DE69717148D1 - 3-pyridylenantiomere und ihre verwendung als analgetika - Google Patents
3-pyridylenantiomere und ihre verwendung als analgetikaInfo
- Publication number
- DE69717148D1 DE69717148D1 DE69717148T DE69717148T DE69717148D1 DE 69717148 D1 DE69717148 D1 DE 69717148D1 DE 69717148 T DE69717148 T DE 69717148T DE 69717148 T DE69717148 T DE 69717148T DE 69717148 D1 DE69717148 D1 DE 69717148D1
- Authority
- DE
- Germany
- Prior art keywords
- antiomers
- analgetics
- pyridylene
- formula
- compounds
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
- A61K31/485—Morphinan derivatives, e.g. morphine, codeine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D205/00—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom
- C07D205/02—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings
- C07D205/04—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Biomedical Technology (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Epidemiology (AREA)
- Pain & Pain Management (AREA)
- Hospice & Palliative Care (AREA)
- Emergency Medicine (AREA)
- Cardiology (AREA)
- Vascular Medicine (AREA)
- Urology & Nephrology (AREA)
- Rheumatology (AREA)
- Psychiatry (AREA)
- Heart & Thoracic Surgery (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Pyridine Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Hydrogenated Pyridines (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US3232196P | 1996-12-10 | 1996-12-10 | |
US76327896A | 1996-12-10 | 1996-12-10 | |
PCT/US1997/022811 WO1998025920A1 (en) | 1996-12-10 | 1997-12-10 | 3-pyridyl enantiomers and their use as analgesics |
Publications (2)
Publication Number | Publication Date |
---|---|
DE69717148D1 true DE69717148D1 (de) | 2002-12-19 |
DE69717148T2 DE69717148T2 (de) | 2003-10-02 |
Family
ID=26708255
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE69717148T Expired - Lifetime DE69717148T2 (de) | 1996-12-10 | 1997-12-10 | 3-pyridylenantiomere und ihre verwendung als analgetika |
Country Status (21)
Country | Link |
---|---|
EP (1) | EP0950057B1 (de) |
JP (2) | JP4272261B2 (de) |
KR (2) | KR100422995B1 (de) |
CN (1) | CN1125064C (de) |
AT (1) | ATE227717T1 (de) |
AU (1) | AU733881B2 (de) |
BG (1) | BG64196B1 (de) |
BR (1) | BR9714677A (de) |
CA (2) | CA2698384C (de) |
DE (1) | DE69717148T2 (de) |
DK (1) | DK0950057T3 (de) |
ES (1) | ES2189003T3 (de) |
HU (1) | HUP0001110A3 (de) |
IL (1) | IL130083A0 (de) |
NO (1) | NO992705L (de) |
NZ (1) | NZ335810A (de) |
PL (1) | PL333920A1 (de) |
PT (1) | PT950057E (de) |
SK (1) | SK75999A3 (de) |
TR (1) | TR199901904T2 (de) |
WO (1) | WO1998025920A1 (de) |
Families Citing this family (26)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CA2317572A1 (en) | 1998-04-02 | 1999-10-14 | Jared Miller Wagner | Pharmaceutical compositions and methods for use |
US6054451A (en) * | 1998-04-21 | 2000-04-25 | Algos Pharmaceutical Corporation | Analgesic composition and method for alleviating pain |
US6362371B1 (en) * | 1998-06-08 | 2002-03-26 | Advanced Medicine, Inc. | β2- adrenergic receptor agonists |
US20010031771A1 (en) | 1999-05-24 | 2001-10-18 | Gary Maurice Dull | Pharmaceutical compositions and methods for use |
US6103911A (en) * | 1999-06-15 | 2000-08-15 | Abbott Laboratories | Process for reduction of (2R)-4-oxoazetidinone-2-carboxylic acid |
US7186855B2 (en) | 2001-06-11 | 2007-03-06 | Xenoport, Inc. | Prodrugs of GABA analogs, compositions and uses thereof |
US6818787B2 (en) | 2001-06-11 | 2004-11-16 | Xenoport, Inc. | Prodrugs of GABA analogs, compositions and uses thereof |
US8048917B2 (en) | 2005-04-06 | 2011-11-01 | Xenoport, Inc. | Prodrugs of GABA analogs, compositions and uses thereof |
JP2006504634A (ja) * | 2002-05-15 | 2006-02-09 | アボット・ラボラトリーズ | 神経障害性疼痛の治療 |
EP1741709A1 (de) | 2005-06-28 | 2007-01-10 | Sanofi-Aventis Deutschland GmbH | Heteroaryl substituierte Amide mit gesättigtem Linker, und deren Verwendung als Pharmaka |
WO2007065820A1 (en) | 2005-12-09 | 2007-06-14 | F. Hoffmann-La Roche Ag | Tricyclic amide derivatives useful for treating obesity |
TW200800020A (en) * | 2006-01-26 | 2008-01-01 | Basf Ag | Methods to use 3-pyridyl derivatives as pesticides |
EP2083921A2 (de) | 2006-09-04 | 2009-08-05 | Neurosearch A/S | Pharmazeutische kombinationen aus einem nikotinrezeptormodulator und einem mittel zur intensivierung kognitiver funktionen |
JP4939192B2 (ja) * | 2006-12-05 | 2012-05-23 | ユニ・チャーム株式会社 | 不織布、不織布の製造方法及び吸収性物品 |
DE102007058504A1 (de) | 2007-12-05 | 2009-07-09 | Acino Ag | Transdermales therapeutisches System mit einem Gehalt an einem Modulator für nikotinische Acetylcholinrezeptoren (nAChR) |
CA2738806A1 (en) | 2008-10-14 | 2010-04-22 | Psychogenics, Inc. | Nicotinic acetylcholine receptor ligands and the uses thereof |
US8474529B2 (en) * | 2009-04-09 | 2013-07-02 | Regency Technologies Llc | Control of concentric tubing direction |
AR075988A1 (es) * | 2009-04-09 | 2011-05-11 | Lilly Co Eli | Compuesto de piridiloxi - pirrolidina inhibidor de recaptacion de serotonina y norepinefrina, composicion farmaceutica que lo comprende y su uso para la manufactura de un medicamento util para el tratamiento de dolor cronico |
US20140128606A1 (en) | 2011-06-30 | 2014-05-08 | Toray Industries, Inc. | Antipruritic agent |
US9890137B2 (en) | 2013-03-27 | 2018-02-13 | Georgetown University | 2-halo-5-alkynyl-pyridyl nicotinic ligands |
JP7414529B2 (ja) | 2017-06-07 | 2024-01-16 | シファメド・ホールディングス・エルエルシー | 血管内流体移動デバイス、システム、および使用方法 |
US11511103B2 (en) | 2017-11-13 | 2022-11-29 | Shifamed Holdings, Llc | Intravascular fluid movement devices, systems, and methods of use |
US10722631B2 (en) | 2018-02-01 | 2020-07-28 | Shifamed Holdings, Llc | Intravascular blood pumps and methods of use and manufacture |
US11964145B2 (en) | 2019-07-12 | 2024-04-23 | Shifamed Holdings, Llc | Intravascular blood pumps and methods of manufacture and use |
WO2021016372A1 (en) | 2019-07-22 | 2021-01-28 | Shifamed Holdings, Llc | Intravascular blood pumps with struts and methods of use and manufacture |
EP4034192A4 (de) | 2019-09-25 | 2023-11-29 | Shifamed Holdings, LLC | Intravaskuläre blutpumpensysteme und verfahren zur verwendung und steuerung davon |
Family Cites Families (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB8301702D0 (en) * | 1983-01-21 | 1983-02-23 | Shell Int Research | Azetidine compounds |
US4902684A (en) * | 1988-06-20 | 1990-02-20 | E. R. Squibb & Sons, Inc. | Benzazepine and benzothiazepine derivatives |
US5068234A (en) * | 1990-02-26 | 1991-11-26 | Sterling Drug Inc. | 3-arylcarbonyl-1-(c-attached-n-heteryl)-1h-indoles |
IL107184A (en) * | 1992-10-09 | 1997-08-14 | Abbott Lab | Heterocyclic ether compounds that enhance cognitive function |
US5585388A (en) * | 1995-04-07 | 1996-12-17 | Sibia Neurosciences, Inc. | Substituted pyridines useful as modulators of acetylcholine receptors |
IL118279A (en) * | 1995-06-07 | 2006-10-05 | Abbott Lab | Compounds 3 - Pyridyloxy (or Thio) Alkyl Heterocyclic Pharmaceutical Compositions Containing Them and Their Uses for Preparing Drugs to Control Synaptic Chemical Transmission |
US5629325A (en) * | 1996-06-06 | 1997-05-13 | Abbott Laboratories | 3-pyridyloxymethyl heterocyclic ether compounds useful in controlling chemical synaptic transmission |
-
1997
- 1997-12-10 BR BR9714677-3A patent/BR9714677A/pt not_active IP Right Cessation
- 1997-12-10 KR KR10-1999-7005151A patent/KR100422995B1/ko not_active IP Right Cessation
- 1997-12-10 CA CA2698384A patent/CA2698384C/en not_active Expired - Fee Related
- 1997-12-10 DK DK97952392T patent/DK0950057T3/da active
- 1997-12-10 WO PCT/US1997/022811 patent/WO1998025920A1/en not_active Application Discontinuation
- 1997-12-10 NZ NZ335810A patent/NZ335810A/en unknown
- 1997-12-10 ES ES97952392T patent/ES2189003T3/es not_active Expired - Lifetime
- 1997-12-10 IL IL13008397A patent/IL130083A0/xx unknown
- 1997-12-10 KR KR10-2003-7008788A patent/KR100472154B1/ko not_active IP Right Cessation
- 1997-12-10 SK SK759-99A patent/SK75999A3/sk unknown
- 1997-12-10 HU HU0001110A patent/HUP0001110A3/hu unknown
- 1997-12-10 AU AU56010/98A patent/AU733881B2/en not_active Ceased
- 1997-12-10 PT PT97952392T patent/PT950057E/pt unknown
- 1997-12-10 CN CN97181628A patent/CN1125064C/zh not_active Expired - Fee Related
- 1997-12-10 DE DE69717148T patent/DE69717148T2/de not_active Expired - Lifetime
- 1997-12-10 PL PL97333920A patent/PL333920A1/xx unknown
- 1997-12-10 AT AT97952392T patent/ATE227717T1/de active
- 1997-12-10 EP EP97952392A patent/EP0950057B1/de not_active Expired - Lifetime
- 1997-12-10 CA CA2273917A patent/CA2273917C/en not_active Expired - Fee Related
- 1997-12-10 TR TR1999/01904T patent/TR199901904T2/xx unknown
- 1997-12-10 JP JP52698398A patent/JP4272261B2/ja not_active Expired - Fee Related
-
1999
- 1999-06-03 NO NO992705A patent/NO992705L/no not_active Application Discontinuation
- 1999-07-06 BG BG103556A patent/BG64196B1/bg unknown
-
2008
- 2008-12-24 JP JP2008327771A patent/JP5364872B2/ja not_active Expired - Fee Related
Also Published As
Similar Documents
Publication | Publication Date | Title |
---|---|---|
DE69717148D1 (de) | 3-pyridylenantiomere und ihre verwendung als analgetika | |
BRPI0408784A (pt) | método para usar um composto | |
NL300382I1 (nl) | Treatment of pompe's disease | |
DE59509846D1 (de) | [a]-ANNELIERTE PYRROLDERIVATE UND DEREN ANWENDUNG IN DER PHARMAZIE | |
SE9604786D0 (sv) | New compounds | |
ATE433959T1 (de) | Analoge von kokain | |
ES2157957T3 (es) | Procedimientos para inhibir la endometriosis. | |
DE69735442D1 (de) | Antidiabetische mittel | |
DE59510370D1 (de) | [a]-ANNELIERTE PYRROLDERIVATE UND DEREN ANWENDUNG IN DER PHARMAZIE | |
DE69814394D1 (de) | Verwendung von levobupivacain | |
DE69928226T8 (de) | Chemokin rezeptor antagonisten und verwendung | |
DE69402165D1 (de) | Hemmung von Seborrhoe und Akne | |
BR9506552A (pt) | Método de inibição de integrase retroviral | |
NO944915L (no) | Öking av trombomodulinekspresjon | |
PT1039900E (pt) | Agentes terapeuticos | |
GR3025568T3 (en) | Medicament for therapeutic and prophylactic treatment of diseases caused by smooth muscle cell hyperplasia. | |
WO2000071520A3 (en) | Aryl substituted alkylamines capable of activating nicotinic cholinergic receptors | |
CA2289017A1 (en) | The use of a nitroxide or a prodrug thereof in the prophylactic and therapeutic treatment of cancer | |
NO991734L (no) | Pyrazolinoner for behandling av potensforstyrrelser | |
IT1288399B1 (it) | Medicamento per il trattamento terapeutico della maculopatia legata all'eta', della maculopatia non legata all'eta' e per la profilassi | |
DK0768083T3 (da) | Anvendelse af sertralin til at behandle patienter med post myocardisk infarkt | |
DE69813681D1 (de) | Neue triazole als therapeutische mittel gegen pilzinfektionen | |
FR2701479B1 (fr) | Nouveaux dérivés hétérocycliques de l'aminométhyl-4 pipéridine, leur préparation et leur application en thérapeutique. | |
DK0617023T3 (da) | Benzimidazolderivater, deres fremstilling og anvendelse | |
ES2159087T3 (es) | Oxindoles sustituidos con adamantilo como agentes farmaceuticos. |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
8364 | No opposition during term of opposition |