ES2515465T3 - Procedimiento para preparar derivados de 2,2-difluoroetilamina mediante alquilación con 2,2-difluoro-1-haloetanos - Google Patents

Procedimiento para preparar derivados de 2,2-difluoroetilamina mediante alquilación con 2,2-difluoro-1-haloetanos Download PDF

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Publication number
ES2515465T3
ES2515465T3 ES11724248.7T ES11724248T ES2515465T3 ES 2515465 T3 ES2515465 T3 ES 2515465T3 ES 11724248 T ES11724248 T ES 11724248T ES 2515465 T3 ES2515465 T3 ES 2515465T3
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ES
Spain
Prior art keywords
methyl
optionally substituted
pyrid
chlorine
general formula
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
ES11724248.7T
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English (en)
Spanish (es)
Inventor
Norbert Lui
Jens-Dietmar Heinrich
Wahed Ahmed Moradi
Christian Funke
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Bayer Intellectual Property GmbH
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Bayer Intellectual Property GmbH
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Application filed by Bayer Intellectual Property GmbH filed Critical Bayer Intellectual Property GmbH
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Publication of ES2515465T3 publication Critical patent/ES2515465T3/es
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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/61—Halogen atoms or nitro radicals
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J27/00—Catalysts comprising the elements or compounds of halogens, sulfur, selenium, tellurium, phosphorus or nitrogen; Catalysts comprising carbon compounds
    • B01J27/06—Halogens; Compounds thereof
    • B01J27/08—Halides

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Materials Engineering (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Pyridine Compounds (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
ES11724248.7T 2010-06-15 2011-06-10 Procedimiento para preparar derivados de 2,2-difluoroetilamina mediante alquilación con 2,2-difluoro-1-haloetanos Active ES2515465T3 (es)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US35493310P 2010-06-15 2010-06-15
EP10166019 2010-06-15
EP10166019 2010-06-15
US354933P 2010-06-15
PCT/EP2011/059691 WO2011157650A1 (de) 2010-06-15 2011-06-10 Verfahren zur herstellung von 2, 2-difluorethylamin- derivaten durch alkylierung mit 2,2- difluor-1-halogenethanen

Publications (1)

Publication Number Publication Date
ES2515465T3 true ES2515465T3 (es) 2014-10-29

Family

ID=43020183

Family Applications (1)

Application Number Title Priority Date Filing Date
ES11724248.7T Active ES2515465T3 (es) 2010-06-15 2011-06-10 Procedimiento para preparar derivados de 2,2-difluoroetilamina mediante alquilación con 2,2-difluoro-1-haloetanos

Country Status (12)

Country Link
US (1) US8466293B2 (zh)
EP (1) EP2582673B1 (zh)
JP (1) JP5848757B2 (zh)
KR (1) KR101790159B1 (zh)
CN (1) CN103003241B (zh)
BR (1) BR112012032251B1 (zh)
DK (1) DK2582673T3 (zh)
ES (1) ES2515465T3 (zh)
IL (1) IL223581A (zh)
MX (1) MX2012014578A (zh)
TW (1) TWI510470B (zh)
WO (1) WO2011157650A1 (zh)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2663539B1 (de) * 2011-01-13 2016-07-27 Bayer Intellectual Property GmbH Verfahren zur herstellung von 2,2-difluorethylamin aus 2,2-difluor-1-chlorethan und ammoniak
US9376389B2 (en) 2012-06-29 2016-06-28 Bayer Cropscience Ag Process for preparing 2,2-difluoroethylamine derivatives by alkylating 2,2-difluoroethylamine
JP6533233B2 (ja) 2014-03-21 2019-06-19 バイエル・クロップサイエンス・アクチェンゲゼルシャフト ２，２−ジフルオロエチルアミンをアルキル化することによりｎ−［（６−クロロピリジノ−３−イル）メチル］−２，２−ジフルオロエタン−１−アミンを調製する方法
CN105801424A (zh) * 2016-04-26 2016-07-27 南通宝凯化工有限公司 一种二氟乙胺的合成工艺
FR3056588B1 (fr) * 2016-09-27 2018-10-12 Arkema France Composition comprenant du 1-chloro-2,2-difluoroethane
JP2019532055A (ja) * 2016-09-27 2019-11-07 アルケマ フランス １−クロロ−２，２−ジフルオロエタンを含む組成物
FR3056586B1 (fr) * 2016-09-27 2020-05-08 Arkema France Composition comprenant du 1-chloro-2,2-difluoroethane
FR3056590B1 (fr) * 2016-09-27 2020-05-08 Arkema France Composition comprenant du 1-chloro-2,2-difluoroethane
FR3056587B1 (fr) * 2016-09-27 2020-05-08 Arkema France Composition comprenant du 1-chloro-2,2-difluoroethane
FR3056585B1 (fr) * 2016-09-27 2020-05-08 Arkema France Composition comprenant du 1-chloro-2,2-difluoroethane
CN107501524B (zh) * 2017-08-30 2020-05-12 本源精化环保科技有限公司 N,n’烷基化二氨基二苯基甲烷类固化剂及制备方法
CN111909044A (zh) * 2019-05-09 2020-11-10 南京爱德程医药科技有限公司 2-(烷基氨基)乙基苯甲酸酯类化合物的合成方法

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4030994A (en) * 1971-06-18 1977-06-21 Merck & Co., Inc. Substitutive fluorination of organic compounds
WO2001044163A1 (en) * 1999-12-16 2001-06-21 Asahi Glass Company, Limited Process for producing fluorinated alkylamine compound
WO2006019965A2 (en) * 2004-07-16 2006-02-23 Takeda San Diego, Inc. Dipeptidyl peptidase inhibitors
DE102006015467A1 (de) 2006-03-31 2007-10-04 Bayer Cropscience Ag Substituierte Enaminocarbonylverbindungen
JP4821849B2 (ja) 2006-04-10 2011-11-24 株式会社村田製作所 複合基板及び複合基板の製造方法
EP2200440B1 (en) * 2007-07-23 2017-07-19 Crestone, Inc. Antibacterial amide and sulfonamide substituted heterocyclic urea compounds
EP2039684A1 (de) * 2007-09-18 2009-03-25 Bayer CropScience AG Verfahren zur Herstellung von 2,2-Difluorethylamin-Derivaten durch Imin-Hydrierung
ES2438568T3 (es) * 2007-09-18 2014-01-17 Bayer Cropscience Ag Procedimiento para la preparación de derivados de 2,2-difluoroetilamina mediante hidrogenación de amida
ES2602582T3 (es) * 2009-07-28 2017-02-21 Bayer Intellectual Property Gmbh Procedimiento para la preparación de 2,2-difluoroetilamina

Also Published As

Publication number Publication date
JP2013530171A (ja) 2013-07-25
BR112012032251A2 (pt) 2015-09-15
BR112012032251B1 (pt) 2017-05-23
KR20130086603A (ko) 2013-08-02
IL223581A (en) 2014-09-30
CN103003241A (zh) 2013-03-27
DK2582673T3 (da) 2014-11-10
EP2582673B1 (de) 2014-08-06
EP2582673A1 (de) 2013-04-24
MX2012014578A (es) 2013-02-07
US20110306770A1 (en) 2011-12-15
US8466293B2 (en) 2013-06-18
TWI510470B (zh) 2015-12-01
TW201213307A (en) 2012-04-01
JP5848757B2 (ja) 2016-01-27
KR101790159B1 (ko) 2017-10-25
WO2011157650A1 (de) 2011-12-22
CN103003241B (zh) 2014-07-30

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