ES2391410T3 - Procedimientos para la preparación de diferentes formas de (s)-(+)-clopidogrel besilato - Google Patents

Procedimientos para la preparación de diferentes formas de (s)-(+)-clopidogrel besilato Download PDF

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Publication number
ES2391410T3
ES2391410T3 ES06842727T ES06842727T ES2391410T3 ES 2391410 T3 ES2391410 T3 ES 2391410T3 ES 06842727 T ES06842727 T ES 06842727T ES 06842727 T ES06842727 T ES 06842727T ES 2391410 T3 ES2391410 T3 ES 2391410T3
Authority
ES
Spain
Prior art keywords
clopidogrel
heptanol
besylate
preparation
hexanol
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
ES06842727T
Other languages
English (en)
Spanish (es)
Inventor
Braj Bhushan Lohray
Vidya Bhushan Lohray
Bipin Pandey
Mayank Ghanshyambhai Dave
Parind Narendra Dholakia
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Zydus Lifesciences Ltd
Original Assignee
Cadila Healthcare Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Cadila Healthcare Ltd filed Critical Cadila Healthcare Ltd
Application granted granted Critical
Publication of ES2391410T3 publication Critical patent/ES2391410T3/es
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
    • C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D495/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Cardiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Vascular Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Urology & Nephrology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Medicinal Preparation (AREA)
ES06842727T 2005-09-05 2006-08-28 Procedimientos para la preparación de diferentes formas de (s)-(+)-clopidogrel besilato Active ES2391410T3 (es)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
INMU10722005 2005-09-05
IN1072MU2005 2005-09-05
PCT/IN2006/000322 WO2007052300A2 (fr) 2005-09-05 2006-08-28 Procedes de preparation de differentes formes de (s)-(+)-clopidogrel besylate

Publications (1)

Publication Number Publication Date
ES2391410T3 true ES2391410T3 (es) 2012-11-26

Family

ID=37898811

Family Applications (1)

Application Number Title Priority Date Filing Date
ES06842727T Active ES2391410T3 (es) 2005-09-05 2006-08-28 Procedimientos para la preparación de diferentes formas de (s)-(+)-clopidogrel besilato

Country Status (4)

Country Link
US (2) US7994322B2 (fr)
EP (1) EP1934229B1 (fr)
ES (1) ES2391410T3 (fr)
WO (1) WO2007052300A2 (fr)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2012123958A1 (fr) 2011-02-14 2012-09-20 Cadila Healthcare Limited Sels très purs de clopidogrel exempts d'impuretés génotoxiques
CN104193762B (zh) * 2014-08-04 2017-02-15 浙江车头制药股份有限公司 一种制备苯磺酸氯吡格雷晶型ⅲ的方法

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2530247B1 (fr) 1982-07-13 1986-05-16 Sanofi Sa Nouveaux derives de la thieno (3, 2-c) pyridine, leur procede de preparation et leur application therapeutique
FR2623810B2 (fr) 1987-02-17 1992-01-24 Sanofi Sa Sels de l'alpha-(tetrahydro-4,5,6,7 thieno(3,2-c) pyridyl-5) (chloro-2 phenyl) -acetate de methyle dextrogyre et compositions pharmaceutiques en contenant
FR2779726B1 (fr) 1998-06-15 2001-05-18 Sanofi Sa Forme polymorphe de l'hydrogenosulfate de clopidogrel
DE19857137A1 (de) 1998-12-11 2000-06-15 Bayer Ag Integriertes Verfahren zur Herstellung von Epoxiden aus Olefinen
IN191030B (fr) 2001-01-24 2003-09-13 Cadila Healthcare Ltd
DE10305984A1 (de) * 2003-02-13 2004-09-02 Helm Ag Salze organischer Säuren mit Clopidogrel und deren Verwendung zur Herstellung phamazeutischer Formulierungen
AU2003238664A1 (en) 2003-03-12 2004-09-30 Cadila Healthcare Limited Polymorphs and amorphous form of (s) - (+) -clopidogrel bisulfate
DK1618111T3 (en) * 2003-04-25 2015-02-16 Cadila Healthcare Ltd Salts of clopidogrel and the process for preparing
CN1922188A (zh) 2004-02-24 2007-02-28 齐格弗里德通用国际股份公司 氯吡格雷之药学可接受的盐

Also Published As

Publication number Publication date
US20100081824A1 (en) 2010-04-01
US20090221827A1 (en) 2009-09-03
WO2007052300A3 (fr) 2007-07-12
EP1934229B1 (fr) 2012-09-26
WO2007052300A2 (fr) 2007-05-10
EP1934229A2 (fr) 2008-06-25
US7994322B2 (en) 2011-08-09

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