ES2531339T3 - Materiales para dispositivo oftálmico hidrófobo de baja adherencia - Google Patents

Materiales para dispositivo oftálmico hidrófobo de baja adherencia Download PDF

Info

Publication number
ES2531339T3
ES2531339T3 ES12706743T ES12706743T ES2531339T3 ES 2531339 T3 ES2531339 T3 ES 2531339T3 ES 12706743 T ES12706743 T ES 12706743T ES 12706743 T ES12706743 T ES 12706743T ES 2531339 T3 ES2531339 T3 ES 2531339T3
Authority
ES
Spain
Prior art keywords
formula
ophthalmic device
monomer
materials
low adhesion
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
ES12706743T
Other languages
English (en)
Inventor
Walter R Laredo
Xuwei Jiang
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Novartis AG
Original Assignee
Novartis AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novartis AG filed Critical Novartis AG
Application granted granted Critical
Publication of ES2531339T3 publication Critical patent/ES2531339T3/es
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • GPHYSICS
    • G02OPTICS
    • G02BOPTICAL ELEMENTS, SYSTEMS OR APPARATUS
    • G02B1/00Optical elements characterised by the material of which they are made; Optical coatings for optical elements
    • G02B1/04Optical elements characterised by the material of which they are made; Optical coatings for optical elements made of organic materials, e.g. plastics
    • GPHYSICS
    • G02OPTICS
    • G02BOPTICAL ELEMENTS, SYSTEMS OR APPARATUS
    • G02B1/00Optical elements characterised by the material of which they are made; Optical coatings for optical elements
    • G02B1/04Optical elements characterised by the material of which they are made; Optical coatings for optical elements made of organic materials, e.g. plastics
    • G02B1/041Lenses
    • G02B1/043Contact lenses

Landscapes

  • Physics & Mathematics (AREA)
  • General Physics & Mathematics (AREA)
  • Optics & Photonics (AREA)
  • Materials For Medical Uses (AREA)
  • Prostheses (AREA)
  • Addition Polymer Or Copolymer, Post-Treatments, Or Chemical Modifications (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Eyeglasses (AREA)
  • Polymers & Plastics (AREA)
  • Organic Chemistry (AREA)
  • Silicon Polymers (AREA)
  • Graft Or Block Polymers (AREA)
  • Macromonomer-Based Addition Polymer (AREA)

Abstract

Un material copolimérico para dispositivo oftálmico formado polimerizando una mezcla que comprende a) 50% (p/p) o más de un monómero hidrófobo acrílico arilo de fórmula**Fórmula** en la que: A es H; B es (CH2)m, S(CH2)u, O(CH2)v, o [O(CH2)2]n; u es 1 - 4; v es 1 - 4; C es (CH2)w; m es 1 - 6; n es 1 - 10; Y es nada, O, S o NR, a condicioón de que si Y es O, S o NR, entonces B es (CH2)m, R es H, CH3, CnH2n+1 (n >=1-10), iso-OC3H7, C6H5 o CH2C6H5; w es 0 - 6, a condicioón de que m + w <= 8; y D es H, alquilo C1-C4, alcoxi C1-C4, C6H5, CH2C6H5, Br, F, CI o I; b) 0,3 -10% (p/p) de un copolímero en bloque ABA poli(etilenglicol) - polidimetilsiloxano-poli(etilenglicol) terminado con acriloxi de fórmula 1:**Fórmula** en la que R1 es H o CH3; x es 1 - 20; y es 3 -8: y a es 1 - 25; c) 5 - 30% (p/p) de un monómero siloxano de fórmula 2:**Fórmula** en la que R2 es H o CH3; G es nada, O(CH2)z u OCH2CH(OH)CH2; z es 1 - 3; J es (CH2)z; y K1, K2 y K3 independientemente son CH3, C6H5 u OSi(CH3)3; d) 2 - 20% (p/p) de un monómero hidrófilo seleccionado de entre el grupo que consiste en hidroxi(alquil C2- C4)metacrilatos, metacrilato de glicerol y N-viniIpirrolidona; e) un monómero reticulante; y f) un absorbente reactivo de UV.
ES12706743T 2011-02-08 2012-02-07 Materiales para dispositivo oftálmico hidrófobo de baja adherencia Active ES2531339T3 (es)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201161440633P 2011-02-08 2011-02-08
US201161493654P 2011-06-06 2011-06-06
PCT/US2012/024125 WO2012109228A1 (en) 2011-02-08 2012-02-07 Low-tack, hydrophobic ophthalmic device materials

Publications (1)

Publication Number Publication Date
ES2531339T3 true ES2531339T3 (es) 2015-03-13

Family

ID=45774329

Family Applications (1)

Application Number Title Priority Date Filing Date
ES12706743T Active ES2531339T3 (es) 2011-02-08 2012-02-07 Materiales para dispositivo oftálmico hidrófobo de baja adherencia

Country Status (18)

Country Link
US (1) US8969429B2 (es)
EP (1) EP2673666B1 (es)
JP (1) JP5868430B2 (es)
KR (1) KR101729641B1 (es)
CN (1) CN103348266B (es)
AR (1) AR085320A1 (es)
AU (1) AU2012214565B2 (es)
BR (1) BR112013020024A2 (es)
CA (1) CA2825359C (es)
ES (1) ES2531339T3 (es)
HK (1) HK1187415A1 (es)
IL (1) IL227372A (es)
MX (1) MX346220B (es)
RU (1) RU2570575C2 (es)
SG (1) SG192685A1 (es)
TW (1) TWI517861B (es)
WO (1) WO2012109228A1 (es)
ZA (1) ZA201305156B (es)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TWI513768B (zh) * 2011-06-01 2015-12-21 Novartis Ag 疏水性丙烯酸系眼內水晶體材料
US9188702B2 (en) * 2011-09-30 2015-11-17 Johnson & Johnson Vision Care, Inc. Silicone hydrogels having improved curing speed and other properties
JP6023340B2 (ja) * 2012-10-15 2016-11-09 ノバルティス アーゲー 粘着性の低い高屈折率眼用デバイス材料
EP3077016B1 (en) * 2013-12-04 2018-05-16 Novartis AG Soft acrylic materials with high refractive index and minimized glistening
CN115553973A (zh) 2014-05-07 2023-01-03 土耳其科学技术研究理事会 一种人工晶状体和制备方法
CN106999628A (zh) * 2014-12-16 2017-08-01 诺华股份有限公司 用于眼科装置的疏水性丙烯酸酯‑丙烯酰胺共聚物
JP6371480B2 (ja) * 2014-12-16 2018-08-08 ノバルティス アーゲー 眼科用装具のための低含水率アクリレート−アクリルアミドコポリマー
WO2016201351A1 (en) * 2015-06-10 2016-12-15 Powervision, Inc. Intraocular lens materials and components
US20210322152A1 (en) * 2020-04-15 2021-10-21 Rxsight, Inc. Composite light adjustable intraocular lens with adhesion promoter
TW201927263A (zh) 2017-12-18 2019-07-16 瑞士商諾華公司 觸覺力分佈得到改善的眼內透鏡平台
TW201927262A (zh) 2017-12-20 2019-07-16 瑞士商諾華公司 具有前偏置光學設計之眼內透鏡
JP6784720B2 (ja) * 2018-06-01 2020-11-11 上海富吉医療器械有限公司Shanghai Chartwell Medical Instrument Co., Ltd. ポリマー材料および眼内レンズ
CN109898176B (zh) * 2019-02-01 2021-07-02 东华大学 一种柔性可拉伸水凝胶光导纤维传感器及其制备和应用
CN113795283A (zh) * 2019-03-07 2021-12-14 徳雷安控股有限公司 人工晶体组合物
US11708440B2 (en) 2019-05-03 2023-07-25 Johnson & Johnson Surgical Vision, Inc. High refractive index, high Abbe compositions
CN112292100A (zh) 2019-05-03 2021-01-29 强生外科视力公司 高反应指数、高色散系数的组合物
CN116925281A (zh) * 2019-12-24 2023-10-24 爱博诺德(北京)医疗科技股份有限公司 眼科材料及其制备方法
CN113021738B (zh) * 2019-12-24 2023-06-27 烟台爱博诺德医用材料有限公司 眼科材料的制备方法
US11795252B2 (en) 2020-10-29 2023-10-24 Johnson & Johnson Surgical Vision, Inc. Compositions with high refractive index and Abbe number
TWI793944B (zh) * 2021-12-24 2023-02-21 永勝光學股份有限公司 過濾藍光之眼用鏡片及過濾藍光之眼用鏡片的製作方法

Family Cites Families (55)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3665060A (en) * 1969-11-17 1972-05-23 Monsanto Co Resin blend containing ethylene/vinyl chloride interpolymer
US3755219A (en) * 1969-11-17 1973-08-28 Monsanto Co Resin blend containing ethylene/vinyl chloride interpolymer
US4243564A (en) * 1979-05-18 1981-01-06 Moses Konigsberg Reaction products of a hydrolyzed styrene-maleic anhydride copolymer and a dispersed high amylopectin starch product neutralized with a volatile alkali, method of making same, and coating compositions comprising same
US4260725A (en) 1979-12-10 1981-04-07 Bausch & Lomb Incorporated Hydrophilic contact lens made from polysiloxanes which are thermally bonded to polymerizable groups and which contain hydrophilic sidechains
US4259467A (en) 1979-12-10 1981-03-31 Bausch & Lomb Incorporated Hydrophilic contact lens made from polysiloxanes containing hydrophilic sidechains
US4361669A (en) * 1981-08-17 1982-11-30 Champion International Corporation Coating compositions comprising a reaction product of a dispersed _hydroxy-alkyl modified starch product and a hydrolyzed styrene maleic anhydride copolymer
US4605712A (en) 1984-09-24 1986-08-12 Ciba-Geigy Corporation Unsaturated polysiloxanes and polymers thereof
US4834750A (en) 1987-09-17 1989-05-30 Ioptex Research, Inc. Deformable-elastic intraocular lens
US4906718A (en) 1988-12-09 1990-03-06 Dow Corning Corporation Acrylate functional organosiloxane/oxyalkylene copolymers and electrically conductive compositions containing same and a solubilized lithium salt
US5290892A (en) 1990-11-07 1994-03-01 Nestle S.A. Flexible intraocular lenses made from high refractive index polymers
JPH0632855A (ja) * 1992-07-14 1994-02-08 Nippon Contact Lens Kk ガス透過性高分子材料
US5260000A (en) * 1992-08-03 1993-11-09 Bausch & Lomb Incorporated Process for making silicone containing hydrogel lenses
US5331073A (en) * 1992-11-09 1994-07-19 Allergan, Inc. Polymeric compositions and intraocular lenses made from same
RU2058329C1 (ru) * 1993-01-28 1996-04-20 Московский научно-исследовательский институт глазных болезней им.Гельмгольца Способ получения сшитого сополимера для контактных линз
US5603774A (en) 1993-09-27 1997-02-18 Alcon Laboratories, Inc. Method for reducing tackiness of soft acrylic polymers
US5470932A (en) 1993-10-18 1995-11-28 Alcon Laboratories, Inc. Polymerizable yellow dyes and their use in opthalmic lenses
JP3222026B2 (ja) * 1994-12-26 2001-10-22 株式会社メニコン コンタクトレンズ材料および眼内レンズ材料
EP0774983B1 (en) * 1995-06-07 2002-12-04 Alcon Laboratories, Inc. Improved high refractive index ophthalmic lens materials
SE9600006D0 (sv) * 1996-01-02 1996-01-02 Pharmacia Ab Foldable intraocular lens materials
US5728156A (en) * 1996-08-06 1998-03-17 Prism Opthalmics, L.L.C. Prismatic intraocular lenses and related methods of in situ alteration of their optical characteristics
WO1999053347A1 (en) * 1998-04-15 1999-10-21 Alcon Laboratories, Inc. High refractive index ophthalmic device materials
US6241766B1 (en) 1998-10-29 2001-06-05 Allergan Sales, Inc. Intraocular lenses made from polymeric compositions
EP1210381A1 (en) * 1999-09-07 2002-06-05 Alcon Universal, Ltd. Ophthalmic and otorhinolaryngological device materials
JP5459816B2 (ja) 1999-09-07 2014-04-02 アルコン,インコーポレイテッド 折り畳み可能な眼科用および耳鼻咽喉科用のデバイス材料
AU779729B2 (en) 1999-12-16 2005-02-10 Coopervision International Limited Soft contact lens capable of being worn for a long period
KR100419864B1 (ko) 2001-11-15 2004-03-04 한국화학연구원 신규 가교제와 이를 함유하는 가교형 고체 고분자 전해질
US6933078B2 (en) 2002-12-18 2005-08-23 Valence Technology, Inc. Crosslinked polymer electrolytes and method of making such crosslinked polymers
WO2005066662A1 (en) 2003-12-30 2005-07-21 Advanced Medical Optics, Inc. Intraocular lens materials suitable for insertion through a small bore cartridge
SG155241A1 (en) 2004-08-27 2009-09-30 Asahikasei Aime Co Ltd Silicone hydrogel contact lenses
CA2609857C (en) * 2005-06-13 2013-11-12 Alcon, Inc. Ophthalmic and otorhinolaryngological device materials
US7763682B2 (en) 2006-03-27 2010-07-27 Abbott Medical Optics Inc. Hybrid intraocular lens materials for small incision surgery
US8231218B2 (en) * 2006-06-15 2012-07-31 Coopervision International Holding Company, Lp Wettable silicone hydrogel contact lenses and related compositions and methods
EP2046880B1 (en) * 2006-07-18 2020-11-25 Solenis Technologies Cayman, L.P. Stable adhesives from urea-denatured soy flour
TW200816966A (en) 2006-07-21 2008-04-16 Alcon Mfg Ltd Low-tack ophthalmic and otorhinolaryngological device materials
US8058323B2 (en) 2006-07-21 2011-11-15 Novartis Ag Low-tack ophthalmic and otorhinolaryngological device materials
US7714039B2 (en) 2006-07-21 2010-05-11 Alcon, Inc. Low-tack ophthalmic and otorhinolaryngological device materials
TWI399228B (zh) 2006-07-21 2013-06-21 Alcon Inc 低黏性的眼科與耳鼻喉科裝置材料(二)
US7829611B2 (en) * 2006-08-24 2010-11-09 Rohm And Haas Company Curable composition
TW200920330A (en) 2007-10-02 2009-05-16 Alcon Inc Ophthalmic and otorhinolaryngological device materials containing an alkyl ethoxylate
TW200916130A (en) 2007-10-02 2009-04-16 Alcon Inc Ophthalmic and otorhinolaryngological device materials containing an alkylphenol ethoxylate
TWI426931B (zh) 2007-10-03 2014-02-21 Alcon Inc 眼科與耳鼻喉科裝置材料(一)
TWI461186B (zh) 2007-10-05 2014-11-21 Alcon Inc 眼科與耳鼻喉科裝置材料(二)
TWI426932B (zh) 2007-10-05 2014-02-21 Alcon Inc 眼科與耳鼻喉科裝置材料(三)
JP4789995B2 (ja) * 2007-12-26 2011-10-12 ローム アンド ハース カンパニー コンポジット材料及びその製造方法
ES2431353T3 (es) * 2008-02-08 2013-11-26 Coopervision International Holding Company, Lp Monómero de polisiloxano hidrofílico, y método de producción y aplicación del mismo
US20100069522A1 (en) 2008-03-17 2010-03-18 Linhardt Jeffrey G Lenses comprising amphiphilic multiblock copolymers
US20090258042A1 (en) * 2008-04-14 2009-10-15 Theodore James Anastasiou Encapsulated Active Materials Containing Adjunct Crosslinkers
TW201000155A (en) * 2008-05-06 2010-01-01 Alcon Inc High refractive index ophthalmic device materials
JP4646152B2 (ja) 2008-05-27 2011-03-09 信越化学工業株式会社 眼科デバイス製造用モノマー
JP2010095589A (ja) 2008-10-15 2010-04-30 Shin-Etsu Chemical Co Ltd 眼科デバイス製造用シリコーン
TWI487690B (zh) 2009-07-06 2015-06-11 Alcon Inc 用於眼用鏡片材料之可見光吸收劑
TWI473629B (zh) 2010-01-18 2015-02-21 Alcon Inc 用於眼用晶體材料之可見光吸收劑
US8680224B2 (en) * 2010-02-01 2014-03-25 Johns Manville Formaldehyde-free protein-containing binder compositions
US8937025B2 (en) * 2010-02-01 2015-01-20 Johns Manville Formaldehyde-free protein-containing binders for spunbond products
TWI473823B (zh) 2010-06-21 2015-02-21 Novartis Ag 具有經降低的閃光之高折射率、丙烯酸系眼科裝置材料

Also Published As

Publication number Publication date
BR112013020024A2 (pt) 2017-12-12
TW201235051A (en) 2012-09-01
NZ612852A (en) 2015-01-30
WO2012109228A1 (en) 2012-08-16
JP5868430B2 (ja) 2016-02-24
HK1187415A1 (en) 2014-04-04
IL227372A (en) 2016-02-29
AU2012214565B2 (en) 2014-11-20
CN103348266A (zh) 2013-10-09
TWI517861B (zh) 2016-01-21
RU2013141209A (ru) 2015-03-20
AU2012214565A1 (en) 2013-07-25
KR20140051125A (ko) 2014-04-30
EP2673666B1 (en) 2014-12-31
US8969429B2 (en) 2015-03-03
MX346220B (es) 2017-03-09
ZA201305156B (en) 2014-09-25
CN103348266B (zh) 2016-05-04
JP2014506814A (ja) 2014-03-20
SG192685A1 (en) 2013-09-30
AR085320A1 (es) 2013-09-25
MX2013009141A (es) 2013-10-01
CA2825359C (en) 2018-07-31
EP2673666A1 (en) 2013-12-18
KR101729641B1 (ko) 2017-04-24
RU2570575C2 (ru) 2015-12-10
IL227372A0 (en) 2013-09-30
CA2825359A1 (en) 2012-08-16
US20120202916A1 (en) 2012-08-09

Similar Documents

Publication Publication Date Title
ES2531339T3 (es) Materiales para dispositivo oftálmico hidrófobo de baja adherencia
DE502005011196D1 (de) Polymerzusammensetzung mit hohem Brechungsindex
RU2013157572A (ru) Гидрофобные акриловые материалы для интраокулярных линз
RU2013158651A (ru) Гидрофобные акриловые материалы для интраокулярных линз
BR112013026998A2 (pt) processo de produção de uma composição de polímeros absorventes de água, compósito, processo para produção de um compósito, espumas, moldes, fibras, folhas, películas, cabos, materiais de vedação, artigos de higiene absorventes de líquidos, transportadores para o crescimento de plantas e reguladores de crescimento de fungos, materiais de embalagem, aditivos para o solo ou materiais de construção e uso do polímero absorvente de água ou de um compósito
PE20161251A1 (es) Compuestos heteroarilo o arilo biciclicos fusionados y su uso como inhibidores de irak4
NZ603881A (en) High refractive index, acrylic ophthalmic device materials with reduced glistenings
WO2012004744A3 (en) Polymeric composition for ocular devices
MX2015003363A (es) Polimeros modificados por aminosilano.
ES2570137T3 (es) Composición de agente antiadherente
AR100908A1 (es) Perlas acrílicas para promover la termicidad de películas de invernadero
MX365605B (es) Materiales absorbentes de luz ultravioleta para lente intraocular y uso de los mismos.
RU2013144740A (ru) Способ загущения косметической композиции разбухающей в щелочной среде эмульсией полимера, содержащего amps и имеющего высокое содержание акриловой кислоты
JP2017513596A5 (es)
RU2013106396A (ru) Состав защитного покрытия
US20170204213A1 (en) Silicone hydrogel, medical device, lens for eye and contact lens (as amended)
ATE472571T1 (de) Verfahren zur herstellung von stabilisiertem latex mittels emulsionspolymerisation
TW201346375A (zh) 隱形眼鏡的製造方法與由此方法所製造出之隱形眼鏡
AR123912A2 (es) ANTICUERPOS QUE SE UNEN A TGF-a Y EPIREGULINA
RU2013127662A (ru) Способ получения водных суспензий неорганических веществ при помощи аминов в сочетании с винилкарбоновыми полимерами
RU2013153582A (ru) Макроинициатор, содержащий гидрофобный сегмент
RU2017143467A (ru) Наполнитель для шин на основе акриловых гидрогелей
WO2015153404A1 (en) Silicone acrylamide copolymer
RU2015102158A (ru) 2-аминобензофеноновые уф-абсорберы для материалов офтальмологических линз
RU2014105594A (ru) Композиция ди-(трет-бутилциклогексил)-пероксидикарбоната