ES2191464T3 - Tetrahidropiridoeteres. - Google Patents

Tetrahidropiridoeteres.

Info

Publication number
ES2191464T3
ES2191464T3 ES99948776T ES99948776T ES2191464T3 ES 2191464 T3 ES2191464 T3 ES 2191464T3 ES 99948776 T ES99948776 T ES 99948776T ES 99948776 T ES99948776 T ES 99948776T ES 2191464 T3 ES2191464 T3 ES 2191464T3
Authority
ES
Spain
Prior art keywords
hydroxyl
tetrahydropiridoeteres
methoxypropoxy
methoxyethoxy
isopropoxy
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES99948776T
Other languages
English (en)
Spanish (es)
Inventor
Stefan Postius
Wolfgang-Alexander Simon
Gerhard Grundler
Guido Hanauer
Reinhard Huber
Wolfgang Kromer
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Takeda GmbH
Original Assignee
Altana Pharma AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Altana Pharma AG filed Critical Altana Pharma AG
Application granted granted Critical
Publication of ES2191464T3 publication Critical patent/ES2191464T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D471/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/12Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains three hetero rings
    • C07D471/14Ortho-condensed systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/4353Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/4375Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a six-membered ring having nitrogen as a ring heteroatom, e.g. quinolizines, naphthyridines, berberine, vincamine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Communicable Diseases (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Oncology (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pyridine Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
ES99948776T 1998-09-23 1999-09-17 Tetrahidropiridoeteres. Expired - Lifetime ES2191464T3 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE19843504 1998-09-23
EP98117988 1998-09-23

Publications (1)

Publication Number Publication Date
ES2191464T3 true ES2191464T3 (es) 2003-09-01

Family

ID=26049024

Family Applications (1)

Application Number Title Priority Date Filing Date
ES99948776T Expired - Lifetime ES2191464T3 (es) 1998-09-23 1999-09-17 Tetrahidropiridoeteres.

Country Status (31)

Country Link
US (4) US6436953B1 (enExample)
EP (1) EP1115725B1 (enExample)
JP (1) JP4145492B2 (enExample)
KR (1) KR100668400B1 (enExample)
CN (2) CN100506821C (enExample)
AT (1) ATE231862T1 (enExample)
AU (1) AU763463B2 (enExample)
BG (1) BG65195B1 (enExample)
BR (1) BR9914044A (enExample)
CA (1) CA2344251A1 (enExample)
CZ (1) CZ292335B6 (enExample)
DE (1) DE69905178T2 (enExample)
DK (1) DK1115725T3 (enExample)
EA (1) EA005377B1 (enExample)
EE (1) EE04677B1 (enExample)
ES (1) ES2191464T3 (enExample)
GE (1) GEP20032926B (enExample)
HK (1) HK1038360B (enExample)
HR (1) HRP20010224A2 (enExample)
HU (1) HUP0102990A3 (enExample)
ID (1) ID28896A (enExample)
IL (2) IL142063A0 (enExample)
NO (1) NO317304B1 (enExample)
NZ (1) NZ510610A (enExample)
PL (1) PL193616B1 (enExample)
PT (1) PT1115725E (enExample)
RS (1) RS50145B (enExample)
SI (1) SI1115725T1 (enExample)
SK (1) SK285165B6 (enExample)
TR (1) TR200100805T2 (enExample)
WO (1) WO2000017200A1 (enExample)

Families Citing this family (36)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6436953B1 (en) * 1998-09-23 2002-08-20 Byk Gulden Lomberg Chemische Fabrik Gmbh Tetrahydropyridoethers
AU3966600A (en) 1999-04-17 2000-11-02 Byk Gulden Lomberg Chemische Fabrik Gmbh Haloalkoxy imidazonaphthyridines
CA2285516C (en) * 1999-05-12 2010-12-07 President And Fellows Of Harvard College Dopamine transporter imaging agents
PL365165A1 (en) * 2000-03-29 2004-12-27 Altana Pharma Ag Tricyclic imidazopyridines
CZ20023194A3 (cs) * 2000-03-29 2003-01-15 Altana Pharma Ag Prekursory imidazopyridinových derivátů
AU1056302A (en) * 2000-10-25 2002-05-06 Byk Gulden Lomberg Chem Fab Polysubstituted imidazopyridines as gastric secretion inhibitors
UA80393C2 (uk) 2000-12-07 2007-09-25 Алтана Фарма Аг Фармацевтична композиція, яка містить інгібітор фде 4, диспергований в матриці
US20040082605A1 (en) * 2001-03-08 2004-04-29 Arne Eek Use
CA2452802A1 (en) 2001-08-02 2003-02-20 Altana Pharma Ag Tricyclic epoxides
MXPA04001048A (es) * 2001-08-03 2004-05-20 Altana Pharma Ag Imidazopiridinas sustituidas con alquilo, para el tratamiento de trastornos gastrointestinales.
WO2003014120A1 (en) * 2001-08-03 2003-02-20 Altana Pharma Ag Amino-substituted imidazopyridines for the treatment of gastrointestinal diseases
JP2005519933A (ja) 2002-02-15 2005-07-07 アルタナ ファルマ アクチエンゲゼルシャフト 三環式n−アシル化合物
MY140561A (en) 2002-02-20 2009-12-31 Nycomed Gmbh Dosage form containing pde 4 inhibitor as active ingredient
HRP20041160A2 (en) * 2002-05-07 2005-08-31 Altana Pharma Ag Novel combination for the treatment of airway disorders
EA008304B1 (ru) 2002-11-19 2007-04-27 Алтана Фарма Аг 8-замещённые имидазопиридины
WO2004052374A1 (en) 2002-12-12 2004-06-24 Altana Pharma Ag Combination medicament
EA010107B1 (ru) * 2002-12-20 2008-06-30 Алтана Фарма Аг Силиловые простые эфиры
RS20050603A (sr) * 2003-02-17 2007-09-21 Altana Pharma Ag., NOVE KOMBINACIJE I NOVA PRIMENA FARMACEUTSKIH AKTIVNIH JEDINjENjA
ES2335498T3 (es) 2003-03-10 2010-03-29 Nycomed Gmbh Nuevo proceso para la preparacion de reflumilast.
TW200503783A (en) * 2003-04-11 2005-02-01 Altana Pharma Ag Oral pharmaceutical preparation for proton pump antagonists
SA04250092B1 (ar) * 2003-05-14 2008-05-04 التانا فاروا ايه جي مركب وسيط جديد لتحضير مركبات إيميدازوبيريدين imidazopyridines فعالة علاجياً
MXPA05012463A (es) * 2003-05-27 2006-01-30 Altana Pharma Ag Combinaciones farmaceuticas de un inhibidor de bomba protonica y un compuesto que modifica la motilidad gastrointestinal.
JP2007507425A (ja) * 2003-08-29 2007-03-29 ダイノゲン ファーマシューティカルズ,インコーポレイテッド 胃腸管運動障害を処置するために有用な組成物
PL1670482T5 (pl) 2003-09-16 2022-10-03 Covis Pharma Gmbh Zastosowanie cyklezonidu w leczeniu chorób układu oddechowego
CA2544325A1 (en) * 2003-11-03 2005-05-12 Astrazeneca Ab Imidazo [1,2-a] pyridine derivatives for the treatment of silent gastro-esophageal reflux
EP1697358A1 (en) 2003-12-19 2006-09-06 Altana Pharma AG Intermediates for the preparation of tricyclic dihydropyrano -imidazo -pyridines derivatives
AR047605A1 (es) * 2004-02-17 2006-01-25 Altana Pharma Ag Imidazopiridinas triciclicas e intermediarios en la sintesis de las mismas,sus procesos de preparacion,composiciones farmaceuticas que los contienen y usos.
KR100958829B1 (ko) 2004-09-03 2010-05-25 주식회사유한양행 피롤로[2,3-c]피리딘 유도체 및 그의 제조방법
MX2007002219A (es) 2004-09-03 2007-05-04 Yuhan Corp Derivados de pirrolo [3,2-b ] piridina y procesos para su preparacion.
EP1784402B1 (en) 2004-09-03 2011-08-03 Yuhan Corporation PYRROLO[3,2-c]PYRIDINE DERIVATIVES AND PROCESSES FOR THE PREPARATION THEREOF
EP2258350B1 (en) * 2005-03-16 2014-12-24 Takeda GmbH Taste masked dosage form containing roflumilast
EP2080513A1 (en) 2008-01-16 2009-07-22 Schraermeyer, Ulrich, Prof. Dr. rer. nat Tetrahydropyridoethers for treatment of AMD
MX2012000275A (es) 2009-07-09 2012-02-08 Raqualia Pharma Inc Antagonista de bomba de acido para el tratamiento de enfermedades involucradas en la motilidad gastrointestinal anormal.
WO2012027240A1 (en) * 2010-08-23 2012-03-01 Schering Corporation Fused tricyclic inhibitors of mammalian target of rapamycin
EP2861571B1 (en) * 2012-06-15 2017-05-03 Bio-Pharm Solutions Co., Ltd. Phenylalkyl sulfamate compound and muscle relaxant composition comprising the same
WO2015052256A1 (en) 2013-10-08 2015-04-16 Katairo Gmbh Tetrahydropyridoethers for the treatment of stargardt's disease

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4468400A (en) * 1982-12-20 1984-08-28 Schering Corporation Antiulcer tricyclic imidazo [1,2-a]pyridines
HU204828B (en) 1987-07-16 1992-02-28 Byk Gulden Lomberg Chem Fab Process for producing new diazole derivatives and pharmaceutical compositions comprising such compounds
SE9401197D0 (sv) * 1994-04-11 1994-04-11 Astra Ab Active compounds
CA2196076A1 (en) * 1994-07-28 1996-02-08 Gerhard Grundler Acyl imidazopyridines
SK283288B6 (sk) * 1997-03-24 2003-05-02 Altana Pharma Ag Tetrahydropyridínové zlúčeniny, farmaceutický prostriedok s ich obsahom a ich použitie
WO1998042707A1 (en) * 1997-03-24 1998-10-01 Byk Gulden Lomberg Chemische Fabrik Gmbh Tetrahydropyrido compounds
US6436953B1 (en) 1998-09-23 2002-08-20 Byk Gulden Lomberg Chemische Fabrik Gmbh Tetrahydropyridoethers

Also Published As

Publication number Publication date
PL193616B1 (pl) 2007-02-28
DE69905178D1 (de) 2003-03-06
YU21401A (sh) 2004-03-12
CN1560055A (zh) 2005-01-05
BG105270A (en) 2001-11-30
HK1038360B (en) 2003-05-16
CN1155598C (zh) 2004-06-30
RS50145B (sr) 2009-03-25
US6436953B1 (en) 2002-08-20
EE04677B1 (et) 2006-08-15
TR200100805T2 (tr) 2001-08-21
HUP0102990A2 (hu) 2002-01-28
US20020169320A1 (en) 2002-11-14
US7393860B1 (en) 2008-07-01
US6696460B2 (en) 2004-02-24
EA005377B1 (ru) 2005-02-24
WO2000017200A1 (en) 2000-03-30
CN100506821C (zh) 2009-07-01
IL142063A (en) 2007-10-31
US7105676B2 (en) 2006-09-12
NZ510610A (en) 2003-07-25
NO20011243D0 (no) 2001-03-12
SI1115725T1 (en) 2003-06-30
HUP0102990A3 (en) 2002-09-30
BR9914044A (pt) 2001-12-04
SK285165B6 (sk) 2006-07-07
JP4145492B2 (ja) 2008-09-03
ID28896A (id) 2001-07-12
CN1319101A (zh) 2001-10-24
KR100668400B1 (ko) 2007-01-17
CZ20011082A3 (cs) 2001-09-12
BG65195B1 (bg) 2007-06-29
HRP20010224A2 (en) 2002-04-30
PL346617A1 (en) 2002-02-25
GEP20032926B (en) 2003-03-25
PT1115725E (pt) 2003-06-30
EE200100172A (et) 2002-06-17
EP1115725B1 (en) 2003-01-29
DK1115725T3 (da) 2003-06-23
US20040162310A1 (en) 2004-08-19
ATE231862T1 (de) 2003-02-15
NO317304B1 (no) 2004-10-04
EP1115725A1 (en) 2001-07-18
SK3992001A3 (en) 2001-12-03
CZ292335B6 (cs) 2003-09-17
EA200100315A1 (ru) 2001-10-22
KR20010075223A (ko) 2001-08-09
IL142063A0 (en) 2002-03-10
AU763463B2 (en) 2003-07-24
JP2002526499A (ja) 2002-08-20
NO20011243L (no) 2001-03-12
CA2344251A1 (en) 2000-03-30
DE69905178T2 (de) 2003-07-17
HK1038360A1 (en) 2002-03-15
AU6192099A (en) 2000-04-10

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