BRPI0614217A2 - derivados de nadh/nad estáveis - Google Patents

derivados de nadh/nad estáveis Download PDF

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Publication number
BRPI0614217A2
BRPI0614217A2 BRPI0614217-6A BRPI0614217A BRPI0614217A2 BR PI0614217 A2 BRPI0614217 A2 BR PI0614217A2 BR PI0614217 A BRPI0614217 A BR PI0614217A BR PI0614217 A2 BRPI0614217 A2 BR PI0614217A2
Authority
BR
Brazil
Prior art keywords
dehydrogenase
case independently
independently means
compound
nad
Prior art date
Application number
BRPI0614217-6A
Other languages
English (en)
Portuguese (pt)
Inventor
Joachim Hoenes
Dieter Heindl
Carina Horn
Claudia Gaessler-Dietsche
Original Assignee
Hoffmann La Roche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche
Publication of BRPI0614217A2 publication Critical patent/BRPI0614217A2/pt

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/26—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving oxidoreductase
    • C12Q1/32—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving oxidoreductase involving dehydrogenase
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/531—Production of immunochemical test materials
    • G01N33/532—Production of labelled immunochemicals
    • G01N33/533—Production of labelled immunochemicals with fluorescent label

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  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Immunology (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • General Health & Medical Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • Biomedical Technology (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Cell Biology (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Saccharide Compounds (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
BRPI0614217-6A 2005-07-28 2006-07-28 derivados de nadh/nad estáveis BRPI0614217A2 (pt)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
DE102005035461A DE102005035461A1 (de) 2005-07-28 2005-07-28 Stabile NAD/NADH-Derivate
DE102005035461.0 2005-07-28
PCT/EP2006/007493 WO2007012494A1 (de) 2005-07-28 2006-07-28 Stabile nad/nadh-derivate

Publications (1)

Publication Number Publication Date
BRPI0614217A2 true BRPI0614217A2 (pt) 2011-03-22

Family

ID=37137552

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0614217-6A BRPI0614217A2 (pt) 2005-07-28 2006-07-28 derivados de nadh/nad estáveis

Country Status (16)

Country Link
US (3) US8809013B2 (https=)
EP (3) EP2364989B1 (https=)
JP (2) JP5129133B2 (https=)
KR (4) KR101483829B1 (https=)
CN (2) CN101233144B (https=)
AU (2) AU2006274140B8 (https=)
BR (1) BRPI0614217A2 (https=)
CA (2) CA2737123A1 (https=)
DE (1) DE102005035461A1 (https=)
DK (3) DK2364988T3 (https=)
ES (3) ES2453150T3 (https=)
MX (1) MX2008000946A (https=)
PL (3) PL2364988T3 (https=)
PT (3) PT2364988E (https=)
SG (1) SG187511A1 (https=)
WO (1) WO2007012494A1 (https=)

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EP2398388B1 (de) * 2009-02-19 2020-04-08 Roche Diabetes Care GmbH Platzsparende magazinierung analytischer hilfsmittel
EP2226007A1 (de) 2009-02-19 2010-09-08 Roche Diagnostics GmbH Testelementmagazin mit abgedeckten Testfeldern
KR20130127555A (ko) * 2009-02-19 2013-11-22 에프. 호프만-라 로슈 아게 건식 화학 층에서 낮은 활성을 갖는 효소의 고속 반응 속도
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JP5540096B2 (ja) * 2009-07-27 2014-07-02 エフ・ホフマン−ラ・ロシュ・アクチェンゲゼルシャフト カルバ−ｎａｄの酵素合成
EP2292751A1 (de) 2009-08-20 2011-03-09 Roche Diagnostics GmbH Stabilisierung von Enzymen mit stabilen Coenzymen
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EP2333544A1 (de) 2009-12-11 2011-06-15 F. Hoffmann-La Roche AG Sterilisierbare Chemie für Testelemente
EP2513648B1 (de) 2009-12-16 2015-05-27 F.Hoffmann-La Roche Ag Detektion der zersetzung von enzymen in einem testelement durch kontrollierte freisetzung von geschütztem analyt
KR101252351B1 (ko) * 2010-05-24 2013-04-08 동국대학교 산학협력단 전기효소적 합성 반응을 위한 ｎａｄ(ｐ) 유도체의 전기화학적 환원 방법
CN102453067B (zh) * 2010-10-29 2015-08-05 中国科学院大连化学物理研究所 一种nad+类似物的制备方法及其应用
ES2529023T3 (es) 2011-01-26 2015-02-16 F. Hoffmann-La Roche Ag Método y sustancias para la preparación de compuestos de piridinio N-sustituidos
CN103458786B (zh) 2011-04-12 2015-08-19 霍夫曼-拉罗奇有限公司 分析辅件
US9752990B2 (en) 2013-09-30 2017-09-05 Honeywell International Inc. Low-powered system for driving a fuel control mechanism
CN102863495A (zh) * 2011-07-06 2013-01-09 上海执诚生物科技股份有限公司 一种含有nad+或nadh的稳定的组合物
KR101609083B1 (ko) 2011-09-28 2016-04-04 에프. 호프만-라 로슈 아게 아조 매개체
JP6128808B2 (ja) * 2011-11-15 2017-05-17 栄研化学株式会社 酵素活性の検出、測定方法およびこれを利用したキット
EP2620507A1 (en) 2012-01-25 2013-07-31 Roche Diagnostics GmbH Method for the evaluation of the quality of a test element
EP2636750A1 (en) 2012-03-06 2013-09-11 Roche Diagniostics GmbH Compatible solute ectoine as well as derivatives thereof for enzyme stabilization
KR101728597B1 (ko) 2012-04-19 2017-04-19 에프. 호프만-라 로슈 아게 혈액 내 분석물 농도를 결정하는 방법 및 디바이스
US8920628B2 (en) 2012-11-02 2014-12-30 Roche Diagnostics Operations, Inc. Systems and methods for multiple analyte analysis
US8921061B2 (en) * 2012-11-02 2014-12-30 Roche Diagnostics Operations, Inc. Reagent materials and associated test elements
CN104870982B (zh) 2012-12-20 2019-02-15 霍夫曼-拉罗奇有限公司 用于评估医学测量曲线的方法
KR101750638B1 (ko) 2012-12-20 2017-06-23 에프. 호프만-라 로슈 아게 체액의 샘플을 분석하는 방법
EP2770064A1 (de) 2013-02-22 2014-08-27 F. Hoffmann-La Roche AG Hocheffiziente Herstellung von Blutglucose-Teststreifen
EP2781919A1 (en) 2013-03-19 2014-09-24 Roche Diagniostics GmbH Method / device for generating a corrected value of an analyte concentration in a sample of a body fluid
WO2014180939A1 (en) 2013-05-08 2014-11-13 Roche Diagnostics Gmbh Stabilization of enzymes by nicotinic acid
HK1213296A1 (zh) * 2013-06-04 2016-06-30 豪夫迈‧罗氏有限公司 用於fret的新化合物及与其相关的方法
EP2811299A1 (en) 2013-06-07 2014-12-10 Roche Diagniostics GmbH Test element for detecting at least one analyte in a body fluid
EP3063169B1 (en) 2013-10-29 2018-10-10 F. Hoffmann-La Roche AG Nano-enzyme containers for test elements
WO2015078899A1 (en) 2013-11-27 2015-06-04 Roche Diagnostics Gmbh Composition comprising up-converting phosphors for detecting an analyte
EP2927319A1 (en) 2014-03-31 2015-10-07 Roche Diagnostics GmbH High load enzyme immobilization by crosslinking
CA2945612C (en) 2014-04-14 2019-09-10 F. Hoffmann-La Roche Ag Phenazinium mediators
CN106687812A (zh) * 2014-08-05 2017-05-17 贝克顿·迪金森公司 用于分析血液样品中的葡萄糖‑6‑磷酸脱氢酶活性的方法和组合物
EP3183246B1 (en) 2014-08-22 2020-09-23 Roche Diagnostics GmbH Redoxindicators
ES2756714T3 (es) 2014-08-25 2020-04-27 Hoffmann La Roche Tira reactiva de dos electrodos que compensan la interferencia
CN108350439A (zh) 2015-12-21 2018-07-31 豪夫迈·罗氏有限公司 来自粪产碱菌的突变体3-羟基丁酸脱氢酶及其相关方法和用途
EP3414325B1 (en) 2016-02-09 2020-01-29 Roche Diabetes Care GmbH Mutant 3-hydroxybutyrate dehydrogenase from rhodobacter sphaeroides as well as methods and uses involving the same
CA3035874C (en) 2016-10-05 2025-09-09 F. Hoffmann-La Roche Ag DETECTION REAGENTS AND ELECTRODE ARRANGEMENTS FOR MULTI-ANALYTICAL DIAGNOSTIC TEST ELEMENTS, AS WELL AS THEIR METHODS OF USE
EP3339431A1 (en) 2016-12-22 2018-06-27 Roche Diabetes Care GmbH Glucose dehydrogenase variants with improved properties
CN107966555A (zh) * 2017-11-23 2018-04-27 中山市创艺生化工程有限公司 一种用于稳定保存nad或其衍生物的存储液
EP3759231B1 (en) 2018-02-28 2023-10-18 F. Hoffmann-La Roche AG Biocompatibility coating for continuous analyte measurement
CN111217744A (zh) * 2018-11-26 2020-06-02 中国科学院大连化学物理研究所 一种d-氨基酸基nad+类似物及其合成和应用
WO2022132963A1 (en) 2020-12-15 2022-06-23 Abbott Diabetes Care Inc. Nad(p) depot for nad(p)-dependent enzyme-based sensors
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Also Published As

Publication number Publication date
AU2006274140B2 (en) 2010-11-11
KR20080028507A (ko) 2008-03-31
US8809013B2 (en) 2014-08-19
CA2614792A1 (en) 2007-02-01
ES2461624T3 (es) 2014-05-20
EP2364989B1 (de) 2014-03-05
AU2011200465B2 (en) 2012-02-09
DK1907408T3 (da) 2014-06-10
US20140206024A1 (en) 2014-07-24
JP5129133B2 (ja) 2013-01-23
MX2008000946A (es) 2008-03-27
PT1907408E (pt) 2014-03-28
AU2006274140B8 (en) 2011-02-03
DK2364988T3 (da) 2014-05-26
US20160326567A1 (en) 2016-11-10
US20080213809A1 (en) 2008-09-04
ES2461266T3 (es) 2014-05-19
EP2364989A1 (de) 2011-09-14
PL2364988T3 (pl) 2014-08-29
CN103122371B (zh) 2016-12-28
SG187511A1 (en) 2013-02-28
KR101483829B1 (ko) 2015-01-16
PT2364988E (pt) 2014-04-03
CN103122371A (zh) 2013-05-29
JP5650695B2 (ja) 2015-01-07
ES2453150T3 (es) 2014-04-04
KR20120044372A (ko) 2012-05-07
KR101483899B1 (ko) 2015-01-16
JP2009502844A (ja) 2009-01-29
WO2007012494A1 (de) 2007-02-01
PT2364989E (pt) 2014-04-04
US9399790B2 (en) 2016-07-26
HK1123308A1 (en) 2009-06-12
PL1907408T3 (pl) 2014-07-31
US10167497B2 (en) 2019-01-01
JP2012224638A (ja) 2012-11-15
AU2011200465A1 (en) 2011-02-24
KR20110028522A (ko) 2011-03-18
KR20140003637A (ko) 2014-01-09
EP1907408B1 (de) 2014-03-05
EP2364988A1 (de) 2011-09-14
CN101233144A (zh) 2008-07-30
DK2364989T3 (da) 2014-06-10
KR101035524B1 (ko) 2011-05-23
DE102005035461A1 (de) 2007-02-15
AU2006274140A1 (en) 2007-02-01
EP2364988B1 (de) 2014-02-26
WO2007012494B1 (de) 2007-03-29
EP1907408A1 (de) 2008-04-09
CA2737123A1 (en) 2007-02-01
PL2364989T3 (pl) 2014-08-29
CA2614792C (en) 2011-07-12
CN101233144B (zh) 2013-02-06

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Legal Events

Date Code Title Description
B07D Technical examination (opinion) related to article 229 of industrial property law [chapter 7.4 patent gazette]
B07G Grant request does not fulfill article 229-c lpi (prior consent of anvisa) [chapter 7.7 patent gazette]
B08F Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette]
B08K Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette]

Free format text: EM VIRTUDE DO ARQUIVAMENTO PUBLICADO NA RPI 2472 DE 22-05-2018 E CONSIDERANDO AUSENCIA DE MANIFESTACAO DENTRO DOS PRAZOS LEGAIS, INFORMO QUE CABE SER MANTIDO O ARQUIVAMENTO DO PEDIDO DE PATENTE, CONFORME O DISPOSTO NO ARTIGO 12, DA RESOLUCAO 113/2013.