DE60130677D1 - 1-(2-m-methansulfonamidophenylethyl)-4-(m-trifluoromethylphenyl)piperazine und ihre akzeptablen pharmazeutischen salze und solvate und ihre verwendung zur behandlung von inkontinenz - Google Patents
1-(2-m-methansulfonamidophenylethyl)-4-(m-trifluoromethylphenyl)piperazine und ihre akzeptablen pharmazeutischen salze und solvate und ihre verwendung zur behandlung von inkontinenzInfo
- Publication number
- DE60130677D1 DE60130677D1 DE60130677T DE60130677T DE60130677D1 DE 60130677 D1 DE60130677 D1 DE 60130677D1 DE 60130677 T DE60130677 T DE 60130677T DE 60130677 T DE60130677 T DE 60130677T DE 60130677 D1 DE60130677 D1 DE 60130677D1
- Authority
- DE
- Germany
- Prior art keywords
- solvates
- incontinence
- methansulfonamidophenylethyl
- trifluoromethylphenyl
- piperazine
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
- C07D295/12—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly or doubly bound nitrogen atoms
- C07D295/135—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly or doubly bound nitrogen atoms with the ring nitrogen atoms and the substituent nitrogen atoms separated by carbocyclic rings or by carbon chains interrupted by carbocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/10—Drugs for disorders of the urinary system of the bladder
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Urology & Nephrology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US25020300P | 2000-11-29 | 2000-11-29 | |
US250203P | 2000-11-29 | ||
PCT/US2001/042949 WO2002044159A2 (en) | 2000-11-29 | 2001-11-16 | 1-(2-m-methanesulfonamidophenylethyl)-4-(m-trifluoromethylphenyl)piperazine and pharmaceutically acceptable salts and solvates thereof and their use in the treatment of incontinence |
Publications (2)
Publication Number | Publication Date |
---|---|
DE60130677D1 true DE60130677D1 (de) | 2007-11-08 |
DE60130677T2 DE60130677T2 (de) | 2008-07-17 |
Family
ID=22946725
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE60130677T Expired - Fee Related DE60130677T2 (de) | 2000-11-29 | 2001-11-16 | 1-(2-m-methansulfonamidophenylethyl)-4-(m-trifluoromethylphenyl)piperazine und ihre akzeptablen pharmazeutischen salze und solvate und ihre verwendung zur behandlung von inkontinenz |
Country Status (9)
Country | Link |
---|---|
US (1) | US6864262B2 (de) |
EP (1) | EP1341777B1 (de) |
JP (1) | JP2004517081A (de) |
AT (1) | ATE374192T1 (de) |
AU (1) | AU2002230411A1 (de) |
CA (1) | CA2427098A1 (de) |
DE (1) | DE60130677T2 (de) |
ES (1) | ES2292636T3 (de) |
WO (1) | WO2002044159A2 (de) |
Families Citing this family (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
BR112013009004B1 (pt) * | 2010-10-15 | 2022-05-10 | Contera Pharma Aps | Uso de composição farmacêutica ou kit de partes compreendendo combinações de agonistas dereceptor de serotonina |
BR112014025907B1 (pt) | 2012-04-18 | 2023-02-14 | Contera Pharma Aps | Formulação farmacêutica disponível para administração por via oral adequada para manejo aprimorado de transtornos do movimento |
WO2018011181A1 (en) | 2016-07-11 | 2018-01-18 | Contera Pharma Aps | Pulsatile drug delivery system for treating morning akinesia |
Family Cites Families (20)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR1300728A (de) * | 1959-10-20 | 1962-07-02 | ||
BE755015A (fr) | 1969-08-20 | 1971-02-01 | Byk Gulden Lomberg Chem Fab | Piperazinyl-alcoylamino-uraciles substitues par un groupe aryle, leurs ethers et thioethers, ainsi que leur procede de preparation |
BE759371A (fr) | 1969-11-24 | 1971-05-24 | Bristol Myers Co | Azaspirodecanediones heterocycliques et procedes pour leur preparation |
FR2362628A1 (fr) | 1976-08-26 | 1978-03-24 | Roussel Uclaf | Nouveaux derives du piperidyl-indole et leurs sels, procede de preparation et application a titre de medicaments |
US4423049A (en) | 1981-12-28 | 1983-12-27 | Mead Johnson & Company | 2-[4-[(4,4-Dialkyl-2,6-piperidinedion-1-yl)butyl]-1-piperazinyl]pyrimidines |
DE3321969A1 (de) | 1983-06-18 | 1984-12-20 | Troponwerke GmbH & Co KG, 5000 Köln | 2-pyrimidinyl-1-piperazin-derivate, verfahren zu ihrer herstellung und diese enthaltende arzneimittel |
ZA848005B (en) | 1983-10-17 | 1985-05-29 | Duphar Int Res | Blood-pressure lowering piperazine derivatives |
US4997841A (en) | 1987-08-13 | 1991-03-05 | Glaxo Group Limited | Indole derivatives |
KR910700251A (ko) | 1988-12-15 | 1991-03-14 | 원본미기재 | 5-ht 선택제 |
CA2064815C (en) | 1990-06-07 | 1999-11-16 | Alan Duncan Robertson | Therapeutic heterocyclic compounds |
US5545644A (en) | 1990-10-15 | 1996-08-13 | Pfizer Inc. | Indole derivatives |
SK278998B6 (sk) | 1991-02-01 | 1998-05-06 | Merck Sharp & Dohme Limited | Deriváty imidazolu, triazolu a tetrazolu, spôsob i |
ES2162792T3 (es) | 1991-09-18 | 2002-01-16 | Glaxo Group Ltd | Derivados de benzanilida como antagonistas de 5-ht1d. |
CA2084531A1 (en) | 1991-12-19 | 1993-06-20 | David W. Smith | Antimigraine 4-pyrimidinyl and pyridinyl derivatives of indol-3yl-alkyl piperazines |
SI9300097B (en) | 1992-02-27 | 2001-12-31 | Janssen Pharmaceutica Nv | (benzodioxan, benzofuran or benzopyran) alkylamino) alkyl substituted guanidines |
US5521188A (en) | 1993-09-16 | 1996-05-28 | Bristol-Myers Squibb Company | Antimigraine cyclobutenedione derivatives of indolylalkyl-pyridinyl and pyrimidinylpiperazines |
EP0733048A1 (de) | 1993-12-07 | 1996-09-25 | Smithkline Beecham Plc | Heterocyclische biphenylylamide, verwendbar als 5ht1d antagonisten |
SE9504661D0 (sv) | 1995-12-22 | 1995-12-22 | Astra Pharma Inc | New compounds |
AU736510B2 (en) * | 1997-06-27 | 2001-07-26 | Nippon Kayaku Kabushiki Kaisha | Remedies/preventives for frequent urination/urinary incontinence and tropone derivatives |
JP3441636B2 (ja) | 1997-11-21 | 2003-09-02 | 株式会社エヌ・ティ・ティ・ドコモ | チャネル推定値を求める装置および方法、受信装置ならびに伝送システム |
-
2001
- 2001-11-16 EP EP01990644A patent/EP1341777B1/de not_active Expired - Lifetime
- 2001-11-16 AU AU2002230411A patent/AU2002230411A1/en not_active Abandoned
- 2001-11-16 DE DE60130677T patent/DE60130677T2/de not_active Expired - Fee Related
- 2001-11-16 CA CA002427098A patent/CA2427098A1/en not_active Abandoned
- 2001-11-16 ES ES01990644T patent/ES2292636T3/es not_active Expired - Lifetime
- 2001-11-16 US US10/432,413 patent/US6864262B2/en not_active Expired - Fee Related
- 2001-11-16 AT AT01990644T patent/ATE374192T1/de not_active IP Right Cessation
- 2001-11-16 WO PCT/US2001/042949 patent/WO2002044159A2/en active IP Right Grant
- 2001-11-16 JP JP2002546529A patent/JP2004517081A/ja active Pending
Also Published As
Publication number | Publication date |
---|---|
DE60130677T2 (de) | 2008-07-17 |
JP2004517081A (ja) | 2004-06-10 |
EP1341777A2 (de) | 2003-09-10 |
US20040067962A1 (en) | 2004-04-08 |
ES2292636T3 (es) | 2008-03-16 |
WO2002044159A8 (en) | 2003-11-20 |
AU2002230411A1 (en) | 2002-06-11 |
US6864262B2 (en) | 2005-03-08 |
WO2002044159A2 (en) | 2002-06-06 |
CA2427098A1 (en) | 2002-06-06 |
EP1341777B1 (de) | 2007-09-26 |
WO2002044159A3 (en) | 2002-08-22 |
ATE374192T1 (de) | 2007-10-15 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
8364 | No opposition during term of opposition | ||
8328 | Change in the person/name/address of the agent |
Representative=s name: KROHER, STROBEL RECHTS- UND PATENTANWAELTE, 80336 |
|
8339 | Ceased/non-payment of the annual fee |