ES2292636T3 - 1-(2-m-metanosulfanomidofeniletil)-4-(m-trifluorometilfenil)piper. - Google Patents
1-(2-m-metanosulfanomidofeniletil)-4-(m-trifluorometilfenil)piper. Download PDFInfo
- Publication number
- ES2292636T3 ES2292636T3 ES01990644T ES01990644T ES2292636T3 ES 2292636 T3 ES2292636 T3 ES 2292636T3 ES 01990644 T ES01990644 T ES 01990644T ES 01990644 T ES01990644 T ES 01990644T ES 2292636 T3 ES2292636 T3 ES 2292636T3
- Authority
- ES
- Spain
- Prior art keywords
- bladder
- agonist
- compound
- incontinence
- urinary incontinence
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
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- CZDYPVPMEAXLPK-UHFFFAOYSA-N tetramethylsilane Chemical compound C[Si](C)(C)C CZDYPVPMEAXLPK-UHFFFAOYSA-N 0.000 description 1
- 238000004809 thin layer chromatography Methods 0.000 description 1
- 210000001519 tissue Anatomy 0.000 description 1
- OOGJQPCLVADCPB-HXUWFJFHSA-N tolterodine Chemical compound C1([C@@H](CCN(C(C)C)C(C)C)C=2C(=CC=C(C)C=2)O)=CC=CC=C1 OOGJQPCLVADCPB-HXUWFJFHSA-N 0.000 description 1
- 229960004045 tolterodine Drugs 0.000 description 1
- QORWJWZARLRLPR-UHFFFAOYSA-H tricalcium bis(phosphate) Chemical compound [Ca+2].[Ca+2].[Ca+2].[O-]P([O-])([O-])=O.[O-]P([O-])([O-])=O QORWJWZARLRLPR-UHFFFAOYSA-H 0.000 description 1
- 239000003029 tricyclic antidepressant agent Substances 0.000 description 1
- BDIAUFOIMFAIPU-UHFFFAOYSA-N valepotriate Natural products CC(C)CC(=O)OC1C=C(C(=COC2OC(=O)CC(C)C)COC(C)=O)C2C11CO1 BDIAUFOIMFAIPU-UHFFFAOYSA-N 0.000 description 1
- 210000003462 vein Anatomy 0.000 description 1
- 239000000080 wetting agent Substances 0.000 description 1
- 229940071104 xylenesulfonate Drugs 0.000 description 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
- C07D295/12—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly or doubly bound nitrogen atoms
- C07D295/135—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly or doubly bound nitrogen atoms with the ring nitrogen atoms and the substituent nitrogen atoms separated by carbocyclic rings or by carbon chains interrupted by carbocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/10—Drugs for disorders of the urinary system of the bladder
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Urology & Nephrology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US25020300P | 2000-11-29 | 2000-11-29 | |
| US250203P | 2000-11-29 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES2292636T3 true ES2292636T3 (es) | 2008-03-16 |
Family
ID=22946725
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES01990644T Expired - Lifetime ES2292636T3 (es) | 2000-11-29 | 2001-11-16 | 1-(2-m-metanosulfanomidofeniletil)-4-(m-trifluorometilfenil)piper. |
Country Status (9)
| Country | Link |
|---|---|
| US (1) | US6864262B2 (https=) |
| EP (1) | EP1341777B1 (https=) |
| JP (1) | JP2004517081A (https=) |
| AT (1) | ATE374192T1 (https=) |
| AU (1) | AU2002230411A1 (https=) |
| CA (1) | CA2427098A1 (https=) |
| DE (1) | DE60130677T2 (https=) |
| ES (1) | ES2292636T3 (https=) |
| WO (1) | WO2002044159A2 (https=) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| SI2627328T1 (sl) * | 2010-10-15 | 2017-01-31 | Contera Pharma Aps | Kombinacije agonistov receptorjev serotonina za zdravljenje motenj premikanja |
| CN104411301B (zh) | 2012-04-18 | 2018-02-06 | 康特拉医药公司 | 适于改善运动障碍治疗的口服药物配方 |
| AU2017297718B2 (en) | 2016-07-11 | 2023-06-08 | Contera Pharma A/S | Pulsatile drug delivery system for treating morning akinesia |
Family Cites Families (20)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR1300728A (https=) * | 1959-10-20 | 1962-07-02 | ||
| BE755015A (fr) * | 1969-08-20 | 1971-02-01 | Byk Gulden Lomberg Chem Fab | Piperazinyl-alcoylamino-uraciles substitues par un groupe aryle, leurs ethers et thioethers, ainsi que leur procede de preparation |
| BE759371A (fr) * | 1969-11-24 | 1971-05-24 | Bristol Myers Co | Azaspirodecanediones heterocycliques et procedes pour leur preparation |
| FR2362628A1 (fr) * | 1976-08-26 | 1978-03-24 | Roussel Uclaf | Nouveaux derives du piperidyl-indole et leurs sels, procede de preparation et application a titre de medicaments |
| US4423049A (en) * | 1981-12-28 | 1983-12-27 | Mead Johnson & Company | 2-[4-[(4,4-Dialkyl-2,6-piperidinedion-1-yl)butyl]-1-piperazinyl]pyrimidines |
| DE3321969A1 (de) * | 1983-06-18 | 1984-12-20 | Troponwerke GmbH & Co KG, 5000 Köln | 2-pyrimidinyl-1-piperazin-derivate, verfahren zu ihrer herstellung und diese enthaltende arzneimittel |
| AU577802B2 (en) * | 1983-10-17 | 1988-10-06 | Duphar International Research B.V. | Blood-pressure lowering piperazine derivatives |
| AU611469B2 (en) * | 1987-08-13 | 1991-06-13 | Glaxo Group Limited | Indole derivatives |
| ATE139230T1 (de) | 1988-12-15 | 1996-06-15 | Abbott Lab | 5-ht-selektive mittel |
| PT97888B (pt) * | 1990-06-07 | 1998-12-31 | Zeneca Ltd | Processo para a preparacao de compostos heterociclicos derivados de indol e de composicoes farmaceuticas que os contem |
| US5545644A (en) * | 1990-10-15 | 1996-08-13 | Pfizer Inc. | Indole derivatives |
| CZ283018B6 (cs) * | 1991-02-01 | 1997-12-17 | Merck Sharp And Dohme Limited | Deriváty imidazolu, triazolu a tetrazolu a farmaceutické přípravky na jejich bázi |
| PT533268E (pt) * | 1991-09-18 | 2002-02-28 | Glaxo Group Ltd | Derivados de benzanilida como antagonistas de 5-ht1d |
| CA2084531A1 (en) * | 1991-12-19 | 1993-06-20 | David W. Smith | Antimigraine 4-pyrimidinyl and pyridinyl derivatives of indol-3yl-alkyl piperazines |
| SI9300097B (en) * | 1992-02-27 | 2001-12-31 | Janssen Pharmaceutica Nv | (benzodioxan, benzofuran or benzopyran) alkylamino) alkyl substituted guanidines |
| US5521188A (en) * | 1993-09-16 | 1996-05-28 | Bristol-Myers Squibb Company | Antimigraine cyclobutenedione derivatives of indolylalkyl-pyridinyl and pyrimidinylpiperazines |
| US5801170A (en) * | 1993-12-07 | 1998-09-01 | Smithkline Beecham Plc | Heterocyclic biphenylylamides useful as 5HT1D antagonists |
| SE9504661D0 (sv) | 1995-12-22 | 1995-12-22 | Astra Pharma Inc | New compounds |
| AU736510B2 (en) * | 1997-06-27 | 2001-07-26 | Nippon Kayaku Kabushiki Kaisha | Remedies/preventives for frequent urination/urinary incontinence and tropone derivatives |
| JP3441636B2 (ja) | 1997-11-21 | 2003-09-02 | 株式会社エヌ・ティ・ティ・ドコモ | チャネル推定値を求める装置および方法、受信装置ならびに伝送システム |
-
2001
- 2001-11-16 AT AT01990644T patent/ATE374192T1/de not_active IP Right Cessation
- 2001-11-16 JP JP2002546529A patent/JP2004517081A/ja active Pending
- 2001-11-16 US US10/432,413 patent/US6864262B2/en not_active Expired - Fee Related
- 2001-11-16 EP EP01990644A patent/EP1341777B1/en not_active Expired - Lifetime
- 2001-11-16 ES ES01990644T patent/ES2292636T3/es not_active Expired - Lifetime
- 2001-11-16 DE DE60130677T patent/DE60130677T2/de not_active Expired - Fee Related
- 2001-11-16 CA CA002427098A patent/CA2427098A1/en not_active Abandoned
- 2001-11-16 WO PCT/US2001/042949 patent/WO2002044159A2/en not_active Ceased
- 2001-11-16 AU AU2002230411A patent/AU2002230411A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| WO2002044159A8 (en) | 2003-11-20 |
| AU2002230411A1 (en) | 2002-06-11 |
| WO2002044159A3 (en) | 2002-08-22 |
| CA2427098A1 (en) | 2002-06-06 |
| JP2004517081A (ja) | 2004-06-10 |
| US20040067962A1 (en) | 2004-04-08 |
| DE60130677T2 (de) | 2008-07-17 |
| US6864262B2 (en) | 2005-03-08 |
| ATE374192T1 (de) | 2007-10-15 |
| DE60130677D1 (de) | 2007-11-08 |
| EP1341777A2 (en) | 2003-09-10 |
| EP1341777B1 (en) | 2007-09-26 |
| WO2002044159A2 (en) | 2002-06-06 |
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