ES2460022T3 - Nuevos procedimientos de producción de derivados de benzofenona - Google Patents

Nuevos procedimientos de producción de derivados de benzofenona Download PDF

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Publication number
ES2460022T3
ES2460022T3 ES11702677.3T ES11702677T ES2460022T3 ES 2460022 T3 ES2460022 T3 ES 2460022T3 ES 11702677 T ES11702677 T ES 11702677T ES 2460022 T3 ES2460022 T3 ES 2460022T3
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ES
Spain
Prior art keywords
compound
formula
solvent
reaction
preparing
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
ES11702677.3T
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English (en)
Spanish (es)
Inventor
Lars Eklund
Jonas Nilsson
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Nobel Chemicals AB
Original Assignee
Cambrex Karlskoga AB
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
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First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=43827282&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ES2460022(T3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Cambrex Karlskoga AB filed Critical Cambrex Karlskoga AB
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Publication of ES2460022T3 publication Critical patent/ES2460022T3/es
Active legal-status Critical Current
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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C41/00—Preparation of ethers; Preparation of compounds having groups, groups or groups
    • C07C41/01—Preparation of ethers
    • C07C41/18—Preparation of ethers by reactions not forming ether-oxygen bonds
    • C07C41/30—Preparation of ethers by reactions not forming ether-oxygen bonds by increasing the number of carbon atoms, e.g. by oligomerisation
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/12—Drugs for genital or sexual disorders; Contraceptives for climacteric disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
    • A61P5/30—Oestrogens
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/61—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups
    • C07C45/67—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton
    • C07C45/68—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms
    • C07C45/72—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms by reaction of compounds containing >C = O groups with the same or other compounds containing >C = O groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • Endocrinology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Diabetes (AREA)
  • Reproductive Health (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
ES11702677.3T 2010-01-19 2011-01-19 Nuevos procedimientos de producción de derivados de benzofenona Active ES2460022T3 (es)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US29609610P 2010-01-19 2010-01-19
US296096P 2010-01-19
PCT/GB2011/000058 WO2011089385A1 (en) 2010-01-19 2011-01-19 New processes for producing benzophenone derivatives

Publications (1)

Publication Number Publication Date
ES2460022T3 true ES2460022T3 (es) 2014-05-13

Family

ID=43827282

Family Applications (1)

Application Number Title Priority Date Filing Date
ES11702677.3T Active ES2460022T3 (es) 2010-01-19 2011-01-19 Nuevos procedimientos de producción de derivados de benzofenona

Country Status (13)

Country Link
US (1) US9085519B2 (enExample)
EP (1) EP2526080B1 (enExample)
JP (1) JP5850857B2 (enExample)
CN (1) CN102770402B (enExample)
BR (1) BR112012017845A2 (enExample)
DK (1) DK2526080T3 (enExample)
ES (1) ES2460022T3 (enExample)
HR (1) HRP20140558T1 (enExample)
PL (1) PL2526080T3 (enExample)
PT (1) PT2526080E (enExample)
RS (1) RS53353B (enExample)
SI (1) SI2526080T1 (enExample)
WO (1) WO2011089385A1 (enExample)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20150321983A1 (en) 2012-10-19 2015-11-12 Fermion Oy A process for the preparation of ospemifene
JP6174156B2 (ja) 2012-10-19 2017-08-02 フェルミオン オサケ ユキチュア オスペミフェンの製造方法
CN104030896A (zh) * 2013-03-07 2014-09-10 天津药物研究院 一种简易去除欧司哌米芬特异杂质的方法
KR20170054417A (ko) * 2014-09-16 2017-05-17 시오노기 앤드 컴파니, 리미티드 트라이페닐뷰텐 유도체의 제조 방법
CA2972198C (en) 2014-12-29 2023-05-09 Olon S.P.A. Process for the preparation of ospemifene and fispemifene
WO2016110805A1 (en) * 2015-01-09 2016-07-14 Glenmark Pharmaceuticals Limited Process for preparation of ospemifene
CN108368020A (zh) * 2015-12-15 2018-08-03 巴斯夫欧洲公司 羟基二苯甲酮聚乙二醇醚(甲基)丙烯酸酯的制备方法
KR102377433B1 (ko) * 2016-03-15 2022-03-23 시오노기 앤드 컴파니, 리미티드 페녹시에탄올 유도체의 제조 방법

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2182786A (en) 1938-09-14 1939-12-12 Dow Chemical Co Hydroxy-alkyl ethers of benzophenone
US2831768A (en) 1956-01-19 1958-04-22 Eastman Kodak Co Polymeric light-sensitive photographic elements
CS196471B1 (cs) 1977-11-28 1980-03-31 Ivan Lukac Nové p-acylované fenoxyetanoly
EP0072475B1 (de) 1981-08-17 1986-08-20 F. HOFFMANN-LA ROCHE & CO. Aktiengesellschaft Carbaminsäureester, Verfahren zu deren Herstellung, Schädlingsbekämpfungsmittel, die diese Verbindungen als Wirkstoffe enthalten, sowie Verwendung solcher Verbindungen und Mittel zur Bekämpfung von Schädlingen
GB2126576B (en) 1982-06-25 1985-06-19 Farmos Group Limited Alkane and alkene derivatives
US4625048A (en) * 1982-08-13 1986-11-25 Hoffmann-La Roche Inc. Carbamic acid esters
DE3814781A1 (de) * 1988-04-30 1989-11-09 Basf Ag Verfahren zur herstellung von 2-hydroxy-4-(2'-hydroxyethoxy)-benzophenonen
DE3936592A1 (de) 1989-11-03 1991-05-08 Basf Ag Verfahren zur herstellung und reinigung von 2-hydroxy-4-(2'-hydroxy-ethoxy)phenylarylketonen
GB9418067D0 (en) 1994-09-07 1994-10-26 Orion Yhtymae Oy Triphenylethylenes for the prevention and treatment of osteoporosis
GB9803521D0 (en) 1998-02-19 1998-04-15 Orion Yhtymo Oy New compounds and pharmaceutical compositions thereof
TW593256B (en) * 1999-11-16 2004-06-21 Hormos Medical Oy Ltd Triphenylalkene derivatives and their use as selective estrogen receptor modulators
JP2003522810A (ja) 2000-02-17 2003-07-29 アップルトン ペーパーズ インコーポレイテッド アルコキシ又はアリルメトキシエタンの製造方法
PT2121553E (pt) * 2007-02-14 2012-07-26 Hormos Medical Ltd Método para a preparação de derivados de trifenilbuteno com valor terapêutico
WO2008099060A2 (en) 2007-02-14 2008-08-21 Hormos Medical Ltd Methods for the preparation of fispemifene from ospemifene

Also Published As

Publication number Publication date
US20130035514A1 (en) 2013-02-07
PT2526080E (pt) 2014-05-06
WO2011089385A1 (en) 2011-07-28
HRP20140558T1 (hr) 2014-08-01
HK1179244A1 (en) 2013-09-27
EP2526080B1 (en) 2014-03-26
CN102770402A (zh) 2012-11-07
RS53353B (sr) 2014-10-31
SI2526080T1 (sl) 2014-07-31
DK2526080T3 (da) 2014-04-28
US9085519B2 (en) 2015-07-21
PL2526080T3 (pl) 2014-08-29
BR112012017845A2 (pt) 2016-03-29
EP2526080A1 (en) 2012-11-28
JP5850857B2 (ja) 2016-02-03
JP2013517320A (ja) 2013-05-16
CN102770402B (zh) 2016-01-20

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