ES2354115T3 - Procedimiento para la síntesis de 5-(metil-1h-imidazol-1-il)-3-(trifluorometil)-bencenamina. - Google Patents

Procedimiento para la síntesis de 5-(metil-1h-imidazol-1-il)-3-(trifluorometil)-bencenamina. Download PDF

Info

Publication number
ES2354115T3
ES2354115T3 ES06772366T ES06772366T ES2354115T3 ES 2354115 T3 ES2354115 T3 ES 2354115T3 ES 06772366 T ES06772366 T ES 06772366T ES 06772366 T ES06772366 T ES 06772366T ES 2354115 T3 ES2354115 T3 ES 2354115T3
Authority
ES
Spain
Prior art keywords
methyl
imidazole
compound
trifluoromethyl
procedure
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES06772366T
Other languages
English (en)
Spanish (es)
Inventor
Murat Acemoglu
Erich Widmer
Song Xue
Berthold Schenkel
Pedro Garcia Fuentes
Jose Martin Medina
Francisco Vicente Bauos
Wen-Chung Shieh
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Novartis Pharma GmbH
Novartis AG
Original Assignee
Novartis Pharma GmbH
Novartis AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novartis Pharma GmbH, Novartis AG filed Critical Novartis Pharma GmbH
Application granted granted Critical
Publication of ES2354115T3 publication Critical patent/ES2354115T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/56—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, attached to ring carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/64—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with substituted hydrocarbon radicals attached to ring carbon atoms, e.g. histidine
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
ES06772366T 2005-06-09 2006-06-07 Procedimiento para la síntesis de 5-(metil-1h-imidazol-1-il)-3-(trifluorometil)-bencenamina. Expired - Lifetime ES2354115T3 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US68892005P 2005-06-09 2005-06-09
US688920P 2005-06-09

Publications (1)

Publication Number Publication Date
ES2354115T3 true ES2354115T3 (es) 2011-03-10

Family

ID=37085334

Family Applications (1)

Application Number Title Priority Date Filing Date
ES06772366T Expired - Lifetime ES2354115T3 (es) 2005-06-09 2006-06-07 Procedimiento para la síntesis de 5-(metil-1h-imidazol-1-il)-3-(trifluorometil)-bencenamina.

Country Status (20)

Country Link
US (1) US7709657B2 (enExample)
EP (1) EP1896425B1 (enExample)
JP (1) JP5139273B2 (enExample)
KR (1) KR101319071B1 (enExample)
CN (1) CN101193866B (enExample)
AR (1) AR057351A1 (enExample)
AT (1) ATE483690T1 (enExample)
AU (1) AU2006258116B2 (enExample)
BR (1) BRPI0611924A2 (enExample)
CA (1) CA2610402C (enExample)
DE (1) DE602006017369D1 (enExample)
ES (1) ES2354115T3 (enExample)
GT (1) GT200600207A (enExample)
MX (1) MX2007015420A (enExample)
PE (1) PE20070084A1 (enExample)
PL (1) PL1896425T3 (enExample)
PT (1) PT1896425E (enExample)
RU (1) RU2404167C2 (enExample)
TW (1) TW200710084A (enExample)
WO (1) WO2006135619A1 (enExample)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MY146795A (en) * 2005-06-09 2012-09-28 Novartis Ag Process for the synthesis of organic compounds
GB0618832D0 (en) * 2006-09-25 2006-11-01 Phoenix Chemicals Ltd Chemical process
US20110053968A1 (en) 2009-06-09 2011-03-03 Auspex Pharmaceuticals, Inc. Aminopyrimidine inhibitors of tyrosine kinase
CN106536303B (zh) 2014-05-16 2019-08-13 罗伯特·博世有限公司 Abs液压单元
KR102335216B1 (ko) 2017-04-26 2021-12-03 삼성전자 주식회사 발광소자 패키지
CN107235910B (zh) * 2017-07-31 2020-04-24 安礼特（上海）医药科技有限公司 一种尼洛胺的合成方法
CN108530364B (zh) 2018-04-10 2020-01-21 江苏创诺制药有限公司 一种3-(4-甲基-1h-咪唑-1-基)-5-三氟甲基苯胺单盐酸盐的晶型及其应用
TWI787523B (zh) 2018-06-15 2022-12-21 漢達生技醫藥股份有限公司 達沙替尼十二烷基硫酸鹽之結晶
EP3904342A1 (en) 2020-04-28 2021-11-03 Grindeks, A Joint Stock Company Process for the preparation of 3-(trifluoromethyl)-5-(4-methyl-1h-imidazole-1-yl)-benzeneamine hydrochloride

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8413685D0 (en) * 1984-05-29 1984-07-04 Pfizer Ltd Quinolone inotropic agents
US5516775A (en) * 1992-08-31 1996-05-14 Ciba-Geigy Corporation Further use of pyrimidine derivatives
DE69429078T2 (de) * 1993-10-01 2002-07-11 Novartis Ag, Basel Pharmacologisch wirksame pyridinderivate und verfahren zu deren herstellung
US6323366B1 (en) * 1997-07-29 2001-11-27 Massachusetts Institute Of Technology Arylamine synthesis
US6395916B1 (en) * 1998-07-10 2002-05-28 Massachusetts Institute Of Technology Ligands for metals and improved metal-catalyzed processes based thereon
HN2001000008A (es) * 2000-01-21 2003-12-11 Inc Agouron Pharmaceuticals Compuesto de amida y composiciones farmaceuticas para inhibir proteinquinasas, y su modo de empleo
PE20040522A1 (es) * 2002-05-29 2004-09-28 Novartis Ag Derivados de diarilurea dependientes de la cinasa de proteina
US7202367B2 (en) * 2002-05-31 2007-04-10 Rhodia Chimie Process for arylating or vinylating or alkynating a nucleophilic compound
GB0215676D0 (en) * 2002-07-05 2002-08-14 Novartis Ag Organic compounds

Also Published As

Publication number Publication date
PL1896425T3 (pl) 2011-04-29
GT200600207A (es) 2007-01-15
US20080200691A1 (en) 2008-08-21
CA2610402A1 (en) 2006-12-21
CN101193866B (zh) 2011-01-19
JP5139273B2 (ja) 2013-02-06
EP1896425B1 (en) 2010-10-06
RU2007147927A (ru) 2009-07-20
CN101193866A (zh) 2008-06-04
AU2006258116B2 (en) 2010-11-25
US7709657B2 (en) 2010-05-04
WO2006135619A1 (en) 2006-12-21
MX2007015420A (es) 2008-02-21
BRPI0611924A2 (pt) 2010-10-05
PE20070084A1 (es) 2007-03-09
AU2006258116A1 (en) 2006-12-21
RU2404167C2 (ru) 2010-11-20
AR057351A1 (es) 2007-11-28
DE602006017369D1 (de) 2010-11-18
EP1896425A1 (en) 2008-03-12
KR101319071B1 (ko) 2013-10-17
PT1896425E (pt) 2010-11-30
CA2610402C (en) 2014-09-16
JP2008545782A (ja) 2008-12-18
KR20080016618A (ko) 2008-02-21
ATE483690T1 (de) 2010-10-15
TW200710084A (en) 2007-03-16

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