ES2099604T3 - Nuevos compuestos a83543 y procedimiento para su produccion. - Google Patents
Nuevos compuestos a83543 y procedimiento para su produccion.Info
- Publication number
- ES2099604T3 ES2099604T3 ES94912774T ES94912774T ES2099604T3 ES 2099604 T3 ES2099604 T3 ES 2099604T3 ES 94912774 T ES94912774 T ES 94912774T ES 94912774 T ES94912774 T ES 94912774T ES 2099604 T3 ES2099604 T3 ES 2099604T3
- Authority
- ES
- Spain
- Prior art keywords
- nrrl
- new
- compounds
- components
- procedure
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- 150000001875 compounds Chemical class 0.000 title abstract 2
- 238000000034 method Methods 0.000 title abstract 2
- 241001661449 Espinosa Species 0.000 abstract 1
- 241000238631 Hexapoda Species 0.000 abstract 1
- 238000000855 fermentation Methods 0.000 abstract 1
- 230000004151 fermentation Effects 0.000 abstract 1
- 230000000749 insecticidal effect Effects 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- 238000002360 preparation method Methods 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H17/00—Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
- C07H17/04—Heterocyclic radicals containing only oxygen as ring hetero atoms
- C07H17/08—Hetero rings containing eight or more ring members, e.g. erythromycins
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N43/00—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
- A01N43/02—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with one or more oxygen or sulfur atoms as the only ring hetero atoms
- A01N43/04—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with one or more oxygen or sulfur atoms as the only ring hetero atoms with one hetero atom
- A01N43/22—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with one or more oxygen or sulfur atoms as the only ring hetero atoms with one hetero atom rings with more than six members
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
- A61P33/14—Ectoparasiticides, e.g. scabicides
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
- C12N1/20—Bacteria; Culture media therefor
- C12N1/205—Bacterial isolates
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P19/00—Preparation of compounds containing saccharide radicals
- C12P19/44—Preparation of O-glycosides, e.g. glucosides
- C12P19/60—Preparation of O-glycosides, e.g. glucosides having an oxygen of the saccharide radical directly bound to a non-saccharide heterocyclic ring or a condensed ring system containing a non-saccharide heterocyclic ring, e.g. coumermycin, novobiocin
- C12P19/62—Preparation of O-glycosides, e.g. glucosides having an oxygen of the saccharide radical directly bound to a non-saccharide heterocyclic ring or a condensed ring system containing a non-saccharide heterocyclic ring, e.g. coumermycin, novobiocin the hetero ring having eight or more ring members and only oxygen as ring hetero atoms, e.g. erythromycin, spiramycin, nystatin
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12R—INDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C - C12Q, RELATING TO MICROORGANISMS
- C12R2001/00—Microorganisms ; Processes using microorganisms
- C12R2001/01—Bacteria or Actinomycetales ; using bacteria or Actinomycetales
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S424/00—Drug, bio-affecting and body treating compositions
- Y10S424/08—Systemic pesticides
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S424/00—Drug, bio-affecting and body treating compositions
- Y10S424/10—Insect repellent
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S435/00—Chemistry: molecular biology and microbiology
- Y10S435/8215—Microorganisms
- Y10S435/822—Microorganisms using bacteria or actinomycetales
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- General Health & Medical Sciences (AREA)
- Biotechnology (AREA)
- Genetics & Genomics (AREA)
- Biochemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Microbiology (AREA)
- General Engineering & Computer Science (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Medicinal Chemistry (AREA)
- Tropical Medicine & Parasitology (AREA)
- Biomedical Technology (AREA)
- Virology (AREA)
- Molecular Biology (AREA)
- Veterinary Medicine (AREA)
- Environmental Sciences (AREA)
- Dentistry (AREA)
- Agronomy & Crop Science (AREA)
- Pest Control & Pesticides (AREA)
- Plant Pathology (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
- Saccharide Compounds (AREA)
- Devices That Are Associated With Refrigeration Equipment (AREA)
- Manufacturing Of Printed Wiring (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines Containing Plant Substances (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US3052293A | 1993-03-12 | 1993-03-12 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES2099604T3 true ES2099604T3 (es) | 1997-05-16 |
Family
ID=21854619
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES94912774T Expired - Lifetime ES2099604T3 (es) | 1993-03-12 | 1994-03-11 | Nuevos compuestos a83543 y procedimiento para su produccion. |
Country Status (14)
| Country | Link |
|---|---|
| US (3) | US5840861A (cg-RX-API-DMAC7.html) |
| EP (1) | EP0688332B1 (cg-RX-API-DMAC7.html) |
| JP (1) | JP4258575B2 (cg-RX-API-DMAC7.html) |
| AT (1) | ATE150758T1 (cg-RX-API-DMAC7.html) |
| AU (1) | AU685107B2 (cg-RX-API-DMAC7.html) |
| BR (1) | BR9406587A (cg-RX-API-DMAC7.html) |
| CA (1) | CA2156194C (cg-RX-API-DMAC7.html) |
| DE (1) | DE69402308T2 (cg-RX-API-DMAC7.html) |
| DK (1) | DK0688332T3 (cg-RX-API-DMAC7.html) |
| ES (1) | ES2099604T3 (cg-RX-API-DMAC7.html) |
| FI (1) | FI107266B (cg-RX-API-DMAC7.html) |
| IL (1) | IL108979A (cg-RX-API-DMAC7.html) |
| TW (1) | TW294672B (cg-RX-API-DMAC7.html) |
| WO (1) | WO1994020518A1 (cg-RX-API-DMAC7.html) |
Families Citing this family (59)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0837870B1 (en) * | 1995-06-14 | 2002-07-24 | Dow AgroSciences LLC | Synthetic modification to spinosyn compounds |
| DE19823396A1 (de) * | 1998-05-26 | 1999-12-02 | Bayer Ag | Synergistische insektizide Mischungen |
| DE19823397B4 (de) | 1998-05-26 | 2011-07-28 | Bayer CropScience AG, 40789 | Verwendung von Spinosynen zum Einsatz als Bodeninsektizide |
| KR100641778B1 (ko) | 1998-07-02 | 2006-11-06 | 일라이 릴리 앤드 캄파니 | 인간 이 억제 제제 |
| US6933318B1 (en) | 1999-08-12 | 2005-08-23 | Eli Lilly And Company | Topical organic ectoparasiticidal formulations |
| US6927210B1 (en) | 1999-08-12 | 2005-08-09 | Eli Lilly And Company | Ectoparasiticidal aqueous suspension formulations of spinosyns |
| AU6606400A (en) * | 1999-08-12 | 2001-03-13 | Eli Lilly And Company | Topical treatment for insect pests in companion animals |
| WO2001011963A1 (en) | 1999-08-12 | 2001-02-22 | Eli Lilly And Company | Oral treatment of companion animals with ectoparasiticidal spinosyns |
| JP2003508050A (ja) | 1999-08-27 | 2003-03-04 | バイエル アクチェンゲゼルシャフト | スピノシン生合成の酵素活性をコードする核酸 |
| US6455504B1 (en) * | 1999-09-13 | 2002-09-24 | Dow Agrosciences Llc | Pesticidal macrolides |
| AUPQ441699A0 (en) | 1999-12-02 | 2000-01-06 | Eli Lilly And Company | Pour-on formulations |
| AUPQ634300A0 (en) * | 2000-03-20 | 2000-04-15 | Eli Lilly And Company | Synergistic formulations |
| US6585990B1 (en) | 2001-03-05 | 2003-07-01 | Dow Agrosciences, Llc | Compositions and devices using a spinosyn compound for control of insects |
| IL157974A0 (en) * | 2001-03-21 | 2004-03-28 | Dow Agrosciences Llc | Pesticidal macrolides |
| ES2276929T3 (es) * | 2001-03-29 | 2007-07-01 | Bayer Cropscience Ag | Compuestos intermedios para la obtencion de espinosinas. |
| AR033022A1 (es) | 2001-03-30 | 2003-12-03 | Dow Agrosciences Llc | Genes biosinteticos para la produccion de insecticida de butenilespinosina |
| US6727228B2 (en) * | 2001-04-25 | 2004-04-27 | Johnson & Johnson Consumer Companies, Inc. | Pediculicidal and ovacidal treatment compositions and methods for killing head lice and their eggs |
| DE10135550A1 (de) * | 2001-07-20 | 2003-01-30 | Bayer Cropscience Ag | Verfahren zum Herstellen von neuen Spinosyn-Derivaten |
| US7772194B2 (en) | 2001-09-17 | 2010-08-10 | Eli Lilly And Company | Pesticidal formulations |
| TWI330183B (cg-RX-API-DMAC7.html) * | 2001-10-22 | 2010-09-11 | Eisai R&D Man Co Ltd | |
| CN1633237B (zh) | 2002-02-19 | 2010-05-26 | 道农业科学公司 | 新的产生spinosyn的聚酮合酶 |
| ES2315740T3 (es) * | 2003-11-04 | 2009-04-01 | Intervet International Bv | Formulaciones ectoparasiticidas de espinosinas y pesticidas de azol. |
| EP1849363A1 (en) * | 2006-03-09 | 2007-10-31 | Cheminova A/S | Synergistic combination of glutamate- and GABA-gated chloride agonist pesticide and at least one of Vitamin E or Niacin |
| US8178658B2 (en) * | 2008-02-12 | 2012-05-15 | Dow Agrosciences, Llc | Pesticidal compositions |
| CN101560477B (zh) * | 2008-04-16 | 2012-04-25 | 上海医药工业研究院 | 发酵多杀菌素产生菌的培养基 |
| US9514283B2 (en) | 2008-07-09 | 2016-12-06 | Baxter International Inc. | Dialysis system having inventory management including online dextrose mixing |
| PT2343975E (pt) | 2008-09-22 | 2012-12-26 | Entarco Sa | Composições anti-incrustantes de espinosina, métodos de utilização das mesmas e artigos protegidos da fixação de organismos de incrustação biológica |
| US8268975B2 (en) | 2009-04-03 | 2012-09-18 | Dow Agrosciences Llc | Demulsification compositions, systems and methods for demulsifying and separating aqueous emulsions |
| TW201041507A (en) * | 2009-04-30 | 2010-12-01 | Dow Agrosciences Llc | Pesticide compositions exhibiting enhanced activity and methods for preparing same |
| TW201041510A (en) | 2009-04-30 | 2010-12-01 | Dow Agrosciences Llc | Pesticide compositions exhibiting enhanced activity |
| TW201041509A (en) * | 2009-04-30 | 2010-12-01 | Dow Agrosciences Llc | Pesticide compositions exhibiting enhanced activity |
| TW201041508A (en) | 2009-04-30 | 2010-12-01 | Dow Agrosciences Llc | Pesticide compositions exhibiting enhanced activity |
| EP2445506B1 (en) | 2009-06-24 | 2014-12-31 | Entarco SA | The use of spinosyns and spinosyn compositions against diseases caused by protozoans, viral infections and cancer |
| JP2013531976A (ja) | 2010-05-11 | 2013-08-15 | ダウ アグロサイエンシィズ エルエルシー | spnK菌株 |
| US20160184340A1 (en) | 2010-12-22 | 2016-06-30 | Christine Kritikou | The use of spinosyns and spinosyn compositions as local anesthetics and as antiarrhythmic agents |
| KR101960110B1 (ko) * | 2010-12-29 | 2019-03-19 | 다우 아그로사이언시즈 엘엘씨 | 곤충 방제 방법 |
| US8741603B2 (en) | 2011-05-03 | 2014-06-03 | Agrigenetics Inc. | Enhancing spinosyn production with oxygen binding proteins |
| US9404107B2 (en) | 2011-05-03 | 2016-08-02 | Dow Agrosciences Llc | Integration of genes into the chromosome of Saccharopolyspora spinosa |
| EP2520658B1 (en) | 2011-05-03 | 2015-10-07 | Dow AgroSciences LLC | Enhancing spinosyn production with oxygen binding proteins |
| US9631195B2 (en) | 2011-12-28 | 2017-04-25 | Dow Agrosciences Llc | Identification and characterization of the spinactin biosysnthesis gene cluster from spinosyn producing saccharopolyspora spinosa |
| TR201909461T4 (tr) | 2012-02-06 | 2019-07-22 | Boehringer Ingelheim Animal Health Usa Inc | Si̇stemi̇k olarak etki̇ eden akti̇f maddeleri̇ i̇çeren parazi̇ti̇si̇dal oral veteri̇nerli̇ğe ai̇t bi̇leşi̇mler, bunlarin yöntemleri̇ ve kullanimlari |
| JO3626B1 (ar) | 2012-02-23 | 2020-08-27 | Merial Inc | تركيبات موضعية تحتوي على فيبرونيل و بيرميثرين و طرق استخدامها |
| AU2012233000B2 (en) * | 2012-09-28 | 2016-01-21 | Elanco New Zealand | Ectoparasitic Treatment Method and Composition |
| NZ726251A (en) | 2014-04-17 | 2017-11-24 | Merial Inc | Use of malononitrile compounds for protecting animals from parasites |
| ES2842592T3 (es) | 2014-05-19 | 2021-07-14 | Boehringer Ingelheim Animal Health Usa Inc | Compuestos antihelmínticos |
| NZ728102A (en) | 2014-06-19 | 2018-04-27 | Merial Inc | Parasiticidal compositions comprising indole derivatives, methods and uses thereof |
| US10306887B2 (en) | 2014-08-05 | 2019-06-04 | The Board Of Regents Of The University Of Texas Systems | Composition and methods for modulation of the octopamine receptor and its homologs |
| UY36570A (es) | 2015-02-26 | 2016-10-31 | Merial Inc | Formulaciones inyectables de acción prolongada que comprenden un agente activo isoxazolina, métodos y usos de las mismas |
| ES2916216T3 (es) | 2015-05-20 | 2022-06-29 | Boehringer Ingelheim Animal Health Usa Inc | Compuestos de depsipéptidos antihelmínticos |
| WO2018039508A1 (en) | 2016-08-25 | 2018-03-01 | Merial, Inc. | Method for reducing unwanted effects in parasiticidal treatments |
| AU2017361099A1 (en) | 2016-11-16 | 2019-06-06 | Boehringer Ingelheim Animal Health USA Inc. | Anthelmintic depsipeptide compounds |
| WO2018226893A2 (en) | 2017-06-06 | 2018-12-13 | Zymergen Inc. | A high-throughput (htp) genomic engineering platform for improving saccharopolyspora spinosa |
| IL279977B2 (en) | 2018-07-09 | 2024-06-01 | Boehringer Ingelheim Animal Health Usa Inc | Heterocyclic anthelmintic compounds |
| US10730901B2 (en) | 2018-07-27 | 2020-08-04 | Aperta Biosciences, Llc | Spinosyn formulations for treatment of demodex-induced ocular and facial conditions |
| US11773066B2 (en) | 2018-11-20 | 2023-10-03 | Boehringer Ingelheim Animal Health USA Inc. | Indazolylcyanoethylamino compound, compositions of same, method of making, and methods of using thereof |
| WO2020150032A1 (en) | 2019-01-16 | 2020-07-23 | Boehringer Ingelheim Animal Health USA Inc. | Topical compositions comprising a neonicotinoid and a macrocyclic lactone, methods and uses thereof |
| JP7637630B2 (ja) | 2019-03-19 | 2025-02-28 | ベーリンガー インゲルハイム フェトメディカ ゲーエムベーハー | 駆虫性アザベンゾチオフェンおよびアザベンゾフラン化合物 |
| CN110734467B (zh) * | 2019-09-10 | 2021-08-27 | 北大方正集团有限公司 | 一种从发酵液中提取纯化多杀霉素的方法 |
| CA3183100A1 (en) | 2020-05-29 | 2021-12-02 | Boehringer Ingelheim Pharma Gmbh & Co. Kg | Anthelmintic heterocyclic compounds |
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|---|---|---|---|---|
| US2881162A (en) * | 1953-11-16 | 1959-04-07 | Abbott Lab | Recovery process |
| US3725385A (en) * | 1970-11-02 | 1973-04-03 | Abbott Lab | Process for the demethylation of 3-amino macrolides |
| US4206206A (en) * | 1977-03-24 | 1980-06-03 | Kowa Company, Ltd. | Antibiotics of the KA-6606 series and pharmaceutical compositions thereof |
| AU520409B2 (en) * | 1977-05-25 | 1982-01-28 | Commonwealth Scientific And Industrial Research Organisation | Controlled release composition |
| US4213966A (en) * | 1977-06-02 | 1980-07-22 | E. R. Squibb & Sons, Inc. | Method for isolating polyether antibiotics |
| US4148883A (en) * | 1977-08-18 | 1979-04-10 | Pfizer Inc. | Antibiotics produced by new species of nocardia |
| US4224314A (en) * | 1979-03-02 | 1980-09-23 | Pfizer Inc. | Antibiotics produced by species of Nocardia |
| JPS5943929B2 (ja) * | 1979-08-13 | 1984-10-25 | サッポロビール株式会社 | 多糖体rbs物質,その製法およびそれを有効成分とする抗腫瘍性剤 |
| AU539868B2 (en) * | 1979-09-12 | 1984-10-18 | Eli Lilly And Company | Device for drug delivery to ruminants |
| US4273920A (en) * | 1979-09-12 | 1981-06-16 | Eli Lilly And Company | Polymerization process and product |
| US4321329A (en) * | 1979-10-02 | 1982-03-23 | The Upjohn Company | Saccharopolyspora culture |
| US4251511A (en) * | 1979-10-02 | 1981-02-17 | The Upjohn Company | Antibiotic and fermentation process of preparing |
| US4293651A (en) * | 1979-10-02 | 1981-10-06 | The Upjohn Company | Process for producing antibiotic using saccharopolyspora |
| EP0043197A1 (en) * | 1980-07-02 | 1982-01-06 | Beecham Group Plc | Beta-Lactam antibiotic, its preparation and use |
| DE3162169D1 (en) * | 1980-07-15 | 1984-03-15 | Kowa Co | Process for production of antibiotics, and novel antibiotics produced thereby |
| US4448970A (en) * | 1981-02-19 | 1984-05-15 | The Upjohn Company | Nargenicin derivatives |
| IT1195299B (it) * | 1981-11-27 | 1988-10-12 | Pierrel Spa | Procedimento chimico di sintesi per la preparazione di antibiotici macrolidici |
| US4482707A (en) * | 1981-12-08 | 1984-11-13 | Toyo Jozo Kabushiki Kaisha | Aminoglycoside antibiotic saccharocins |
| JPS58189114A (ja) * | 1982-04-30 | 1983-11-04 | Ss Pharmaceut Co Ltd | 抗潰瘍剤 |
| US4508647A (en) * | 1982-07-26 | 1985-04-02 | Bristol-Myers Company | Antitumor antibiotics BBM-2040A and BBM-2040B |
| IT1194181B (it) * | 1983-03-30 | 1988-09-14 | Erba Farmitalia | Procedimento migliorato per la purificazione della tilosina |
| US4530835A (en) * | 1983-07-08 | 1985-07-23 | Warner-Lambert Company | CL-1577 Antibiotic compounds and their production |
| US4560509A (en) * | 1983-11-16 | 1985-12-24 | Eli Lilly And Company | Antibiotic A39079 factor S-1 |
| JPS625990A (ja) * | 1985-06-20 | 1987-01-12 | Sumitomo Chem Co Ltd | 抗生物質およびその製造方法 |
| ES8800986A1 (es) * | 1985-07-27 | 1987-12-01 | Pfizer | Un procedimiento para la produccion de un nuevo derivado de avermectina |
| JPS62226925A (ja) * | 1986-03-28 | 1987-10-05 | Ss Pharmaceut Co Ltd | 抗マイコプラズマ剤 |
| US4831016A (en) * | 1986-10-31 | 1989-05-16 | Merck & Co., Inc. | Reduced avermectin derivatives |
| US5003056A (en) * | 1987-12-24 | 1991-03-26 | Nippon Kayaku Kabushiki Kaisha | Antibiotic NK86-0279, process for production of the same and application of the same |
| US5362634A (en) * | 1989-10-30 | 1994-11-08 | Dowelanco | Process for producing A83543 compounds |
| PE5591A1 (es) * | 1988-12-19 | 1991-02-15 | Lilly Co Eli | Un nuevo grupo de compuestos de macrolida |
| US5028536A (en) * | 1989-03-15 | 1991-07-02 | Bristol-Myers Squibb Company | Antitumor antibiotic BMY-41339 |
| EP0454820A4 (en) * | 1989-10-30 | 1992-03-11 | Eli Lilly And Company | A83543 recovery process |
| US5202242A (en) * | 1991-11-08 | 1993-04-13 | Dowelanco | A83543 compounds and processes for production thereof |
| CN1073483A (zh) * | 1991-11-08 | 1993-06-23 | 道伊兰科公司 | 一种发酵杀虫剂化合物及其制备方法 |
| US5227295A (en) * | 1991-11-08 | 1993-07-13 | Dowelanco | Process for isolating A83543 and its components |
-
1994
- 1994-03-11 ES ES94912774T patent/ES2099604T3/es not_active Expired - Lifetime
- 1994-03-11 EP EP94912774A patent/EP0688332B1/en not_active Expired - Lifetime
- 1994-03-11 DE DE69402308T patent/DE69402308T2/de not_active Expired - Lifetime
- 1994-03-11 AU AU65187/94A patent/AU685107B2/en not_active Expired
- 1994-03-11 JP JP52034194A patent/JP4258575B2/ja not_active Expired - Lifetime
- 1994-03-11 AT AT94912774T patent/ATE150758T1/de active
- 1994-03-11 BR BR9406587A patent/BR9406587A/pt not_active IP Right Cessation
- 1994-03-11 DK DK94912774.0T patent/DK0688332T3/da active
- 1994-03-11 CA CA002156194A patent/CA2156194C/en not_active Expired - Lifetime
- 1994-03-11 WO PCT/US1994/002674 patent/WO1994020518A1/en not_active Ceased
- 1994-03-15 IL IL10897994A patent/IL108979A/en not_active IP Right Cessation
- 1994-03-21 TW TW083102553A patent/TW294672B/zh not_active IP Right Cessation
-
1995
- 1995-02-08 US US08/385,497 patent/US5840861A/en not_active Expired - Lifetime
- 1995-06-07 US US08/483,440 patent/US5670486A/en not_active Expired - Lifetime
- 1995-06-07 US US08/474,026 patent/US5670364A/en not_active Expired - Lifetime
- 1995-09-11 FI FI954246A patent/FI107266B/fi not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| CA2156194C (en) | 2008-01-08 |
| EP0688332A1 (en) | 1995-12-27 |
| BR9406587A (pt) | 1996-01-02 |
| EP0688332B1 (en) | 1997-03-26 |
| DE69402308D1 (de) | 1997-04-30 |
| DE69402308T2 (de) | 1997-10-23 |
| ATE150758T1 (de) | 1997-04-15 |
| US5670364A (en) | 1997-09-23 |
| FI107266B (fi) | 2001-06-29 |
| DK0688332T3 (da) | 1997-10-13 |
| US5670486A (en) | 1997-09-23 |
| WO1994020518A1 (en) | 1994-09-15 |
| TW294672B (cg-RX-API-DMAC7.html) | 1997-01-01 |
| US5840861A (en) | 1998-11-24 |
| IL108979A (en) | 1999-09-22 |
| JP4258575B2 (ja) | 2009-04-30 |
| CA2156194A1 (en) | 1994-09-15 |
| FI954246L (fi) | 1995-09-11 |
| AU6518794A (en) | 1994-09-26 |
| AU685107B2 (en) | 1998-01-15 |
| IL108979A0 (en) | 1994-06-24 |
| JPH08507533A (ja) | 1996-08-13 |
| FI954246A0 (fi) | 1995-09-11 |
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