.000 description 1
- 210000000936 intestine Anatomy 0.000 description 1
- BJHIKXHVCXFQLS-PQLUHFTBSA-N keto-D-tagatose Chemical compound OC[C@@H](O)[C@H](O)[C@H](O)C(=O)CO BJHIKXHVCXFQLS-PQLUHFTBSA-N 0.000 description 1
- 239000006028 limestone Substances 0.000 description 1
- 238000012423 maintenance Methods 0.000 description 1
- 239000000463 material Substances 0.000 description 1
- 235000012054 meals Nutrition 0.000 description 1
- 235000013372 meat Nutrition 0.000 description 1
- 238000002483 medication Methods 0.000 description 1
- 239000002609 medium Substances 0.000 description 1
- FFEARJCKVFRZRR-UHFFFAOYSA-N methionine Chemical compound CSCCC(N)C(O)=O FFEARJCKVFRZRR-UHFFFAOYSA-N 0.000 description 1
- 235000006109 methionine Nutrition 0.000 description 1
- 229930182817 methionine Natural products 0.000 description 1
- 235000013336 milk Nutrition 0.000 description 1
- 239000008267 milk Substances 0.000 description 1
- 210000004080 milk Anatomy 0.000 description 1
- 229910000150 monocalcium phosphate Inorganic materials 0.000 description 1
- 235000019691 monocalcium phosphate Nutrition 0.000 description 1
- 239000006916 nutrient agar Substances 0.000 description 1
- 229920001542 oligosaccharide Polymers 0.000 description 1
- 150000002482 oligosaccharides Chemical class 0.000 description 1
- 239000008363 phosphate buffer Substances 0.000 description 1
- 239000001259 polydextrose Substances 0.000 description 1
- 235000013856 polydextrose Nutrition 0.000 description 1
- 229940035035 polydextrose Drugs 0.000 description 1
- 230000008569 process Effects 0.000 description 1
- 230000002829 reductive effect Effects 0.000 description 1
- 238000011160 research Methods 0.000 description 1
- 230000002441 reversible effect Effects 0.000 description 1
- 150000003839 salts Chemical class 0.000 description 1
- 239000000243 solution Substances 0.000 description 1
- 235000012424 soybean oil Nutrition 0.000 description 1
- 239000003549 soybean oil Substances 0.000 description 1
- 239000007921 spray Substances 0.000 description 1
- 238000010561 standard procedure Methods 0.000 description 1
- 239000011550 stock solution Substances 0.000 description 1
- 239000006228 supernatant Substances 0.000 description 1
- 239000012137 tryptone Substances 0.000 description 1
- 150000003722 vitamin derivatives Chemical class 0.000 description 1
- 235000021119 whey protein Nutrition 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23K—FODDER
- A23K10/00—Animal feeding-stuffs
- A23K10/10—Animal feeding-stuffs obtained by microbiological or biochemical processes
- A23K10/16—Addition of microorganisms or extracts thereof, e.g. single-cell proteins, to feeding-stuff compositions
- A23K10/18—Addition of microorganisms or extracts thereof, e.g. single-cell proteins, to feeding-stuff compositions of live microorganisms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/66—Microorganisms or materials therefrom
- A61K35/74—Bacteria
- A61K35/741—Probiotics
- A61K35/742—Spore-forming bacteria, e.g. Bacillus coagulans, Bacillus subtilis, clostridium or Lactobacillus sporogenes
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23K—FODDER
- A23K50/00—Feeding-stuffs specially adapted for particular animals
- A23K50/10—Feeding-stuffs specially adapted for particular animals for ruminants
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23K—FODDER
- A23K50/00—Feeding-stuffs specially adapted for particular animals
- A23K50/30—Feeding-stuffs specially adapted for particular animals for swines
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23K—FODDER
- A23K50/00—Feeding-stuffs specially adapted for particular animals
- A23K50/70—Feeding-stuffs specially adapted for particular animals for birds
- A23K50/75—Feeding-stuffs specially adapted for particular animals for birds for poultry
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Polymers & Plastics (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Zoology (AREA)
- Microbiology (AREA)
- Food Science & Technology (AREA)
- Animal Husbandry (AREA)
- Birds (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Molecular Biology (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Mycology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Physiology (AREA)
- Biotechnology (AREA)
- Biomedical Technology (AREA)
- Biochemistry (AREA)
- Epidemiology (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Fodder In General (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Feed For Specific Animals (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US192436P | 1998-11-16 | ||
| US19243608P | 2008-09-17 | 2008-09-17 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES2567296T3 true ES2567296T3 (es) | 2016-04-21 |
Family
ID=42039870
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES14163676.1T Active ES2567296T3 (es) | 2008-09-17 | 2009-09-17 | Procedimiento para usar una cepa de Bacillus subtilis para potenciar la salud animal |
| ES09815204.4T Active ES2527673T3 (es) | 2008-09-17 | 2009-09-17 | Procedimiento para usar una cepa de Bacillus subtilis para potenciar la salud animal |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES09815204.4T Active ES2527673T3 (es) | 2008-09-17 | 2009-09-17 | Procedimiento para usar una cepa de Bacillus subtilis para potenciar la salud animal |
Country Status (23)
| Country | Link |
|---|---|
| US (3) | US20100092428A1 (https=) |
| EP (2) | EP2348880B1 (https=) |
| JP (2) | JP6084771B2 (https=) |
| CN (2) | CN102223809A (https=) |
| AR (1) | AR073606A1 (https=) |
| AU (1) | AU2009293213C1 (https=) |
| BR (1) | BRPI0918033A8 (https=) |
| CA (1) | CA2736885C (https=) |
| CL (1) | CL2009001874A1 (https=) |
| CO (1) | CO6361864A2 (https=) |
| CR (1) | CR20110206A (https=) |
| DK (2) | DK2754354T3 (https=) |
| EC (1) | ECSP11010975A (https=) |
| ES (2) | ES2567296T3 (https=) |
| MX (1) | MX2011002889A (https=) |
| NZ (1) | NZ592154A (https=) |
| PE (1) | PE20120074A1 (https=) |
| PH (1) | PH12015501581A1 (https=) |
| PL (1) | PL2348880T3 (https=) |
| RU (1) | RU2544952C2 (https=) |
| TW (1) | TWI574628B (https=) |
| WO (1) | WO2010033714A1 (https=) |
| ZA (1) | ZA201102627B (https=) |
Families Citing this family (80)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DK2754354T3 (en) | 2008-09-17 | 2016-03-21 | Bayer Cropscience Lp | A method of using a Bacillus subtilis strain to improve the animal health |
| EP2547348B1 (en) * | 2010-03-17 | 2015-05-20 | Bayer Cropscience LP | Method for using a bacillus subtilis strain for prophylaxis and treatment of gastro-intestinal conditions |
| WO2012009712A2 (en) * | 2010-07-16 | 2012-01-19 | The Board Of Trustees Of The University Of Arkansas | Methods and compositions including spore-forming bacteria for increasing the health of animals |
| US9107938B2 (en) | 2010-09-30 | 2015-08-18 | The Board Of Trustees Of The University Of Arkansas | Methods of selecting and using therapeutic and prophylactic probiotic cultures to reduce bacterial pathogen loads |
| CA2836131A1 (en) | 2011-05-24 | 2012-11-29 | Bayer Cropscience Lp | Synergistic combinations of polyene fungicides and non-ribosomal peptides and related methods of use |
| RU2014119583A (ru) * | 2011-08-24 | 2015-11-20 | ДЮПОНТ НЬЮТРИШЭН БАЙОСАЙНСИЗ ЭйПиЭс | Штамм бацилл и содержащая его композиция |
| CN102273428B (zh) * | 2011-09-14 | 2013-01-02 | 定边县华威生物科技有限公司 | 一种红蛋黄高蛋白富硒营养鸡蛋生产方法 |
| KR101317549B1 (ko) * | 2011-11-08 | 2013-10-15 | 씨제이제일제당 (주) | 발효 옥수수글루텐의 제조방법 |
| MX2014009103A (es) * | 2012-01-27 | 2015-11-18 | Gfs Corp Aus Pty Ltd | Métodos para producir biosurfactantes. |
| JP6212108B2 (ja) | 2012-04-13 | 2017-10-11 | セーホーエル.ハンセン アクティーゼルスカブ | 大腸菌(E.coli)及びクロストリジウム・パーフリンジェンス(Clostridiumperfringens)に対する抗菌効果を有し、且つ高い胞子形成能を有する抗生物質感受性バチルス株 |
| FR2992861B1 (fr) * | 2012-07-09 | 2014-10-17 | Probionov | Utilisation de thiosulfate pour potentialiser l'effet anti-pathogene des lactobacilles |
| WO2014022572A1 (en) | 2012-08-01 | 2014-02-06 | Pacific Vet Group-Usa, Inc. | Probiotic for amelioration of coccidiosis vaccine reaction |
| RU2015111500A (ru) * | 2012-08-31 | 2016-10-20 | БАЙЕР КРОПСАЙЕНС ЭлПи | Способ повышения устойчивости растения к абиотическому стрессу |
| US11883443B2 (en) * | 2013-04-09 | 2024-01-30 | Novozymes A/S | Compositions and methods for improving the health of aquatic animals |
| WO2014185516A1 (ja) | 2013-05-17 | 2014-11-20 | カルピス株式会社 | 反芻動物の乳房炎の予防または治療剤 |
| CN103555707A (zh) * | 2013-10-28 | 2014-02-05 | 青岛蔚蓝生物集团有限公司 | 一种制备复合菌剂的方法 |
| JP6440463B2 (ja) * | 2013-11-15 | 2018-12-19 | プリマハム株式会社 | 抗菌作用を有するバチルス・メチロトロフィカス |
| CA2948832A1 (en) | 2014-05-13 | 2015-11-19 | Microbial Discovery Group, Llc | Direct-fed microbials and methods of their use |
| CA2954422A1 (en) | 2014-07-29 | 2016-02-04 | BiOWiSH Technologies, Inc. | Animal feed compositions and feed additives |
| WO2016060934A1 (en) | 2014-10-08 | 2016-04-21 | Novozymes A/S | Bacillus strains with fast germination and antimicrobial activity against clostridium perfringens |
| WO2016060935A2 (en) | 2014-10-08 | 2016-04-21 | Novozymes A/S | Compositions and methods of improving the digestibility of animal feed |
| TWI659696B (zh) * | 2014-12-12 | 2019-05-21 | 南京莎菲特生物科技有限公司 | 一種製備含高濃度表面素之飼料添加劑的方法 |
| WO2016118840A1 (en) * | 2015-01-23 | 2016-07-28 | Novozymes A/S | Bacillus strains improving health and performance of production animals |
| EP3261653B1 (en) | 2015-01-23 | 2019-10-09 | Novozymes A/S | Bacillus subtilis subspecies |
| US11166989B2 (en) | 2015-01-23 | 2021-11-09 | Novozymes A/S | Bacillus strains improving health and performance of production animals |
| BR112017019192B1 (pt) * | 2015-03-06 | 2022-09-27 | Norman J. Smallwood | Composição de ração e método de produção de uma composição de ração |
| US10632157B2 (en) | 2016-04-15 | 2020-04-28 | Ascus Biosciences, Inc. | Microbial compositions and methods of use for improving fowl production |
| US10201574B1 (en) | 2015-09-16 | 2019-02-12 | Church & Dwight Co., Inc. | Methods of microbial treatment of poultry |
| WO2017066777A1 (en) * | 2015-10-15 | 2017-04-20 | Kemin Industries, Inc. | Compositions and methods of improving performance and intestinal health of poultry |
| CN108603161B (zh) * | 2015-11-09 | 2021-11-09 | 中国科学院遗传与发育生物学研究所 | 具有有益活性的芽孢杆菌菌株及制剂 |
| US12157690B2 (en) | 2015-12-09 | 2024-12-03 | Microbial Discovery Group Llc | Cold temperature-resistant microbials and methods of their use |
| RU2018130698A (ru) | 2016-01-25 | 2020-02-27 | Новозимс А/С | Способ уменьшения микробного налета в инкубаторе для сельскохозяйственной птицы |
| US10335440B2 (en) | 2016-02-29 | 2019-07-02 | Microbial Discovery Group, Llc | Direct-fed microbials |
| MX391417B (es) | 2016-04-15 | 2025-03-21 | Native Microbials Inc | Métodos para mejorar la producción agrícola de aves de corral mediante la administración de consorcios microbianos o cepas purificadas de los mismos. |
| US11298383B2 (en) | 2016-05-20 | 2022-04-12 | Church & Dwight Co., Inc. | Lactobacillus and bacillus based direct fed microbial treatment for poultry and method of use |
| EP3464648A1 (en) * | 2016-05-25 | 2019-04-10 | Church & Dwight Co., Inc. | Bacillus compositions and methods of use with ruminants |
| CN121713997A (zh) * | 2016-05-26 | 2026-03-24 | 椿产业株式会社 | 乙酰基半胱氨酸作为产卵鸡的产卵数改善剂的用途 |
| US11173184B2 (en) * | 2016-05-31 | 2021-11-16 | Evonik Operations Gmbh | Bacillus subtilis strain with probiotic activity |
| CN106497822A (zh) * | 2016-09-23 | 2017-03-15 | 天津科技大学 | 一种南美白对虾饲用微生物制剂及制备和应用方法 |
| CA2959252C (en) | 2016-10-03 | 2025-06-03 | Bio-Cat, Inc. | Bacillus compositions and uses thereof |
| TW201813514A (zh) * | 2016-10-05 | 2018-04-16 | 林秀霞 | 促進豬隻生長及改善養殖環境汙染的製劑和方法 |
| US11291695B2 (en) * | 2017-03-14 | 2022-04-05 | Chr. Hansen A/S | Bacillus subtilis strains improving animal performance parameters |
| US11446339B2 (en) | 2017-03-31 | 2022-09-20 | Pebble Labs Inc. | System for the biocontrol of white spot syndrome virus (WSSV) in aquaculture |
| AU2018243858A1 (en) | 2017-03-31 | 2019-10-10 | Pebble Labs Usa Inc. | Novel system for the biocontrol of pathogens in aquaculture and other animal systems |
| WO2019002471A1 (en) * | 2017-06-30 | 2019-01-03 | Evonik Degussa Gmbh | DEBACILLUS SUBTILIS STRAIN HAVING PROBIOTIC ACTIVITY |
| US11622569B2 (en) | 2017-07-24 | 2023-04-11 | Church & Dwight Co., Inc. | Bacillus microbial terroir for pathogen control in swine |
| WO2019032629A1 (en) | 2017-08-07 | 2019-02-14 | Pebble Labs Inc. | SYSTEMS AND METHODS FOR FIGHTING ACUTE HEEPATOPANCREATIC NECROSIS DISEASE |
| CA3073449A1 (en) | 2017-09-25 | 2019-03-28 | Agrospheres, Inc. | Compositions and methods for scalable production and delivery of biologicals |
| US12194142B2 (en) | 2017-09-25 | 2025-01-14 | Deerland Enzymes, Inc. | Bacillus subtilis containing composition for treatment of gastrointestinal irregularity |
| UY37939A (es) * | 2017-10-18 | 2019-04-30 | Ascus Biosciences Inc | Aumento de la producción de aves de corral mediante la administración de un bioensamblaje sintético de microbios o cepas purificadas de los mismos |
| WO2019147799A1 (en) * | 2018-01-24 | 2019-08-01 | Omnigen Research, Llc | Bacillus combination for administration to animals |
| RU2020128159A (ru) | 2018-02-02 | 2022-03-02 | Новозимс А/С | Контроль патогенной lawsonia |
| EP3764807A4 (en) | 2018-03-14 | 2021-11-03 | Sustainable Community Development, LLC | PROBIOTIC AND FOOD ADDITIVE COMPOSITION |
| US20190289878A1 (en) * | 2018-03-23 | 2019-09-26 | Purina Animal Nutrition Llc | Methods of feeding animals feed products containing direct-fed microbials |
| CN112739358B (zh) * | 2018-05-01 | 2024-12-24 | 微生物发现集团有限责任公司 | 用于喂饲的微生物 |
| WO2020065025A1 (en) | 2018-09-28 | 2020-04-02 | Bayer Aktiengesellschaft | Combination of bacterial biological control agent and fatty acids |
| CN112911943A (zh) * | 2018-09-28 | 2021-06-04 | 轨迹Ip有限责任公司 | 用于饲养驯化动物的组合物和方法 |
| WO2020069255A1 (en) | 2018-09-28 | 2020-04-02 | Microbial Discovery Group, Llc | Microorganisms for plant pathogen inhibition |
| CA3115144A1 (en) * | 2018-10-02 | 2020-04-09 | Microbial Discovery Group, Llc | Microbials for animals |
| WO2020084565A2 (en) * | 2018-10-24 | 2020-04-30 | Ciimar - Centro Interdisciplinar De Investigação Marinha E Ambiental | Sporeforming probiotic strains, methods and uses thereof |
| CN109287890B (zh) * | 2018-11-16 | 2022-04-19 | 青岛贝宝海洋科技有限公司 | 含萌发剂的水产养殖用凝结芽孢杆菌饲料添加剂及其制备方法 |
| CN113330107A (zh) * | 2019-01-10 | 2021-08-31 | 赢创运营有限公司 | 发酵液及其用途 |
| KR20220000398A (ko) | 2019-04-12 | 2022-01-03 | 로커스 아이피 컴퍼니 엘엘씨 | 향상된 탄소 격리 및 가축 생산 온실 가스 배출 감소를 위한 목초지 처리 |
| US11160838B2 (en) | 2019-08-09 | 2021-11-02 | Deerland Enzymes, Inc. | Antifungal and antimicrobial uses of Bacillus subtilis containing compositions |
| BR112022003209A8 (pt) | 2019-08-22 | 2024-02-06 | Microbial Discovery Group Llc | Método de alimentação de um animal, embalagem comercial, aditivo alimentar para uma ração animal, aditivo para a água potável de um animal, composição alimentar para animal, e uso de um aditivo compreendendo uma cepa de bacillus isolada |
| KR102393430B1 (ko) * | 2019-10-18 | 2022-05-02 | (주)에이티바이오 | 프로바이오틱스를 활용한 사료 및 그 제조방법 |
| FR3110344B1 (fr) * | 2020-05-20 | 2023-12-15 | Nolivade | Procédé de décontamination |
| CN111607541B (zh) * | 2020-06-09 | 2022-09-16 | 中国水产科学研究院黑龙江水产研究所 | 一种虹鳟源枯草芽孢杆菌菌株及其筛选方法和应用 |
| WO2022040279A1 (en) | 2020-08-21 | 2022-02-24 | Microbial Discovery Group, Llc | Microbial strains and antibiotics |
| CA3192065A1 (en) | 2020-08-21 | 2022-02-24 | Microbial Discovery Group, Llc | Microbials and antibiotics |
| US20240000865A1 (en) * | 2020-11-23 | 2024-01-04 | Univerza V Ljuubljani | Bacillus subtilis strain with strong inhibition of enteropathogenic and foodborne pathogenic bacteria |
| EP4258875A4 (en) * | 2020-12-09 | 2024-11-20 | Purina Animal Nutrition LLC | Feed compositions and methods for inhibiting focal ulcerative dermatitis |
| BR112023012862A2 (pt) * | 2020-12-25 | 2023-11-28 | Hayashibara Co | Método para melhorar a produtividade de gado e/ou aves domésticos e método para melhorar a flora intestinal de gado e/ou aves domésticos |
| CN112890014B (zh) * | 2021-01-29 | 2024-01-23 | 河南科技大学 | 采用复合益生菌发酵浓香型酒糟生产抗生素代替剂的方法 |
| WO2023220288A1 (en) * | 2022-05-12 | 2023-11-16 | Can Technologies, Inc. | Feed additive compositions comprising microbial fermentate for the treatment and prevention of pathogen associated disease |
| BR102022011914A2 (pt) | 2022-06-15 | 2022-07-26 | Total Biotecnologia Ind E Comercio S/A | Composição probiótica líquida para maior tolerância ao estresse térmico em aves, método de produção da composição e uso da mesma no tratamento das aves |
| CA3260270A1 (en) * | 2022-06-22 | 2023-12-28 | Iowa State University Research Foundation, Inc. | FIGHTING HISTAMINE TO PROMOTE HEALTH AND COMBAT ENTEROCOLITIS WITH PROBIOTIC COMPOUNDS |
| EP4599045A2 (en) * | 2022-10-05 | 2025-08-13 | Microbial Discovery Group, LLC | Microbial strain compositions |
| CN117903973B (zh) * | 2023-12-22 | 2024-08-30 | 江苏月鹏科技集团有限公司 | 一株枯草芽孢杆菌及其菌剂、发酵饲料和预混料 |
| WO2026012287A2 (en) * | 2024-07-09 | 2026-01-15 | Novozymes A/S | Bacillus strains for animal feed |
Family Cites Families (32)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US508080A (en) * | 1893-11-07 | Autographic register | ||
| DE3067173D1 (en) | 1979-10-19 | 1984-04-26 | Ici Plc | Process for the production of anti-static thermoplastics films and the films thereby produced |
| JPS62232343A (ja) * | 1986-04-01 | 1987-10-12 | Kyodo Shiryo Kk | 幼豚用配合飼料 |
| JPS63209580A (ja) * | 1987-02-25 | 1988-08-31 | Karupisu Shokuhin Kogyo Kk | バチルス・ズブチリスc−3102 |
| KR930001383B1 (ko) | 1990-10-31 | 1993-02-27 | 재단법인 한국화학연구소 | 신규의 바실러스 서브틸리스 아종 및 이로부터 생산되는 항진균 물질 krf-001 복합체의 용도 |
| JPH0754041A (ja) * | 1993-08-13 | 1995-02-28 | Sumitomo Metal Ind Ltd | 冷間鍛造用鋼の製造方法 |
| US5785990A (en) * | 1995-07-10 | 1998-07-28 | Merrick's, Inc. | Feed fortifier and enhancer for preruminant calves and method of using same |
| JP2979294B2 (ja) * | 1996-10-02 | 1999-11-15 | カルピス株式会社 | 鳥類卵殻強度増強剤 |
| PL198772B1 (pl) | 1997-05-09 | 2008-07-31 | Agraquest | Biologicznie czysta kultura Bacillus subtilis, jej metabolit i supernatant z hodowli szczepu, kompozycje do ochrony roślin i owoców przed szkodnikami, sposób ochrony lub leczenia roślin i owoców, agrastatyny, sposób izolowania supernatantu o aktywności owadobójczej |
| US6103228A (en) * | 1997-05-09 | 2000-08-15 | Agraquest, Inc. | Compositions and methods for controlling plant pests |
| US6015553A (en) * | 1997-08-22 | 2000-01-18 | Agraquest, Inc. | Bacillus subtilis strain for controlling insect and nematode pests |
| JP3260111B2 (ja) * | 1997-10-09 | 2002-02-25 | 伊藤忠飼料株式会社 | 鳥類の給餌中止時の体重減少抑制方法及び腸内有害細菌減少方法 |
| US6461607B1 (en) * | 1998-08-24 | 2002-10-08 | Ganeden Biotech, Inc. | Probiotic, lactic acid-producing bacteria and uses thereof |
| JP2000166583A (ja) | 1998-10-02 | 2000-06-20 | Shin Nihonsha:Kk | 枯草菌等が産生する無機物及びその酸塩と副産物及びその誘導体 |
| US6849256B1 (en) | 1999-11-08 | 2005-02-01 | Ganeden Biotech Incorporated | Inhibition of pathogens by probiotic bacteria |
| GB0124580D0 (en) * | 2001-10-12 | 2001-12-05 | Univ Reading | New composition |
| GB0130789D0 (en) * | 2001-12-21 | 2002-02-06 | King S College London | Application of spores |
| AR040927A1 (es) * | 2002-04-10 | 2005-04-27 | Cooperativas Argentinas Cooper | Alimento para la crianza de vacunos neonatos y procedimiento de utilizacion. |
| AT413191B (de) * | 2002-10-11 | 2005-12-15 | Erber Ag | Futtermittel- und/oder trinkwasserzusatz für nutztiere |
| US7247299B2 (en) | 2002-11-27 | 2007-07-24 | Kemin Industries, Inc. | Antimicrobial compounds from Bacillus subtilis for use against animal and human pathogens |
| EP1472933A1 (en) * | 2003-05-01 | 2004-11-03 | Chr. Hansen A/S | Improving health and/or nutritional status of an aquatic animal by aid of Bacillus licheniformis |
| WO2005010052A2 (en) * | 2003-07-24 | 2005-02-03 | Cargill, Incorporated | Enhanced steep-water |
| RU2266747C1 (ru) * | 2004-03-22 | 2005-12-27 | Кубанский государственный аграрный университет | Пробиотическая композиция для животных и птицы |
| KR100587447B1 (ko) * | 2004-03-24 | 2006-06-12 | 한국화학연구원 | 바실러스 서브틸리스 eb120 균주, 이를 포함하는 식물병 방제용 미생물 제제 및 이를 이용하여 식물병을 방제하는방법 |
| US20080057047A1 (en) * | 2005-11-29 | 2008-03-06 | Benedikt Sas | Use of bacillus amyloliquefaciens PB6 for the prophylaxis or treatment of gastrointestinal and immuno-related diseases |
| US7754469B2 (en) | 2005-11-30 | 2010-07-13 | Agtech Products, Inc | Microorganisms and methods for treating poultry |
| JP4968816B2 (ja) | 2006-03-08 | 2012-07-04 | 日本曹達株式会社 | バチルス属細菌の芽胞形成方法 |
| WO2007150052A1 (en) | 2006-06-23 | 2007-12-27 | Equine Research Associates, Ltd | Animal nutritional supplement and method |
| EA020203B1 (ru) | 2007-09-20 | 2014-09-30 | Басф Се | Композиции и агенты, содержащие фунгицидный штамм и активное соединение |
| DK2754354T3 (en) | 2008-09-17 | 2016-03-21 | Bayer Cropscience Lp | A method of using a Bacillus subtilis strain to improve the animal health |
| US8227235B2 (en) * | 2008-12-10 | 2012-07-24 | Alpharma, Llc | Compositions and methods for controlling diseases in animals |
| EP2547348B1 (en) | 2010-03-17 | 2015-05-20 | Bayer Cropscience LP | Method for using a bacillus subtilis strain for prophylaxis and treatment of gastro-intestinal conditions |
-
2009
- 2009-09-17 DK DK14163676.1T patent/DK2754354T3/en active
- 2009-09-17 RU RU2011114988/10A patent/RU2544952C2/ru active
- 2009-09-17 BR BRPI0918033A patent/BRPI0918033A8/pt not_active IP Right Cessation
- 2009-09-17 DK DK09815204.4T patent/DK2348880T3/en active
- 2009-09-17 EP EP09815204.4A patent/EP2348880B1/en active Active
- 2009-09-17 CA CA2736885A patent/CA2736885C/en not_active Expired - Fee Related
- 2009-09-17 AU AU2009293213A patent/AU2009293213C1/en not_active Ceased
- 2009-09-17 WO PCT/US2009/057335 patent/WO2010033714A1/en not_active Ceased
- 2009-09-17 PE PE2011000629A patent/PE20120074A1/es active IP Right Grant
- 2009-09-17 AR ARP090103581A patent/AR073606A1/es active IP Right Grant
- 2009-09-17 PL PL09815204T patent/PL2348880T3/pl unknown
- 2009-09-17 ES ES14163676.1T patent/ES2567296T3/es active Active
- 2009-09-17 CN CN2009801362774A patent/CN102223809A/zh active Pending
- 2009-09-17 TW TW098131404A patent/TWI574628B/zh not_active IP Right Cessation
- 2009-09-17 JP JP2011527073A patent/JP6084771B2/ja not_active Expired - Fee Related
- 2009-09-17 EP EP14163676.1A patent/EP2754354B1/en not_active Not-in-force
- 2009-09-17 NZ NZ592154A patent/NZ592154A/xx not_active IP Right Cessation
- 2009-09-17 CL CL2009001874A patent/CL2009001874A1/es unknown
- 2009-09-17 US US12/561,623 patent/US20100092428A1/en not_active Abandoned
- 2009-09-17 MX MX2011002889A patent/MX2011002889A/es active IP Right Grant
- 2009-09-17 ES ES09815204.4T patent/ES2527673T3/es active Active
- 2009-09-17 CN CN201610875499.XA patent/CN107047934A/zh active Pending
-
2011
- 2011-04-05 CO CO11041787A patent/CO6361864A2/es active IP Right Grant
- 2011-04-08 ZA ZA2011/02627A patent/ZA201102627B/en unknown
- 2011-04-12 EC EC2011010975A patent/ECSP11010975A/es unknown
- 2011-04-25 CR CR20110206A patent/CR20110206A/es unknown
-
2012
- 2012-08-24 US US13/594,051 patent/US9247757B2/en not_active Expired - Fee Related
-
2015
- 2015-06-03 JP JP2015112806A patent/JP6106211B2/ja not_active Expired - Fee Related
- 2015-07-16 PH PH12015501581A patent/PH12015501581A1/en unknown
- 2015-12-16 US US14/970,796 patent/US20160100607A1/en not_active Abandoned
Also Published As
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| ES2567296T3 (es) | Procedimiento para usar una cepa de Bacillus subtilis para potenciar la salud animal | |
| JP2021141899A (ja) | 飼料添加用組成物 | |
| Gupta et al. | Growth performance, feed utilization, digestive enzyme activity, innate immunity and protection against Vibrio harveyi of freshwater prawn, Macrobrachium rosenbergii fed diets supplemented with Bacillus coagulans | |
| ES2929354T3 (es) | Lactobacillus plantarum CJLP17 con eficacia antiviral e inmunomoduladora y composición que comprende el mismo | |
| JP2023510910A (ja) | 望ましくない微生物を制御し動物の健康状態を改善するための組成物及び方法 | |
| WO2014151837A1 (en) | A bacillus subtilis strain for use in maintaining or improving the paw health of poultry | |
| JP2025520641A (ja) | 飼料効率を改善するための乳酸菌の使用 | |
| JP7510360B2 (ja) | 死滅したまたは不活化されたメタノブレビバクター古細菌(Methanobrevibacter Archaebacteria)細胞を含む組成物を調製するための方法およびそれによって得られる組成物 | |
| KR20240121790A (ko) | 메탄 생성 미생물 성장 억제 또는 메탄 배출 감소를 위한 유산균의 이용 | |
| KR100857771B1 (ko) | 바실러스 폴리퍼멘티쿠스, 바실러스 리케니포르미스 및사카로마이세스 세르비지에를 포함하는 어류사료첨가용조성물 | |
| Zábranský et al. | Influence of selected feed supplements on the growth and health of calves depending on the sex, season of birth, and number of the dam’s lactations | |
| RU2326692C2 (ru) | Пробиотическое лекарственное средство для сельскохозяйственных животных и птицы | |
| Prabakar et al. | Supplementation of freeze dried Bacillus subtilis QST 713 on growth performance and carcass characteristics in Japanese quail | |
| CA2828541C (en) | Sporulation-deficient b. texasporus cells and methods for efficient and cost-effective inactivation and use thereof | |
| Luka et al. | 16 Role of Probiotics to Control | |
| Luka et al. | Role of Probiotics to Control the Gut-Related Diseases in Terrestrial and Aquatic Animals | |
| KR20260060294A (ko) | 동물 성능 파라미터를 개선하는 바실러스 푸밀루스 균주 | |
| Nyachoti et al. | Canadian Alternatives for Dietary Antibiotics as Growth Promotants | |
| CN120201931A (zh) | 使用凝结芽孢杆菌的直接饲喂的微生物 | |
| UA141243U (uk) | Спосіб підвищення стійкості організму качок до дії технологічного стресу в умовах промислового вирощування |