ES2148725T3 - Nuevas formulaciones galenicas estables conteniendo un compuesto de bencimidazol acido-labil, y su proceso de obtencion. - Google Patents

Nuevas formulaciones galenicas estables conteniendo un compuesto de bencimidazol acido-labil, y su proceso de obtencion.

Info

Publication number
ES2148725T3
ES2148725T3 ES96901349T ES96901349T ES2148725T3 ES 2148725 T3 ES2148725 T3 ES 2148725T3 ES 96901349 T ES96901349 T ES 96901349T ES 96901349 T ES96901349 T ES 96901349T ES 2148725 T3 ES2148725 T3 ES 2148725T3
Authority
ES
Spain
Prior art keywords
compound
labil
acid
formulations containing
benzmidazole
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES96901349T
Other languages
English (en)
Inventor
Rodes Montserrat Ballester
Boven Marinus Van
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Esteve Pharmaceuticals SA
Original Assignee
Laboratorios del Dr Esteve SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=8289322&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ES2148725(T3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Laboratorios del Dr Esteve SA filed Critical Laboratorios del Dr Esteve SA
Application granted granted Critical
Publication of ES2148725T3 publication Critical patent/ES2148725T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
    • A61K31/4439—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. omeprazole
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5073—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5073—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings
    • A61K9/5078—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings with drug-free core
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Plural Heterocyclic Compounds (AREA)

Abstract

NUEVAS FORMULACIONES GALENICAS ESTABLES QUE CONTIENEN UN COMPUESTO DE BENZIMIDAZOL DE ACIDO-LABIL, Y PROCESO DE PRODUCCION. ESTAS FORMULACIONES CONTIENEN UN NUCLEO NEUTRAL EN EL QUE SE APLICA UNA CAPA QUE CONTIENE EL INGREDIENTE ACTIVO Y QUE ESTA CONSTITUIDA POR EL COMPUESTO DE BENZIMIDAZOL QUE TIENE LA FORMULA GENERAL (I), UN POLIMERO SOLUBLE EN AGUA Y VEHICULOS DE REACCION NO ALCALINA, Y SOBRE LOS QUE SE APLICA UNA SEGUNDA CAPA AISLANTE QUE TIENE UN POLIMERO SOLUBLE EN AGUA, UN PIGMENTO Y TALCO, Y AL MENOS UNA CAPA ENTERICA QUE CONTIENE UN POLIMERO, UN PLASTIFICANTE Y TALCO.
ES96901349T 1995-02-01 1996-01-26 Nuevas formulaciones galenicas estables conteniendo un compuesto de bencimidazol acido-labil, y su proceso de obtencion. Expired - Lifetime ES2148725T3 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
ES09500181A ES2094694B1 (es) 1995-02-01 1995-02-01 Nueva formulacion farmaceuticamente estable de un compuesto de bencimidazol y su proceso de obtencion.
PCT/ES1996/000013 WO1996023500A1 (es) 1995-02-01 1996-01-26 Nuevas formulaciones galenicas estables conteniendo un compuesto de bencimidazol acido-labil, y su proceso de obtencion

Publications (1)

Publication Number Publication Date
ES2148725T3 true ES2148725T3 (es) 2000-10-16

Family

ID=8289322

Family Applications (3)

Application Number Title Priority Date Filing Date
ES09500181A Expired - Fee Related ES2094694B1 (es) 1995-02-01 1995-02-01 Nueva formulacion farmaceuticamente estable de un compuesto de bencimidazol y su proceso de obtencion.
ES99116334T Expired - Lifetime ES2238796T3 (es) 1995-02-01 1996-01-26 Nuevas formulaciones galenicas estabilizadas que comprenden un compuesto de bencimidazol labil en medio acido y su preparacion.
ES96901349T Expired - Lifetime ES2148725T3 (es) 1995-02-01 1996-01-26 Nuevas formulaciones galenicas estables conteniendo un compuesto de bencimidazol acido-labil, y su proceso de obtencion.

Family Applications Before (2)

Application Number Title Priority Date Filing Date
ES09500181A Expired - Fee Related ES2094694B1 (es) 1995-02-01 1995-02-01 Nueva formulacion farmaceuticamente estable de un compuesto de bencimidazol y su proceso de obtencion.
ES99116334T Expired - Lifetime ES2238796T3 (es) 1995-02-01 1996-01-26 Nuevas formulaciones galenicas estabilizadas que comprenden un compuesto de bencimidazol labil en medio acido y su preparacion.

Country Status (20)

Country Link
US (1) US5626875A (es)
EP (2) EP0773025B1 (es)
JP (1) JP4183746B2 (es)
KR (1) KR100331290B1 (es)
AR (1) AR002702A1 (es)
AT (2) ATE292967T1 (es)
AU (1) AU4540396A (es)
CA (1) CA2184842C (es)
DE (3) DE69634613T2 (es)
DK (2) DK0773025T3 (es)
ES (3) ES2094694B1 (es)
FI (1) FI121730B (es)
HU (1) HU229219B1 (es)
IL (1) IL116673A (es)
IN (1) IN186596B (es)
PT (2) PT773025E (es)
SI (2) SI0773025T1 (es)
TW (1) TW503115B (es)
WO (1) WO1996023500A1 (es)
ZA (1) ZA96683B (es)

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DE69634613D1 (de) 2005-05-19
HUP9603014A3 (en) 2000-12-28
HU229219B1 (en) 2013-09-30
CA2184842C (en) 2007-08-07
ATE292967T1 (de) 2005-04-15
KR100331290B1 (ko) 2002-11-22
PT993830E (pt) 2005-06-30
IL116673A (en) 2000-10-31
FI121730B (fi) 2011-03-31
TW503115B (en) 2002-09-21
FI963916A0 (fi) 1996-09-30
EP0993830B1 (en) 2005-04-13
FI963916A (fi) 1996-09-30
ZA96683B (en) 1997-09-23
DK0993830T3 (da) 2005-08-08
EP0993830A2 (en) 2000-04-19
IL116673A0 (en) 1996-05-14
PT773025E (pt) 2000-10-31
DE29623938U1 (de) 2000-10-05
ES2238796T3 (es) 2005-09-01
ES2094694B1 (es) 1997-12-16
CA2184842A1 (en) 1996-08-08
EP0773025B1 (en) 2000-06-07
AU4540396A (en) 1996-08-21
DE69608767D1 (de) 2000-07-13
JPH09511257A (ja) 1997-11-11
DE69634613T2 (de) 2006-03-09
EP0773025A1 (en) 1997-05-14
HUP9603014A2 (hu) 1998-03-30
IN186596B (es) 2001-10-06
DK0773025T3 (da) 2000-10-09
US5626875A (en) 1997-05-06
WO1996023500A1 (es) 1996-08-08
ES2094694A1 (es) 1997-01-16
AR002702A1 (es) 1998-04-29
SI0993830T1 (en) 2005-10-31
ATE193649T1 (de) 2000-06-15
SI0773025T1 (en) 2000-10-31
JP4183746B2 (ja) 2008-11-19
EP0993830A3 (en) 2001-10-04

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