ES2183827T5 - Dispositivo y metodo para el agotamiento del contenido en leucocitos de productos de sangre. - Google Patents
Dispositivo y metodo para el agotamiento del contenido en leucocitos de productos de sangre. Download PDFInfo
- Publication number
- ES2183827T5 ES2183827T5 ES94201693T ES94201693T ES2183827T5 ES 2183827 T5 ES2183827 T5 ES 2183827T5 ES 94201693 T ES94201693 T ES 94201693T ES 94201693 T ES94201693 T ES 94201693T ES 2183827 T5 ES2183827 T5 ES 2183827T5
- Authority
- ES
- Spain
- Prior art keywords
- examples
- fibers
- blood
- micrometers
- prc
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- 239000010836 blood and blood product Substances 0.000 title claims abstract description 22
- 229940125691 blood product Drugs 0.000 title claims abstract description 22
- 238000000034 method Methods 0.000 title claims description 34
- 210000000265 leukocyte Anatomy 0.000 claims abstract description 116
- 239000000835 fiber Substances 0.000 claims description 152
- 239000010410 layer Substances 0.000 claims description 91
- 239000011148 porous material Substances 0.000 claims description 91
- 229920001707 polybutylene terephthalate Polymers 0.000 claims description 20
- 229920002994 synthetic fiber Polymers 0.000 claims description 12
- 239000012209 synthetic fiber Substances 0.000 claims description 12
- 239000002356 single layer Substances 0.000 claims description 8
- 238000012986 modification Methods 0.000 claims description 6
- 230000004048 modification Effects 0.000 claims description 6
- 230000005855 radiation Effects 0.000 claims description 6
- 230000000779 depleting effect Effects 0.000 claims description 2
- 238000001914 filtration Methods 0.000 abstract description 21
- 230000008030 elimination Effects 0.000 abstract description 15
- 238000003379 elimination reaction Methods 0.000 abstract description 15
- 238000010521 absorption reaction Methods 0.000 abstract description 5
- 210000004369 blood Anatomy 0.000 description 126
- 239000008280 blood Substances 0.000 description 126
- 239000000499 gel Substances 0.000 description 85
- 210000003743 erythrocyte Anatomy 0.000 description 67
- 238000001179 sorption measurement Methods 0.000 description 59
- 238000011045 prefiltration Methods 0.000 description 53
- 239000012530 fluid Substances 0.000 description 41
- 238000012360 testing method Methods 0.000 description 41
- 239000007788 liquid Substances 0.000 description 32
- 230000014759 maintenance of location Effects 0.000 description 32
- 230000004087 circulation Effects 0.000 description 28
- 239000000463 material Substances 0.000 description 27
- 230000004308 accommodation Effects 0.000 description 21
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 19
- 230000006399 behavior Effects 0.000 description 17
- 239000000306 component Substances 0.000 description 17
- 210000002381 plasma Anatomy 0.000 description 16
- 230000006835 compression Effects 0.000 description 15
- 238000007906 compression Methods 0.000 description 15
- 230000037452 priming Effects 0.000 description 15
- 238000011144 upstream manufacturing Methods 0.000 description 15
- 238000009736 wetting Methods 0.000 description 15
- 210000000601 blood cell Anatomy 0.000 description 12
- 230000006870 function Effects 0.000 description 12
- 238000011161 development Methods 0.000 description 11
- 238000005534 hematocrit Methods 0.000 description 11
- 229920000728 polyester Polymers 0.000 description 11
- 229920000139 polyethylene terephthalate Polymers 0.000 description 11
- 230000002829 reductive effect Effects 0.000 description 11
- 229920005989 resin Polymers 0.000 description 11
- 239000011347 resin Substances 0.000 description 11
- 239000004094 surface-active agent Substances 0.000 description 11
- 239000005020 polyethylene terephthalate Substances 0.000 description 10
- 239000000243 solution Substances 0.000 description 10
- 239000000725 suspension Substances 0.000 description 10
- 238000006243 chemical reaction Methods 0.000 description 9
- 230000000694 effects Effects 0.000 description 9
- 238000013461 design Methods 0.000 description 8
- 238000004519 manufacturing process Methods 0.000 description 8
- 239000002245 particle Substances 0.000 description 8
- 230000007246 mechanism Effects 0.000 description 7
- 238000000926 separation method Methods 0.000 description 7
- 238000003860 storage Methods 0.000 description 7
- KFZMGEQAYNKOFK-UHFFFAOYSA-N Isopropanol Chemical compound CC(C)O KFZMGEQAYNKOFK-UHFFFAOYSA-N 0.000 description 6
- FAPWRFPIFSIZLT-UHFFFAOYSA-M Sodium chloride Chemical compound [Na+].[Cl-] FAPWRFPIFSIZLT-UHFFFAOYSA-M 0.000 description 6
- 230000000712 assembly Effects 0.000 description 6
- 238000000429 assembly Methods 0.000 description 6
- 230000008901 benefit Effects 0.000 description 6
- 210000004027 cell Anatomy 0.000 description 6
- 238000005119 centrifugation Methods 0.000 description 6
- 210000003714 granulocyte Anatomy 0.000 description 6
- 238000005259 measurement Methods 0.000 description 6
- 230000000717 retained effect Effects 0.000 description 6
- 239000003146 anticoagulant agent Substances 0.000 description 5
- 229940127219 anticoagulant drug Drugs 0.000 description 5
- 239000012503 blood component Substances 0.000 description 5
- 239000003795 chemical substances by application Substances 0.000 description 5
- 238000010276 construction Methods 0.000 description 5
- 230000003111 delayed effect Effects 0.000 description 5
- 239000000178 monomer Substances 0.000 description 5
- -1 poly (tetrafluoroethylene) Polymers 0.000 description 5
- 238000011084 recovery Methods 0.000 description 5
- 102000008946 Fibrinogen Human genes 0.000 description 4
- 108010049003 Fibrinogen Proteins 0.000 description 4
- WOBHKFSMXKNTIM-UHFFFAOYSA-N Hydroxyethyl methacrylate Chemical compound CC(=C)C(=O)OCCO WOBHKFSMXKNTIM-UHFFFAOYSA-N 0.000 description 4
- NIXOWILDQLNWCW-UHFFFAOYSA-N acrylic acid group Chemical group C(C=C)(=O)O NIXOWILDQLNWCW-UHFFFAOYSA-N 0.000 description 4
- 238000000071 blow moulding Methods 0.000 description 4
- 230000015271 coagulation Effects 0.000 description 4
- 238000005345 coagulation Methods 0.000 description 4
- 229940012952 fibrinogen Drugs 0.000 description 4
- 210000004698 lymphocyte Anatomy 0.000 description 4
- 239000004033 plastic Substances 0.000 description 4
- 229920003023 plastic Polymers 0.000 description 4
- 229920000642 polymer Polymers 0.000 description 4
- 239000000843 powder Substances 0.000 description 4
- 210000003462 vein Anatomy 0.000 description 4
- QTBSBXVTEAMEQO-UHFFFAOYSA-N Acetic acid Chemical compound CC(O)=O QTBSBXVTEAMEQO-UHFFFAOYSA-N 0.000 description 3
- 102100026735 Coagulation factor VIII Human genes 0.000 description 3
- 102000009123 Fibrin Human genes 0.000 description 3
- 108010073385 Fibrin Proteins 0.000 description 3
- BWGVNKXGVNDBDI-UHFFFAOYSA-N Fibrin monomer Chemical compound CNC(=O)CNC(=O)CN BWGVNKXGVNDBDI-UHFFFAOYSA-N 0.000 description 3
- 101000911390 Homo sapiens Coagulation factor VIII Proteins 0.000 description 3
- 238000003490 calendering Methods 0.000 description 3
- 229920002301 cellulose acetate Polymers 0.000 description 3
- 230000008859 change Effects 0.000 description 3
- 239000012141 concentrate Substances 0.000 description 3
- 230000001419 dependent effect Effects 0.000 description 3
- 201000010099 disease Diseases 0.000 description 3
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 3
- 238000009826 distribution Methods 0.000 description 3
- 229950003499 fibrin Drugs 0.000 description 3
- 208000015181 infectious disease Diseases 0.000 description 3
- 230000001788 irregular Effects 0.000 description 3
- 239000000314 lubricant Substances 0.000 description 3
- 229920001343 polytetrafluoroethylene Polymers 0.000 description 3
- 230000009467 reduction Effects 0.000 description 3
- 238000007789 sealing Methods 0.000 description 3
- 239000007787 solid Substances 0.000 description 3
- 239000003634 thrombocyte concentrate Substances 0.000 description 3
- 206010053567 Coagulopathies Diseases 0.000 description 2
- 229920000742 Cotton Polymers 0.000 description 2
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 description 2
- BAPJBEWLBFYGME-UHFFFAOYSA-N Methyl acrylate Chemical compound COC(=O)C=C BAPJBEWLBFYGME-UHFFFAOYSA-N 0.000 description 2
- 239000004952 Polyamide Substances 0.000 description 2
- 239000004743 Polypropylene Substances 0.000 description 2
- 239000000654 additive Substances 0.000 description 2
- 230000000996 additive effect Effects 0.000 description 2
- 239000000853 adhesive Substances 0.000 description 2
- 230000001070 adhesive effect Effects 0.000 description 2
- 238000003556 assay Methods 0.000 description 2
- 238000004364 calculation method Methods 0.000 description 2
- 230000035602 clotting Effects 0.000 description 2
- 239000000356 contaminant Substances 0.000 description 2
- 230000007423 decrease Effects 0.000 description 2
- 239000004744 fabric Substances 0.000 description 2
- 230000006872 improvement Effects 0.000 description 2
- 230000036512 infertility Effects 0.000 description 2
- 239000000203 mixture Substances 0.000 description 2
- VLKZOEOYAKHREP-UHFFFAOYSA-N n-Hexane Chemical compound CCCCCC VLKZOEOYAKHREP-UHFFFAOYSA-N 0.000 description 2
- 235000016709 nutrition Nutrition 0.000 description 2
- 229920001778 nylon Polymers 0.000 description 2
- 230000003647 oxidation Effects 0.000 description 2
- 238000007254 oxidation reaction Methods 0.000 description 2
- 229920000058 polyacrylate Polymers 0.000 description 2
- 229920002647 polyamide Polymers 0.000 description 2
- 229920001155 polypropylene Polymers 0.000 description 2
- 238000002360 preparation method Methods 0.000 description 2
- 230000008569 process Effects 0.000 description 2
- 238000012545 processing Methods 0.000 description 2
- 102000004169 proteins and genes Human genes 0.000 description 2
- 108090000623 proteins and genes Proteins 0.000 description 2
- 238000011160 research Methods 0.000 description 2
- 238000007493 shaping process Methods 0.000 description 2
- VWDWKYIASSYTQR-UHFFFAOYSA-N sodium nitrate Chemical compound [Na+].[O-][N+]([O-])=O VWDWKYIASSYTQR-UHFFFAOYSA-N 0.000 description 2
- 239000007858 starting material Substances 0.000 description 2
- 230000003068 static effect Effects 0.000 description 2
- 239000000126 substance Substances 0.000 description 2
- 229920003002 synthetic resin Polymers 0.000 description 2
- 239000000057 synthetic resin Substances 0.000 description 2
- 230000003612 virological effect Effects 0.000 description 2
- 238000005406 washing Methods 0.000 description 2
- 238000005303 weighing Methods 0.000 description 2
- 229940044192 2-hydroxyethyl methacrylate Drugs 0.000 description 1
- 208000035143 Bacterial infection Diseases 0.000 description 1
- UXVMQQNJUSDDNG-UHFFFAOYSA-L Calcium chloride Chemical compound [Cl-].[Cl-].[Ca+2] UXVMQQNJUSDDNG-UHFFFAOYSA-L 0.000 description 1
- 241000701022 Cytomegalovirus Species 0.000 description 1
- 206010011831 Cytomegalovirus infection Diseases 0.000 description 1
- 206010018910 Haemolysis Diseases 0.000 description 1
- VVQNEPGJFQJSBK-UHFFFAOYSA-N Methyl methacrylate Chemical compound COC(=O)C(C)=C VVQNEPGJFQJSBK-UHFFFAOYSA-N 0.000 description 1
- 206010028980 Neoplasm Diseases 0.000 description 1
- 239000002033 PVDF binder Substances 0.000 description 1
- RVGRUAULSDPKGF-UHFFFAOYSA-N Poloxamer Chemical compound C1CO1.CC1CO1 RVGRUAULSDPKGF-UHFFFAOYSA-N 0.000 description 1
- 239000004698 Polyethylene Substances 0.000 description 1
- HEMHJVSKTPXQMS-UHFFFAOYSA-M Sodium hydroxide Chemical compound [OH-].[Na+] HEMHJVSKTPXQMS-UHFFFAOYSA-M 0.000 description 1
- 208000002903 Thalassemia Diseases 0.000 description 1
- 208000007536 Thrombosis Diseases 0.000 description 1
- 208000036142 Viral infection Diseases 0.000 description 1
- 238000009825 accumulation Methods 0.000 description 1
- 239000002253 acid Substances 0.000 description 1
- 229920006397 acrylic thermoplastic Polymers 0.000 description 1
- 230000003213 activating effect Effects 0.000 description 1
- 230000002411 adverse Effects 0.000 description 1
- 230000004520 agglutination Effects 0.000 description 1
- 230000004075 alteration Effects 0.000 description 1
- 238000013459 approach Methods 0.000 description 1
- 230000001174 ascending effect Effects 0.000 description 1
- 230000002238 attenuated effect Effects 0.000 description 1
- 208000022362 bacterial infectious disease Diseases 0.000 description 1
- 239000011230 binding agent Substances 0.000 description 1
- 230000033228 biological regulation Effects 0.000 description 1
- 230000000903 blocking effect Effects 0.000 description 1
- 230000017531 blood circulation Effects 0.000 description 1
- 238000004820 blood count Methods 0.000 description 1
- 230000036772 blood pressure Effects 0.000 description 1
- BTANRVKWQNVYAZ-UHFFFAOYSA-N butan-2-ol Chemical compound CCC(C)O BTANRVKWQNVYAZ-UHFFFAOYSA-N 0.000 description 1
- 239000001110 calcium chloride Substances 0.000 description 1
- 229910001628 calcium chloride Inorganic materials 0.000 description 1
- 201000011510 cancer Diseases 0.000 description 1
- 125000003178 carboxy group Chemical group [H]OC(*)=O 0.000 description 1
- 206010061592 cardiac fibrillation Diseases 0.000 description 1
- 239000000969 carrier Substances 0.000 description 1
- 230000015556 catabolic process Effects 0.000 description 1
- 239000006285 cell suspension Substances 0.000 description 1
- 238000012512 characterization method Methods 0.000 description 1
- 239000011248 coating agent Substances 0.000 description 1
- 238000000576 coating method Methods 0.000 description 1
- 229910017052 cobalt Inorganic materials 0.000 description 1
- 239000010941 cobalt Substances 0.000 description 1
- GUTLYIVDDKVIGB-UHFFFAOYSA-N cobalt atom Chemical compound [Co] GUTLYIVDDKVIGB-UHFFFAOYSA-N 0.000 description 1
- 238000005056 compaction Methods 0.000 description 1
- 230000000052 comparative effect Effects 0.000 description 1
- 150000001875 compounds Chemical class 0.000 description 1
- 230000001010 compromised effect Effects 0.000 description 1
- 230000003247 decreasing effect Effects 0.000 description 1
- 238000006731 degradation reaction Methods 0.000 description 1
- 230000008021 deposition Effects 0.000 description 1
- 239000003599 detergent Substances 0.000 description 1
- 230000001627 detrimental effect Effects 0.000 description 1
- 235000014113 dietary fatty acids Nutrition 0.000 description 1
- 238000010790 dilution Methods 0.000 description 1
- 239000012895 dilution Substances 0.000 description 1
- 230000003292 diminished effect Effects 0.000 description 1
- 238000007598 dipping method Methods 0.000 description 1
- 239000006185 dispersion Substances 0.000 description 1
- 238000002224 dissection Methods 0.000 description 1
- 238000005516 engineering process Methods 0.000 description 1
- HQPMKSGTIOYHJT-UHFFFAOYSA-N ethane-1,2-diol;propane-1,2-diol Chemical compound OCCO.CC(O)CO HQPMKSGTIOYHJT-UHFFFAOYSA-N 0.000 description 1
- 238000002474 experimental method Methods 0.000 description 1
- 238000001125 extrusion Methods 0.000 description 1
- 239000000194 fatty acid Substances 0.000 description 1
- 229930195729 fatty acid Natural products 0.000 description 1
- 150000004665 fatty acids Chemical class 0.000 description 1
- 230000002600 fibrillogenic effect Effects 0.000 description 1
- 239000002657 fibrous material Substances 0.000 description 1
- 238000011049 filling Methods 0.000 description 1
- 230000005251 gamma ray Effects 0.000 description 1
- 210000001035 gastrointestinal tract Anatomy 0.000 description 1
- 239000011521 glass Substances 0.000 description 1
- 239000003365 glass fiber Substances 0.000 description 1
- 239000011491 glass wool Substances 0.000 description 1
- 230000008588 hemolysis Effects 0.000 description 1
- 208000021760 high fever Diseases 0.000 description 1
- 238000007731 hot pressing Methods 0.000 description 1
- 230000002209 hydrophobic effect Effects 0.000 description 1
- 125000002887 hydroxy group Chemical group [H]O* 0.000 description 1
- 230000006698 induction Effects 0.000 description 1
- 239000012678 infectious agent Substances 0.000 description 1
- 206010022000 influenza Diseases 0.000 description 1
- 238000001802 infusion Methods 0.000 description 1
- 230000002401 inhibitory effect Effects 0.000 description 1
- 238000002347 injection Methods 0.000 description 1
- 239000007924 injection Substances 0.000 description 1
- 238000001746 injection moulding Methods 0.000 description 1
- 238000007689 inspection Methods 0.000 description 1
- 238000011835 investigation Methods 0.000 description 1
- JEIPFZHSYJVQDO-UHFFFAOYSA-N iron(III) oxide Inorganic materials O=[Fe]O[Fe]=O JEIPFZHSYJVQDO-UHFFFAOYSA-N 0.000 description 1
- 230000002427 irreversible effect Effects 0.000 description 1
- 235000015110 jellies Nutrition 0.000 description 1
- 239000008274 jelly Substances 0.000 description 1
- 210000002429 large intestine Anatomy 0.000 description 1
- 239000006194 liquid suspension Substances 0.000 description 1
- 210000002652 macrocyte Anatomy 0.000 description 1
- 238000012423 maintenance Methods 0.000 description 1
- 230000036210 malignancy Effects 0.000 description 1
- 230000001404 mediated effect Effects 0.000 description 1
- 239000000155 melt Substances 0.000 description 1
- 239000012528 membrane Substances 0.000 description 1
- 238000012544 monitoring process Methods 0.000 description 1
- 210000003205 muscle Anatomy 0.000 description 1
- 125000004123 n-propyl group Chemical group [H]C([H])([H])C([H])([H])C([H])([H])* 0.000 description 1
- 201000009240 nasopharyngitis Diseases 0.000 description 1
- 230000000926 neurological effect Effects 0.000 description 1
- 239000002736 nonionic surfactant Substances 0.000 description 1
- 239000004745 nonwoven fabric Substances 0.000 description 1
- 102000039446 nucleic acids Human genes 0.000 description 1
- 108020004707 nucleic acids Proteins 0.000 description 1
- 150000007523 nucleic acids Chemical class 0.000 description 1
- 210000000056 organ Anatomy 0.000 description 1
- 150000002924 oxiranes Chemical class 0.000 description 1
- 238000004806 packaging method and process Methods 0.000 description 1
- 238000012856 packing Methods 0.000 description 1
- 230000036961 partial effect Effects 0.000 description 1
- 230000002093 peripheral effect Effects 0.000 description 1
- 230000000704 physical effect Effects 0.000 description 1
- 239000002504 physiological saline solution Substances 0.000 description 1
- 229920001993 poloxamer 188 Polymers 0.000 description 1
- 229920003229 poly(methyl methacrylate) Polymers 0.000 description 1
- 229920002239 polyacrylonitrile Polymers 0.000 description 1
- 229920005668 polycarbonate resin Polymers 0.000 description 1
- 239000004431 polycarbonate resin Substances 0.000 description 1
- 229920000573 polyethylene Polymers 0.000 description 1
- 229920000306 polymethylpentene Polymers 0.000 description 1
- 235000010482 polyoxyethylene sorbitan monooleate Nutrition 0.000 description 1
- 229920000053 polysorbate 80 Polymers 0.000 description 1
- 229920002981 polyvinylidene fluoride Polymers 0.000 description 1
- 239000003755 preservative agent Substances 0.000 description 1
- 238000004080 punching Methods 0.000 description 1
- 239000000376 reactant Substances 0.000 description 1
- 238000012552 review Methods 0.000 description 1
- 229920006395 saturated elastomer Polymers 0.000 description 1
- 238000004062 sedimentation Methods 0.000 description 1
- 239000004317 sodium nitrate Substances 0.000 description 1
- 235000010344 sodium nitrate Nutrition 0.000 description 1
- 239000002195 soluble material Substances 0.000 description 1
- 239000012798 spherical particle Substances 0.000 description 1
- 230000002269 spontaneous effect Effects 0.000 description 1
- 229910001220 stainless steel Inorganic materials 0.000 description 1
- 239000010935 stainless steel Substances 0.000 description 1
- 230000001954 sterilising effect Effects 0.000 description 1
- 238000004659 sterilization and disinfection Methods 0.000 description 1
- 238000001356 surgical procedure Methods 0.000 description 1
- 230000004083 survival effect Effects 0.000 description 1
- 230000008961 swelling Effects 0.000 description 1
- ISXSCDLOGDJUNJ-UHFFFAOYSA-N tert-butyl prop-2-enoate Chemical compound CC(C)(C)OC(=O)C=C ISXSCDLOGDJUNJ-UHFFFAOYSA-N 0.000 description 1
- 238000002560 therapeutic procedure Methods 0.000 description 1
- 239000012815 thermoplastic material Substances 0.000 description 1
- 230000009385 viral infection Effects 0.000 description 1
- 238000003466 welding Methods 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
- A61M1/36—Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits
- A61M1/3621—Extra-corporeal blood circuits
- A61M1/3627—Degassing devices; Buffer reservoirs; Drip chambers; Blood filters
- A61M1/3633—Blood component filters, e.g. leukocyte filters
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D35/00—Filtering devices having features not specifically covered by groups B01D24/00 - B01D33/00, or for applications not specifically covered by groups B01D24/00 - B01D33/00; Auxiliary devices for filtration; Filter housing constructions
- B01D35/30—Filter housing constructions
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D39/00—Filtering material for liquid or gaseous fluids
- B01D39/02—Loose filtering material, e.g. loose fibres
- B01D39/04—Organic material, e.g. cellulose, cotton
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D39/00—Filtering material for liquid or gaseous fluids
- B01D39/14—Other self-supporting filtering material ; Other filtering material
- B01D39/16—Other self-supporting filtering material ; Other filtering material of organic material, e.g. synthetic fibres
- B01D39/1607—Other self-supporting filtering material ; Other filtering material of organic material, e.g. synthetic fibres the material being fibrous
- B01D39/1623—Other self-supporting filtering material ; Other filtering material of organic material, e.g. synthetic fibres the material being fibrous of synthetic origin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M2202/00—Special media to be introduced, removed or treated
- A61M2202/04—Liquids
- A61M2202/0413—Blood
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M2202/00—Special media to be introduced, removed or treated
- A61M2202/04—Liquids
- A61M2202/0413—Blood
- A61M2202/0439—White blood cells; Leucocytes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M2205/00—General characteristics of the apparatus
- A61M2205/75—General characteristics of the apparatus with filters
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D2239/00—Aspects relating to filtering material for liquid or gaseous fluids
- B01D2239/12—Special parameters characterising the filtering material
- B01D2239/1208—Porosity
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D2239/00—Aspects relating to filtering material for liquid or gaseous fluids
- B01D2239/12—Special parameters characterising the filtering material
- B01D2239/1216—Pore size
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D2239/00—Aspects relating to filtering material for liquid or gaseous fluids
- B01D2239/12—Special parameters characterising the filtering material
- B01D2239/1291—Other parameters
Landscapes
- Health & Medical Sciences (AREA)
- Heart & Thoracic Surgery (AREA)
- Vascular Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Anesthesiology (AREA)
- Biomedical Technology (AREA)
- Hematology (AREA)
- Cardiology (AREA)
- Animal Behavior & Ethology (AREA)
- Engineering & Computer Science (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- External Artificial Organs (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Separation Using Semi-Permeable Membranes (AREA)
- Filtering Materials (AREA)
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US11041387A | 1987-10-20 | 1987-10-20 | |
| US110413 | 1987-10-20 | ||
| US21816988A | 1988-07-13 | 1988-07-13 | |
| US218169 | 1988-07-13 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| ES2183827T3 ES2183827T3 (es) | 2003-04-01 |
| ES2183827T5 true ES2183827T5 (es) | 2008-04-16 |
Family
ID=26808000
Family Applications (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES94201693T Expired - Lifetime ES2183827T5 (es) | 1987-10-20 | 1988-10-20 | Dispositivo y metodo para el agotamiento del contenido en leucocitos de productos de sangre. |
| ES88309851T Expired - Lifetime ES2067476T5 (es) | 1987-10-20 | 1988-10-20 | Dispositivo y metodo para agotar el contenido en leucocitos de sangre y de componentes de la sangre. |
| ES02076566T Expired - Lifetime ES2249538T3 (es) | 1987-10-20 | 1988-10-20 | Dispositivo y metodo para agotar el contenido de leucocitos de componentes de sangre. |
Family Applications After (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES88309851T Expired - Lifetime ES2067476T5 (es) | 1987-10-20 | 1988-10-20 | Dispositivo y metodo para agotar el contenido en leucocitos de sangre y de componentes de la sangre. |
| ES02076566T Expired - Lifetime ES2249538T3 (es) | 1987-10-20 | 1988-10-20 | Dispositivo y metodo para agotar el contenido de leucocitos de componentes de sangre. |
Country Status (17)
| Country | Link |
|---|---|
| EP (3) | EP0313348B2 (Direct) |
| JP (1) | JP2555722B2 (Direct) |
| KR (1) | KR950005186B1 (Direct) |
| CN (3) | CN1025653C (Direct) |
| AT (3) | ATE116864T1 (Direct) |
| AU (1) | AU642601B2 (Direct) |
| BR (1) | BR8807759A (Direct) |
| CA (1) | CA1325974C (Direct) |
| DE (4) | DE313348T1 (Direct) |
| ES (3) | ES2183827T5 (Direct) |
| GB (1) | GB2211755B (Direct) |
| GR (1) | GR3015682T3 (Direct) |
| IL (1) | IL88081A0 (Direct) |
| IN (1) | IN172156B (Direct) |
| NO (1) | NO994959D0 (Direct) |
| NZ (1) | NZ226628A (Direct) |
| WO (1) | WO1989003717A1 (Direct) |
Families Citing this family (57)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5019260A (en) * | 1986-12-23 | 1991-05-28 | Pall Corporation | Filtration media with low protein adsorbability |
| US4959150A (en) * | 1988-09-26 | 1990-09-25 | Pall Corporation | Fluid treatment system having low affinity for proteinaceous materials |
| DE69005354D1 (de) * | 1989-05-09 | 1994-02-03 | Pall Corp | Vorrichtung und Verfahren zur Verminderung des Leukocytengehalts von Blut und Blutkomponenten. |
| EP0406485A1 (en) * | 1989-07-03 | 1991-01-09 | NPBI Nederlands Produktielaboratorium voor Bloedtransfusieapparatuur en Infusievloeistoffen B.V. | A method for the removal of leukocytes from a leukocyte-containing suspension and filter unit for use with the method |
| JP2523938B2 (ja) * | 1989-09-18 | 1996-08-14 | テルモ株式会社 | 血小板純化用フィルタ― |
| AU640186B2 (en) * | 1989-12-28 | 1993-08-19 | Pall Corporation | Device and method for blood separation |
| US5126054A (en) * | 1990-05-24 | 1992-06-30 | Pall Corporation | Venting means |
| GB2277886A (en) * | 1990-07-27 | 1994-11-16 | Pall Corp | Leucocyte depleting filter |
| DE69119683T2 (de) * | 1990-07-27 | 1996-10-02 | Pall Corp | Filtereinrichtung zur Entfernung von Leukozyten und Methode zur Verwendung |
| US5362406A (en) * | 1990-07-27 | 1994-11-08 | Pall Corporation | Leucocyte depleting filter device and method of use |
| GB9106481D0 (en) * | 1991-03-27 | 1991-05-15 | Pall Corp | Filters and filter units |
| US5186843A (en) * | 1991-07-22 | 1993-02-16 | Ahlstrom Filtration, Inc. | Blood separation media and method for separating plasma from whole blood |
| EP0561379B1 (en) * | 1992-03-17 | 1998-07-08 | ASAHI MEDICAL Co., Ltd. | Filter medium having a limited surface negative charge for treating a blood material |
| EP0606646B1 (en) * | 1992-12-28 | 1997-09-24 | Asahi Medical Co., Ltd. | Filtermaterial, apparatus and method for removing leukocytes |
| JP3246620B2 (ja) * | 1993-02-22 | 2002-01-15 | 旭メディカル株式会社 | 白血球除去フィルター支持体 |
| US5582907A (en) * | 1994-07-28 | 1996-12-10 | Pall Corporation | Melt-blown fibrous web |
| CA2177442A1 (en) * | 1995-05-29 | 1996-11-30 | Massimo Fini | Cardiotomy reservoir with internal filter |
| US5653888A (en) * | 1995-11-02 | 1997-08-05 | Arbor Technologies, Inc. | Fluid filter assembly including gel removing barbs |
| EP0880988B1 (en) * | 1996-09-25 | 2004-07-21 | Chisso Corporation | High-precision filter |
| US5879624A (en) | 1997-01-15 | 1999-03-09 | Boehringer Laboratories, Inc. | Method and apparatus for collecting and processing blood |
| ITTO20020080A1 (it) * | 2002-01-29 | 2003-07-29 | Biofil Srl | Sistema sterile e procedimento per filtrare liquidi biologici o organici, in particolare sangue o componenti del sangue. |
| FR2835752B1 (fr) * | 2002-02-13 | 2004-11-26 | Maco Pharma Sa | Unite de filtration comprenant des couches deleucocytantes calandrees |
| ITTO20020736A1 (it) * | 2002-08-21 | 2004-02-22 | Fresenius Hemocare Italia Srl | Filtro per leucociti e suo impiego per l'impoverimento di prodotti del sangue da leucociti. |
| ITTO20030039A1 (it) * | 2003-01-24 | 2004-07-25 | Fresenius Hemocare Italia Srl | Filtro per separare leucociti da sangue intero e/o da preparati derivati dal sangue, procedimento per la fabbricazione del filtro, dispositivo e utilizzazione. |
| DE10304365A1 (de) * | 2003-02-04 | 2004-08-05 | Ls-Medcap Gmbh | Filtervorrichtung |
| EP1493458B1 (en) | 2003-07-03 | 2007-01-17 | Fresenius Hemocare Italia S.r.l. | A filter for the removal of substances from blood products |
| US7534348B2 (en) * | 2003-09-12 | 2009-05-19 | Fenwal, Inc. | Flow-through removal device and system using such device |
| DE60307849T2 (de) | 2003-09-23 | 2007-01-04 | Fresenius Hemocare Italia S.R.L., Cavezzo | Filter, Reinigungsvorrichtung und Verfahren zum Entfernen von Substanzen aus Blutprodukten |
| US7424821B1 (en) | 2004-06-25 | 2008-09-16 | Baxter International Inc. | Characterization of porous media |
| CN100556501C (zh) | 2004-12-10 | 2009-11-04 | 弗雷森纽斯血液护理意大利有限公司 | 一种多孔渗透网，特别适于过滤生物液体 |
| FR2925352B1 (fr) | 2007-12-21 | 2010-02-26 | Maco Pharma Sa | Procede de greffage d'un element poreux pour la deleucocytation |
| BRPI0911314A2 (pt) | 2008-04-14 | 2015-09-29 | Asahi Kasei Medical Co Ltd | material filtrante para remoção de agregados, e, método de filtrar um produto de sangue. |
| US9649424B2 (en) * | 2009-06-30 | 2017-05-16 | Kaneka Corporation | Blood component separation system and separation material |
| DE102009051945A1 (de) | 2009-11-04 | 2011-05-05 | Fresenius Medical Care Deutschland Gmbh | Medikamentenapplikationsadapter mit Gassperrelement für ein Hämodialyseschlauchset |
| CN102821796B (zh) * | 2010-03-31 | 2015-11-25 | 旭化成医疗株式会社 | 白血球去除器的启动加注系统以及启动加注方法 |
| WO2011125618A1 (ja) | 2010-03-31 | 2011-10-13 | 旭化成クラレメディカル株式会社 | リガンド固定化用基材及びその製造方法 |
| RU2429897C1 (ru) * | 2010-04-02 | 2011-09-27 | Евгений Иванович ВЕРХОЛОМОВ | Фильтрующий элемент для тонкой очистки сырого молока |
| US8337701B2 (en) * | 2011-03-14 | 2012-12-25 | Pall Corporation | Intravenous filter |
| US10073012B2 (en) | 2011-09-04 | 2018-09-11 | Agilent Technologies, Inc. | Debris filter for fluidic measurement with recess size decreasing in fluid flow direction |
| US9421317B2 (en) | 2012-06-08 | 2016-08-23 | Pall Corporation | Cell harvesting device and system |
| US9427512B2 (en) * | 2012-06-08 | 2016-08-30 | Pall Corporation | Filter device |
| JP5922777B2 (ja) | 2012-07-25 | 2016-05-24 | 旭化成メディカル株式会社 | 血液処理フィルター、血液回路、及び血液処理方法 |
| US11090590B2 (en) | 2012-11-13 | 2021-08-17 | Hollingsworth & Vose Company | Pre-coalescing multi-layered filter media |
| US9149749B2 (en) | 2012-11-13 | 2015-10-06 | Hollingsworth & Vose Company | Pre-coalescing multi-layered filter media |
| US9523132B2 (en) | 2013-03-15 | 2016-12-20 | Ut-Battelle, Llc | Rapid and highly fieldable viral diagnostic |
| BR112015023846A2 (pt) | 2013-03-18 | 2017-07-18 | Asahi Kasei Medical Co Ltd | material de filtro de remoção de agregados para remover um agregado em um produto sangíneo, método de remoção de agregados, filtro de remoção de glóbulos brancos, e, método de filtração de produto sanguíneo |
| FR3003764B1 (fr) | 2013-03-27 | 2015-05-01 | Maco Pharma Sa | Unite de filtration des leucocytes a adhesion des plaquettes reduite |
| ITTO20131037A1 (it) | 2013-12-18 | 2015-06-19 | Fond Istituto Italiano Di Tecnologia | Procedimento per l'incapsulazione di un liquido |
| US10399024B2 (en) | 2014-05-15 | 2019-09-03 | Hollingsworth & Vose Company | Surface modified filter media |
| US10828587B2 (en) * | 2015-04-17 | 2020-11-10 | Hollingsworth & Vose Company | Stable filter media including nanofibers |
| EP3417892B1 (en) * | 2016-02-15 | 2025-04-02 | Asahi Kasei Medical Co., Ltd. | Blood processing filter |
| US10625196B2 (en) | 2016-05-31 | 2020-04-21 | Hollingsworth & Vose Company | Coalescing filter media |
| US11607483B2 (en) * | 2017-03-24 | 2023-03-21 | Terumo Kabushiki Kaisha | Blood separation method and blood separation filter |
| US11452959B2 (en) | 2018-11-30 | 2022-09-27 | Hollingsworth & Vose Company | Filter media having a fine pore size distribution |
| CN109529444A (zh) * | 2018-12-17 | 2019-03-29 | 刘向晖 | 一种去除血液样本中血细胞的过滤技术及过滤器 |
| TWI715998B (zh) | 2019-01-28 | 2021-01-11 | 笙特科技股份有限公司 | 過濾材料及其製造方法 |
| US20220080107A1 (en) * | 2020-09-11 | 2022-03-17 | Carefusion 303. Inc. | Drip chamber assembly |
Family Cites Families (40)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE1928052A1 (de) * | 1969-12-05 | 1970-12-10 | Swank Dr Roy Laver | Methode und Geraet fuer Blut-Praeparation |
| US3765536A (en) † | 1970-11-10 | 1973-10-16 | Pall Corp | Blood filter cascade |
| US3802432A (en) * | 1972-05-18 | 1974-04-09 | I Djerassi | Apparatus for filtration-leukopheresis for separation and concentration of human granulocytes |
| US3935111A (en) * | 1973-04-06 | 1976-01-27 | Bentley Laboratories, Inc. | Device for removing blood microemboli |
| US3905905A (en) * | 1974-01-11 | 1975-09-16 | Ivac Corp | Filter unit |
| AR205025A1 (es) * | 1974-04-19 | 1976-03-31 | Johnson & Johnson | Medios para filtrar sangre |
| SE406039B (sv) * | 1974-08-29 | 1979-01-22 | Transcodan | I vetskestrommen fran infusions- och transfusionsapparater inkopplad filterenhet |
| US4157965A (en) * | 1975-01-20 | 1979-06-12 | Bentley Laboratories, Inc. | Blood treating device |
| US4056476A (en) * | 1975-02-27 | 1977-11-01 | Johnson & Johnson | Blood filter media |
| NO760938L (Direct) * | 1975-03-22 | 1976-09-23 | Biotest Serum Institut Gmbh | |
| US4009714A (en) * | 1975-07-30 | 1977-03-01 | Johnson & Johnson | Intravenous solution filter unit |
| IL51209A (en) * | 1976-03-25 | 1981-02-27 | Baxter Travenol Lab | Blood filter |
| JPS5359017A (en) * | 1976-11-02 | 1978-05-27 | Terumo Corp | Fractionation and purification of red blood corpuscle |
| GB2030466B (en) * | 1977-08-01 | 1982-11-10 | Pioneer Filters Inc | High capaciy blood transfusion micro filter |
| JPS5446811A (en) * | 1977-09-20 | 1979-04-13 | Asahi Chem Ind Co Ltd | Method for removing leukocytes from blood |
| JPS5854126B2 (ja) * | 1978-03-06 | 1983-12-02 | 旭化成株式会社 | 白血球分離材 |
| JPS55101267A (en) * | 1979-01-31 | 1980-08-01 | Asahi Chemical Ind | Leukocyte separator |
| JPS55129755A (en) * | 1979-03-30 | 1980-10-07 | Asahi Chem Ind Co Ltd | Catch and pick-up filter of white corpuscle |
| JPS55135750A (en) * | 1979-04-12 | 1980-10-22 | Asahi Chem Ind Co Ltd | Lymphocyte separation filter |
| JPS55136955A (en) * | 1979-04-13 | 1980-10-25 | Asahi Chem Ind Co Ltd | Filter for catching and gathering leucocyte |
| US4334901A (en) * | 1979-08-10 | 1982-06-15 | American Optical Corporation | Respirator cartridge |
| US4294594A (en) * | 1979-10-02 | 1981-10-13 | United States Surgical Corporation | Self-contained filter assembly for removing air, particles and bacteria from a solution |
| JPS603367B2 (ja) * | 1979-10-09 | 1985-01-28 | 旭化成株式会社 | 白血球分離法および白血球分離材 |
| US4294599A (en) * | 1980-02-19 | 1981-10-13 | American Optical Corporation | Aerosol filter cartridge |
| GB2077137B (en) * | 1980-03-12 | 1983-09-07 | Asahi Chemical Ind | Granulocyte-separating material and granulocyte separator |
| JPS57145662A (en) * | 1981-03-02 | 1982-09-08 | Asahi Chemical Ind | Filter, method and apparatus for sampling white corpuscle component |
| JPS57145663A (en) * | 1981-03-05 | 1982-09-08 | Asahi Chemical Ind | Apparatus and method for catching and sampling lymph |
| US4432875A (en) * | 1981-05-29 | 1984-02-21 | Brunswick Corporation | Semi-permeable membranes and processes for making the same |
| US4540492A (en) * | 1981-11-16 | 1985-09-10 | Millipore Corporation | Method and apparatus for treating whole blood |
| US4617124A (en) * | 1982-07-13 | 1986-10-14 | Pall Corporation | Polymeric microfibrous filter sheet, preparation and use |
| JPS60203267A (ja) * | 1984-03-27 | 1985-10-14 | 旭メデイカル株式会社 | 白血球除去用フイルタ−装置 |
| EP0155003B1 (en) * | 1984-03-15 | 1990-07-04 | ASAHI MEDICAL Co., Ltd. | Filtering unit for removing leukocytes |
| US4694685A (en) * | 1984-06-11 | 1987-09-22 | Marbetech Corporation | Apparatus and methods for determining the wettability of various substrates |
| DD228172A1 (de) * | 1984-10-16 | 1985-10-09 | Medizin Labortechnik Veb K | Blutbehaelter |
| JPS61106640A (ja) * | 1984-10-30 | 1986-05-24 | Toa Nenryo Kogyo Kk | 親水性ポリエチレン微多孔膜 |
| US4676807A (en) * | 1985-07-05 | 1987-06-30 | Pall Corporation | Process for removal of liquid aerosols from gaseous streams |
| WO1987005812A1 (fr) † | 1986-03-28 | 1987-10-08 | Asahi Medical Co., Ltd. | Filtre pour l'extraction selective de leucocytes |
| US4774132A (en) * | 1986-05-01 | 1988-09-27 | Pall Corporation | Polyvinylidene difluoride structure |
| JPS62262705A (ja) * | 1986-05-07 | 1987-11-14 | Agency Of Ind Science & Technol | 親水性多孔質膜、その製造方法およびこの親水性多孔質膜を用いた血漿分離装置 |
| JPH0614968B2 (ja) * | 1987-06-15 | 1994-03-02 | テルモ株式会社 | 白血球捕捉分離器具 |
-
1988
- 1988-10-18 IL IL88081A patent/IL88081A0/xx not_active IP Right Cessation
- 1988-10-19 WO PCT/US1988/003598 patent/WO1989003717A1/en not_active Ceased
- 1988-10-19 KR KR1019890701105A patent/KR950005186B1/ko not_active Expired - Lifetime
- 1988-10-19 BR BR888807759A patent/BR8807759A/pt not_active IP Right Cessation
- 1988-10-19 CA CA000580623A patent/CA1325974C/en not_active Expired - Lifetime
- 1988-10-19 NZ NZ226628A patent/NZ226628A/en unknown
- 1988-10-19 JP JP63509002A patent/JP2555722B2/ja not_active Expired - Lifetime
- 1988-10-20 AT AT88309851T patent/ATE116864T1/de not_active IP Right Cessation
- 1988-10-20 DE DE198888309851T patent/DE313348T1/de active Pending
- 1988-10-20 DE DE3852746T patent/DE3852746T3/de not_active Expired - Lifetime
- 1988-10-20 GB GB8824581A patent/GB2211755B/en not_active Expired - Lifetime
- 1988-10-20 ES ES94201693T patent/ES2183827T5/es not_active Expired - Lifetime
- 1988-10-20 AT AT94201693T patent/ATE224744T1/de not_active IP Right Cessation
- 1988-10-20 ES ES88309851T patent/ES2067476T5/es not_active Expired - Lifetime
- 1988-10-20 EP EP88309851A patent/EP0313348B2/en not_active Expired - Lifetime
- 1988-10-20 EP EP02076566A patent/EP1238694B1/en not_active Expired - Lifetime
- 1988-10-20 DE DE3856587T patent/DE3856587T2/de not_active Expired - Lifetime
- 1988-10-20 CN CN88108431A patent/CN1025653C/zh not_active Expired - Fee Related
- 1988-10-20 AT AT02076566T patent/ATE311932T1/de not_active IP Right Cessation
- 1988-10-20 ES ES02076566T patent/ES2249538T3/es not_active Expired - Lifetime
- 1988-10-20 DE DE3856540T patent/DE3856540T3/de not_active Expired - Lifetime
- 1988-10-20 EP EP94201693A patent/EP0620017B2/en not_active Expired - Lifetime
- 1988-10-21 IN IN733/MAS/88A patent/IN172156B/en unknown
-
1992
- 1992-07-20 AU AU20420/92A patent/AU642601B2/en not_active Expired
-
1993
- 1993-12-01 CN CN93120563A patent/CN1095308A/zh active Pending
- 1993-12-17 CN CN93121090A patent/CN1098945A/zh active Pending
-
1995
- 1995-04-04 GR GR950400829T patent/GR3015682T3/el unknown
-
1999
- 1999-10-12 NO NO994959A patent/NO994959D0/no unknown
Also Published As
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| ES2183827T5 (es) | Dispositivo y metodo para el agotamiento del contenido en leucocitos de productos de sangre. | |
| US4925572A (en) | Device and method for depletion of the leukocyte content of blood and blood components | |
| US4923620A (en) | Device for depletion of the leukocyte content of blood and blood components | |
| US4976861A (en) | Method for determining the wetting characteristic of a porous medium | |
| CN100512891C (zh) | 用于去除白细胞的方法、白细胞除去过滤器及其使用 | |
| JP2541340B2 (ja) | 血液および血液成分の白血球含量を低下させる装置および方法 | |
| JP6341934B2 (ja) | 白血球除去フィルター材、及び白血球を除去する方法 | |
| US5540841A (en) | Cardioplegia filter and method for processing cardioplegia fluid | |
| NL8802888A (nl) | Filter en werkwijze voor het vervaardigen van een leucocytenarme trombocytensuspensie. | |
| JPH04240456A (ja) | 白血球除去用フィルター装置 | |
| ES2845176T3 (es) | Elemento de filtro para filtro de tratamiento de sangre, filtro de tratamiento de sangre y método de retirada de leucocitos | |
| EP0604590A4 (en) | Gas plasma treated porous medium and method of separation using same. | |
| JPH01249063A (ja) | 血小板濃縮液から白血球を分離する装置および方法 | |
| JP2918595B2 (ja) | 白血球分離器 | |
| JP2007050013A (ja) | 白血球除去方法および白血球除去フィルター | |
| AU624095B2 (en) | Depletion of leukocyte from blood | |
| GB2250690A (en) | Blood filters | |
| IL106893A (en) | Method and device for separating material (sea) from a liquid intended for insertion into a patient | |
| JP2555722C (Direct) | ||
| JPH0640898B2 (ja) | 輸血セット |