WO2008105038A1 - 抗真菌症用貼付剤 - Google Patents

抗真菌症用貼付剤 Download PDF

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Publication number
WO2008105038A1
WO2008105038A1 PCT/JP2007/053366 JP2007053366W WO2008105038A1 WO 2008105038 A1 WO2008105038 A1 WO 2008105038A1 JP 2007053366 W JP2007053366 W JP 2007053366W WO 2008105038 A1 WO2008105038 A1 WO 2008105038A1
Authority
WO
WIPO (PCT)
Prior art keywords
skin
nail
mycosis
adhesive layer
adhesive patch
Prior art date
Application number
PCT/JP2007/053366
Other languages
English (en)
French (fr)
Inventor
Koji Kawahara
Noriko Shimada
Original Assignee
Nichiban Company Limited
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Nichiban Company Limited filed Critical Nichiban Company Limited
Priority to PCT/JP2007/053366 priority Critical patent/WO2008105038A1/ja
Priority to PCT/JP2008/053085 priority patent/WO2008102880A1/ja
Priority to JP2008534591A priority patent/JP4430120B2/ja
Priority to CNA2008800001187A priority patent/CN101541315A/zh
Priority to US12/226,375 priority patent/US20090203797A1/en
Priority to RU2008146786/15A priority patent/RU2008146786A/ru
Priority to EP08711853A priority patent/EP2113249A4/en
Publication of WO2008105038A1 publication Critical patent/WO2008105038A1/ja
Priority to JP2009165382A priority patent/JP2009242424A/ja

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
    • A61K31/137—Arylalkylamines, e.g. amphetamine, epinephrine, salbutamol, ephedrine or methadone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
    • A61K9/703—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
    • A61K9/7038—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer
    • A61K9/7046—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds
    • A61K9/7053—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds obtained by reactions only involving carbon to carbon unsaturated bonds, e.g. polyvinyl, polyisobutylene, polystyrene
    • A61K9/7061—Polyacrylates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
    • A61K9/703—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
    • A61K9/7038—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer
    • A61K9/7046—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds
    • A61K9/7069—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds obtained otherwise than by reactions only involving carbon to carbon unsaturated bonds, e.g. polysiloxane, polyesters, polyurethane, polyethylene oxide
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/10—Antimycotics

Landscapes

  • Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Dermatology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Emergency Medicine (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

　薬剤の結晶析出を防止する溶解剤や、爪及び／又は皮膚へ薬剤の浸透を促す促進剤を加えることなく、爪及び／又は皮膚角質層において薬物濃度を長時間高濃度で維持することができ、長時間貼付においても優れた付着性を有し、皮膚刺激性の少ない、真菌症の予防又は治療用の爪及び／又は皮膚用貼付剤を提供する。 　真菌症の予防又は治療用の爪及び／又は皮膚用貼付剤であって、アクリル系粘着剤層又はシリコーン系粘着剤層に、オクタノール／水分配係数であるlogKo/w値が４以上である抗真菌剤を溶解状態で含有する貼付剤。
PCT/JP2007/053366 2007-02-23 2007-02-23 抗真菌症用貼付剤 WO2008105038A1 (ja)

Priority Applications (8)

Application Number Priority Date Filing Date Title
PCT/JP2007/053366 WO2008105038A1 (ja) 2007-02-23 2007-02-23 抗真菌症用貼付剤
PCT/JP2008/053085 WO2008102880A1 (ja) 2007-02-23 2008-02-22 抗真菌症用貼付剤
JP2008534591A JP4430120B2 (ja) 2007-02-23 2008-02-22 抗真菌症用貼付剤
CNA2008800001187A CN101541315A (zh) 2007-02-23 2008-02-22 抗真菌病用贴剂
US12/226,375 US20090203797A1 (en) 2007-02-23 2008-02-22 Antimycotic Patch
RU2008146786/15A RU2008146786A (ru) 2007-02-23 2008-02-22 Противогрибковый пластырь
EP08711853A EP2113249A4 (en) 2007-02-23 2008-02-22 ANTIMYCOTIC STAMP
JP2009165382A JP2009242424A (ja) 2007-02-23 2009-07-14 抗真菌症用貼付剤

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PCT/JP2007/053366 WO2008105038A1 (ja) 2007-02-23 2007-02-23 抗真菌症用貼付剤

Publications (1)

Publication Number Publication Date
WO2008105038A1 true WO2008105038A1 (ja) 2008-09-04

Family

ID=39710151

Family Applications (2)

Application Number Title Priority Date Filing Date
PCT/JP2007/053366 WO2008105038A1 (ja) 2007-02-23 2007-02-23 抗真菌症用貼付剤
PCT/JP2008/053085 WO2008102880A1 (ja) 2007-02-23 2008-02-22 抗真菌症用貼付剤

Family Applications After (1)

Application Number Title Priority Date Filing Date
PCT/JP2008/053085 WO2008102880A1 (ja) 2007-02-23 2008-02-22 抗真菌症用貼付剤

Country Status (6)

Country Link
US (1) US20090203797A1 (ja)
EP (1) EP2113249A4 (ja)
JP (1) JP4430120B2 (ja)
CN (1) CN101541315A (ja)
RU (1) RU2008146786A (ja)
WO (2) WO2008105038A1 (ja)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2011096566A1 (ja) * 2010-02-05 2011-08-11 久光製薬株式会社 爪白癬治療用貼付剤
WO2011136330A1 (ja) * 2010-04-30 2011-11-03 ニチバン株式会社 貼付剤とその使用

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP5194801B2 (ja) * 2006-02-10 2013-05-08 旭硝子株式会社 ウレタン樹脂の製造方法および粘着剤
WO2008026381A1 (en) * 2006-08-28 2008-03-06 Hisamitsu Pharmaceutical Co., Inc. Nail patch
EP2255809B1 (en) * 2008-02-27 2017-08-23 Hisamitsu Pharmaceutical Co., Inc. Medicated patch
WO2009107478A1 (ja) * 2008-02-27 2009-09-03 久光製薬株式会社 貼付剤及び包装体
RU2609017C1 (ru) * 2015-08-07 2017-01-30 Павел Куприянович Сазонов Способ лечения грибковых заболеваний ногтей
JP6715071B2 (ja) 2016-04-27 2020-07-01 信越化学工業株式会社 耐加水分解性シリコーン化合物及びその製造方法

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH10330247A (ja) * 1997-06-02 1998-12-15 Pola Chem Ind Inc 爪用の貼付剤
JP2002363070A (ja) * 2001-06-06 2002-12-18 Yuutoku Yakuhin Kogyo Kk 経皮吸収貼付剤
JP2003525641A (ja) * 1998-02-12 2003-09-02 ワトソン ファーマスーティカルズ，インコーポレイテッド 爪真菌症の治療用感圧接着性マトリックス・パッチ
JP2005501885A (ja) * 2001-09-04 2005-01-20 トロムスドルフ ゲーエムベーハー ウント コンパニー カーゲー アルツナイミッテル 爪の成長の機能障害および疾患を治療するための硬膏

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HU223343B1 (hu) * 1991-05-20 2004-06-28 Novartis Ag. Allil-amin-származékot tartalmazó gyógyászati készítmények és eljárás azok előállítására
EP0983037B1 (en) * 1998-02-09 2003-05-02 MacroChem Corporation Antifungal nail lacquer
US20030124176A1 (en) * 1999-12-16 2003-07-03 Tsung-Min Hsu Transdermal and topical administration of drugs using basic permeation enhancers
US6585963B1 (en) * 2001-02-15 2003-07-01 Watson Pharmaceuticals, Inc. Nail compositions and methods of administering same
US20040258739A1 (en) * 2001-09-04 2004-12-23 Rudy Susilo Plaster for the treatment of dysfunctions and disorders of nails
AU2002364893A1 (en) * 2001-10-22 2003-06-17 University Of Mississippi Delivery of medicaments to the nail
JP4704764B2 (ja) * 2005-02-03 2011-06-22 日東電工株式会社 爪貼付用粘着組成物および爪用貼付剤
JP5015562B2 (ja) * 2005-12-13 2012-08-29 日東電工株式会社 貼付製剤

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH10330247A (ja) * 1997-06-02 1998-12-15 Pola Chem Ind Inc 爪用の貼付剤
JP2003525641A (ja) * 1998-02-12 2003-09-02 ワトソン ファーマスーティカルズ，インコーポレイテッド 爪真菌症の治療用感圧接着性マトリックス・パッチ
JP2002363070A (ja) * 2001-06-06 2002-12-18 Yuutoku Yakuhin Kogyo Kk 経皮吸収貼付剤
JP2005501885A (ja) * 2001-09-04 2005-01-20 トロムスドルフ ゲーエムベーハー ウント コンパニー カーゲー アルツナイミッテル 爪の成長の機能障害および疾患を治療するための硬膏

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
ALBERTI I. ET AL.: "In vivo assessment of enhanced topical delivery of terbinafine to human stratum corneum", J. CONTROL RELEASE, vol. 71, no. 3, 2001, pages 319 - 327, XP004232851 *

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2011096566A1 (ja) * 2010-02-05 2011-08-11 久光製薬株式会社 爪白癬治療用貼付剤
JPWO2011096566A1 (ja) * 2010-02-05 2013-06-13 久光製薬株式会社 爪白癬治療用貼付剤
US8574621B2 (en) 2010-02-05 2013-11-05 Hisamitsu Pharmaceutical Co., Inc. Adhesive patch for treatment of tinea unguium
WO2011136330A1 (ja) * 2010-04-30 2011-11-03 ニチバン株式会社 貼付剤とその使用

Also Published As

Publication number Publication date
EP2113249A4 (en) 2012-09-12
EP2113249A1 (en) 2009-11-04
JP4430120B2 (ja) 2010-03-10
CN101541315A (zh) 2009-09-23
WO2008102880A1 (ja) 2008-08-28
RU2008146786A (ru) 2010-06-10
US20090203797A1 (en) 2009-08-13
JPWO2008102880A1 (ja) 2010-05-27

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