ES2333973T3 - Derivados de pirimidina utiles como ligandos del receptor de vaniloide y sus utilizaciones en el tratamiento del dolor. - Google Patents
Derivados de pirimidina utiles como ligandos del receptor de vaniloide y sus utilizaciones en el tratamiento del dolor. Download PDFInfo
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- ES2333973T3 ES2333973T3 ES05722962T ES05722962T ES2333973T3 ES 2333973 T3 ES2333973 T3 ES 2333973T3 ES 05722962 T ES05722962 T ES 05722962T ES 05722962 T ES05722962 T ES 05722962T ES 2333973 T3 ES2333973 T3 ES 2333973T3
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- pain
- inflammatory
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- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
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| US54389604P | 2004-02-11 | 2004-02-11 | |
| US543896P | 2004-02-11 |
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| WO2006006740A1 (ja) * | 2004-07-14 | 2006-01-19 | Japan Tobacco Inc. | ３−アミノベンズアミド化合物及びバニロイド受容体１型(ｖｒ１)活性阻害剤 |
| MX2007000480A (es) | 2004-07-15 | 2007-03-29 | Japan Tobacco Inc | Compuesto de benzamida fusionado e inhibidor de actividad de receptor de vainilloide 1. |
| US7301022B2 (en) | 2005-02-15 | 2007-11-27 | Amgen Inc. | Vanilloid receptor ligands and their use in treatments |
| EP1967519B1 (en) * | 2005-12-28 | 2012-09-05 | Japan Tobacco Inc. | 3,4-dihydrobenzoxazine compound and inhibitor of vanilloid receptor type 1 (vr1) activity |
| US7906508B2 (en) * | 2005-12-28 | 2011-03-15 | Japan Tobacco Inc. | 3,4-dihydrobenzoxazine compounds and inhibitors of vanilloid receptor subtype 1 (VRI) activity |
| BRPI0818003A2 (pt) * | 2007-10-18 | 2019-09-24 | Novartis Ag | inibidores de csf-1r, composições e métodos de uso |
| US7905954B2 (en) * | 2008-03-07 | 2011-03-15 | Xerox Corporation | Nanosized particles of benzimidazolone pigments |
| US8025723B2 (en) | 2008-03-07 | 2011-09-27 | Xerox Corporation | Nonpolar liquid and solid phase change ink compositions comprising nanosized particles of benzimidazolone pigments |
| US7985290B2 (en) | 2008-03-07 | 2011-07-26 | Xerox Corporation | Nonpolar liquid and solid phase change ink compositions comprising nanosized particles of benzimidazolone pigments |
| US7938903B2 (en) * | 2008-03-07 | 2011-05-10 | Xerox Corporation | Nanosized particles of benzimidazolone pigments |
| US7857901B2 (en) * | 2008-03-07 | 2010-12-28 | Xerox Corporation | Nonpolar liquid and solid phase change ink compositions comprising nanosized particles of benzimidazolone pigments |
| US8012254B2 (en) | 2008-03-07 | 2011-09-06 | Xerox Corporation | Nanosized particles of benzimidazolone pigments |
| US7883574B2 (en) | 2008-03-07 | 2011-02-08 | Xerox Corporation | Methods of making nanosized particles of benzimidazolone pigments |
| HRP20131069T1 (hr) | 2008-06-16 | 2013-12-20 | Merck Patent Gmbh | Derivati kinoksalindiona |
| EP2416766B1 (en) | 2009-04-09 | 2014-04-09 | Symrise AG | Compositions comprising trans-tert-butyl cyclohexanol as skin irritation-reducing agent |
| US8362270B2 (en) | 2010-05-11 | 2013-01-29 | Xerox Corporation | Self-assembled nanostructures |
| US8703988B2 (en) | 2010-06-22 | 2014-04-22 | Xerox Corporation | Self-assembled nanostructures |
| EP2322512B1 (en) | 2009-10-19 | 2015-10-21 | Xerox Corporation | Alkylated benzimidazolone compounds and self-assembled nanostructures generated therefrom |
| KR102678074B1 (ko) * | 2012-05-17 | 2024-06-26 | 제넨테크, 인크. | 무정형 형태의 akt 저해성 피리미디닐 - 사이클로펜탄 화합물, 조성물 및 이들의 방법 |
| CN103923033B (zh) * | 2013-01-14 | 2015-11-18 | 天津药物研究院 | 具有抗胃溃疡作用的哌嗪类衍生物 |
| US10537552B2 (en) | 2015-05-05 | 2020-01-21 | Carafe Drug Innovation, Llc | Substituted 5-hydroxyoxindoles and their use as analgesics and fever reducers |
| CN111393380A (zh) * | 2018-07-09 | 2020-07-10 | 湖南博隽生物医药有限公司 | 一种用于治疗慢性炎性痛的辣椒素受体拮抗剂 |
| PY2311120A (es) * | 2022-03-01 | 2023-09-14 | Syngenta Crop Protection Ag | Compuestos herbicidas |
| CN120398870A (zh) * | 2024-01-31 | 2025-08-01 | 深圳晶蛋生物医药科技有限公司 | 一种苯并吗啉类化合物及其应用 |
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2005
- 2005-02-08 MY MYPI20050501A patent/MY139645A/en unknown
- 2005-02-11 DE DE602005017468T patent/DE602005017468D1/de not_active Expired - Fee Related
- 2005-02-11 JP JP2006553265A patent/JP2007522235A/ja not_active Withdrawn
- 2005-02-11 CA CA002555685A patent/CA2555685A1/en not_active Abandoned
- 2005-02-11 AR ARP050100490A patent/AR049771A1/es not_active Application Discontinuation
- 2005-02-11 CN CNA200580008675XA patent/CN1953976A/zh active Pending
- 2005-02-11 WO PCT/US2005/004378 patent/WO2005077944A1/en not_active Ceased
- 2005-02-11 EP EP05722962A patent/EP1720868B1/en not_active Expired - Lifetime
- 2005-02-11 ES ES05722962T patent/ES2333973T3/es not_active Expired - Lifetime
- 2005-02-11 AT AT05722962T patent/ATE447570T1/de not_active IP Right Cessation
- 2005-02-11 AU AU2005212517A patent/AU2005212517B2/en not_active Ceased
- 2005-02-11 BR BRPI0507927-6A patent/BRPI0507927A/pt not_active IP Right Cessation
- 2005-02-11 KR KR1020067018172A patent/KR100813093B1/ko not_active Expired - Fee Related
- 2005-02-11 EA EA200601426A patent/EA010265B1/ru not_active IP Right Cessation
- 2005-02-11 US US11/056,568 patent/US7511044B2/en not_active Expired - Fee Related
- 2005-02-14 TW TW094104222A patent/TWI295670B/zh active
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2006
- 2006-08-08 IL IL177369A patent/IL177369A0/en unknown
- 2006-09-08 ZA ZA200607518A patent/ZA200607518B/en unknown
- 2006-09-08 NO NO20064055A patent/NO20064055L/no not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
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| AU2005212517B2 (en) | 2009-05-21 |
| TWI295670B (en) | 2008-04-11 |
| AU2005212517A1 (en) | 2005-08-25 |
| US7511044B2 (en) | 2009-03-31 |
| CA2555685A1 (en) | 2005-08-25 |
| ATE447570T1 (de) | 2009-11-15 |
| IL177369A0 (en) | 2006-12-10 |
| EA010265B1 (ru) | 2008-06-30 |
| US20050176726A1 (en) | 2005-08-11 |
| KR20070033325A (ko) | 2007-03-26 |
| EP1720868B1 (en) | 2009-11-04 |
| TW200534858A (en) | 2005-11-01 |
| AR049771A1 (es) | 2006-09-06 |
| CN1953976A (zh) | 2007-04-25 |
| EP1720868A1 (en) | 2006-11-15 |
| EA200601426A1 (ru) | 2007-02-27 |
| MY139645A (en) | 2009-10-30 |
| DE602005017468D1 (de) | 2009-12-17 |
| WO2005077944A1 (en) | 2005-08-25 |
| JP2007522235A (ja) | 2007-08-09 |
| ZA200607518B (en) | 2008-07-30 |
| KR100813093B1 (ko) | 2008-03-17 |
| NO20064055L (no) | 2006-10-24 |
| BRPI0507927A (pt) | 2007-07-17 |
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