ES2144386T5 - Ligando para el activador del receptor de NF-kappa b, el ligando es miembro de la superfamilia de TNF - Google Patents
Ligando para el activador del receptor de NF-kappa b, el ligando es miembro de la superfamilia de TNF Download PDFInfo
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- ES2144386T5 ES2144386T5 ES97952609T ES97952609T ES2144386T5 ES 2144386 T5 ES2144386 T5 ES 2144386T5 ES 97952609 T ES97952609 T ES 97952609T ES 97952609 T ES97952609 T ES 97952609T ES 2144386 T5 ES2144386 T5 ES 2144386T5
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Classifications
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- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
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- C07K16/241—Tumor Necrosis Factors
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/52—Cytokines; Lymphokines; Interferons
- C07K14/525—Tumour necrosis factor [TNF]
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
- C07K14/70578—NGF-receptor/TNF-receptor superfamily, e.g. CD27, CD30, CD40, CD95
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
- C07K14/715—Receptors; Cell surface antigens; Cell surface determinants for cytokines; for lymphokines; for interferons
- C07K14/7151—Receptors; Cell surface antigens; Cell surface determinants for cytokines; for lymphokines; for interferons for tumor necrosis factor [TNF], for lymphotoxin [LT]
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/2875—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the NGF/TNF superfamily, e.g. CD70, CD95L, CD153, CD154
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
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- A—HUMAN NECESSITIES
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/73—Inducing cell death, e.g. apoptosis, necrosis or inhibition of cell proliferation
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/76—Antagonist effect on antigen, e.g. neutralization or inhibition of binding
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/01—Fusion polypeptide containing a localisation/targetting motif
- C07K2319/02—Fusion polypeptide containing a localisation/targetting motif containing a signal sequence
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/30—Non-immunoglobulin-derived peptide or protein having an immunoglobulin constant or Fc region, or a fragment thereof, attached thereto
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/32—Fusion polypeptide fusions with soluble part of a cell surface receptor, "decoy receptors"
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/70—Fusion polypeptide containing domain for protein-protein interaction
- C07K2319/73—Fusion polypeptide containing domain for protein-protein interaction containing coiled-coiled motif (leucine zippers)
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Medicinal Chemistry (AREA)
- Immunology (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Biochemistry (AREA)
- Molecular Biology (AREA)
- Zoology (AREA)
- Toxicology (AREA)
- Gastroenterology & Hepatology (AREA)
- Engineering & Computer Science (AREA)
- Cell Biology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Wood Science & Technology (AREA)
- Analytical Chemistry (AREA)
- General Engineering & Computer Science (AREA)
- Microbiology (AREA)
- Biotechnology (AREA)
- Physics & Mathematics (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Peptides Or Proteins (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Transition And Organic Metals Composition Catalysts For Addition Polymerization (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
Applications Claiming Priority (7)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US5997896P | 1996-12-23 | 1996-12-23 | |
| US59978P | 1996-12-23 | ||
| US7718197P | 1997-03-07 | 1997-03-07 | |
| US77181P | 1997-03-07 | ||
| US6467197P | 1997-10-14 | 1997-10-14 | |
| US64671P | 1997-10-14 | ||
| PCT/US1997/023775 WO1998028426A2 (en) | 1996-12-23 | 1997-12-22 | Ligand for receptor activator of nf-kappa b, ligand is member of tnf superfamily |
Publications (4)
| Publication Number | Publication Date |
|---|---|
| ES2144386T1 ES2144386T1 (es) | 2000-06-16 |
| ES2144386T3 ES2144386T3 (es) | 2009-01-16 |
| ES2144386T5 true ES2144386T5 (es) | 2012-12-07 |
| ES2144386T9 ES2144386T9 (es) | 2013-02-18 |
Family
ID=27369779
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES97952609T Expired - Lifetime ES2144386T5 (es) | 1996-12-23 | 1997-12-22 | Ligando para el activador del receptor de NF-kappa b, el ligando es miembro de la superfamilia de TNF |
Country Status (13)
| Country | Link |
|---|---|
| US (21) | US6017729A (OSRAM) |
| EP (5) | EP2314695A3 (OSRAM) |
| JP (7) | JP2002509431A (OSRAM) |
| AT (2) | ATE401404T1 (OSRAM) |
| AU (2) | AU713471C (OSRAM) |
| CA (1) | CA2274987C (OSRAM) |
| DE (4) | DE122010000048I1 (OSRAM) |
| DK (1) | DK0951551T4 (OSRAM) |
| ES (1) | ES2144386T5 (OSRAM) |
| IL (1) | IL130492A (OSRAM) |
| LU (1) | LU91758I2 (OSRAM) |
| PT (1) | PT951551E (OSRAM) |
| WO (2) | WO1998028426A2 (OSRAM) |
Families Citing this family (174)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20050060764A1 (en) * | 2003-09-17 | 2005-03-17 | Susan Gregory | Mouse model for bone metabolism |
| IL117175A (en) * | 1995-02-20 | 2005-11-20 | Sankyo Co | Osteoclastogenesis inhibitory factor protein |
| US6919434B1 (en) | 1995-02-20 | 2005-07-19 | Sankyo Co., Ltd. | Monoclonal antibodies that bind OCIF |
| US20050147611A1 (en) * | 1995-12-22 | 2005-07-07 | Amgen Inc. | Combination therapy for conditions leading to bone loss |
| US7632922B1 (en) * | 1995-12-22 | 2009-12-15 | Amgen, Inc. | Osteoprotegerin |
| US6479254B2 (en) | 1996-03-22 | 2002-11-12 | Human Genome Sciences, Inc. | Apoptosis inducing molecule II |
| US6635743B1 (en) | 1996-03-22 | 2003-10-21 | Human Genome Sciences, Inc. | Apoptosis inducing molecule II and methods of use |
| US6495520B2 (en) | 1996-03-22 | 2002-12-17 | Human Genome Sciences, Inc. | Apoptosis Inducing Molecule II and methods of use |
| US7964190B2 (en) | 1996-03-22 | 2011-06-21 | Human Genome Sciences, Inc. | Methods and compositions for decreasing T-cell activity |
| AU5697098A (en) * | 1996-12-13 | 1998-07-03 | Schering Corporation | Mammalian cell surface antigens; related reagents |
| CA2274803C (en) * | 1996-12-23 | 2012-05-22 | Immunex Corporation | Receptor activator of nf-kappa b, receptor is member of tnf receptor superfamily |
| AU713471C (en) | 1996-12-23 | 2002-04-18 | Immunex Corporation | Ligand for receptor activator of NF-kappa B, ligand is member of TNF superfamily |
| HU229476B1 (en) * | 1997-04-15 | 2014-01-28 | Daiichi Sankyo Company | Antibodies against obm |
| AU2008200700C1 (en) * | 1997-04-15 | 2013-04-04 | Daiichi Sankyo Co., Ltd | Novel Protein and Process for Producing The Same |
| US6316408B1 (en) | 1997-04-16 | 2001-11-13 | Amgen Inc. | Methods of use for osetoprotegerin binding protein receptors |
| ATE363533T1 (de) | 1997-04-16 | 2007-06-15 | Amgen Inc | Osteoprotegerin bindende proteine und rezeptoren |
| CA2229449A1 (en) * | 1997-04-25 | 1998-10-25 | Takeda Chemical Industries, Ltd. | Novel receptor protein and its use |
| AU7705098A (en) * | 1997-05-29 | 1998-12-30 | Human Genome Sciences, Inc. | Human tumor necrosis factor receptor-like protein 8 |
| KR100547395B1 (ko) | 1997-09-24 | 2006-02-01 | 산쿄 가부시키가이샤 | 골대사이상증의 진단방법 |
| US7019119B2 (en) | 1997-12-12 | 2006-03-28 | The Rockefeller University | Protein belonging to the TNF superfamily involved in signal transduction, nucleic acids encoding same, and methods of use thereof |
| US7063960B2 (en) | 1997-12-12 | 2006-06-20 | The Rockefeller University | Protein belonging to the TNF superfamily involved in signal transduction, nucleic acids encoding same, and methods of use thereof |
| WO1999029865A2 (en) * | 1997-12-12 | 1999-06-17 | The Rockefeller University | A protein belonging to the tnf superfamily, nucleic acids encoding same, and methods of use thereof |
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1997
- 1997-12-22 AU AU56180/98A patent/AU713471C/en not_active Expired
- 1997-12-22 IL IL130492A patent/IL130492A/en not_active IP Right Cessation
- 1997-12-22 EP EP10182863A patent/EP2314695A3/en not_active Withdrawn
- 1997-12-22 ES ES97952609T patent/ES2144386T5/es not_active Expired - Lifetime
- 1997-12-22 JP JP52906898A patent/JP2002509431A/ja not_active Withdrawn
- 1997-12-22 DK DK97952609.2T patent/DK0951551T4/da active
- 1997-12-22 PT PT97952609T patent/PT951551E/pt unknown
- 1997-12-22 DE DE122010000048C patent/DE122010000048I1/de active Pending
- 1997-12-22 JP JP52904598A patent/JP4138013B2/ja not_active Expired - Lifetime
- 1997-12-22 EP EP97953438A patent/EP0946725B1/en not_active Expired - Lifetime
- 1997-12-22 WO PCT/US1997/023775 patent/WO1998028426A2/en not_active Ceased
- 1997-12-22 DE DE0951551T patent/DE951551T1/de active Pending
- 1997-12-22 AT AT97952609T patent/ATE401404T1/de active
- 1997-12-22 CA CA2274987A patent/CA2274987C/en not_active Expired - Lifetime
- 1997-12-22 AU AU57184/98A patent/AU713473B2/en not_active Ceased
- 1997-12-22 US US08/996,139 patent/US6017729A/en not_active Expired - Lifetime
- 1997-12-22 DE DE69738841T patent/DE69738841D1/de not_active Expired - Lifetime
- 1997-12-22 EP EP97952609A patent/EP0951551B9/en not_active Expired - Lifetime
- 1997-12-22 EP EP08010882A patent/EP2003203A1/en not_active Withdrawn
- 1997-12-22 WO PCT/US1997/023866 patent/WO1998028424A2/en not_active Ceased
- 1997-12-22 US US08/995,659 patent/US6242213B1/en not_active Expired - Lifetime
- 1997-12-22 EP EP10182860A patent/EP2371962A3/en not_active Withdrawn
- 1997-12-22 AT AT97953438T patent/ATE497001T1/de active
- 1997-12-22 DE DE69740107T patent/DE69740107D1/de not_active Expired - Lifetime
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1999
- 1999-12-17 US US09/466,496 patent/US6528482B1/en not_active Expired - Lifetime
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2000
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- 2000-05-24 US US09/577,800 patent/US6479635B1/en not_active Expired - Lifetime
- 2000-10-13 US US09/688,459 patent/US6838262B1/en not_active Expired - Lifetime
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2001
- 2001-05-25 US US09/865,363 patent/US6740522B2/en not_active Expired - Lifetime
- 2001-05-30 US US09/871,291 patent/US6562948B2/en not_active Expired - Fee Related
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- 2001-06-08 US US09/877,650 patent/US6649164B2/en not_active Expired - Lifetime
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2003
- 2003-04-01 US US10/405,878 patent/US7262274B2/en not_active Expired - Fee Related
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2004
- 2004-03-16 US US10/802,133 patent/US7411050B2/en not_active Expired - Fee Related
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2006
- 2006-07-26 JP JP2006203204A patent/JP4054354B2/ja not_active Expired - Lifetime
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2007
- 2007-07-30 US US11/881,911 patent/US7932375B2/en not_active Expired - Fee Related
- 2007-10-12 JP JP2007266393A patent/JP4203105B2/ja not_active Expired - Lifetime
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2008
- 2008-02-25 JP JP2008043360A patent/JP4242913B2/ja not_active Expired - Lifetime
- 2008-06-24 US US12/214,914 patent/US7744886B2/en not_active Expired - Fee Related
- 2008-11-11 JP JP2008288844A patent/JP2009051862A/ja not_active Withdrawn
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2010
- 2010-06-15 US US12/802,801 patent/US8377690B2/en not_active Expired - Fee Related
- 2010-07-02 JP JP2010152282A patent/JP5096527B2/ja not_active Expired - Lifetime
- 2010-08-04 US US12/850,368 patent/US8333963B2/en not_active Expired - Fee Related
- 2010-11-24 LU LU91758C patent/LU91758I2/fr unknown
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2011
- 2011-04-22 US US13/092,718 patent/US8153775B2/en not_active Expired - Fee Related
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2012
- 2012-03-19 US US13/424,179 patent/US8569456B2/en not_active Expired - Fee Related
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2013
- 2013-02-12 US US13/765,597 patent/US8715683B2/en not_active Expired - Fee Related
- 2013-10-28 US US14/065,133 patent/US20140186887A1/en not_active Abandoned
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2014
- 2014-05-02 US US14/268,858 patent/US20140235832A1/en not_active Abandoned
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