ES2178169T3 - Compuestos para la inhibicion de la secrecion de acido gastrico. - Google Patents

Compuestos para la inhibicion de la secrecion de acido gastrico.

Info

Publication number
ES2178169T3
ES2178169T3 ES98907306T ES98907306T ES2178169T3 ES 2178169 T3 ES2178169 T3 ES 2178169T3 ES 98907306 T ES98907306 T ES 98907306T ES 98907306 T ES98907306 T ES 98907306T ES 2178169 T3 ES2178169 T3 ES 2178169T3
Authority
ES
Spain
Prior art keywords
gastric acid
inhibition
compounds
acid secretion
secretion
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES98907306T
Other languages
English (en)
Inventor
Kosrat Amin
Mikael Dahlstrom
Peter Nordberg
Ingemar Starke
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
AstraZeneca AB
Original Assignee
AstraZeneca AB
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by AstraZeneca AB filed Critical AstraZeneca AB
Application granted granted Critical
Publication of ES2178169T3 publication Critical patent/ES2178169T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

La presente invención se refiere a derivados de imidazo piridina de fórmula (I) en la que el resto fenilo se sustituye con un alquilo inferior en las posiciones 2 y 6, lo cual inhibe la secreción de ácido gástrico estimulada de manera exógena o endógena y por lo tanto se pueden utilizar en la prevención y tratamiento de enfermedades inflamatorias gastrointestinales.
ES98907306T 1997-02-25 1998-02-17 Compuestos para la inhibicion de la secrecion de acido gastrico. Expired - Lifetime ES2178169T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
SE9700661A SE9700661D0 (sv) 1997-02-25 1997-02-25 New compounds

Publications (1)

Publication Number Publication Date
ES2178169T3 true ES2178169T3 (es) 2002-12-16

Family

ID=20405920

Family Applications (1)

Application Number Title Priority Date Filing Date
ES98907306T Expired - Lifetime ES2178169T3 (es) 1997-02-25 1998-02-17 Compuestos para la inhibicion de la secrecion de acido gastrico.

Country Status (33)

Country Link
US (1) US6265415B1 (es)
EP (1) EP0971920B1 (es)
JP (1) JP2001512477A (es)
KR (1) KR20000075622A (es)
CN (1) CN1100056C (es)
AR (1) AR011134A1 (es)
AT (1) ATE218569T1 (es)
AU (1) AU723389B2 (es)
BR (1) BR9807457A (es)
CA (1) CA2280008A1 (es)
CZ (1) CZ291681B6 (es)
DE (1) DE69805787T2 (es)
DK (1) DK0971920T3 (es)
EE (1) EE04016B1 (es)
ES (1) ES2178169T3 (es)
HK (1) HK1024248A1 (es)
HU (1) HUP0000720A3 (es)
ID (1) ID22218A (es)
IL (1) IL131122A0 (es)
IS (1) IS1901B (es)
MY (1) MY118822A (es)
NO (1) NO313009B1 (es)
NZ (1) NZ336878A (es)
PL (1) PL190379B1 (es)
PT (1) PT971920E (es)
RU (1) RU2193036C2 (es)
SE (1) SE9700661D0 (es)
SK (1) SK283903B6 (es)
TR (1) TR199902060T2 (es)
TW (1) TW568907B (es)
UA (1) UA64741C2 (es)
WO (1) WO1998037080A1 (es)
ZA (1) ZA981134B (es)

Families Citing this family (28)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7141244B1 (en) * 1992-03-02 2006-11-28 Chiron Srl Helicobacter pylori proteins useful for vaccines and diagnostics
AU695769B2 (en) * 1994-07-01 1998-08-20 Provost Fellows And Scholars Of The College Of The Holy And Undivided Trinity Of Queen Elizabeth Near Dublin, The Helicobacter proteins and vaccines
WO1997025429A1 (en) * 1996-01-04 1997-07-17 Rican Limited Helicobacter pylori bacterioferritin
SE9602286D0 (sv) 1996-06-10 1996-06-10 Astra Ab New compounds
SE9704404D0 (sv) 1997-11-28 1997-11-28 Astra Ab New compounds
SE9802794D0 (sv) * 1998-08-21 1998-08-21 Astra Ab New compounds
DE10001037C1 (de) 2000-01-13 2001-12-13 Byk Gulden Lomberg Chem Fab Verfahren und Zwischenprodukte zur Herstellung von Imidazopyridinen
UA80393C2 (uk) 2000-12-07 2007-09-25 Алтана Фарма Аг Фармацевтична композиція, яка містить інгібітор фде 4, диспергований в матриці
CA2458854A1 (en) * 2001-08-31 2003-03-06 Chiron Srl Helicobacter pylori vaccination
DE10145457A1 (de) 2001-09-14 2003-04-03 Basf Ag Substituierte Imidazo[1,2-a]-5,6,7,8-tetrahydropyridin-8-one, Verfahren zu ihrer Herstellung, sowie deren Verwendung zur Herstellung von Imidazo[1,2,-a]pyridinen
MY140561A (en) 2002-02-20 2009-12-31 Nycomed Gmbh Dosage form containing pde 4 inhibitor as active ingredient
MXPA05003058A (es) 2002-09-19 2005-05-27 Schering Corp Nuevas imidazopiridinas como inhibidores de cinasa dependientes de ciclina.
CN103265477B (zh) * 2003-02-26 2017-01-11 苏根公司 作为蛋白激酶抑制剂的氨基杂芳基化合物
EA009985B1 (ru) 2003-03-10 2008-04-28 Никомед Гмбх Новый способ получения рофлумиласта
EP1670795A1 (en) * 2003-09-18 2006-06-21 ALTANA Pharma AG Pharmacologically active imidazo 4,5-c pyridines
EP1974730A1 (en) 2003-11-03 2008-10-01 AstraZeneca AB Imidazo[1,2-a]pyridine derivatives for use in the treatment of sleep disturbance due to silent gastro-esophageal reflux
ATE527258T1 (de) * 2004-07-28 2011-10-15 Takeda Pharmaceutical Pyrroloä2,3-cüpyridinverbindung, verfahren zu deren herstellung und anwendung
PT1784402E (pt) 2004-09-03 2011-08-23 Yuhan Corp Derivados de pirrolo[3,2-c]piridina e processos para a sua preparação
BRPI0514695A (pt) 2004-09-03 2008-06-17 Yuhan Corp derivados de pirrol[3, 2-b]piridina e processos para a preparação destes
BRPI0514925A (pt) 2004-09-03 2008-07-01 Yuhan Corp derivados de pirrol[2,3-c]piridina e processos para a preparação destes
KR101068355B1 (ko) * 2005-03-09 2011-09-28 주식회사유한양행 신규의 이미다조[1,2-ａ]피리딘 유도체 및 그의 제조방법
EP1861074B1 (en) * 2005-03-16 2013-04-24 Takeda GmbH Taste masked dosage form containing roflumilast
WO2006100119A1 (en) * 2005-03-24 2006-09-28 Glaxo Group Limited Derivatives of imidazo (1,2-a) pyridine useful as medicaments for treating gastrointestinal diseases
PL1959955T3 (pl) 2005-12-05 2011-04-29 Pfizer Prod Inc Sposób traktowania nieprawidłowego wzrostu komórek
PT1963302E (pt) 2005-12-05 2013-04-09 Pfizer Prod Inc Polimorfos de um inibidor de c-met/hgfr
US9309238B2 (en) * 2009-11-05 2016-04-12 University Of Notre Dame Du Lac Imidazo [1,2-a]pyridine compounds, synthesis thereof, and methods of using same
CA2836202A1 (en) 2011-05-30 2012-12-06 Astellas Pharma Inc. Imidazopyridine compounds
TW201439090A (zh) 2012-11-30 2014-10-16 Astellas Pharma Inc 咪唑並吡啶化合物

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ZA81219B (en) 1980-01-23 1982-01-27 Schering Corp Imidazo (1,2-a) pyridines ,process for their preparation and pharmaceutical compositions containing them
US4725601A (en) * 1985-06-04 1988-02-16 Fujisawa Pharmaceutical Co., Ltd. Certain imidazo[1,2-a]pyridines useful in the treatment of ulcers
EP0228006A1 (en) * 1985-12-16 1987-07-08 Fujisawa Pharmaceutical Co., Ltd. Imidazopyridine compounds and processes for preparation thereof

Also Published As

Publication number Publication date
MX9907650A (es) 2002-12-13
PT971920E (pt) 2002-11-29
EP0971920B1 (en) 2002-06-05
DK0971920T3 (da) 2002-09-16
ID22218A (id) 1999-09-16
PL335485A1 (en) 2000-04-25
ATE218569T1 (de) 2002-06-15
SE9700661D0 (sv) 1997-02-25
HUP0000720A3 (en) 2001-01-29
CA2280008A1 (en) 1998-08-27
PL190379B1 (pl) 2005-12-30
ZA981134B (en) 1998-08-25
US6265415B1 (en) 2001-07-24
EE04016B1 (et) 2003-04-15
CN1248257A (zh) 2000-03-22
AU723389B2 (en) 2000-08-24
NO313009B1 (no) 2002-07-29
EE9900367A (et) 2000-04-17
IS5148A (is) 1999-08-05
MY118822A (en) 2005-01-31
DE69805787D1 (de) 2002-07-11
IS1901B (is) 2003-11-20
CZ291681B6 (cs) 2003-04-16
CZ301499A3 (cs) 2000-02-16
NZ336878A (en) 2001-05-25
WO1998037080A1 (en) 1998-08-27
HUP0000720A2 (hu) 2000-10-28
EP0971920A1 (en) 2000-01-19
RU2193036C2 (ru) 2002-11-20
IL131122A0 (en) 2001-01-28
TR199902060T2 (xx) 2000-02-21
SK109999A3 (en) 2000-01-18
UA64741C2 (uk) 2004-03-15
NO994078L (no) 1999-08-24
AR011134A1 (es) 2000-08-02
NO994078D0 (no) 1999-08-24
DE69805787T2 (de) 2003-01-02
TW568907B (en) 2004-01-01
HK1024248A1 (en) 2000-10-05
KR20000075622A (ko) 2000-12-26
AU6314798A (en) 1998-09-09
BR9807457A (pt) 2000-04-25
SK283903B6 (sk) 2004-04-06
JP2001512477A (ja) 2001-08-21
CN1100056C (zh) 2003-01-29

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