ES2461624T3 - Derivados estables de NAD/NADH - Google Patents

Derivados estables de NAD/NADH Download PDF

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Publication number
ES2461624T3
ES2461624T3 ES11167476.8T ES11167476T ES2461624T3 ES 2461624 T3 ES2461624 T3 ES 2461624T3 ES 11167476 T ES11167476 T ES 11167476T ES 2461624 T3 ES2461624 T3 ES 2461624T3
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ES
Spain
Prior art keywords
respectively independent
dehydrogenase
radical
nad
group
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
ES11167476.8T
Other languages
English (en)
Spanish (es)
Inventor
Joachim Hoenes
Dieter Heindl
Carina Horn
Claudia Gaessler-Dietsche
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F Hoffmann La Roche AG
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F Hoffmann La Roche AG
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Application filed by F Hoffmann La Roche AG filed Critical F Hoffmann La Roche AG
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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/26—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving oxidoreductase
    • C12Q1/32—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving oxidoreductase involving dehydrogenase
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/531—Production of immunochemical test materials
    • G01N33/532—Production of labelled immunochemicals
    • G01N33/533—Production of labelled immunochemicals with fluorescent label

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  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Immunology (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • General Health & Medical Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • Biomedical Technology (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Cell Biology (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Saccharide Compounds (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
ES11167476.8T 2005-07-28 2006-07-28 Derivados estables de NAD/NADH Active ES2461624T3 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE102005035461A DE102005035461A1 (de) 2005-07-28 2005-07-28 Stabile NAD/NADH-Derivate
DE102005035461 2005-07-28

Publications (1)

Publication Number Publication Date
ES2461624T3 true ES2461624T3 (es) 2014-05-20

Family

ID=37137552

Family Applications (3)

Application Number Title Priority Date Filing Date
ES11167476.8T Active ES2461624T3 (es) 2005-07-28 2006-07-28 Derivados estables de NAD/NADH
ES06776486.0T Active ES2461266T3 (es) 2005-07-28 2006-07-28 Derivados estables de NAD/NADH
ES11167471.9T Active ES2453150T3 (es) 2005-07-28 2006-07-28 Derivados estables de NAD/NADH

Family Applications After (2)

Application Number Title Priority Date Filing Date
ES06776486.0T Active ES2461266T3 (es) 2005-07-28 2006-07-28 Derivados estables de NAD/NADH
ES11167471.9T Active ES2453150T3 (es) 2005-07-28 2006-07-28 Derivados estables de NAD/NADH

Country Status (16)

Country Link
US (3) US8809013B2 (https=)
EP (3) EP1907408B1 (https=)
JP (2) JP5129133B2 (https=)
KR (4) KR101035524B1 (https=)
CN (2) CN101233144B (https=)
AU (2) AU2006274140B8 (https=)
BR (1) BRPI0614217A2 (https=)
CA (2) CA2614792C (https=)
DE (1) DE102005035461A1 (https=)
DK (3) DK1907408T3 (https=)
ES (3) ES2461624T3 (https=)
MX (1) MX2008000946A (https=)
PL (3) PL2364988T3 (https=)
PT (3) PT2364989E (https=)
SG (1) SG187511A1 (https=)
WO (1) WO2007012494A1 (https=)

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EP2668161B1 (en) 2011-01-26 2014-11-26 Roche Diagniostics GmbH Method and substances for preparation of n-substituted pyridinium compounds
CN104905799B (zh) 2011-04-12 2018-06-08 霍夫曼-拉罗奇有限公司 分析辅件
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CN102863495A (zh) * 2011-07-06 2013-01-09 上海执诚生物科技股份有限公司 一种含有nad+或nadh的稳定的组合物
KR101609083B1 (ko) 2011-09-28 2016-04-04 에프. 호프만-라 로슈 아게 아조 매개체
JP6128808B2 (ja) * 2011-11-15 2017-05-17 栄研化学株式会社 酵素活性の検出、測定方法およびこれを利用したキット
EP2620507A1 (en) 2012-01-25 2013-07-31 Roche Diagnostics GmbH Method for the evaluation of the quality of a test element
EP2636750A1 (en) 2012-03-06 2013-09-11 Roche Diagniostics GmbH Compatible solute ectoine as well as derivatives thereof for enzyme stabilization
CA2865678C (en) 2012-04-19 2018-03-13 Susanne BALDUS Method and device for determining an analyte concentration in blood
US8921061B2 (en) * 2012-11-02 2014-12-30 Roche Diagnostics Operations, Inc. Reagent materials and associated test elements
US8920628B2 (en) 2012-11-02 2014-12-30 Roche Diagnostics Operations, Inc. Systems and methods for multiple analyte analysis
CN104854457B (zh) 2012-12-20 2016-09-14 霍夫曼-拉罗奇有限公司 用于分析体液样本的方法
HUE034313T2 (en) 2012-12-20 2018-02-28 Hoffmann La Roche Procedures for evaluating medical measurement curves
EP2770064A1 (de) 2013-02-22 2014-08-27 F. Hoffmann-La Roche AG Hocheffiziente Herstellung von Blutglucose-Teststreifen
EP2781919A1 (en) 2013-03-19 2014-09-24 Roche Diagniostics GmbH Method / device for generating a corrected value of an analyte concentration in a sample of a body fluid
EP2994536B1 (en) 2013-05-08 2017-06-14 Roche Diabetes Care GmbH Stabilization of enzymes by nicotinic acid
HK1213296A1 (zh) * 2013-06-04 2016-06-30 豪夫迈‧罗氏有限公司 用於fret的新化合物及与其相关的方法
EP2811299A1 (en) 2013-06-07 2014-12-10 Roche Diagniostics GmbH Test element for detecting at least one analyte in a body fluid
WO2015063025A1 (en) 2013-10-29 2015-05-07 F. Hoffmann-La Roche Ag Nano-enzyme containers for test elements
EP3074524B1 (en) 2013-11-27 2019-11-06 Roche Diabetes Care GmbH Composition comprising up-converting phosphors for detecting an analyte
EP2927319A1 (en) 2014-03-31 2015-10-07 Roche Diagnostics GmbH High load enzyme immobilization by crosslinking
EP3131882B1 (en) 2014-04-14 2020-07-15 Roche Diagnostics GmbH Phenazinium mediators
WO2016022604A2 (en) * 2014-08-05 2016-02-11 Becton Dickinson And Company Methods and compositions for analyzing glucose-6-phosphate dehydrogenase activity in blood samples
EP3757096B1 (en) 2014-08-22 2025-03-12 Roche Diagnostics GmbH Redoxindicators for a use in cell viability testing
BR112017001444B1 (pt) 2014-08-25 2022-08-16 F. Hoffmann-La Roche Ag Método para detectar pelo menos um analito em uma amostra de teste, elemento sensor, dispositivo de teste, sistema de teste, uso do elemento sensor e portador de dados
EP3394252B1 (en) 2015-12-21 2020-04-29 F. Hoffmann-La Roche AG Mutant 3-hydroxybutyrate dehydrogenase from alcaligenes faecalis as well as methods and uses involving the same
ES2782199T3 (es) 2016-02-09 2020-09-11 Hoffmann La Roche 3-Hidroxibutirato deshidrogenasa mutante de Rhodobacter sphaeroides, así como procedimientos y usos que implican la misma
KR102372113B1 (ko) 2016-10-05 2022-03-07 에프. 호프만-라 로슈 아게 다중 분석물 진단 테스트 엘리먼트들을 위한 검출 시약들 및 전극 배열들, 그리고 그것을 사용하는 방법들
EP3339431A1 (en) 2016-12-22 2018-06-27 Roche Diabetes Care GmbH Glucose dehydrogenase variants with improved properties
CN107966555A (zh) * 2017-11-23 2018-04-27 中山市创艺生化工程有限公司 一种用于稳定保存nad或其衍生物的存储液
HUE064713T2 (hu) 2018-02-28 2024-04-28 Hoffmann La Roche Biokompatibilitási bevonat folyamatos analitméréshez
CN111217744A (zh) * 2018-11-26 2020-06-02 中国科学院大连化学物理研究所 一种d-氨基酸基nad+类似物及其合成和应用
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Also Published As

Publication number Publication date
DE102005035461A1 (de) 2007-02-15
PT2364988E (pt) 2014-04-03
US8809013B2 (en) 2014-08-19
CA2614792C (en) 2011-07-12
PL2364988T3 (pl) 2014-08-29
CN101233144A (zh) 2008-07-30
DK1907408T3 (da) 2014-06-10
US20140206024A1 (en) 2014-07-24
JP5650695B2 (ja) 2015-01-07
ES2453150T3 (es) 2014-04-04
KR101035524B1 (ko) 2011-05-23
AU2006274140B8 (en) 2011-02-03
DK2364989T3 (da) 2014-06-10
WO2007012494B1 (de) 2007-03-29
KR101483829B1 (ko) 2015-01-16
US20160326567A1 (en) 2016-11-10
CA2614792A1 (en) 2007-02-01
PL2364989T3 (pl) 2014-08-29
EP2364988A1 (de) 2011-09-14
US20080213809A1 (en) 2008-09-04
US10167497B2 (en) 2019-01-01
JP5129133B2 (ja) 2013-01-23
EP1907408A1 (de) 2008-04-09
CA2737123A1 (en) 2007-02-01
MX2008000946A (es) 2008-03-27
EP1907408B1 (de) 2014-03-05
DK2364988T3 (da) 2014-05-26
EP2364989A1 (de) 2011-09-14
BRPI0614217A2 (pt) 2011-03-22
PT2364989E (pt) 2014-04-04
US9399790B2 (en) 2016-07-26
HK1123308A1 (en) 2009-06-12
KR101483899B1 (ko) 2015-01-16
AU2011200465A1 (en) 2011-02-24
SG187511A1 (en) 2013-02-28
AU2006274140A1 (en) 2007-02-01
CN103122371B (zh) 2016-12-28
KR20140003637A (ko) 2014-01-09
PT1907408E (pt) 2014-03-28
PL1907408T3 (pl) 2014-07-31
CN101233144B (zh) 2013-02-06
AU2011200465B2 (en) 2012-02-09
CN103122371A (zh) 2013-05-29
EP2364989B1 (de) 2014-03-05
KR20120044372A (ko) 2012-05-07
JP2012224638A (ja) 2012-11-15
WO2007012494A1 (de) 2007-02-01
AU2006274140B2 (en) 2010-11-11
JP2009502844A (ja) 2009-01-29
KR20110028522A (ko) 2011-03-18
KR20080028507A (ko) 2008-03-31
EP2364988B1 (de) 2014-02-26
ES2461266T3 (es) 2014-05-19

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