PL2364989T3 - Stabilne pochodne NAD/NADH - Google Patents

Stabilne pochodne NAD/NADH

Info

Publication number
PL2364989T3
PL2364989T3 PL11167476T PL11167476T PL2364989T3 PL 2364989 T3 PL2364989 T3 PL 2364989T3 PL 11167476 T PL11167476 T PL 11167476T PL 11167476 T PL11167476 T PL 11167476T PL 2364989 T3 PL2364989 T3 PL 2364989T3
Authority
PL
Poland
Prior art keywords
nadh
derivatives
stable nad
nad
stable
Prior art date
Application number
PL11167476T
Other languages
English (en)
Inventor
Joachim Hoenes
Dieter Heindl
Carina Horn
Claudia Gaessler-Dietsche
Original Assignee
Hoffmann La Roche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche
Publication of PL2364989T3 publication Critical patent/PL2364989T3/pl

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/26Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving oxidoreductase
    • C12Q1/32Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving oxidoreductase involving dehydrogenase
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/531Production of immunochemical test materials
    • G01N33/532Production of labelled immunochemicals
    • G01N33/533Production of labelled immunochemicals with fluorescent label

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Immunology (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • General Health & Medical Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • Biomedical Technology (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Cell Biology (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Saccharide Compounds (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
PL11167476T 2005-07-28 2006-07-28 Stabilne pochodne NAD/NADH PL2364989T3 (pl)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
DE102005035461A DE102005035461A1 (de) 2005-07-28 2005-07-28 Stabile NAD/NADH-Derivate
EP11167476.8A EP2364989B1 (de) 2005-07-28 2006-07-28 Stabile NAD/NADH-Derivate
EP06776486.0A EP1907408B1 (de) 2005-07-28 2006-07-28 Stabile nad/nadh-derivate

Publications (1)

Publication Number Publication Date
PL2364989T3 true PL2364989T3 (pl) 2014-08-29

Family

ID=37137552

Family Applications (3)

Application Number Title Priority Date Filing Date
PL06776486T PL1907408T3 (pl) 2005-07-28 2006-07-28 Stabilne pochodne NAD/NADH
PL11167471T PL2364988T3 (pl) 2005-07-28 2006-07-28 Stabilne pochodne NAD/NADH
PL11167476T PL2364989T3 (pl) 2005-07-28 2006-07-28 Stabilne pochodne NAD/NADH

Family Applications Before (2)

Application Number Title Priority Date Filing Date
PL06776486T PL1907408T3 (pl) 2005-07-28 2006-07-28 Stabilne pochodne NAD/NADH
PL11167471T PL2364988T3 (pl) 2005-07-28 2006-07-28 Stabilne pochodne NAD/NADH

Country Status (17)

Country Link
US (3) US8809013B2 (pl)
EP (3) EP2364989B1 (pl)
JP (2) JP5129133B2 (pl)
KR (4) KR20110028522A (pl)
CN (2) CN103122371B (pl)
AU (2) AU2006274140B8 (pl)
BR (1) BRPI0614217A2 (pl)
CA (2) CA2737123A1 (pl)
DE (1) DE102005035461A1 (pl)
DK (3) DK1907408T3 (pl)
ES (3) ES2461624T3 (pl)
HK (1) HK1123308A1 (pl)
MX (1) MX2008000946A (pl)
PL (3) PL1907408T3 (pl)
PT (3) PT2364988E (pl)
SG (1) SG187511A1 (pl)
WO (1) WO2007012494A1 (pl)

Families Citing this family (52)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE102005035461A1 (de) * 2005-07-28 2007-02-15 Roche Diagnostics Gmbh Stabile NAD/NADH-Derivate
US7553615B2 (en) * 2005-07-28 2009-06-30 Roche Diagnostics Operations, Inc. Compounds, methods, complexes, apparatuses and uses relating to stabile forms of NAD/NADH
EP2022859A1 (de) * 2007-08-01 2009-02-11 Roche Diagnostics GmbH Verfahren und Vorrichtung zur Bestimmung der Konzentration eines Analyten mittels Fluoreszenzmessung
CN101497638B (zh) * 2008-01-30 2012-09-26 中国科学院大连化学物理研究所 一种nad+类似物及其合成和应用
EP2093284A1 (de) * 2008-02-19 2009-08-26 F.Hoffmann-La Roche Ag Stabilisierung von Dehydrogenasen mit stabilen Coenzymen
CA2750474C (en) * 2009-02-19 2017-07-25 F. Hoffmann-La Roche Ag Fast reaction kinetics of enzymes having low activity in dry chemistry layers
EP2226007A1 (de) 2009-02-19 2010-09-08 Roche Diagnostics GmbH Testelementmagazin mit abgedeckten Testfeldern
EP2226008A1 (de) 2009-02-19 2010-09-08 Roche Diagnostics GmbH Verfahren zur Herstellung eines analytischen Magazins
CN102325496B (zh) * 2009-02-19 2015-10-07 霍夫曼-拉罗奇有限公司 分析辅助工具的节省空间的储存
EP2398909B1 (de) 2009-02-19 2015-07-22 F. Hoffmann-La Roche AG Schnelle reaktionskinetik von enzymen mit niedriger aktivität in trockenen chemieschichten
EP2459728B1 (en) 2009-07-27 2013-06-05 Roche Diagnostics GmbH Enzymatic synthesis of carba-NAD
CN102471274B (zh) * 2009-07-27 2016-08-03 霍夫曼-拉罗奇有限公司 用于制备n-取代的吡啶鎓化合物的方法和物质
JP5544423B2 (ja) 2009-07-27 2014-07-09 エフ・ホフマン−ラ・ロシュ・アクチェンゲゼルシャフト N置換ピリジニウム化合物の調製のための方法及び物質
EP2287605A1 (de) * 2009-08-20 2011-02-23 Roche Diagnostics GmbH Vereinfachte Magazinierung integrierter Systeme
EP2292751A1 (de) 2009-08-20 2011-03-09 Roche Diagnostics GmbH Stabilisierung von Enzymen mit stabilen Coenzymen
EP2333544A1 (de) 2009-12-11 2011-06-15 F. Hoffmann-La Roche AG Sterilisierbare Chemie für Testelemente
MX2012006706A (es) 2009-12-16 2012-07-03 Hoffmann La Roche Deteccion de la descomposicion de las enzimas en un elemento de prueba mediante la liberacion controlada de analito protegido.
KR101252351B1 (ko) * 2010-05-24 2013-04-08 동국대학교 산학협력단 전기효소적 합성 반응을 위한 nad(p) 유도체의 전기화학적 환원 방법
CN102453067B (zh) * 2010-10-29 2015-08-05 中国科学院大连化学物理研究所 一种nad+类似物的制备方法及其应用
CA2819989C (en) 2011-01-26 2019-03-12 Peter Gebauer Method and substances for preparation of n-substituted pyridinium compounds
CA2830997C (en) 2011-04-12 2018-06-26 F. Hoffmann-La Roche Ag Analytical aid
US9752990B2 (en) 2013-09-30 2017-09-05 Honeywell International Inc. Low-powered system for driving a fuel control mechanism
CN102863495A (zh) * 2011-07-06 2013-01-09 上海执诚生物科技股份有限公司 一种含有nad+或nadh的稳定的组合物
JP2014530208A (ja) 2011-09-28 2014-11-17 エフ ホフマン−ラ ロッシュ アクチェン ゲゼルシャフト アゾメディエーター
JP6128808B2 (ja) * 2011-11-15 2017-05-17 栄研化学株式会社 酵素活性の検出、測定方法およびこれを利用したキット
EP2620507A1 (en) 2012-01-25 2013-07-31 Roche Diagnostics GmbH Method for the evaluation of the quality of a test element
EP2636750A1 (en) 2012-03-06 2013-09-11 Roche Diagniostics GmbH Compatible solute ectoine as well as derivatives thereof for enzyme stabilization
CA2865678C (en) 2012-04-19 2018-03-13 Susanne BALDUS Method and device for determining an analyte concentration in blood
US8920628B2 (en) 2012-11-02 2014-12-30 Roche Diagnostics Operations, Inc. Systems and methods for multiple analyte analysis
US8921061B2 (en) * 2012-11-02 2014-12-30 Roche Diagnostics Operations, Inc. Reagent materials and associated test elements
CN104854457B (zh) 2012-12-20 2016-09-14 霍夫曼-拉罗奇有限公司 用于分析体液样本的方法
EP2936124B1 (en) 2012-12-20 2017-03-15 Roche Diabetes Care GmbH Methods for evaluating medical measurement curves
EP2770064A1 (de) 2013-02-22 2014-08-27 F. Hoffmann-La Roche AG Hocheffiziente Herstellung von Blutglucose-Teststreifen
EP2781919A1 (en) 2013-03-19 2014-09-24 Roche Diagniostics GmbH Method / device for generating a corrected value of an analyte concentration in a sample of a body fluid
WO2014180939A1 (en) 2013-05-08 2014-11-13 Roche Diagnostics Gmbh Stabilization of enzymes by nicotinic acid
EP3004372A1 (en) * 2013-06-04 2016-04-13 Roche Diagnostics GmbH Novel compounds useful for fret and methods related thereto
EP2811299A1 (en) 2013-06-07 2014-12-10 Roche Diagniostics GmbH Test element for detecting at least one analyte in a body fluid
EP3063169B1 (en) 2013-10-29 2018-10-10 F. Hoffmann-La Roche AG Nano-enzyme containers for test elements
WO2015078899A1 (en) 2013-11-27 2015-06-04 Roche Diagnostics Gmbh Composition comprising up-converting phosphors for detecting an analyte
EP2927319A1 (en) 2014-03-31 2015-10-07 Roche Diagnostics GmbH High load enzyme immobilization by crosslinking
CA2945612C (en) 2014-04-14 2019-09-10 F. Hoffmann-La Roche Ag Phenazinium mediators
SG11201700876RA (en) * 2014-08-05 2017-03-30 Becton Dickinson Co Methods and compositions for analyzing glucose-6-phosphate dehydrogenase activity in blood samples
JP6659669B2 (ja) 2014-08-22 2020-03-04 エフ.ホフマン−ラ ロシュ アーゲーF. Hoffmann−La Roche Aktiengesellschaft レドックス指示薬
ES2883115T3 (es) 2014-08-25 2021-12-07 Hoffmann La Roche Tira reactiva de dos electrodos que compensan la interferencia
CN108350439A (zh) 2015-12-21 2018-07-31 豪夫迈·罗氏有限公司 来自粪产碱菌的突变体3-羟基丁酸脱氢酶及其相关方法和用途
WO2017137491A1 (en) 2016-02-09 2017-08-17 Roche Diabetes Care Gmbh Mutant 3-hydroxybutyrate dehydrogenase from rhodobacter sphaeroides as well as methods and uses involving the same
KR102372113B1 (ko) 2016-10-05 2022-03-07 에프. 호프만-라 로슈 아게 다중 분석물 진단 테스트 엘리먼트들을 위한 검출 시약들 및 전극 배열들, 그리고 그것을 사용하는 방법들
EP3339431A1 (en) 2016-12-22 2018-06-27 Roche Diabetes Care GmbH Glucose dehydrogenase variants with improved properties
CN107966555A (zh) * 2017-11-23 2018-04-27 中山市创艺生化工程有限公司 一种用于稳定保存nad或其衍生物的存储液
EP3759231B1 (en) 2018-02-28 2023-10-18 F. Hoffmann-La Roche AG Biocompatibility coating for continuous analyte measurement
CN111217744A (zh) * 2018-11-26 2020-06-02 中国科学院大连化学物理研究所 一种d-氨基酸基nad+类似物及其合成和应用
WO2022132963A1 (en) 2020-12-15 2022-06-23 Abbott Diabetes Care Inc. Nad(p) depot for nad(p)-dependent enzyme-based sensors

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS437333Y1 (pl) 1965-07-08 1968-04-01
JPS53107486A (en) * 1977-02-28 1978-09-19 Wako Pure Chem Ind Ltd Stabilized nadh aqueous solution
JPS61274636A (ja) 1985-05-30 1986-12-04 西南自動車工業株式会社 活魚水槽
US5801006A (en) * 1997-02-04 1998-09-01 Specialty Assays, Inc. Use of NADPH and NADH analogs in the measurement of enzyme activities and metabolites
JP4260245B2 (ja) * 1998-06-25 2009-04-30 株式会社三菱化学ヤトロン 還元型ニコチンアミドアデニンジヌクレオチド類の分解を防止する方法及び分解防止用試薬
US6380380B1 (en) 1999-01-04 2002-04-30 Specialty Assays, Inc. Use of nicotinamide adenine dinucleotide (NAD) and nicotinamide adenine dinucliotide phosphate (NADP) analogs to measure enzyme activities metabolites and substrates
AU2001262702A1 (en) 2000-06-07 2001-12-17 Asahi Kasei Kabushiki Kaisha Coenzyme derivatives and enzymes appropriate therefor
DE10221845A1 (de) 2002-05-16 2003-11-27 Roche Diagnostics Gmbh Verfahren und Reagenzsystem mit nicht-regenerierbarem Enzym-Coenzym-Komplex
BR0309947B1 (pt) 2002-05-16 2013-11-26 Processo e dispositivo para produção de camadas de polímero sobre um suporte transparente, sua utilização e processo para produção de um sensor
DE102005035461A1 (de) * 2005-07-28 2007-02-15 Roche Diagnostics Gmbh Stabile NAD/NADH-Derivate

Also Published As

Publication number Publication date
CN101233144B (zh) 2013-02-06
JP2012224638A (ja) 2012-11-15
CA2737123A1 (en) 2007-02-01
PT1907408E (pt) 2014-03-28
US8809013B2 (en) 2014-08-19
CA2614792A1 (en) 2007-02-01
PL2364988T3 (pl) 2014-08-29
JP5129133B2 (ja) 2013-01-23
KR20110028522A (ko) 2011-03-18
AU2011200465A1 (en) 2011-02-24
KR20080028507A (ko) 2008-03-31
EP1907408A1 (de) 2008-04-09
EP2364989A1 (de) 2011-09-14
EP2364988A1 (de) 2011-09-14
JP5650695B2 (ja) 2015-01-07
WO2007012494A1 (de) 2007-02-01
DK2364989T3 (da) 2014-06-10
KR101035524B1 (ko) 2011-05-23
US20140206024A1 (en) 2014-07-24
KR101483899B1 (ko) 2015-01-16
PT2364988E (pt) 2014-04-03
KR101483829B1 (ko) 2015-01-16
ES2461624T3 (es) 2014-05-20
DE102005035461A1 (de) 2007-02-15
US10167497B2 (en) 2019-01-01
MX2008000946A (es) 2008-03-27
AU2006274140A1 (en) 2007-02-01
ES2461266T3 (es) 2014-05-19
PL1907408T3 (pl) 2014-07-31
CN103122371A (zh) 2013-05-29
CN101233144A (zh) 2008-07-30
US20160326567A1 (en) 2016-11-10
EP1907408B1 (de) 2014-03-05
DK1907408T3 (da) 2014-06-10
DK2364988T3 (da) 2014-05-26
CA2614792C (en) 2011-07-12
PT2364989E (pt) 2014-04-04
US9399790B2 (en) 2016-07-26
SG187511A1 (en) 2013-02-28
JP2009502844A (ja) 2009-01-29
EP2364988B1 (de) 2014-02-26
BRPI0614217A2 (pt) 2011-03-22
AU2011200465B2 (en) 2012-02-09
HK1123308A1 (en) 2009-06-12
AU2006274140B8 (en) 2011-02-03
US20080213809A1 (en) 2008-09-04
KR20140003637A (ko) 2014-01-09
AU2006274140B2 (en) 2010-11-11
KR20120044372A (ko) 2012-05-07
ES2453150T3 (es) 2014-04-04
CN103122371B (zh) 2016-12-28
EP2364989B1 (de) 2014-03-05
WO2007012494B1 (de) 2007-03-29

Similar Documents

Publication Publication Date Title
PL2364989T3 (pl) Stabilne pochodne NAD/NADH
DE502006001600D1 (en) Pyrazolylcarboxanilide
DE602006018441D1 (en) Arabinofuranosidasen
DE602006018627D1 (en) Cholesterol-absorptionsinhibitor
DE602006013270D1 (en) Prrs-impfstoffe
DE602006017073D1 (en) Aspartylproteasehemmer
DE602006016093D1 (en) Cyanoanthranilamidinsektizide
DK1866498T3 (en) C-profil
DE602006003064D1 (en) Tripeptid- und tetrapeptid-thioether
DE602006009835D1 (en) Nthalten
DE602006014261D1 (en) Benzimidazolverbindungen
DE602006016951D1 (en) 2-cyanoacrylatzusammensetzung
DE602006009492D1 (en) Fluidmaschinen
DE502005007477D1 (en) Delta-sigma-modulator
DE602006021065D1 (en) Lithium-batteriepack
DE602006021558D1 (en) Modulare montgomery-multiplikationseinrichtung
GB0506800D0 (en) New uses
DE502006002219D1 (en) Rotationspumpe
DE602006015303D1 (en) Lecknachweisflicken
DE502006004337D1 (en) Strangführungsrolle
DE502006007734D1 (en) Thiazolcarbonsäureanilide
GB2424168B (en) Stable aid
GB0613762D0 (en) Slabline structure
GB0522564D0 (en) Cells
GB0503644D0 (en) Catstep I