ES2402220T3 - Compuestos de 3-isobutil-9,10-dimetoxi-1,3,4,6,7,11b-hexahidro-2H-pirido[2,1-a]isoquinolin-2-ol sustituidos y métodos relacionados con los mismos - Google Patents

Compuestos de 3-isobutil-9,10-dimetoxi-1,3,4,6,7,11b-hexahidro-2H-pirido[2,1-a]isoquinolin-2-ol sustituidos y métodos relacionados con los mismos Download PDF

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Publication number
ES2402220T3
ES2402220T3 ES07864160T ES07864160T ES2402220T3 ES 2402220 T3 ES2402220 T3 ES 2402220T3 ES 07864160 T ES07864160 T ES 07864160T ES 07864160 T ES07864160 T ES 07864160T ES 2402220 T3 ES2402220 T3 ES 2402220T3
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Spain
Prior art keywords
compound
isoquinolin
isobutyl
pyrido
dimethoxy
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Active
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ES07864160T
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English (en)
Spanish (es)
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ES2402220T8 (es
Inventor
Kyle W. Gano
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Neurocrine Biosciences Inc
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Neurocrine Biosciences Inc
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Application filed by Neurocrine Biosciences Inc filed Critical Neurocrine Biosciences Inc
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Publication of ES2402220T3 publication Critical patent/ES2402220T3/es
Publication of ES2402220T8 publication Critical patent/ES2402220T8/es
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Psychology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
ES07864160T 2006-11-08 2007-11-08 Compuestos de 3-isobutil-9,10-dimetoxi-1,3,4,6,7,11b-hexahidro-2H-pirido[2,1-a]isoquinolin-2-ol sustituidos y métodos relacionados con los mismos Active ES2402220T3 (es)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US86494406P 2006-11-08 2006-11-08
US864944P 2006-11-08
PCT/US2007/084176 WO2008058261A1 (en) 2006-11-08 2007-11-08 Substituted 3-isobutyl-9, 10-dimethoxy-1,3,4,6,7,11b-hexahydro-2h-pyrido[2,1-a] isoquinolin-2-ol compounds and methods relating thereto

Publications (2)

Publication Number Publication Date
ES2402220T3 true ES2402220T3 (es) 2013-04-29
ES2402220T8 ES2402220T8 (es) 2021-12-23

Family

ID=39110526

Family Applications (1)

Application Number Title Priority Date Filing Date
ES07864160T Active ES2402220T3 (es) 2006-11-08 2007-11-08 Compuestos de 3-isobutil-9,10-dimetoxi-1,3,4,6,7,11b-hexahidro-2H-pirido[2,1-a]isoquinolin-2-ol sustituidos y métodos relacionados con los mismos

Country Status (16)

Country Link
US (2) US8039627B2 (enExample)
EP (1) EP2081929B1 (enExample)
JP (1) JP5290185B2 (enExample)
KR (1) KR101500766B1 (enExample)
CN (1) CN101553487B (enExample)
AU (1) AU2007317242B2 (enExample)
BR (1) BRPI0718247B1 (enExample)
CA (1) CA2668689C (enExample)
DK (1) DK2081929T3 (enExample)
EA (1) EA018378B1 (enExample)
ES (1) ES2402220T3 (enExample)
IL (1) IL198250A0 (enExample)
MX (1) MX2009004910A (enExample)
PL (1) PL2081929T3 (enExample)
PT (1) PT2081929E (enExample)
WO (1) WO2008058261A1 (enExample)

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Also Published As

Publication number Publication date
EP2081929A1 (en) 2009-07-29
US20080167337A1 (en) 2008-07-10
KR101500766B1 (ko) 2015-03-16
US8357697B2 (en) 2013-01-22
CN101553487B (zh) 2012-06-13
PT2081929E (pt) 2013-04-15
DK2081929T3 (da) 2013-04-15
IL198250A0 (en) 2009-12-24
JP5290185B2 (ja) 2013-09-18
CN101553487A (zh) 2009-10-07
KR20090079257A (ko) 2009-07-21
MX2009004910A (es) 2009-07-24
AU2007317242B2 (en) 2013-08-01
EP2081929B1 (en) 2013-01-09
WO2008058261A1 (en) 2008-05-15
JP2010509366A (ja) 2010-03-25
CA2668689C (en) 2015-12-29
EA200970461A1 (ru) 2009-12-30
US8039627B2 (en) 2011-10-18
BRPI0718247A2 (pt) 2014-01-07
KR101500766B9 (ko) 2024-09-25
BRPI0718247B1 (pt) 2021-09-21
AU2007317242A1 (en) 2008-05-15
CA2668689A1 (en) 2008-05-15
US20120077839A1 (en) 2012-03-29
ES2402220T8 (es) 2021-12-23
PL2081929T3 (pl) 2013-06-28
EA018378B1 (ru) 2013-07-30

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