KR101500766B1 - 치환된 3-이소부틸-9,10-디메톡시-1,3,4,6,7,11ｂ-헥사히드로-2Ｈ-피리도[2,1-ａ]이소퀴놀린-2-올 화합물 및 그와 관련된 방법 - Google Patents

치환된 3-이소부틸-9,10-디메톡시-1,3,4,6,7,11ｂ-헥사히드로-2Ｈ-피리도[2,1-ａ]이소퀴놀린-2-올 화합물 및 그와 관련된 방법 Download PDF

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KR101500766B1
KR101500766B1 KR1020097011731A KR20097011731A KR101500766B1 KR 101500766 B1 KR101500766 B1 KR 101500766B1 KR 1020097011731 A KR1020097011731 A KR 1020097011731A KR 20097011731 A KR20097011731 A KR 20097011731A KR 101500766 B1 KR101500766 B1 KR 101500766B1
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dimethoxy
isobutyl
hexahydro
pyrido
isoquinolin
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KR20090079257A (ko
KR101500766B9 (ko
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카일 더블유. 가노
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뉴로크린 바이오사이언시즈 인코퍼레이티드
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Psychology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
KR1020097011731A 2006-11-08 2007-11-08 치환된 3-이소부틸-9,10-디메톡시-1,3,4,6,7,11ｂ-헥사히드로-2Ｈ-피리도[2,1-ａ]이소퀴놀린-2-올 화합물 및 그와 관련된 방법 Active KR101500766B1 (ko)

Applications Claiming Priority (3)

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US86494406P 2006-11-08 2006-11-08
US60/864,944 2006-11-08
PCT/US2007/084176 WO2008058261A1 (en) 2006-11-08 2007-11-08 Substituted 3-isobutyl-9, 10-dimethoxy-1,3,4,6,7,11b-hexahydro-2h-pyrido[2,1-a] isoquinolin-2-ol compounds and methods relating thereto

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KR20090079257A KR20090079257A (ko) 2009-07-21
KR101500766B1 true KR101500766B1 (ko) 2015-03-16
KR101500766B9 KR101500766B9 (ko) 2024-09-25

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US (2) US8039627B2 (enExample)
EP (1) EP2081929B1 (enExample)
JP (1) JP5290185B2 (enExample)
KR (1) KR101500766B1 (enExample)
CN (1) CN101553487B (enExample)
AU (1) AU2007317242B2 (enExample)
BR (1) BRPI0718247B1 (enExample)
CA (1) CA2668689C (enExample)
DK (1) DK2081929T3 (enExample)
EA (1) EA018378B1 (enExample)
ES (1) ES2402220T3 (enExample)
IL (1) IL198250A0 (enExample)
MX (1) MX2009004910A (enExample)
PL (1) PL2081929T3 (enExample)
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ES2402220T8 (es) 2021-12-23
EA018378B1 (ru) 2013-07-30
BRPI0718247B1 (pt) 2021-09-21
US8357697B2 (en) 2013-01-22
BRPI0718247A2 (pt) 2014-01-07
KR20090079257A (ko) 2009-07-21
AU2007317242B2 (en) 2013-08-01
US20120077839A1 (en) 2012-03-29
CN101553487A (zh) 2009-10-07
PL2081929T3 (pl) 2013-06-28
DK2081929T3 (da) 2013-04-15
EP2081929A1 (en) 2009-07-29
CN101553487B (zh) 2012-06-13
US8039627B2 (en) 2011-10-18
JP2010509366A (ja) 2010-03-25
KR101500766B9 (ko) 2024-09-25
CA2668689C (en) 2015-12-29
CA2668689A1 (en) 2008-05-15
WO2008058261A1 (en) 2008-05-15
EP2081929B1 (en) 2013-01-09
ES2402220T3 (es) 2013-04-29
JP5290185B2 (ja) 2013-09-18
EA200970461A1 (ru) 2009-12-30
AU2007317242A1 (en) 2008-05-15
IL198250A0 (en) 2009-12-24
MX2009004910A (es) 2009-07-24
PT2081929E (pt) 2013-04-15
US20080167337A1 (en) 2008-07-10

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