ES2536206T3 - Parche medicinal - Google Patents
Parche medicinal Download PDFInfo
- Publication number
- ES2536206T3 ES2536206T3 ES09715573.3T ES09715573T ES2536206T3 ES 2536206 T3 ES2536206 T3 ES 2536206T3 ES 09715573 T ES09715573 T ES 09715573T ES 2536206 T3 ES2536206 T3 ES 2536206T3
- Authority
- ES
- Spain
- Prior art keywords
- agent
- free base
- pharmaceutical agent
- varenicline
- solubilizer
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Active
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/4985—Pyrazines or piperazines ortho- or peri-condensed with heterocyclic ring systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
- A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
- A61K9/703—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
- A61K9/7038—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer
- A61K9/7046—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds
- A61K9/7053—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds obtained by reactions only involving carbon to carbon unsaturated bonds, e.g. polyvinyl, polyisobutylene, polystyrene
- A61K9/7061—Polyacrylates
Landscapes
- Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Dermatology (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
Parche medicinal que comprende como agente farmaceutico vareniclina en su forma de base libre, un material de base adhesivo, un agente de pegajosidad, un solubilizante y una sal de metal, en el que vareniclina en su forma de base libre y la sal de metal pueden obtenerse mediante reaccion de neutralizacion entre la sal de adicion de acido del agente farmaceutico e hidroxido de metal, que se anade en una cantidad para convertir la totalidad o una parte del agente farmaceutico en la base libre, el material de base adhesivo es un material de base adhesivo de caucho y el agente de pegajosidad es un agente de pegajosidad no basado en colofonia seleccionado del grupo que consiste en resinas de hidrocarburo alifatico y resinas de hidrocarburo aliciclico, y el solubilizante se selecciona del grupo que consiste en propilenglicol y dipropilenglicol.
Description
Claims (1)
-
imagen1
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP2008046804 | 2008-02-27 | ||
JP2008046804 | 2008-02-27 | ||
PCT/JP2009/052177 WO2009107477A1 (ja) | 2008-02-27 | 2009-02-09 | 貼付製剤 |
Publications (1)
Publication Number | Publication Date |
---|---|
ES2536206T3 true ES2536206T3 (es) | 2015-05-21 |
Family
ID=41015879
Family Applications (3)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES09715573.3T Active ES2536206T3 (es) | 2008-02-27 | 2009-02-09 | Parche medicinal |
ES09715635.0T Active ES2648197T3 (es) | 2008-02-27 | 2009-02-09 | Parche medicado |
ES09715476T Active ES2778724T3 (es) | 2008-02-27 | 2009-02-09 | Parche |
Family Applications After (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES09715635.0T Active ES2648197T3 (es) | 2008-02-27 | 2009-02-09 | Parche medicado |
ES09715476T Active ES2778724T3 (es) | 2008-02-27 | 2009-02-09 | Parche |
Country Status (5)
Country | Link |
---|---|
US (3) | US8580281B2 (es) |
EP (3) | EP2255809B1 (es) |
JP (3) | JP5537412B2 (es) |
ES (3) | ES2536206T3 (es) |
WO (3) | WO2009107477A1 (es) |
Families Citing this family (39)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US9238025B2 (en) | 2009-05-21 | 2016-01-19 | Hisamitsu Pharmaceutical Co., Inc. | Transdermal preparation comprising a ropinirole derivative |
JP2011074035A (ja) * | 2009-09-30 | 2011-04-14 | Sekisui Medical Co Ltd | 貼付剤 |
JP5615899B2 (ja) * | 2010-02-24 | 2014-10-29 | 久光製薬株式会社 | 経皮吸収製剤 |
US9370495B2 (en) * | 2010-02-24 | 2016-06-21 | Hisamitsu Pharmaceutical Co., Inc. | Adhesive patch |
JP5665330B2 (ja) * | 2010-02-24 | 2015-02-04 | 久光製薬株式会社 | ニコランジル分解抑制剤、経皮吸収製剤及び貼付剤 |
JP5623102B2 (ja) * | 2010-03-12 | 2014-11-12 | 株式会社フジモト・コーポレーション | セレギリン含有貼付製剤 |
JPWO2011118683A1 (ja) * | 2010-03-25 | 2013-07-04 | 東洋化学株式会社 | 医用貼付剤 |
KR20120137373A (ko) | 2010-04-30 | 2012-12-20 | 테이코쿠 팔마 유에스에이, 인코포레이티드 | 프로필아미노인단 경피 조성물 |
WO2011140431A1 (en) * | 2010-05-06 | 2011-11-10 | Teva Pharmaceutical Industries Ltd. | Varenicline salts and crystal forms thereof |
JP5906302B2 (ja) | 2011-03-24 | 2016-04-20 | テイコク ファーマ ユーエスエー インコーポレーテッド | 作用剤層および作用剤変換層を含む経皮組成物 |
WO2012165253A1 (ja) * | 2011-05-31 | 2012-12-06 | 久光製薬株式会社 | ロピニロール含有貼付剤及びその包装体 |
US9918945B2 (en) | 2011-05-31 | 2018-03-20 | Hisamitsu Pharmaceutical Co., Inc. | Ropinirole-containing patch and package thereof |
US8900626B2 (en) | 2011-06-20 | 2014-12-02 | Senju Usa, Inc. | Transdermal drug delivery system and method of using the same |
JP6005742B2 (ja) | 2012-07-26 | 2016-10-12 | 久光製薬株式会社 | 貼付剤 |
US11123305B2 (en) | 2012-07-26 | 2021-09-21 | Hisamitsu Pharmaceutical Co., Inc. | Patch |
CN104797245B (zh) | 2012-11-02 | 2018-05-04 | 帝国制药美国公司 | 丙炔基氨基茚满透皮组合物 |
NZ712334A (en) | 2013-03-15 | 2021-07-30 | Elixirgen Therapeutics Inc | Methods of using zscan4 for rejuvenating human cells |
JP5415645B1 (ja) | 2013-06-28 | 2014-02-12 | 久光製薬株式会社 | 貼付剤の製造方法、貼付剤及び包装体 |
US20160199315A1 (en) * | 2013-08-23 | 2016-07-14 | Hisamitsu Pharmaceutical Co., Inc. | Adhesive patch |
US9980920B2 (en) * | 2013-09-11 | 2018-05-29 | Medrx Co., Ltd. | Base composition for tape agent |
JP6100150B2 (ja) * | 2013-12-06 | 2017-03-22 | 久光製薬株式会社 | 4−アミノピリジン含有貼付剤 |
JP2016079102A (ja) * | 2014-10-10 | 2016-05-16 | テバ製薬株式会社 | ソリフェナシン含有製剤 |
CN104636140B (zh) * | 2015-01-29 | 2018-05-29 | 小米科技有限责任公司 | 固件压缩方法、固件解压方法和装置 |
EP3329914A4 (en) * | 2015-07-27 | 2019-04-03 | Hisamitsu Pharmaceutical Co., Inc. | METHOD FOR MANUFACTURING A STAMPER CONTAINING ASENAPINE |
CN107427509B (zh) * | 2015-08-29 | 2021-06-15 | 美德阿利克斯株式会社 | 含有碱性药物和山梨酸的经皮吸收组成物 |
US10016502B2 (en) | 2015-08-29 | 2018-07-10 | Medrx Co., Ltd | Patch preparation containing an acid scavenger |
US9974858B2 (en) | 2015-08-29 | 2018-05-22 | Medrx Co., Ltd | Percutaneous absorption composition |
WO2017037812A1 (ja) * | 2015-08-29 | 2017-03-09 | 株式会社メドレックス | 酸捕捉剤を含有する貼付製剤 |
CA3047354A1 (en) | 2016-12-20 | 2018-06-28 | Lts Lohmann Therapie-Systeme Ag | Transdermal therapeutic system containing asenapine and polysiloxane or polyisobutylene |
US20180193283A1 (en) | 2016-12-20 | 2018-07-12 | Lts Lohmann Therapie-Systeme Ag | Transdermal therapeutic system containing asenapine |
WO2018155390A1 (ja) | 2017-02-24 | 2018-08-30 | 久光製薬株式会社 | 貼付剤及びその包装体 |
WO2019002204A1 (en) | 2017-06-26 | 2019-01-03 | Lts Lohmann Therapie-Systeme Ag | TRANSDERMAL THERAPEUTIC SYSTEM CONTAINING ASENAPINE AND SILICONE-TYPE ACRYLIC HYBRID POLYMER |
DE102017115701B4 (de) * | 2017-07-12 | 2022-03-03 | Lts Lohmann Therapie-Systeme Ag | Fampridin-TTS |
BR112020026099A2 (pt) | 2018-06-20 | 2021-03-23 | Lts Lohmann Therapie-Systeme Ag | sistema terapêutico transdérmico que contém asenapina |
JP7201389B2 (ja) * | 2018-07-20 | 2023-01-10 | プロクラフト、ディベロップメント、ベスローテン、フェンノートシャップ | 多層生成物を製造する方法 |
US10919288B2 (en) * | 2018-07-20 | 2021-02-16 | Procraft Development Bv | Method of producing a multilayered product |
CN114641286A (zh) | 2019-09-18 | 2022-06-17 | 久光制药株式会社 | 含有罗匹尼罗的贴附剂及罗匹尼罗的皮肤透过性提升方法 |
CN116322658A (zh) | 2020-10-29 | 2023-06-23 | 久光制药株式会社 | 含罗匹尼罗的贴附剂及罗匹尼罗的皮肤透过性的提升方法 |
JP7385614B2 (ja) | 2021-03-10 | 2023-11-22 | 積水化学工業株式会社 | 貼付製剤 |
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-
2009
- 2009-02-09 US US12/919,723 patent/US8580281B2/en active Active
- 2009-02-09 ES ES09715573.3T patent/ES2536206T3/es active Active
- 2009-02-09 WO PCT/JP2009/052177 patent/WO2009107477A1/ja active Application Filing
- 2009-02-09 US US12/919,715 patent/US8871249B2/en active Active
- 2009-02-09 EP EP09715635.0A patent/EP2255809B1/en active Active
- 2009-02-09 EP EP09715476.9A patent/EP2258355B1/en active Active
- 2009-02-09 ES ES09715635.0T patent/ES2648197T3/es active Active
- 2009-02-09 JP JP2010500638A patent/JP5537412B2/ja active Active
- 2009-02-09 US US12/919,739 patent/US20110028880A1/en not_active Abandoned
- 2009-02-09 JP JP2010500637A patent/JP5485135B2/ja active Active
- 2009-02-09 EP EP09715573.3A patent/EP2258369B1/en active Active
- 2009-02-09 JP JP2010500640A patent/JP6054013B2/ja active Active
- 2009-02-09 WO PCT/JP2009/052181 patent/WO2009107479A1/ja active Application Filing
- 2009-02-09 ES ES09715476T patent/ES2778724T3/es active Active
- 2009-02-09 WO PCT/JP2009/052175 patent/WO2009107476A1/ja active Application Filing
Also Published As
Publication number | Publication date |
---|---|
ES2648197T3 (es) | 2017-12-29 |
JP5485135B2 (ja) | 2014-05-07 |
EP2258369A4 (en) | 2011-05-04 |
JP6054013B2 (ja) | 2016-12-27 |
EP2258369B1 (en) | 2015-04-08 |
EP2258369A1 (en) | 2010-12-08 |
EP2255809A4 (en) | 2011-05-04 |
WO2009107479A1 (ja) | 2009-09-03 |
EP2255809B1 (en) | 2017-08-23 |
EP2258355B1 (en) | 2020-01-22 |
US20110028880A1 (en) | 2011-02-03 |
US20110008398A1 (en) | 2011-01-13 |
US8580281B2 (en) | 2013-11-12 |
US20110002976A1 (en) | 2011-01-06 |
WO2009107476A1 (ja) | 2009-09-03 |
EP2258355A4 (en) | 2011-05-04 |
EP2255809A1 (en) | 2010-12-01 |
JP5537412B2 (ja) | 2014-07-02 |
JPWO2009107477A1 (ja) | 2011-06-30 |
US8871249B2 (en) | 2014-10-28 |
WO2009107477A1 (ja) | 2009-09-03 |
ES2778724T3 (es) | 2020-08-11 |
JPWO2009107479A1 (ja) | 2011-06-30 |
EP2258355A1 (en) | 2010-12-08 |
JPWO2009107476A1 (ja) | 2011-06-30 |
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