CN101233144B - 稳定的nad/nadh衍生物 - Google Patents

稳定的nad/nadh衍生物 Download PDF

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Publication number
CN101233144B
CN101233144B CN2006800273591A CN200680027359A CN101233144B CN 101233144 B CN101233144 B CN 101233144B CN 2006800273591 A CN2006800273591 A CN 2006800273591A CN 200680027359 A CN200680027359 A CN 200680027359A CN 101233144 B CN101233144 B CN 101233144B
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dehydrogenase
enzyme
glucose
case
independently represents
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CN101233144A (zh
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J·霍恩斯
D·海因德尔
C·霍恩
C·加斯勒-迪特谢
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F Hoffmann La Roche AG
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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/26—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving oxidoreductase
    • C12Q1/32—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving oxidoreductase involving dehydrogenase
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/531—Production of immunochemical test materials
    • G01N33/532—Production of labelled immunochemicals
    • G01N33/533—Production of labelled immunochemicals with fluorescent label

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  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
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  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • General Health & Medical Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • Biomedical Technology (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Cell Biology (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Saccharide Compounds (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
CN2006800273591A 2005-07-28 2006-07-28 稳定的nad/nadh衍生物 Active CN101233144B (zh)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN201210559220.9A CN103122371B (zh) 2005-07-28 2006-07-28 稳定的nad/nadh衍生物

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
DE102005035461.0 2005-07-28
DE102005035461A DE102005035461A1 (de) 2005-07-28 2005-07-28 Stabile NAD/NADH-Derivate
PCT/EP2006/007493 WO2007012494A1 (de) 2005-07-28 2006-07-28 Stabile nad/nadh-derivate

Related Child Applications (1)

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CN201210559220.9A Division CN103122371B (zh) 2005-07-28 2006-07-28 稳定的nad/nadh衍生物

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CN101233144A CN101233144A (zh) 2008-07-30
CN101233144B true CN101233144B (zh) 2013-02-06

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CN2006800273591A Active CN101233144B (zh) 2005-07-28 2006-07-28 稳定的nad/nadh衍生物
CN201210559220.9A Active CN103122371B (zh) 2005-07-28 2006-07-28 稳定的nad/nadh衍生物

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Country Link
US (3) US8809013B2 (https=)
EP (3) EP1907408B1 (https=)
JP (2) JP5129133B2 (https=)
KR (4) KR101035524B1 (https=)
CN (2) CN101233144B (https=)
AU (2) AU2006274140B8 (https=)
BR (1) BRPI0614217A2 (https=)
CA (2) CA2614792C (https=)
DE (1) DE102005035461A1 (https=)
DK (3) DK1907408T3 (https=)
ES (3) ES2461624T3 (https=)
MX (1) MX2008000946A (https=)
PL (3) PL2364988T3 (https=)
PT (3) PT2364989E (https=)
SG (1) SG187511A1 (https=)
WO (1) WO2007012494A1 (https=)

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CA2750474C (en) 2009-02-19 2017-07-25 F. Hoffmann-La Roche Ag Fast reaction kinetics of enzymes having low activity in dry chemistry layers
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CN102471793B (zh) * 2009-07-27 2014-04-30 霍夫曼-拉罗奇有限公司 Carba-nad的酶促合成
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CN102453067B (zh) * 2010-10-29 2015-08-05 中国科学院大连化学物理研究所 一种nad+类似物的制备方法及其应用
EP2668161B1 (en) 2011-01-26 2014-11-26 Roche Diagniostics GmbH Method and substances for preparation of n-substituted pyridinium compounds
CN104905799B (zh) 2011-04-12 2018-06-08 霍夫曼-拉罗奇有限公司 分析辅件
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CN102863495A (zh) * 2011-07-06 2013-01-09 上海执诚生物科技股份有限公司 一种含有nad+或nadh的稳定的组合物
KR101609083B1 (ko) 2011-09-28 2016-04-04 에프. 호프만-라 로슈 아게 아조 매개체
JP6128808B2 (ja) * 2011-11-15 2017-05-17 栄研化学株式会社 酵素活性の検出、測定方法およびこれを利用したキット
EP2620507A1 (en) 2012-01-25 2013-07-31 Roche Diagnostics GmbH Method for the evaluation of the quality of a test element
EP2636750A1 (en) 2012-03-06 2013-09-11 Roche Diagniostics GmbH Compatible solute ectoine as well as derivatives thereof for enzyme stabilization
CA2865678C (en) 2012-04-19 2018-03-13 Susanne BALDUS Method and device for determining an analyte concentration in blood
US8921061B2 (en) * 2012-11-02 2014-12-30 Roche Diagnostics Operations, Inc. Reagent materials and associated test elements
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CN104854457B (zh) 2012-12-20 2016-09-14 霍夫曼-拉罗奇有限公司 用于分析体液样本的方法
HUE034313T2 (en) 2012-12-20 2018-02-28 Hoffmann La Roche Procedures for evaluating medical measurement curves
EP2770064A1 (de) 2013-02-22 2014-08-27 F. Hoffmann-La Roche AG Hocheffiziente Herstellung von Blutglucose-Teststreifen
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HK1213296A1 (zh) * 2013-06-04 2016-06-30 豪夫迈‧罗氏有限公司 用於fret的新化合物及与其相关的方法
EP2811299A1 (en) 2013-06-07 2014-12-10 Roche Diagniostics GmbH Test element for detecting at least one analyte in a body fluid
WO2015063025A1 (en) 2013-10-29 2015-05-07 F. Hoffmann-La Roche Ag Nano-enzyme containers for test elements
EP3074524B1 (en) 2013-11-27 2019-11-06 Roche Diabetes Care GmbH Composition comprising up-converting phosphors for detecting an analyte
EP2927319A1 (en) 2014-03-31 2015-10-07 Roche Diagnostics GmbH High load enzyme immobilization by crosslinking
EP3131882B1 (en) 2014-04-14 2020-07-15 Roche Diagnostics GmbH Phenazinium mediators
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EP3757096B1 (en) 2014-08-22 2025-03-12 Roche Diagnostics GmbH Redoxindicators for a use in cell viability testing
BR112017001444B1 (pt) 2014-08-25 2022-08-16 F. Hoffmann-La Roche Ag Método para detectar pelo menos um analito em uma amostra de teste, elemento sensor, dispositivo de teste, sistema de teste, uso do elemento sensor e portador de dados
EP3394252B1 (en) 2015-12-21 2020-04-29 F. Hoffmann-La Roche AG Mutant 3-hydroxybutyrate dehydrogenase from alcaligenes faecalis as well as methods and uses involving the same
ES2782199T3 (es) 2016-02-09 2020-09-11 Hoffmann La Roche 3-Hidroxibutirato deshidrogenasa mutante de Rhodobacter sphaeroides, así como procedimientos y usos que implican la misma
KR102372113B1 (ko) 2016-10-05 2022-03-07 에프. 호프만-라 로슈 아게 다중 분석물 진단 테스트 엘리먼트들을 위한 검출 시약들 및 전극 배열들, 그리고 그것을 사용하는 방법들
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CN107966555A (zh) * 2017-11-23 2018-04-27 中山市创艺生化工程有限公司 一种用于稳定保存nad或其衍生物的存储液
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Also Published As

Publication number Publication date
DE102005035461A1 (de) 2007-02-15
PT2364988E (pt) 2014-04-03
US8809013B2 (en) 2014-08-19
CA2614792C (en) 2011-07-12
PL2364988T3 (pl) 2014-08-29
CN101233144A (zh) 2008-07-30
DK1907408T3 (da) 2014-06-10
US20140206024A1 (en) 2014-07-24
JP5650695B2 (ja) 2015-01-07
ES2453150T3 (es) 2014-04-04
KR101035524B1 (ko) 2011-05-23
AU2006274140B8 (en) 2011-02-03
DK2364989T3 (da) 2014-06-10
WO2007012494B1 (de) 2007-03-29
KR101483829B1 (ko) 2015-01-16
US20160326567A1 (en) 2016-11-10
CA2614792A1 (en) 2007-02-01
PL2364989T3 (pl) 2014-08-29
EP2364988A1 (de) 2011-09-14
US20080213809A1 (en) 2008-09-04
US10167497B2 (en) 2019-01-01
JP5129133B2 (ja) 2013-01-23
EP1907408A1 (de) 2008-04-09
CA2737123A1 (en) 2007-02-01
MX2008000946A (es) 2008-03-27
EP1907408B1 (de) 2014-03-05
DK2364988T3 (da) 2014-05-26
EP2364989A1 (de) 2011-09-14
BRPI0614217A2 (pt) 2011-03-22
PT2364989E (pt) 2014-04-04
US9399790B2 (en) 2016-07-26
HK1123308A1 (en) 2009-06-12
ES2461624T3 (es) 2014-05-20
KR101483899B1 (ko) 2015-01-16
AU2011200465A1 (en) 2011-02-24
SG187511A1 (en) 2013-02-28
AU2006274140A1 (en) 2007-02-01
CN103122371B (zh) 2016-12-28
KR20140003637A (ko) 2014-01-09
PT1907408E (pt) 2014-03-28
PL1907408T3 (pl) 2014-07-31
AU2011200465B2 (en) 2012-02-09
CN103122371A (zh) 2013-05-29
EP2364989B1 (de) 2014-03-05
KR20120044372A (ko) 2012-05-07
JP2012224638A (ja) 2012-11-15
WO2007012494A1 (de) 2007-02-01
AU2006274140B2 (en) 2010-11-11
JP2009502844A (ja) 2009-01-29
KR20110028522A (ko) 2011-03-18
KR20080028507A (ko) 2008-03-31
EP2364988B1 (de) 2014-02-26
ES2461266T3 (es) 2014-05-19

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