HUP9903765A2 - Eljárás 3-(1-piperazinil)-1,2-benzizotiazol előállítására, valamint ennek közbenső termékei - Google Patents

Eljárás 3-(1-piperazinil)-1,2-benzizotiazol előállítására, valamint ennek közbenső termékei

Info

Publication number
HUP9903765A2
HUP9903765A2 HU9903765A HUP9903765A HUP9903765A2 HU P9903765 A2 HUP9903765 A2 HU P9903765A2 HU 9903765 A HU9903765 A HU 9903765A HU P9903765 A HUP9903765 A HU P9903765A HU P9903765 A2 HUP9903765 A2 HU P9903765A2
Authority
HU
Hungary
Prior art keywords
piperazinyl
benzisothiazole
compounds
intermediates
preparing
Prior art date
Application number
HU9903765A
Other languages
English (en)
Inventor
Darrell E. Fox
John F. Lambert
Terry G. Sinay
Stanley W. Walinsky
Original Assignee
Pfizer Inc.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer Inc. filed Critical Pfizer Inc.
Publication of HUP9903765A2 publication Critical patent/HUP9903765A2/hu
Publication of HUP9903765A3 publication Critical patent/HUP9903765A3/hu
Publication of HU225921B1 publication Critical patent/HU225921B1/hu

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D275/00—Heterocyclic compounds containing 1,2-thiazole or hydrogenated 1,2-thiazole rings
    • C07D275/04—Heterocyclic compounds containing 1,2-thiazole or hydrogenated 1,2-thiazole rings condensed with carbocyclic rings or ring systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00—Drugs for disorders of the muscular or neuromuscular system
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/22—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with hetero atoms directly attached to ring nitrogen atoms
    • C07D295/26—Sulfur atoms

Abstract

A találmány tárgyát a (IIa) általánős képletű cianő-fenil-tiő-vegyületek képezik, ahől a képletben R1 jelentése (a) vagy (b) képletűcsőpőrt. A (IIa) általánős képletű vegyületek kiindűlási vegyületkéntalkalmazhatók a 3-(1-piperazinil)-1,2-benzizőtiazől és sóielőállításáhőz. A találmány tárgyáhőz tartőzik tővábbá ezen vegyületekelőállítására szőlgáló eljárás is. A találmány szerinti eljárássalelőállítőtt 3-(1-piperazinil)-1,2-benzizőtiazől közbenső termék aneűrőleptikűs hatású ciprazidőn előállításánál. ŕ
HU9903765A 1995-11-07 1996-10-11 Process and intermediates for preparing 3-(1-piperazinyl)-1,2-benzisothiazole HU225921B1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US630195P 1995-11-07 1995-11-07
PCT/IB1996/001079 WO1997017336A1 (en) 1995-11-07 1996-10-11 Processes and intermediates for preparing 3-(1-piperazinyl)-1,2-benzisothiazole

Publications (3)

Publication Number Publication Date
HUP9903765A2 true HUP9903765A2 (hu) 2000-03-28
HUP9903765A3 HUP9903765A3 (en) 2001-12-28
HU225921B1 HU225921B1 (en) 2008-01-28

Family

ID=21720240

Family Applications (1)

Application Number Title Priority Date Filing Date
HU9903765A HU225921B1 (en) 1995-11-07 1996-10-11 Process and intermediates for preparing 3-(1-piperazinyl)-1,2-benzisothiazole

Country Status (29)

Country Link
US (1) US6111105A (hu)
EP (1) EP0874834B1 (hu)
JP (1) JP3152938B2 (hu)
KR (1) KR100315939B1 (hu)
CN (1) CN1071324C (hu)
AR (2) AR004279A1 (hu)
AT (1) ATE198071T1 (hu)
AU (1) AU698443B2 (hu)
BR (1) BR9611366A (hu)
CA (1) CA2236940C (hu)
CO (1) CO4480028A1 (hu)
CZ (1) CZ290600B6 (hu)
DE (1) DE69611253T2 (hu)
DK (1) DK0874834T3 (hu)
ES (1) ES2152564T3 (hu)
GR (1) GR3035215T3 (hu)
HU (1) HU225921B1 (hu)
MX (1) MX9803599A (hu)
MY (1) MY116579A (hu)
NO (1) NO309811B1 (hu)
NZ (1) NZ318844A (hu)
PE (1) PE17298A1 (hu)
PL (1) PL185048B1 (hu)
PT (1) PT874834E (hu)
RU (1) RU2147302C1 (hu)
TR (1) TR199800814T2 (hu)
TW (1) TW358807B (hu)
WO (1) WO1997017336A1 (hu)
ZA (1) ZA969315B (hu)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
UY27668A1 (es) 2002-02-20 2003-10-31 Pfizer Prod Inc Composición de ziprasidona y controles sintéticos
US20040048876A1 (en) * 2002-02-20 2004-03-11 Pfizer Inc. Ziprasidone composition and synthetic controls
EP1628973A2 (en) 2003-10-24 2006-03-01 Teva Pharmaceutical Industries Ltd. Processes for preparation of ziprasidone
US7777037B2 (en) * 2004-10-27 2010-08-17 Dr. Reddy's Laboratories Limited Ziprasidone process
CN105891392A (zh) * 2016-03-29 2016-08-24 北京万全德众医药生物技术有限公司 一种用液相色谱法分离测定盐酸鲁拉西酮中间体有关物质的方法
CN107064323A (zh) * 2016-12-05 2017-08-18 北京万全德众医药生物技术有限公司 一种用液相色谱法分离测定盐酸鲁拉西酮及其有关物质的方法

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4590196A (en) * 1984-08-23 1986-05-20 Bristol-Myers Company Analgesic 1,2-benzisothiazol-3-ylpiperazine derivatives
JPH06220030A (ja) * 1993-01-22 1994-08-09 Sumitomo Pharmaceut Co Ltd ３−アミノ−１，２−ベンズイソチアゾール誘導体の製造法
JP3701044B2 (ja) * 1995-04-24 2005-09-28 住友精化株式会社 シアノベンゼンスルフェニルハライドおよびそれを用いる３−置換ベンゾイソチアゾールの製造方法
JP3996228B2 (ja) * 1996-10-11 2007-10-24 住友精化株式会社 ３−ピペラジニルベンズイソチアゾール類の製造法

Also Published As

Publication number Publication date
EP0874834B1 (en) 2000-12-13
DE69611253T2 (de) 2001-04-05
ZA969315B (en) 1998-05-06
JP3152938B2 (ja) 2001-04-03
PE17298A1 (es) 1998-04-16
EP0874834A1 (en) 1998-11-04
KR19990067381A (ko) 1999-08-16
PL326630A1 (en) 1998-10-12
MX9803599A (es) 1998-09-30
GR3035215T3 (en) 2001-04-30
KR100315939B1 (ko) 2002-01-16
AR004279A1 (es) 1998-11-04
HUP9903765A3 (en) 2001-12-28
AU698443B2 (en) 1998-10-29
TW358807B (en) 1999-05-21
AU7092696A (en) 1997-05-29
RU2147302C1 (ru) 2000-04-10
CO4480028A1 (es) 1997-07-09
WO1997017336A1 (en) 1997-05-15
ES2152564T3 (es) 2001-02-01
JPH10512595A (ja) 1998-12-02
HU225921B1 (en) 2008-01-28
ATE198071T1 (de) 2000-12-15
NO982051L (no) 1998-07-03
NO309811B1 (no) 2001-04-02
DE69611253D1 (de) 2001-01-18
CA2236940A1 (en) 1997-05-15
NO982051D0 (no) 1998-05-06
NZ318844A (en) 1999-04-29
DK0874834T3 (da) 2001-02-19
PT874834E (pt) 2001-04-30
CN1071324C (zh) 2001-09-19
MY116579A (en) 2004-02-28
PL185048B1 (pl) 2003-02-28
BR9611366A (pt) 1999-02-23
AR032373A2 (es) 2003-11-05
CA2236940C (en) 2001-08-21
CN1201457A (zh) 1998-12-09
TR199800814T2 (xx) 1998-07-21
US6111105A (en) 2000-08-29
CZ137898A3 (cs) 1999-03-17
CZ290600B6 (cs) 2002-08-14

Similar Documents

Publication Publication Date Title
NO178764C (no) Fremgangsmåte ved fremstilling av oksetanoner
FI942457A0 (fi) Substituoitujen piperidiinien valmistus
SE7501365L (hu)
HUP9903765A2 (hu) Eljárás 3-(1-piperazinil)-1,2-benzizotiazol előállítására, valamint ennek közbenső termékei
ES446993A1 (es) Un procedimiento para la preparacion de nuevos derivados de benzofenona.
MY127851A (en) Process for the preparation of 5-(1-piperazinyl) benzofuran-2-carboxamide by transition metal-catalysed amination
SE7501375L (hu)
IL59053A (en) N-azolyl-acetanilides,their manufacture and their use as herbicides
FI925258A (fi) Foerfarande foer framstaellning av 2-substituerade 4,6-dialkoxipyrimidiner
HUP0202383A2 (hu) Eljárás 2-(2-aril-morfolin-il)-etanol-származékok előállítása és közbenső termékek
FR2467202B1 (hu)
SE7509069L (sv) Forfarande for framstellning av cyklopropylmetylamin-derivat.
DK0521766T3 (da) Hidtil ukendt fremgangsmåde til syntese af enantiomerer af 3-aminochromanderivater
HUP9901985A2 (hu) Eljárás 3-fenil-1-[(metilén-dioxi)-fenil]-2-indánkarbonsav- és ciklopentapiridin-származékok, és intermedierjeik előállítására, valamint új intermedierjeik
NO924113L (no) Fremgangsmaate for fremstilling av substituerte indoler
HUT44502A (en) Process for producing 3-amino-dihydropyridine derivatives and pharmaceutical compositions containing them
JPS53137931A (en) Novel cyclic sestaterpenes
HUP0000298A2 (hu) Eljárás aril-béta-diketon-, aril-pirimidin-keton-származékok és növényvédőszerek közbenső termékeinek előállítására
IT1270834B (it) Disolfuro chinolico
JPS5265279A (en) 2-styril-3,1-benzoxazin-4-one derivatives
FI791865A (fi) Karbazolderivat
JPS51133277A (en) A process for preparing novel carbostyril derivatives
CH613698A5 (en) Process for the preparation of novel 5-amino-7-phenyl-2,3-dihydro-1H-1,4-diazepines
JPS523033A (en) Novel dipeptides
JPS51113891A (en) Method for preparing 7-substituted alkaneamido-3-substituted thiomethy l-3-cephem-4-carboxylic acids

Legal Events

Date Code Title Description
MM4A Lapse of definitive patent protection due to non-payment of fees