ES2396795T8 - Compuesto de sulfonamida y cristal del mismo - Google Patents

Compuesto de sulfonamida y cristal del mismo Download PDF

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Publication number
ES2396795T8
ES2396795T8 ES08790119T ES08790119T ES2396795T8 ES 2396795 T8 ES2396795 T8 ES 2396795T8 ES 08790119 T ES08790119 T ES 08790119T ES 08790119 T ES08790119 T ES 08790119T ES 2396795 T8 ES2396795 T8 ES 2396795T8
Authority
ES
Spain
Prior art keywords
sulfonamide
crystal compound
crystal
compound
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
ES08790119T
Other languages
English (en)
Other versions
ES2396795T3 (es
Inventor
Hitoshi Kida
Koki Matsubara
Shunsuke Kaneko
Yoshihito Kanzawa
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Asahi Kasei Pharma Corp
Original Assignee
Asahi Kasei Pharma Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Asahi Kasei Pharma Corp filed Critical Asahi Kasei Pharma Corp
Application granted granted Critical
Publication of ES2396795T3 publication Critical patent/ES2396795T3/es
Publication of ES2396795T8 publication Critical patent/ES2396795T8/es
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A61K31/472—Non-condensed isoquinolines, e.g. papaverine
    • A61K31/4725—Non-condensed isoquinolines, e.g. papaverine containing further heterocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A61P27/06—Antiglaucoma agents or miotics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Ophthalmology & Optometry (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
ES08790119T 2007-07-02 2008-07-01 Compuesto de sulfonamida y cirstal del mismo Active ES2396795T3 (es)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
JP2007174323 2007-07-02
JP2007174323 2007-07-02
US3422208P 2008-03-06 2008-03-06
US34222 2008-03-06
PCT/JP2008/001720 WO2009004792A1 (ja) 2007-07-02 2008-07-01 スルホンアミド化合物及びその結晶

Publications (2)

Publication Number Publication Date
ES2396795T3 ES2396795T3 (es) 2013-02-27
ES2396795T8 true ES2396795T8 (es) 2013-03-13

Family

ID=40225857

Family Applications (1)

Application Number Title Priority Date Filing Date
ES08790119T Active ES2396795T3 (es) 2007-07-02 2008-07-01 Compuesto de sulfonamida y cirstal del mismo

Country Status (10)

Country Link
US (2) US8232292B2 (es)
EP (1) EP2179997B1 (es)
JP (2) JP5234825B2 (es)
KR (1) KR101246392B1 (es)
CN (1) CN101730690B (es)
AU (1) AU2008272396B2 (es)
CA (1) CA2690753C (es)
ES (1) ES2396795T3 (es)
HK (1) HK1141028A1 (es)
WO (1) WO2009004792A1 (es)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8415372B2 (en) * 2007-02-27 2013-04-09 Asahi Kasei Pharma Corporation Sulfonamide compound
AU2008220104B2 (en) * 2007-02-28 2012-09-27 Asahi Kasei Pharma Corporation Sulfonamide derivative
CN101730690B (zh) * 2007-07-02 2013-01-16 旭化成制药株式会社 磺酰胺化合物及其结晶
EP2319514A4 (en) * 2008-07-25 2011-11-02 Asahi Kasei Pharma Corp STABLE AQUEOUS SOLUTION COMPOSITION COMPRISING A SULFONAMIDE COMPOUND
WO2015165341A1 (zh) * 2014-04-28 2015-11-05 南京明德新药研发股份有限公司 作为rho激酶抑制剂的异喹啉磺酰衍生物
WO2019015608A1 (zh) * 2017-07-19 2019-01-24 南京明德新药研发股份有限公司 异喹啉磺酰衍生物及其应用
JP7425482B2 (ja) 2018-12-17 2024-01-31 株式会社デ・ウエスタン・セラピテクス研究所 イソキノリンスルホンアミドの新規な形態
JPWO2020129877A1 (ja) * 2018-12-18 2021-10-28 株式会社デ・ウエスタン・セラピテクス研究所 イソキノリンスルホニルクロリド酸付加塩及びその製造方法

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* Cited by examiner, † Cited by third party
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US4456757A (en) 1981-03-20 1984-06-26 Asahi Kasei Kogyo Kabushiki Kaisha Isoquinolinesulfonyl derivatives and process for the preparation thereof
JPS57200366A (en) * 1981-06-01 1982-12-08 Asahi Chem Ind Co Ltd Isoquinoline compound
JPH0667926B2 (ja) 1985-11-12 1994-08-31 旭化成工業株式会社 環状のイソキノリンスルホンアミド誘導体
US5245034A (en) * 1988-12-26 1993-09-14 Kiroyoshi Hidaka Compound having vessel smooth muscle relaxation activity
US5216150A (en) * 1988-12-26 1993-06-01 Hiroyoshi Hidaka Derivatives of isoquinoline (and naphthalene) sulfonamides
JP2886225B2 (ja) * 1988-12-26 1999-04-26 弘義 日高 アルキレンジアミン誘導体及びその製造方法
CA2005741C (en) * 1988-12-26 1998-06-02 Hiroyoshi Hidaka Quinoline sulfonoamino compounds having vessel smooth muscle relaxation activity
JP3408546B2 (ja) 1991-02-19 2003-05-19 旭化成株式会社 抗喘息剤
FR2679907B1 (fr) 1991-07-31 1995-01-20 Adir Nouveaux n-[(isoquinolein-5 yl)sulfonyl] azacycloalcanes, leur procede de preparation et les compositions pharmaceutiques les contenant.
JP3176619B2 (ja) 1991-09-05 2001-06-18 ファルノ−ヴェトロファルム ゲゼルシャフト ミット ベシュレンクテル ハフツング 芳香族スルホンアミド化合物、阻害剤及びそれを含有する医薬組成物
JPH06100540A (ja) * 1992-09-24 1994-04-12 Asahi Chem Ind Co Ltd ５−イソキノリンスルホン酸アミド誘導体
AU720326B2 (en) * 1995-12-21 2000-05-25 Alcon Laboratories, Inc. Use of certain isoquinolinesulfonyl compounds for the treatment of glaucoma and ocular ischemia
CA2240271C (en) 1995-12-21 2005-12-13 Alcon Laboratories, Inc. Use of certain isoquinolinesulfonyl compounds for the treatment of glaucoma and ocular ischemia
JP3834663B2 (ja) 1996-02-02 2006-10-18 株式会社デ・ウエスタン・セラピテクス研究所 イソキノリン誘導体及び医薬
JPH1087491A (ja) * 1996-07-26 1998-04-07 Asahi Chem Ind Co Ltd 転写調節因子阻害剤
CA2263425C (en) 1996-08-12 2008-09-30 Yoshitomi Pharmaceutical Industries Ltd. Pharmaceutical agent containing rho kinase inhibitor
JP4316794B2 (ja) 1997-10-22 2009-08-19 株式会社デ・ウエスタン・セラピテクス研究所 イソキノリン誘導体及び医薬
EP1074545A4 (en) 1998-04-23 2001-08-22 Hiroyoshi Hidaka ISOCHINOLINE SULPHONAMIDE DERIVATIVES AND MEDICINES CONTAINING IT AS AN ACTIVE INGREDIENT
JP4212149B2 (ja) 1998-06-11 2009-01-21 株式会社デ・ウエスタン・セラピテクス研究所 医薬
US7217722B2 (en) 2000-02-01 2007-05-15 Kirin Beer Kabushiki Kaisha Nitrogen-containing compounds having kinase inhibitory activity and drugs containing the same
TWI336328B (en) 2001-03-23 2011-01-21 Bayer Healthcare Llc Rho-kinase inhibitors
HN2002000067A (es) 2001-03-23 2003-10-24 Bayer Healthcare Llc Inhibidores de la rho - quinasa.
WO2002100833A1 (fr) 2001-06-12 2002-12-19 Sumitomo Pharmaceuticals Company, Limited Inhibiteurs de rho kinase
US7094789B2 (en) * 2002-07-22 2006-08-22 Asahi Kasei Pharma Corporation 5-substituted isoquinoline derivatives
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MY139797A (en) * 2004-11-29 2009-10-30 Kowa Co (s)-(-)-1-(4-fluoroisoquinolin-5-yl)sulfonyl-2-methyl-1, 4-homopiperazine hydrochloride dihydrate
JP5140577B2 (ja) * 2005-03-31 2013-02-06 タケダ カリフォルニア インコーポレイテッド ヒドロキシステロイドデヒドロゲナーゼ阻害剤
WO2006115244A1 (ja) * 2005-04-25 2006-11-02 D. Western Therapeutics Institute, Inc. ４－ブロモイソキノリン誘導体及びこれを含有する医薬
WO2006115245A1 (ja) 2005-04-25 2006-11-02 D. Western Therapeutics Institute, Inc. ４－エチニルイソキノリン誘導体及びこれを含有する医薬
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JP2006348028A (ja) 2005-05-19 2006-12-28 Kowa Co 緑内障予防又は治療剤
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US8415372B2 (en) 2007-02-27 2013-04-09 Asahi Kasei Pharma Corporation Sulfonamide compound
AU2008220104B2 (en) * 2007-02-28 2012-09-27 Asahi Kasei Pharma Corporation Sulfonamide derivative
CN101730690B (zh) * 2007-07-02 2013-01-16 旭化成制药株式会社 磺酰胺化合物及其结晶

Also Published As

Publication number Publication date
US8232292B2 (en) 2012-07-31
EP2179997A1 (en) 2010-04-28
AU2008272396B2 (en) 2011-09-08
CN101730690A (zh) 2010-06-09
CA2690753C (en) 2013-08-13
CA2690753A1 (en) 2009-01-08
WO2009004792A1 (ja) 2009-01-08
EP2179997B1 (en) 2012-11-14
HK1141028A1 (en) 2010-10-29
CN101730690B (zh) 2013-01-16
KR101246392B1 (ko) 2013-03-21
JPWO2009004792A1 (ja) 2010-08-26
US8664243B2 (en) 2014-03-04
JP5476436B2 (ja) 2014-04-23
AU2008272396A1 (en) 2009-01-08
JP5234825B2 (ja) 2013-07-10
EP2179997A4 (en) 2012-02-22
US20090156823A1 (en) 2009-06-18
US20120270898A1 (en) 2012-10-25
JP2012236858A (ja) 2012-12-06
ES2396795T3 (es) 2013-02-27
KR20100017698A (ko) 2010-02-16

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