AU2002230411A1 - 1-(2-m-methanesulfonamidophenylethyl)-4-(m-trifluoromethylphenyl)piperazine and pharmaceutically acceptable salts and solvates thereof and their use in the treatment of incontinence - Google Patents

1-(2-m-methanesulfonamidophenylethyl)-4-(m-trifluoromethylphenyl)piperazine and pharmaceutically acceptable salts and solvates thereof and their use in the treatment of incontinence

Info

Publication number
AU2002230411A1
AU2002230411A1 AU2002230411A AU3041102A AU2002230411A1 AU 2002230411 A1 AU2002230411 A1 AU 2002230411A1 AU 2002230411 A AU2002230411 A AU 2002230411A AU 3041102 A AU3041102 A AU 3041102A AU 2002230411 A1 AU2002230411 A1 AU 2002230411A1
Authority
AU
Australia
Prior art keywords
solvates
pharmaceutically acceptable
acceptable salts
incontinence
methanesulfonamidophenylethyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU2002230411A
Other languages
English (en)
Inventor
John Mehnert Schaus
Dennis Charles Thompson
Karl Bruce Thor
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Eli Lilly and Co
Original Assignee
Eli Lilly and Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Eli Lilly and Co filed Critical Eli Lilly and Co
Publication of AU2002230411A1 publication Critical patent/AU2002230411A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/12—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly or doubly bound nitrogen atoms
    • C07D295/135—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly or doubly bound nitrogen atoms with the ring nitrogen atoms and the substituent nitrogen atoms separated by carbocyclic rings or by carbon chains interrupted by carbocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/10—Drugs for disorders of the urinary system of the bladder

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Urology & Nephrology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
AU2002230411A 2000-11-29 2001-11-16 1-(2-m-methanesulfonamidophenylethyl)-4-(m-trifluoromethylphenyl)piperazine and pharmaceutically acceptable salts and solvates thereof and their use in the treatment of incontinence Abandoned AU2002230411A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US25020300P 2000-11-29 2000-11-29
US60/250,203 2000-11-29
PCT/US2001/042949 WO2002044159A2 (en) 2000-11-29 2001-11-16 1-(2-m-methanesulfonamidophenylethyl)-4-(m-trifluoromethylphenyl)piperazine and pharmaceutically acceptable salts and solvates thereof and their use in the treatment of incontinence

Publications (1)

Publication Number Publication Date
AU2002230411A1 true AU2002230411A1 (en) 2002-06-11

Family

ID=22946725

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2002230411A Abandoned AU2002230411A1 (en) 2000-11-29 2001-11-16 1-(2-m-methanesulfonamidophenylethyl)-4-(m-trifluoromethylphenyl)piperazine and pharmaceutically acceptable salts and solvates thereof and their use in the treatment of incontinence

Country Status (9)

Country Link
US (1) US6864262B2 (https=)
EP (1) EP1341777B1 (https=)
JP (1) JP2004517081A (https=)
AT (1) ATE374192T1 (https=)
AU (1) AU2002230411A1 (https=)
CA (1) CA2427098A1 (https=)
DE (1) DE60130677T2 (https=)
ES (1) ES2292636T3 (https=)
WO (1) WO2002044159A2 (https=)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SI2627328T1 (sl) * 2010-10-15 2017-01-31 Contera Pharma Aps Kombinacije agonistov receptorjev serotonina za zdravljenje motenj premikanja
CN104411301B (zh) 2012-04-18 2018-02-06 康特拉医药公司 适于改善运动障碍治疗的口服药物配方
AU2017297718B2 (en) 2016-07-11 2023-06-08 Contera Pharma A/S Pulsatile drug delivery system for treating morning akinesia

Family Cites Families (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR1300728A (https=) * 1959-10-20 1962-07-02
BE755015A (fr) * 1969-08-20 1971-02-01 Byk Gulden Lomberg Chem Fab Piperazinyl-alcoylamino-uraciles substitues par un groupe aryle, leurs ethers et thioethers, ainsi que leur procede de preparation
BE759371A (fr) * 1969-11-24 1971-05-24 Bristol Myers Co Azaspirodecanediones heterocycliques et procedes pour leur preparation
FR2362628A1 (fr) * 1976-08-26 1978-03-24 Roussel Uclaf Nouveaux derives du piperidyl-indole et leurs sels, procede de preparation et application a titre de medicaments
US4423049A (en) * 1981-12-28 1983-12-27 Mead Johnson & Company 2-[4-[(4,4-Dialkyl-2,6-piperidinedion-1-yl)butyl]-1-piperazinyl]pyrimidines
DE3321969A1 (de) * 1983-06-18 1984-12-20 Troponwerke GmbH & Co KG, 5000 Köln 2-pyrimidinyl-1-piperazin-derivate, verfahren zu ihrer herstellung und diese enthaltende arzneimittel
AU577802B2 (en) * 1983-10-17 1988-10-06 Duphar International Research B.V. Blood-pressure lowering piperazine derivatives
AU611469B2 (en) * 1987-08-13 1991-06-13 Glaxo Group Limited Indole derivatives
ATE139230T1 (de) 1988-12-15 1996-06-15 Abbott Lab 5-ht-selektive mittel
PT97888B (pt) * 1990-06-07 1998-12-31 Zeneca Ltd Processo para a preparacao de compostos heterociclicos derivados de indol e de composicoes farmaceuticas que os contem
US5545644A (en) * 1990-10-15 1996-08-13 Pfizer Inc. Indole derivatives
CZ283018B6 (cs) * 1991-02-01 1997-12-17 Merck Sharp And Dohme Limited Deriváty imidazolu, triazolu a tetrazolu a farmaceutické přípravky na jejich bázi
PT533268E (pt) * 1991-09-18 2002-02-28 Glaxo Group Ltd Derivados de benzanilida como antagonistas de 5-ht1d
CA2084531A1 (en) * 1991-12-19 1993-06-20 David W. Smith Antimigraine 4-pyrimidinyl and pyridinyl derivatives of indol-3yl-alkyl piperazines
SI9300097B (en) * 1992-02-27 2001-12-31 Janssen Pharmaceutica Nv (benzodioxan, benzofuran or benzopyran) alkylamino) alkyl substituted guanidines
US5521188A (en) * 1993-09-16 1996-05-28 Bristol-Myers Squibb Company Antimigraine cyclobutenedione derivatives of indolylalkyl-pyridinyl and pyrimidinylpiperazines
US5801170A (en) * 1993-12-07 1998-09-01 Smithkline Beecham Plc Heterocyclic biphenylylamides useful as 5HT1D antagonists
SE9504661D0 (sv) 1995-12-22 1995-12-22 Astra Pharma Inc New compounds
AU736510B2 (en) * 1997-06-27 2001-07-26 Nippon Kayaku Kabushiki Kaisha Remedies/preventives for frequent urination/urinary incontinence and tropone derivatives
JP3441636B2 (ja) 1997-11-21 2003-09-02 株式会社エヌ・ティ・ティ・ドコモ チャネル推定値を求める装置および方法、受信装置ならびに伝送システム

Also Published As

Publication number Publication date
WO2002044159A8 (en) 2003-11-20
WO2002044159A3 (en) 2002-08-22
CA2427098A1 (en) 2002-06-06
JP2004517081A (ja) 2004-06-10
US20040067962A1 (en) 2004-04-08
DE60130677T2 (de) 2008-07-17
US6864262B2 (en) 2005-03-08
ATE374192T1 (de) 2007-10-15
DE60130677D1 (de) 2007-11-08
EP1341777A2 (en) 2003-09-10
EP1341777B1 (en) 2007-09-26
WO2002044159A2 (en) 2002-06-06
ES2292636T3 (es) 2008-03-16

Similar Documents

Publication Publication Date Title
EP1450808B8 (en) Quinazoline derivatives for the treatment of t cell mediated diseases
DE60112974D1 (en) Carbolinderivate
NZ545506A (en) Therapeutic agents useful for treating pain
JO2311B1 (en) Alkyl inhibitors Ariel phosphodiesterase-4
BG108269A (en) Pyrazolopyrimidines as therapeutic agents
SE9903760D0 (sv) New compounds
GB0124933D0 (en) Chemical compounds
MXPA04002167A (es) Inhibidores de la 17 beta-hidroxiesteroide deshidrogenasa tipo 3 para el tratamiento de enfermedades androgeno-dependientes.
GB0005251D0 (en) Therapeutic compounds
IL165262A (en) Kinase inhibitors and pharmaceutical compositions containing them
UA74337C2 (uk) Застосування 1-[4-(5-ціаноіндол-3-іл)бутил]-4-(2-карбамоїлбензофуран-5-іл)-піперазину для лікування біполярних розладів та манії
DE60216233D1 (en) Carbolinderivate
AU2001266575A1 (en) Chemical compounds
MXPA03002911A (es) Compuestos quimicos.
AP2003002929A0 (en) Pyrrolopyrimidines as protein kinase inhibitors
DE60205899D1 (en) 1-biaryl-1,8-naphthyridin-4-one als phosphodieseterase-inhibitoren
SE9803518D0 (sv) Novel compounds
TW200508199A (en) Novel compound
MXPA02012713A (es) Combinacion de inhibidores de fructosabisfosfatasas y agentes antidiabeticos, util para el tratamiento de la diabetes.
AU2001263278A1 (en) Cyclic gmp-specific phosphodiesterase inhibitors
WO2004030671A3 (en) Use of 4-amino-quinazolines as anti cancer agents
MXPA02012472A (es) Compuestos quimicos.
AU2002230411A1 (en) 1-(2-m-methanesulfonamidophenylethyl)-4-(m-trifluoromethylphenyl)piperazine and pharmaceutically acceptable salts and solvates thereof and their use in the treatment of incontinence
AU2001274786A1 (en) Method for the treatment of overactive bladder
ZA200405173B (en) 2'-halo-3',5'-dialkoxyphen-1'yl-imino-2-imidazoline derivatives and the use thereof for the treatment of urinary incontinence.