CO7240370A2 - Forma farmaceútica para la liberación prolongada de sustancias activas - Google Patents

Forma farmaceútica para la liberación prolongada de sustancias activas

Info

Publication number
CO7240370A2
CO7240370A2 CO15007539A CO15007539A CO7240370A2 CO 7240370 A2 CO7240370 A2 CO 7240370A2 CO 15007539 A CO15007539 A CO 15007539A CO 15007539 A CO15007539 A CO 15007539A CO 7240370 A2 CO7240370 A2 CO 7240370A2
Authority
CO
Colombia
Prior art keywords
pharmaceutical form
active substances
prolonged release
active substance
release
Prior art date
Application number
CO15007539A
Other languages
English (en)
Inventor
Gernot Francas
Karl-Heinz Przyklenk
Original Assignee
Hennig Arzneimittel Gmbh & Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hennig Arzneimittel Gmbh & Co filed Critical Hennig Arzneimittel Gmbh & Co
Publication of CO7240370A2 publication Critical patent/CO7240370A2/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
    • A61K9/2086—Layered tablets, e.g. bilayer tablets; Tablets of the type inert core-active coat
    • A61K9/209—Layered tablets, e.g. bilayer tablets; Tablets of the type inert core-active coat containing drug in at least two layers or in the core and in at least one outer layer
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0002—Galenical forms characterised by the drug release technique; Application systems commanded by energy
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/141—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers
    • A61K9/145—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers with organic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/141—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers
    • A61K9/146—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers with organic macromolecular compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2013—Organic compounds, e.g. phospholipids, fats
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2013—Organic compounds, e.g. phospholipids, fats
    • A61K9/2018—Sugars, or sugar alcohols, e.g. lactose, mannitol; Derivatives thereof, e.g. polysorbates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/2031—Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, polyethylene oxide, poloxamers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A61K9/2054—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose

Abstract

Se describe una forma farmacéutica, que hace posible liberar uniformemente una sustancia activa durante un período de tiempo prolongado. La forma farmacéutica comprende un emulsionante con un motivo estructura de óxido de polialquileno. La forma farmacéutica es adecuada para liberar una segunda sustancia activa junto con la primera sustancia activa. Se obtiene una liberación uniforme aun cuando dos sustancias activas tienen propiedades completamente diferentes en términos de solubilidad. También se describe un método para la producción de la forma farmacéutica y su uso.
CO15007539A 2012-06-25 2015-01-15 Forma farmaceútica para la liberación prolongada de sustancias activas CO7240370A2 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE102012105512.2A DE102012105512A1 (de) 2012-06-25 2012-06-25 Arzneiform zur verlängerten Freisetzung von Wirkstoffen

Publications (1)

Publication Number Publication Date
CO7240370A2 true CO7240370A2 (es) 2015-04-17

Family

ID=48670585

Family Applications (1)

Application Number Title Priority Date Filing Date
CO15007539A CO7240370A2 (es) 2012-06-25 2015-01-15 Forma farmaceútica para la liberación prolongada de sustancias activas

Country Status (22)

Country Link
EP (1) EP2863891B1 (es)
KR (1) KR102160837B1 (es)
AU (1) AU2013283474B2 (es)
BR (1) BR112014032583B1 (es)
CA (1) CA2876294C (es)
CO (1) CO7240370A2 (es)
DE (1) DE102012105512A1 (es)
EA (2) EA035815B1 (es)
ES (1) ES2817248T3 (es)
HR (1) HRP20201534T1 (es)
HU (1) HUE050945T2 (es)
IL (1) IL236465B (es)
IN (1) IN2014MN02511A (es)
LT (1) LT2863891T (es)
MX (1) MX371143B (es)
PH (1) PH12014502834A1 (es)
PL (1) PL2863891T3 (es)
PT (1) PT2863891T (es)
RS (1) RS60872B1 (es)
SI (1) SI2863891T1 (es)
UA (1) UA116776C2 (es)
WO (1) WO2014001268A1 (es)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2015023675A2 (en) 2013-08-12 2015-02-19 Pharmaceutical Manufacturing Research Services, Inc. Extruded immediate release abuse deterrent pill
US9492444B2 (en) 2013-12-17 2016-11-15 Pharmaceutical Manufacturing Research Services, Inc. Extruded extended release abuse deterrent pill
WO2015095391A1 (en) 2013-12-17 2015-06-25 Pharmaceutical Manufacturing Research Services, Inc. Extruded extended release abuse deterrent pill
LT2959887T (lt) * 2014-06-26 2019-03-12 Hennig Arzneimittel Gmbh&Co. Kg Vaistai galvos svaigimo, atsiradusio dėl įvairių priežasčių, gydymui
WO2016010771A1 (en) 2014-07-17 2016-01-21 Pharmaceutical Manufacturing Research Services, Inc. Immediate release abuse deterrent liquid fill dosage form
JP2017531026A (ja) 2014-10-20 2017-10-19 ファーマシューティカル マニュファクチュアリング リサーチ サービシズ，インコーポレーテッド 徐放性乱用抑止性液体充填剤形
KR101625344B1 (ko) * 2015-12-21 2016-06-08 주식회사 유영제약 세레콕시브 및 둘록세틴을 함유하는 약제학적 조성물

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GB9405304D0 (en) * 1994-03-16 1994-04-27 Scherer Ltd R P Delivery systems for hydrophobic drugs
IE80467B1 (en) * 1995-07-03 1998-07-29 Elan Corp Plc Controlled release formulations for poorly soluble drugs
DE69811233T2 (de) * 1997-10-27 2003-11-20 Merck Patent Gmbh Feste lösungen und dispersionen von eines schlecht wasserlöslichen wirkstoffes
US6368622B2 (en) * 1999-01-29 2002-04-09 Abbott Laboratories Process for preparing solid formulations of lipid regulating agents with enhanced dissolution and absorption
US7374779B2 (en) * 1999-02-26 2008-05-20 Lipocine, Inc. Pharmaceutical formulations and systems for improved absorption and multistage release of active agents
CA2551254A1 (en) * 2003-12-31 2005-07-21 Pfizer Products Inc. Stabilized pharmaceutical solid compositions of low-solubility drugs, poloxamers, and stabilizing polymers
US20050281876A1 (en) * 2004-06-18 2005-12-22 Shun-Por Li Solid dosage form for acid-labile active ingredient
DE102005014141B4 (de) * 2005-03-23 2006-12-21 Hennig Arzneimittel Gmbh & Co. Kg Tablettenförmige Retardzubereitung gegen Schwindel
WO2007056078A2 (en) 2005-11-02 2007-05-18 Cytokinetics, Inc. Certain chemical entities, compositions, and methods
WO2007086078A2 (en) * 2006-01-30 2007-08-02 Panacea Biotec Ltd. Novel pharmaceutical compositions and process of preparation thereof
CN101049309A (zh) * 2006-04-03 2007-10-10 陈茜 桂利嗪滴丸及其制备方法
PL2200588T3 (pl) * 2007-09-25 2019-09-30 Solubest Ltd. Kompozycje zawierające lipofilowe związki aktywne i sposób ich wytwarzania
AU2008334580A1 (en) * 2007-12-12 2009-06-18 Basf Se Salts of active ingredients with polymeric counter-ions
US20120134921A1 (en) * 2009-06-11 2012-05-31 Photocure Asa Solid compositions comprising 5-aminolevulinic acid
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DE102011051308A1 (de) * 2011-06-24 2012-12-27 Hennig Arzneimittel Gmbh & Co. Kg Herstellungsverfahren und Arzneiform
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Also Published As

Publication number Publication date
RS60872B1 (sr) 2020-11-30
BR112014032583B1 (pt) 2022-05-17
LT2863891T (lt) 2020-12-10
EP2863891B1 (de) 2020-08-26
CA2876294A1 (en) 2014-01-03
KR20150041612A (ko) 2015-04-16
BR112014032583A2 (pt) 2017-06-27
PH12014502834B1 (en) 2015-02-02
MX2014015642A (es) 2015-08-05
ES2817248T3 (es) 2021-04-06
PT2863891T (pt) 2020-09-25
EP2863891A1 (de) 2015-04-29
DE102012105512A1 (de) 2014-04-24
MX371143B (es) 2020-01-20
EA028064B1 (ru) 2017-10-31
EA035815B1 (ru) 2020-08-14
UA116776C2 (uk) 2018-05-10
CA2876294C (en) 2020-09-08
PH12014502834A1 (en) 2015-02-02
HUE050945T2 (hu) 2021-01-28
SI2863891T1 (sl) 2020-11-30
EA201500043A1 (ru) 2015-09-30
AU2013283474A1 (en) 2015-01-29
IN2014MN02511A (es) 2015-07-17
IL236465B (en) 2020-06-30
BR112014032583A8 (pt) 2021-06-22
KR102160837B1 (ko) 2020-09-29
HRP20201534T1 (hr) 2021-02-19
PL2863891T3 (pl) 2021-01-25
IL236465A0 (en) 2015-02-26
EA201792143A1 (ru) 2018-05-31
WO2014001268A1 (de) 2014-01-03
AU2013283474B2 (en) 2017-12-14

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