ES2158557T3 - Proceso para la produccion de acido azetidina-2-carboxilico enantiomericamente puro. - Google Patents

Proceso para la produccion de acido azetidina-2-carboxilico enantiomericamente puro.

Info

Publication number
ES2158557T3
ES2158557T3 ES97921046T ES97921046T ES2158557T3 ES 2158557 T3 ES2158557 T3 ES 2158557T3 ES 97921046 T ES97921046 T ES 97921046T ES 97921046 T ES97921046 T ES 97921046T ES 2158557 T3 ES2158557 T3 ES 2158557T3
Authority
ES
Spain
Prior art keywords
production
enantiomerically pure
azetidine
carboxylic
pure acid
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES97921046T
Other languages
English (en)
Inventor
Philipp Barth
Armin Pfenninger
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
AstraZeneca AB
Original Assignee
AstraZeneca AB
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by AstraZeneca AB filed Critical AstraZeneca AB
Application granted granted Critical
Publication of ES2158557T3 publication Critical patent/ES2158557T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B57/00—Separation of optically-active compounds
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D205/00—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom
    • C07D205/02—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings
    • C07D205/04—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having no double bonds between ring members or between ring members and non-ring members

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)

Abstract

LA INVENCION SE REFIERE A UN PROCESO PARA LA PRODUCCION DE AZEOH ENANTIOMERICAMENTE PURO QUE CONSISTE EN LA CRISTALIZACION SELECTIVA DE UNA SAL DE TARTRATO DE AZEOH DIASTEREOMERICAMENTE PURA A PARTIR DE UNA SOLUCION HOMOGENEA DE AZEOH, ACIDO TARTARICO OPTICAMENTE ACTIVO, UN ACIDO ORGANICO Y UN ALDEHIDO, SEGUIDO DE LA LIBERACION DEL AMINOACIDO LIBRE.
ES97921046T 1996-04-26 1997-04-22 Proceso para la produccion de acido azetidina-2-carboxilico enantiomericamente puro. Expired - Lifetime ES2158557T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
SE9601600A SE9601600D0 (sv) 1996-04-26 1996-04-26 Improved process

Publications (1)

Publication Number Publication Date
ES2158557T3 true ES2158557T3 (es) 2001-09-01

Family

ID=20402360

Family Applications (1)

Application Number Title Priority Date Filing Date
ES97921046T Expired - Lifetime ES2158557T3 (es) 1996-04-26 1997-04-22 Proceso para la produccion de acido azetidina-2-carboxilico enantiomericamente puro.

Country Status (32)

Country Link
US (1) US6143903A (es)
EP (1) EP0906255B1 (es)
JP (2) JP2000509068A (es)
KR (1) KR100447072B1 (es)
CN (1) CN1071292C (es)
AR (1) AR006639A1 (es)
AT (1) ATE200889T1 (es)
AU (1) AU713519B2 (es)
BR (1) BR9708872A (es)
CA (1) CA2253711C (es)
CZ (1) CZ339998A3 (es)
DE (1) DE69704708T2 (es)
DK (1) DK0906255T3 (es)
EE (1) EE9800365A (es)
EG (1) EG20975A (es)
ES (1) ES2158557T3 (es)
GR (1) GR3036303T3 (es)
HU (1) HUP9901665A3 (es)
ID (1) ID16840A (es)
IL (1) IL126717A (es)
IN (1) IN186439B (es)
IS (1) IS4860A (es)
MY (1) MY132450A (es)
NO (1) NO310404B1 (es)
NZ (1) NZ332155A (es)
PL (1) PL329685A1 (es)
PT (1) PT906255E (es)
SE (1) SE9601600D0 (es)
SK (1) SK140898A3 (es)
TR (1) TR199802146T2 (es)
WO (1) WO1997041084A1 (es)
ZA (1) ZA973156B (es)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1308519B1 (en) * 1997-01-24 2006-04-19 Sumitomo Chemical Company, Limited Process for improving optical purity of azetidine-2-carboxylic acid
SE9802939D0 (sv) 1998-09-01 1998-09-01 Astra Ab New process
SE9901712D0 (sv) 1999-05-11 1999-05-11 Astra Ab New process
WO2005103005A1 (ja) * 2004-04-26 2005-11-03 Astellas Pharma Inc. β－ピリジルアラニンの光学活性体の選択的製造方法
EP2334620B1 (en) * 2008-09-05 2018-09-05 Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V. Process for enantioseparation of chiral systems with compound formation using two subsequent crystallization steps
JP2013241338A (ja) * 2010-09-09 2013-12-05 Mitsubishi Gas Chemical Co Inc 光学活性２−アミノ酪酸の製造方法
JP2013241339A (ja) * 2010-09-09 2013-12-05 Mitsubishi Gas Chemical Co Inc 光学活性アミノ酸の製造方法
CN103204783B (zh) * 2013-04-18 2015-09-02 张家港市华昌药业有限公司 一种d-赖氨酸盐酸盐的制备方法
WO2016021711A1 (ja) * 2014-08-07 2016-02-11 株式会社エーピーアイ コーポレーション アミノ酸誘導体の製造方法

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BE795874A (fr) * 1972-02-25 1973-08-23 Glaxo Lab Ltd Procede de preparation d'esters optiquement actifs d'alpha-amino-acides
JPS5139219B2 (es) * 1972-06-08 1976-10-26
US4072698A (en) * 1976-12-02 1978-02-07 The Upjohn Company Resolution of aminonitriles
JPS56104866A (en) * 1980-01-24 1981-08-20 Mitsubishi Chem Ind Ltd Production of (2r,4r)-4-alkyl-2-piperidinecarboxylic acid or its l-tartarate salt
DE3303112A1 (de) * 1983-01-31 1984-08-09 Hoechst Ag, 6230 Frankfurt Verfahren zur racemattrennung optisch aktiver bicyclischer imino-(alpha)-carbonsaeuren
US4923983A (en) * 1989-07-31 1990-05-08 Eli Lilly And Company Method of resolving cis 3-amino-4-[2-(2-furyl)eth-1-yl]-1-methoxycarbonylmethyl-azetidin-2-one
EP0499376A1 (en) * 1991-01-31 1992-08-19 Hoechst Celanese Corporation Precipitation-induced asymmetric transformation of chiral alpha-amino acids and salts thereof
GB9420246D0 (en) * 1994-10-07 1994-11-23 Chiroscience Ltd Asymmetric crystallisation
IN187238B (es) * 1995-06-30 2002-03-09 Astra Ab
DE69722538T2 (de) * 1996-09-06 2004-04-29 Sumitomo Chemical Co., Ltd. Verfahren zur Herstellung von optisch aktiver Azetidin-2-Carbonsäure

Also Published As

Publication number Publication date
MY132450A (en) 2007-10-31
WO1997041084A1 (en) 1997-11-06
IN186439B (es) 2001-09-01
ID16840A (id) 1997-11-13
EP0906255A1 (en) 1999-04-07
EG20975A (en) 2000-08-30
CZ339998A3 (cs) 1999-03-17
KR100447072B1 (ko) 2004-10-14
KR20000065019A (ko) 2000-11-06
IS4860A (is) 1998-10-06
BR9708872A (pt) 1999-08-03
DE69704708T2 (de) 2001-12-06
SK140898A3 (en) 1999-05-07
AU2719497A (en) 1997-11-19
IL126717A (en) 2002-11-10
NO984681D0 (no) 1998-10-07
DE69704708D1 (de) 2001-06-07
NZ332155A (en) 2000-07-28
TR199802146T2 (xx) 1999-01-18
NO984681L (no) 1998-10-07
PT906255E (pt) 2001-10-30
HUP9901665A3 (en) 1999-11-29
JP2009120611A (ja) 2009-06-04
AR006639A1 (es) 1999-09-08
DK0906255T3 (da) 2001-08-13
EP0906255B1 (en) 2001-05-02
PL329685A1 (en) 1999-04-12
NO310404B1 (no) 2001-07-02
SE9601600D0 (sv) 1996-04-26
CN1216972A (zh) 1999-05-19
ZA973156B (en) 1997-11-06
AU713519B2 (en) 1999-12-02
US6143903A (en) 2000-11-07
EE9800365A (et) 1999-04-15
CN1071292C (zh) 2001-09-19
GR3036303T3 (en) 2001-10-31
ATE200889T1 (de) 2001-05-15
IL126717A0 (en) 1999-08-17
CA2253711C (en) 2005-08-23
HUP9901665A2 (hu) 1999-09-28
JP2000509068A (ja) 2000-07-18
CA2253711A1 (en) 1997-11-06

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