ES2546360T3 - Modulación antisentido de la expresión de la apolipoproteína B - Google Patents
Modulación antisentido de la expresión de la apolipoproteína B Download PDFInfo
- Publication number
- ES2546360T3 ES2546360T3 ES09015376.8T ES09015376T ES2546360T3 ES 2546360 T3 ES2546360 T3 ES 2546360T3 ES 09015376 T ES09015376 T ES 09015376T ES 2546360 T3 ES2546360 T3 ES 2546360T3
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- Prior art keywords
- apolipoprotein
- animal
- oligonucleotide
- acid
- treatment
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- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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| US13598502A | 2002-04-30 | 2002-04-30 | |
| US10/147,196 US7407943B2 (en) | 2001-08-01 | 2002-05-15 | Antisense modulation of apolipoprotein B expression |
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| US7888324B2 (en) * | 2001-08-01 | 2011-02-15 | Genzyme Corporation | Antisense modulation of apolipoprotein B expression |
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| DK2336318T3 (da) * | 2002-11-13 | 2013-07-15 | Genzyme Corp | Antisense-modulering af apolipoprotein b-ekspression |
| EP1569695B1 (en) * | 2002-11-13 | 2013-05-15 | Genzyme Corporation | Antisense modulation of apolipoprotein b expression |
| US7511131B2 (en) * | 2002-11-13 | 2009-03-31 | Genzyme Corporation | Antisense modulation of apolipoprotein B expression |
| US20060009410A1 (en) * | 2002-11-13 | 2006-01-12 | Crooke Rosanne M | Effects of apolipoprotein B inhibition on gene expression profiles in animals |
| DK2752488T3 (da) | 2002-11-18 | 2020-04-20 | Roche Innovation Ct Copenhagen As | Antisense-design |
| EP3450559A1 (en) | 2003-03-07 | 2019-03-06 | Alnylam Pharmaceuticals, Inc. | Therapeutic compositions |
| JP4912873B2 (ja) * | 2003-04-09 | 2012-04-11 | アルナイラム ファーマシューティカルズ， インコーポレイテッド | ｉＲＮＡ複合体 |
| EP1615611B1 (en) * | 2003-04-09 | 2013-02-13 | Alnylam Pharmaceuticals Inc. | iRNA CONJUGATES |
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- 2002-07-30 EP EP20100180469 patent/EP2336145A1/en not_active Withdrawn
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- 2002-07-30 DK DK09015376.8T patent/DK2174945T3/en active
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- 2002-07-30 EP EP20090015376 patent/EP2174945B1/en not_active Expired - Lifetime
- 2002-07-30 PT PT90153768T patent/PT2174945E/pt unknown
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Also Published As
| Publication number | Publication date |
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| US7407943B2 (en) | 2008-08-05 |
| CA2455228A1 (en) | 2003-02-13 |
| JP2015198669A (ja) | 2015-11-12 |
| DK2174945T3 (en) | 2015-05-26 |
| JP2013066480A (ja) | 2013-04-18 |
| EP2174945A1 (en) | 2010-04-14 |
| PT2174945E (pt) | 2015-06-25 |
| EP1419168A2 (en) | 2004-05-19 |
| US20030215943A1 (en) | 2003-11-20 |
| WO2003011887A2 (en) | 2003-02-13 |
| US20080242629A1 (en) | 2008-10-02 |
| JP2017127311A (ja) | 2017-07-27 |
| EP1419168A4 (en) | 2006-11-15 |
| US20150105440A1 (en) | 2015-04-16 |
| JP2009055925A (ja) | 2009-03-19 |
| JP5797875B2 (ja) | 2015-10-21 |
| WO2003011887A3 (en) | 2003-04-24 |
| JP4471650B2 (ja) | 2010-06-02 |
| JP2005503142A (ja) | 2005-02-03 |
| EP2174945B1 (en) | 2015-04-08 |
| AU2002326481B2 (en) | 2008-11-13 |
| CY1116385T1 (el) | 2017-02-08 |
| US8735364B2 (en) | 2014-05-27 |
| EP2336145A1 (en) | 2011-06-22 |
| US20170355986A1 (en) | 2017-12-14 |
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