ES2191464T3 - Tetrahidropiridoeteres. - Google Patents

Tetrahidropiridoeteres.

Info

Publication number
ES2191464T3
ES2191464T3 ES99948776T ES99948776T ES2191464T3 ES 2191464 T3 ES2191464 T3 ES 2191464T3 ES 99948776 T ES99948776 T ES 99948776T ES 99948776 T ES99948776 T ES 99948776T ES 2191464 T3 ES2191464 T3 ES 2191464T3
Authority
ES
Spain
Prior art keywords
hydroxyl
tetrahydropiridoeteres
methoxypropoxy
methoxyethoxy
isopropoxy
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES99948776T
Other languages
English (en)
Spanish (es)
Inventor
Stefan Postius
Wolfgang-Alexander Simon
Gerhard Grundler
Guido Hanauer
Reinhard Huber
Wolfgang Kromer
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Takeda GmbH
Original Assignee
Altana Pharma AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Altana Pharma AG filed Critical Altana Pharma AG
Application granted granted Critical
Publication of ES2191464T3 publication Critical patent/ES2191464T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/12—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains three hetero rings
    • C07D471/14—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/4353—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/4375—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a six-membered ring having nitrogen as a ring heteroatom, e.g. quinolizines, naphthyridines, berberine, vincamine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Communicable Diseases (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Oncology (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pyridine Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)
ES99948776T 1998-09-23 1999-09-17 Tetrahidropiridoeteres. Expired - Lifetime ES2191464T3 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP98117988 1998-09-23
DE19843504 1998-09-23

Publications (1)

Publication Number Publication Date
ES2191464T3 true ES2191464T3 (es) 2003-09-01

Family

ID=26049024

Family Applications (1)

Application Number Title Priority Date Filing Date
ES99948776T Expired - Lifetime ES2191464T3 (es) 1998-09-23 1999-09-17 Tetrahidropiridoeteres.

Country Status (31)

Country Link
US (4) US6436953B1 (enExample)
EP (1) EP1115725B1 (enExample)
JP (1) JP4145492B2 (enExample)
KR (1) KR100668400B1 (enExample)
CN (2) CN1155598C (enExample)
AT (1) ATE231862T1 (enExample)
AU (1) AU763463B2 (enExample)
BG (1) BG65195B1 (enExample)
BR (1) BR9914044A (enExample)
CA (1) CA2344251A1 (enExample)
CZ (1) CZ292335B6 (enExample)
DE (1) DE69905178T2 (enExample)
DK (1) DK1115725T3 (enExample)
EA (1) EA005377B1 (enExample)
EE (1) EE04677B1 (enExample)
ES (1) ES2191464T3 (enExample)
GE (1) GEP20032926B (enExample)
HK (1) HK1038360B (enExample)
HR (1) HRP20010224A2 (enExample)
HU (1) HUP0102990A3 (enExample)
ID (1) ID28896A (enExample)
IL (2) IL142063A0 (enExample)
NO (1) NO317304B1 (enExample)
NZ (1) NZ510610A (enExample)
PL (1) PL193616B1 (enExample)
PT (1) PT1115725E (enExample)
RS (1) RS50145B (enExample)
SI (1) SI1115725T1 (enExample)
SK (1) SK285165B6 (enExample)
TR (1) TR200100805T2 (enExample)
WO (1) WO2000017200A1 (enExample)

Families Citing this family (36)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2000017200A1 (en) 1998-09-23 2000-03-30 Byk Gulden Lomberg Chemische Fabrik Gmbh Tetrahydropyridoethers
AU3966600A (en) * 1999-04-17 2000-11-02 Byk Gulden Lomberg Chemische Fabrik Gmbh Haloalkoxy imidazonaphthyridines
CA2721484A1 (en) * 1999-05-12 2000-11-12 President And Fellows Of Harvard College Dopamine transporter imaging agents
WO2001072757A1 (en) * 2000-03-29 2001-10-04 Altana Pharma Ag Tricyclic imidazopyridines
JP2003528878A (ja) * 2000-03-29 2003-09-30 アルタナ ファルマ アクチエンゲゼルシャフト イミダゾピリジン誘導体のプロドラッグ
AU2002210563B2 (en) * 2000-10-25 2007-03-01 Altana Pharma Ag Polysubstituted imidazopyridines as gastric secretion inhibitors
UA80393C2 (uk) 2000-12-07 2007-09-25 Алтана Фарма Аг Фармацевтична композиція, яка містить інгібітор фде 4, диспергований в матриці
CZ20032398A3 (cs) * 2001-03-08 2004-02-18 Astrazeneca Ab Nové použití derivátů 6-karboxamidoimidazo [1,2-a] pyridinu
ATE336493T1 (de) 2001-08-02 2006-09-15 Altana Pharma Ag Tricyclische epoxide
CN1656096A (zh) * 2001-08-03 2005-08-17 奥坦纳医药公司 用于治疗胃肠病症的烷基-取代的咪唑吡啶
US20040235882A1 (en) * 2001-08-03 2004-11-25 Jorg Senn-Bilfinger Amino-substituted imidazopyridines for the treatment of gastrointestial diseases
HRP20040834A2 (en) 2002-02-15 2005-06-30 Altana Pharma Ag Tricyclic n-acyl compounds
MY140561A (en) * 2002-02-20 2009-12-31 Nycomed Gmbh Dosage form containing pde 4 inhibitor as active ingredient
WO2003094967A2 (en) * 2002-05-07 2003-11-20 Altana Pharma Ag New combination of reversible proton pump inhibitors and airway therapeutics for treating airway disorders
HRP20050528A2 (en) 2002-11-19 2006-06-30 Altana Pharma Ag 8-substituted imidazopyridines
ES2312844T3 (es) 2002-12-12 2009-03-01 Nycomed Gmbh Medicamento de combinacion de r, r-formoterol y ciclesonida.
PL375933A1 (en) * 2002-12-20 2005-12-12 Altana Pharma Ag 8-trialkylsiloxy-2-methyl-9-phenyl-7-oxo-7,8,9,10-tetrahydroimidazo[1,2-h][1,7]naphthyridines
BRPI0407541A (pt) * 2003-02-17 2006-02-14 Altana Pharma Ag combinações e uso de compostos farmaceuticamente ativos selecionados
EA009985B1 (ru) 2003-03-10 2008-04-28 Никомед Гмбх Новый способ получения рофлумиласта
TW200503783A (en) * 2003-04-11 2005-02-01 Altana Pharma Ag Oral pharmaceutical preparation for proton pump antagonists
SA04250092B1 (ar) * 2003-05-14 2008-05-04 التانا فاروا ايه جي مركب وسيط جديد لتحضير مركبات إيميدازوبيريدين imidazopyridines فعالة علاجياً
CA2526566A1 (en) * 2003-05-27 2004-12-09 Altana Pharma Ag Pharmaceutical combinations of a proton pump inhibitor and a compound which modifies gastrointestinal motility
CA2537182A1 (en) * 2003-08-29 2005-03-10 Dynogen Pharmaceuticals, Inc. Compositions useful for treating gastrointestinal motility disorders
WO2005025578A1 (en) 2003-09-16 2005-03-24 Altana Pharma Ag Use of ciclesonide for the treatment of respiratory diseases
EP1682133A1 (en) * 2003-11-03 2006-07-26 AstraZeneca AB Imidazo 1,2-a pyridine derivatives for the treatment of silent gastro-esophageal reflux
WO2005058894A1 (en) 2003-12-19 2005-06-30 Altana Pharma Ag Intermediates for the preparation of tricyclic dihydropyrano -imidazo -pyridines derivatives
AR047605A1 (es) * 2004-02-17 2006-01-25 Altana Pharma Ag Imidazopiridinas triciclicas e intermediarios en la sintesis de las mismas,sus procesos de preparacion,composiciones farmaceuticas que los contienen y usos.
DK1784404T3 (da) 2004-09-03 2012-02-13 Yuhan Corp Pyrrolo[2,3-c]pyridinderivater samt fremgangsmåder til deres fremstilling
DK1784402T3 (da) 2004-09-03 2011-11-14 Yuhan Corp Pyrrolo[3,2-c]pyridinderivater samt fremgangsmåder til deres fremstilling
ES2426920T3 (es) 2004-09-03 2013-10-25 Yuhan Corporation Derivados de pirrolo[3,2-B]piridina y procesos para su preparación
ES2421916T3 (es) * 2005-03-16 2013-09-06 Nycomed Gmbh Forma farmacéutica de sabor enmascarado que contiene roflumilast
EP2080513A1 (en) 2008-01-16 2009-07-22 Schraermeyer, Ulrich, Prof. Dr. rer. nat Tetrahydropyridoethers for treatment of AMD
EP2452680B1 (en) 2009-07-09 2019-12-18 RaQualia Pharma Inc. Acid pump antagonist for the treatment of diseases involved in abnormal gastrointestinal motility
WO2012027240A1 (en) * 2010-08-23 2012-03-01 Schering Corporation Fused tricyclic inhibitors of mammalian target of rapamycin
BR112014031396B1 (pt) * 2012-06-15 2019-11-26 Bio Pharm Solutions Co Ltd composto de sulfamato de fenilalquila e composição de relaxante muscular compreendendo o mesmo
US20160235724A1 (en) 2013-10-08 2016-08-18 Katairo Gmbh Tetrahydropyridoethers for the treatment of stargardt's disease

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4468400A (en) * 1982-12-20 1984-08-28 Schering Corporation Antiulcer tricyclic imidazo [1,2-a]pyridines
EP0370056A1 (de) 1987-07-16 1990-05-30 Byk Gulden Lomberg Chemische Fabrik Gmbh Neue diazole
SE9401197D0 (sv) * 1994-04-11 1994-04-11 Astra Ab Active compounds
JPH10505332A (ja) * 1994-07-28 1998-05-26 ビイク グルデン ロンベルク ヒェーミッシェ ファブリーク ゲゼルシャフト ミット ベシュレンクテル ハフツング アシルイミダゾピリジン
BR9807883A (pt) * 1997-03-24 2000-02-22 Byk Gulden Lomberg Chem Fab Compostos de tetraidropirido
HUP0001555A3 (en) * 1997-10-30 2001-01-29 Altana Pharma Ag Tetrahydro-imidazo-naphthyridine derivatives, pharmaceutical compositions thereof and process for their preparation
WO2000017200A1 (en) 1998-09-23 2000-03-30 Byk Gulden Lomberg Chemische Fabrik Gmbh Tetrahydropyridoethers

Also Published As

Publication number Publication date
ID28896A (id) 2001-07-12
US20020169320A1 (en) 2002-11-14
EP1115725A1 (en) 2001-07-18
CZ20011082A3 (cs) 2001-09-12
KR20010075223A (ko) 2001-08-09
NO317304B1 (no) 2004-10-04
EA200100315A1 (ru) 2001-10-22
BG65195B1 (bg) 2007-06-29
IL142063A (en) 2007-10-31
NO20011243L (no) 2001-03-12
GEP20032926B (en) 2003-03-25
EE04677B1 (et) 2006-08-15
US6696460B2 (en) 2004-02-24
NO20011243D0 (no) 2001-03-12
HK1038360B (en) 2003-05-16
EA005377B1 (ru) 2005-02-24
SI1115725T1 (en) 2003-06-30
US6436953B1 (en) 2002-08-20
BR9914044A (pt) 2001-12-04
AU6192099A (en) 2000-04-10
JP2002526499A (ja) 2002-08-20
HUP0102990A2 (hu) 2002-01-28
PT1115725E (pt) 2003-06-30
IL142063A0 (en) 2002-03-10
SK3992001A3 (en) 2001-12-03
CN1319101A (zh) 2001-10-24
NZ510610A (en) 2003-07-25
CN100506821C (zh) 2009-07-01
AU763463B2 (en) 2003-07-24
CN1155598C (zh) 2004-06-30
SK285165B6 (sk) 2006-07-07
KR100668400B1 (ko) 2007-01-17
BG105270A (en) 2001-11-30
WO2000017200A1 (en) 2000-03-30
DK1115725T3 (da) 2003-06-23
TR200100805T2 (tr) 2001-08-21
EP1115725B1 (en) 2003-01-29
CA2344251A1 (en) 2000-03-30
YU21401A (sh) 2004-03-12
JP4145492B2 (ja) 2008-09-03
DE69905178D1 (de) 2003-03-06
HK1038360A1 (en) 2002-03-15
PL346617A1 (en) 2002-02-25
US7105676B2 (en) 2006-09-12
RS50145B (sr) 2009-03-25
HUP0102990A3 (en) 2002-09-30
US20040162310A1 (en) 2004-08-19
EE200100172A (et) 2002-06-17
CZ292335B6 (cs) 2003-09-17
ATE231862T1 (de) 2003-02-15
DE69905178T2 (de) 2003-07-17
CN1560055A (zh) 2005-01-05
HRP20010224A2 (en) 2002-04-30
US7393860B1 (en) 2008-07-01
PL193616B1 (pl) 2007-02-28

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