ES2319107T3 - Derivados de 5-halo-triptamina usados como ligandos de los receptores de serotonina 5-ht6 y/o 5-ht7. - Google Patents
Derivados de 5-halo-triptamina usados como ligandos de los receptores de serotonina 5-ht6 y/o 5-ht7. Download PDFInfo
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- ES2319107T3 ES2319107T3 ES02745793T ES02745793T ES2319107T3 ES 2319107 T3 ES2319107 T3 ES 2319107T3 ES 02745793 T ES02745793 T ES 02745793T ES 02745793 T ES02745793 T ES 02745793T ES 2319107 T3 ES2319107 T3 ES 2319107T3
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Classifications
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- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/04—Indoles; Hydrogenated indoles
- C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
- C07D209/14—Radicals substituted by nitrogen atoms, not forming part of a nitro radical
- C07D209/16—Tryptamines
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- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
- A61K31/403—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with carbocyclic rings, e.g. carbazole
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- A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
- A61K31/403—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with carbocyclic rings, e.g. carbazole
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- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
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Landscapes
- Health & Medical Sciences (AREA)
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- Engineering & Computer Science (AREA)
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- Hospice & Palliative Care (AREA)
- Anesthesiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Indole Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| ITRM01A0356 | 2001-06-21 | ||
| IT2001RM000356A ITRM20010356A1 (it) | 2001-06-21 | 2001-06-21 | "5-alogeno derivati della triptamina utili come ligandi del recettore5-ht6 e/o 5-ht7 della serotonina. |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES2319107T3 true ES2319107T3 (es) | 2009-05-04 |
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES02745793T Expired - Lifetime ES2319107T3 (es) | 2001-06-21 | 2002-06-17 | Derivados de 5-halo-triptamina usados como ligandos de los receptores de serotonina 5-ht6 y/o 5-ht7. |
Country Status (21)
| Country | Link |
|---|---|
| US (1) | US7098233B2 (OSRAM) |
| EP (1) | EP1404317B1 (OSRAM) |
| JP (2) | JP4683839B2 (OSRAM) |
| KR (1) | KR100885308B1 (OSRAM) |
| CN (1) | CN100482223C (OSRAM) |
| AT (1) | ATE416767T1 (OSRAM) |
| AU (1) | AU2002317482B2 (OSRAM) |
| BR (1) | BR0210538A (OSRAM) |
| CA (1) | CA2455296C (OSRAM) |
| CY (1) | CY1108879T1 (OSRAM) |
| CZ (1) | CZ20033314A3 (OSRAM) |
| DE (1) | DE60230270D1 (OSRAM) |
| DK (1) | DK1404317T3 (OSRAM) |
| ES (1) | ES2319107T3 (OSRAM) |
| HU (1) | HUP0400250A3 (OSRAM) |
| IT (1) | ITRM20010356A1 (OSRAM) |
| MX (1) | MXPA03011510A (OSRAM) |
| PL (1) | PL367618A1 (OSRAM) |
| PT (1) | PT1404317E (OSRAM) |
| SK (1) | SK287828B6 (OSRAM) |
| WO (1) | WO2003000252A1 (OSRAM) |
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| Publication number | Priority date | Publication date | Assignee | Title |
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| AR039127A1 (es) | 2002-03-27 | 2005-02-09 | Glaxo Group Ltd | Compuesto de quinolina, procedimiento para su preparacion, composicion farmaceutica que lo comprende y uso del mismo para la fabricacion de un medicamento |
| RS20060035A (sr) | 2003-07-22 | 2008-08-07 | Arena Pharmaceuticals Inc., | Derivati diaril i arilheteroaril uree kao modulatori receptora 5-ht2a serotonina korisni u profilaksi i lečenju poremećaja u vezi sa njima |
| US8086315B2 (en) | 2004-02-12 | 2011-12-27 | Asap Medical, Inc. | Cardiac stimulation apparatus and method for the control of hypertension |
| EP1716867A4 (en) | 2004-02-20 | 2009-09-23 | Astellas Pharma Inc | PRENENT AGENTS FOR MIGRAINE |
| WO2006085510A1 (ja) * | 2005-02-08 | 2006-08-17 | Astellas Pharma Inc. | 過敏性腸症候群の治療薬 |
| WO2007018168A1 (ja) * | 2005-08-08 | 2007-02-15 | Astellas Pharma Inc. | アシルグアニジン誘導体またはその塩 |
| WO2007046112A1 (en) * | 2005-10-19 | 2007-04-26 | Suven Life Sciences Inc. | Arylthioether tryptamine derivatives as functional 5-ht6 ligands |
| JP5157893B2 (ja) * | 2006-02-20 | 2013-03-06 | アステラス製薬株式会社 | ピロール誘導体またはその塩 |
| WO2008113818A1 (en) * | 2007-03-21 | 2008-09-25 | Glaxo Group Limited | Use of quinoline derivatives in the treatment of pain and irritable bowel syndrome |
| EP2209380A4 (en) * | 2007-10-09 | 2011-09-14 | Mark T Hamann | METHOD OF USE OF COMPOSITIONS WITH ANTIDEPRESSIVE EFFICACY, MOOD EFFICACY AND OTHER NEUROLOGICAL EFFECTIVENESS AND COMPOSITIONS THEREOF |
| EP2508177A1 (en) | 2007-12-12 | 2012-10-10 | Glaxo Group Limited | Combinations comprising 3-phenylsulfonyl-8-piperazinyl-1yl-quinoline |
| WO2009123714A2 (en) | 2008-04-02 | 2009-10-08 | Arena Pharmaceuticals, Inc. | Processes for the preparation of pyrazole derivatives useful as modulators of the 5-ht2a serotonin receptor |
| US9126946B2 (en) | 2008-10-28 | 2015-09-08 | Arena Pharmaceuticals, Inc. | Processes useful for the preparation of 1-[3-(4-bromo-2-methyl-2H-pyrazol-3-yl)-4-methoxy-phenyl]-3-(2,4-difluoro-phenyl)urea and crystalline forms related thereto |
| CN103841966A (zh) * | 2011-08-05 | 2014-06-04 | 苏坎波公司 | 治疗精神分裂症的方法 |
| CN102816103B (zh) * | 2012-08-20 | 2014-05-07 | 冉瑞琼 | 硫化天冬氨酸修饰的退黑素衍生物及其应用 |
| US9008769B2 (en) | 2012-12-21 | 2015-04-14 | Backbeat Medical, Inc. | Methods and systems for lowering blood pressure through reduction of ventricle filling |
| US9370662B2 (en) | 2013-12-19 | 2016-06-21 | Backbeat Medical, Inc. | Methods and systems for controlling blood pressure by controlling atrial pressure |
| CN104529865B (zh) * | 2014-12-12 | 2017-02-01 | 广东东阳光药业有限公司 | 苄胺类衍生物及其在药物上的应用 |
| AU2016276966A1 (en) | 2015-06-12 | 2018-01-18 | Axovant Sciences Gmbh | Diaryl and arylheteroaryl urea derivatives useful for the prophylaxis and treatment of REM sleep behavior disorder |
| EP3322415A4 (en) | 2015-07-15 | 2019-03-13 | Axovant Sciences GmbH | DIARYL AND ARYLHETEROARYL UREA DERIVATIVES AS MODULATORS OF THE 5-HT2A SEROTONIN RECEPTOR FOR PROPHYLAXIS AND TREATMENT OF HALLUCINATIONS RELATED TO A NEUROGENERATIVE DISEASE |
| US10342982B2 (en) | 2015-09-11 | 2019-07-09 | Backbeat Medical, Inc. | Methods and systems for treating cardiac malfunction |
| US10485658B2 (en) | 2016-04-22 | 2019-11-26 | Backbeat Medical, Inc. | Methods and systems for controlling blood pressure |
| CN108926565A (zh) * | 2017-05-26 | 2018-12-04 | 中国科学院上海生命科学研究院 | 五羟色胺受体亚型6小分子激活剂及拮抗剂在防治阿尔茨海默症中的应用 |
| CA3148256A1 (en) * | 2018-06-21 | 2019-12-26 | Robert John Petcavich | Method of inducing dendritic and synaptic genesis in neurodegenerative chronic diseases |
| GB201907871D0 (en) * | 2019-06-03 | 2019-07-17 | Small Pharma Ltd | Therapeutic compositions |
| JP7242969B2 (ja) * | 2020-02-18 | 2023-03-20 | ギルガメッシュ・ファーマシューティカルズ・インコーポレイテッド | 気分障害の処置での使用に特異的なトリプタミン |
| IL297861A (en) | 2020-05-08 | 2023-01-01 | Psilera Inc | Novel compositions of matter and pharmaceutical compositions |
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| US20240343692A1 (en) * | 2021-08-09 | 2024-10-17 | University Of Pittsburgh - Of The Commonwealth System Of Higher Education | Selective psychedelic compounds |
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| US2825734A (en) * | 1955-04-11 | 1958-03-04 | Upjohn Co | Reduction of carbonylic radicals in indolyl-3 compounds |
| GB966562A (en) * | 1961-04-06 | 1964-08-12 | Parke Davis & Co | Amine compounds and means of producing the same |
| FR2315277A1 (fr) * | 1975-06-25 | 1977-01-21 | Anvar | Nouveaux derives pentacycliques, leur preparation et les compositions qui les contiennent |
| US4428877A (en) * | 1978-07-12 | 1984-01-31 | Richter Gedeon Vegyeszeti Gyar Rt. | Cis-10-bromo-E-homoeburnanes |
| GB8531612D0 (en) * | 1985-12-23 | 1986-02-05 | Beecham Wuelfing Gmbh & Co Kg | Compounds |
| US5300645A (en) * | 1993-04-14 | 1994-04-05 | Eli Lilly And Company | Tetrahydro-pyrido-indole |
| FR2712591B1 (fr) * | 1993-11-19 | 1996-02-09 | Pf Medicament | Nouvelles arylpipérazines dérivées d'indole, leur préparation et leur utilisation thérapeutique. |
| US5688807A (en) * | 1994-03-11 | 1997-11-18 | Eli Lilly And Company | Method for treating 5HT2B receptor related conditions |
| US5504101A (en) * | 1994-05-06 | 1996-04-02 | Allelix Biopharmaceuticals, Inc. | 5-HT-1D receptor ligands |
| ES2243999T3 (es) | 1996-06-28 | 2005-12-01 | Meiji Seika Kaisha Ltd. | Compuestos de tetrahidrobencindol. |
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| US6251893B1 (en) * | 1998-06-15 | 2001-06-26 | Nps Allelix Corp. | Bicyclic piperidine and piperazine compounds having 5-HT6 receptor affinity |
| US6403808B1 (en) * | 1999-12-10 | 2002-06-11 | Virginia Commonwealth University | Selective 5-HT6 receptor ligands |
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-
2001
- 2001-06-21 IT IT2001RM000356A patent/ITRM20010356A1/it unknown
-
2002
- 2002-06-17 PT PT02745793T patent/PT1404317E/pt unknown
- 2002-06-17 ES ES02745793T patent/ES2319107T3/es not_active Expired - Lifetime
- 2002-06-17 AU AU2002317482A patent/AU2002317482B2/en not_active Ceased
- 2002-06-17 DE DE60230270T patent/DE60230270D1/de not_active Expired - Lifetime
- 2002-06-17 CZ CZ20033314A patent/CZ20033314A3/cs unknown
- 2002-06-17 AT AT02745793T patent/ATE416767T1/de active
- 2002-06-17 WO PCT/IT2002/000398 patent/WO2003000252A1/en not_active Ceased
- 2002-06-17 JP JP2003506898A patent/JP4683839B2/ja not_active Expired - Fee Related
- 2002-06-17 PL PL02367618A patent/PL367618A1/xx not_active IP Right Cessation
- 2002-06-17 US US10/481,433 patent/US7098233B2/en not_active Expired - Fee Related
- 2002-06-17 DK DK02745793T patent/DK1404317T3/da active
- 2002-06-17 BR BR0210538-1A patent/BR0210538A/pt not_active Application Discontinuation
- 2002-06-17 HU HU0400250A patent/HUP0400250A3/hu unknown
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- 2002-06-17 CA CA2455296A patent/CA2455296C/en not_active Expired - Fee Related
- 2002-06-17 EP EP02745793A patent/EP1404317B1/en not_active Expired - Lifetime
- 2002-06-17 SK SK38-2004A patent/SK287828B6/sk not_active IP Right Cessation
- 2002-06-17 CN CNB02814337XA patent/CN100482223C/zh not_active Expired - Fee Related
- 2002-06-17 KR KR1020037016564A patent/KR100885308B1/ko not_active Expired - Fee Related
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2009
- 2009-03-06 CY CY20091100260T patent/CY1108879T1/el unknown
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2010
- 2010-09-13 JP JP2010204733A patent/JP2011016835A/ja active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| HUP0400250A3 (en) | 2008-03-28 |
| SK287828B6 (sk) | 2011-11-04 |
| CA2455296C (en) | 2010-08-17 |
| CN100482223C (zh) | 2009-04-29 |
| ITRM20010356A1 (it) | 2002-12-23 |
| ITRM20010356A0 (it) | 2001-06-21 |
| SK382004A3 (en) | 2004-05-04 |
| MXPA03011510A (es) | 2004-03-18 |
| AU2002317482B2 (en) | 2007-08-16 |
| HK1068792A1 (zh) | 2005-05-06 |
| PT1404317E (pt) | 2009-02-23 |
| EP1404317B1 (en) | 2008-12-10 |
| CY1108879T1 (el) | 2014-07-02 |
| DE60230270D1 (de) | 2009-01-22 |
| CZ20033314A3 (cs) | 2004-08-18 |
| JP2004534816A (ja) | 2004-11-18 |
| ATE416767T1 (de) | 2008-12-15 |
| US20040235899A1 (en) | 2004-11-25 |
| KR100885308B1 (ko) | 2009-02-24 |
| BR0210538A (pt) | 2004-06-22 |
| KR20040032113A (ko) | 2004-04-14 |
| EP1404317A1 (en) | 2004-04-07 |
| WO2003000252A1 (en) | 2003-01-03 |
| DK1404317T3 (da) | 2009-02-23 |
| CA2455296A1 (en) | 2003-01-03 |
| US7098233B2 (en) | 2006-08-29 |
| PL367618A1 (en) | 2005-03-07 |
| CN1535146A (zh) | 2004-10-06 |
| HUP0400250A2 (hu) | 2004-08-30 |
| JP2011016835A (ja) | 2011-01-27 |
| JP4683839B2 (ja) | 2011-05-18 |
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