ES2152564T3 - Procedimientos e intermedios para preparar 3-(1-piperazinil)-1,2-benzoisotiazol. - Google Patents

Procedimientos e intermedios para preparar 3-(1-piperazinil)-1,2-benzoisotiazol.

Info

Publication number
ES2152564T3
ES2152564T3 ES96931940T ES96931940T ES2152564T3 ES 2152564 T3 ES2152564 T3 ES 2152564T3 ES 96931940 T ES96931940 T ES 96931940T ES 96931940 T ES96931940 T ES 96931940T ES 2152564 T3 ES2152564 T3 ES 2152564T3
Authority
ES
Spain
Prior art keywords
piperazinil
procedures
benzoisotiazol
intermediates
prepare
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES96931940T
Other languages
English (en)
Inventor
Darrell E Fox
John F Lambert
Terry G Sinay Jr
Stanley W Walinsky
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Pfizer Inc
Original Assignee
Pfizer Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer Inc filed Critical Pfizer Inc
Application granted granted Critical
Publication of ES2152564T3 publication Critical patent/ES2152564T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D275/00—Heterocyclic compounds containing 1,2-thiazole or hydrogenated 1,2-thiazole rings
    • C07D275/04—Heterocyclic compounds containing 1,2-thiazole or hydrogenated 1,2-thiazole rings condensed with carbocyclic rings or ring systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00—Drugs for disorders of the muscular or neuromuscular system
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/22—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with hetero atoms directly attached to ring nitrogen atoms
    • C07D295/26—Sulfur atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Neurology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Thiazole And Isothizaole Compounds (AREA)

Abstract

LA PRESENTE INVENCION TRATA DE PROCEDIMIENTOS PARA LA PREPARACION DE 3 - (1 - PIPERAZINIL) - 1,2 - BENCISOTIAZOL O SU SAL FARMACEUTICAMENTE ACEPTABLE Y DE NUEVOS COMPUESTOS INTERMEDIOS UTILIZADOS EN EL PROCEDIMIENTO. LOS 3 - (1 PIPERAZINIL) 1,2 - BENCISOTIAZOLES SON COMPUESTOS INTERMEDIOS CLAVE UTILES PARA LA PREPARACION DE ZIPRASIDONA.
ES96931940T 1995-11-07 1996-10-11 Procedimientos e intermedios para preparar 3-(1-piperazinil)-1,2-benzoisotiazol. Expired - Lifetime ES2152564T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US630195P 1995-11-07 1995-11-07

Publications (1)

Publication Number Publication Date
ES2152564T3 true ES2152564T3 (es) 2001-02-01

Family

ID=21720240

Family Applications (1)

Application Number Title Priority Date Filing Date
ES96931940T Expired - Lifetime ES2152564T3 (es) 1995-11-07 1996-10-11 Procedimientos e intermedios para preparar 3-(1-piperazinil)-1,2-benzoisotiazol.

Country Status (29)

Country Link
US (1) US6111105A (es)
EP (1) EP0874834B1 (es)
JP (1) JP3152938B2 (es)
KR (1) KR100315939B1 (es)
CN (1) CN1071324C (es)
AR (2) AR004279A1 (es)
AT (1) ATE198071T1 (es)
AU (1) AU698443B2 (es)
BR (1) BR9611366A (es)
CA (1) CA2236940C (es)
CO (1) CO4480028A1 (es)
CZ (1) CZ290600B6 (es)
DE (1) DE69611253T2 (es)
DK (1) DK0874834T3 (es)
ES (1) ES2152564T3 (es)
GR (1) GR3035215T3 (es)
HU (1) HU225921B1 (es)
MX (1) MX9803599A (es)
MY (1) MY116579A (es)
NO (1) NO309811B1 (es)
NZ (1) NZ318844A (es)
PE (1) PE17298A1 (es)
PL (1) PL185048B1 (es)
PT (1) PT874834E (es)
RU (1) RU2147302C1 (es)
TR (1) TR199800814T2 (es)
TW (1) TW358807B (es)
WO (1) WO1997017336A1 (es)
ZA (1) ZA969315B (es)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
UY27668A1 (es) 2002-02-20 2003-10-31 Pfizer Prod Inc Composición de ziprasidona y controles sintéticos
US20040048876A1 (en) * 2002-02-20 2004-03-11 Pfizer Inc. Ziprasidone composition and synthetic controls
EP1628973A2 (en) 2003-10-24 2006-03-01 Teva Pharmaceutical Industries Ltd. Processes for preparation of ziprasidone
US7777037B2 (en) * 2004-10-27 2010-08-17 Dr. Reddy's Laboratories Limited Ziprasidone process
CN105891392A (zh) * 2016-03-29 2016-08-24 北京万全德众医药生物技术有限公司 一种用液相色谱法分离测定盐酸鲁拉西酮中间体有关物质的方法
CN107064323A (zh) * 2016-12-05 2017-08-18 北京万全德众医药生物技术有限公司 一种用液相色谱法分离测定盐酸鲁拉西酮及其有关物质的方法

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4590196A (en) * 1984-08-23 1986-05-20 Bristol-Myers Company Analgesic 1,2-benzisothiazol-3-ylpiperazine derivatives
JPH06220030A (ja) * 1993-01-22 1994-08-09 Sumitomo Pharmaceut Co Ltd ３−アミノ−１，２−ベンズイソチアゾール誘導体の製造法
JP3701044B2 (ja) * 1995-04-24 2005-09-28 住友精化株式会社 シアノベンゼンスルフェニルハライドおよびそれを用いる３−置換ベンゾイソチアゾールの製造方法
JP3996228B2 (ja) * 1996-10-11 2007-10-24 住友精化株式会社 ３−ピペラジニルベンズイソチアゾール類の製造法

Also Published As

Publication number Publication date
NO309811B1 (no) 2001-04-02
AR004279A1 (es) 1998-11-04
MY116579A (en) 2004-02-28
HU225921B1 (en) 2008-01-28
MX9803599A (es) 1998-09-30
HUP9903765A2 (hu) 2000-03-28
CN1071324C (zh) 2001-09-19
CA2236940A1 (en) 1997-05-15
PT874834E (pt) 2001-04-30
US6111105A (en) 2000-08-29
AU698443B2 (en) 1998-10-29
HUP9903765A3 (en) 2001-12-28
KR100315939B1 (ko) 2002-01-16
CZ137898A3 (cs) 1999-03-17
NZ318844A (en) 1999-04-29
CN1201457A (zh) 1998-12-09
KR19990067381A (ko) 1999-08-16
AR032373A2 (es) 2003-11-05
DE69611253D1 (de) 2001-01-18
GR3035215T3 (en) 2001-04-30
ATE198071T1 (de) 2000-12-15
DE69611253T2 (de) 2001-04-05
JPH10512595A (ja) 1998-12-02
WO1997017336A1 (en) 1997-05-15
EP0874834B1 (en) 2000-12-13
BR9611366A (pt) 1999-02-23
ZA969315B (en) 1998-05-06
NO982051D0 (no) 1998-05-06
CA2236940C (en) 2001-08-21
PL185048B1 (pl) 2003-02-28
NO982051L (no) 1998-07-03
CZ290600B6 (cs) 2002-08-14
AU7092696A (en) 1997-05-29
PE17298A1 (es) 1998-04-16
TW358807B (en) 1999-05-21
CO4480028A1 (es) 1997-07-09
TR199800814T2 (xx) 1998-07-21
EP0874834A1 (en) 1998-11-04
PL326630A1 (en) 1998-10-12
JP3152938B2 (ja) 2001-04-03
RU2147302C1 (ru) 2000-04-10
DK0874834T3 (da) 2001-02-19

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