ES2091737T1 - Formulados farmaceuticos de fluoxetina. - Google Patents

Formulados farmaceuticos de fluoxetina.

Info

Publication number
ES2091737T1
ES2091737T1 ES95304975T ES95304975T ES2091737T1 ES 2091737 T1 ES2091737 T1 ES 2091737T1 ES 95304975 T ES95304975 T ES 95304975T ES 95304975 T ES95304975 T ES 95304975T ES 2091737 T1 ES2091737 T1 ES 2091737T1
Authority
ES
Spain
Prior art keywords
fluoxetine
pharmaceutical
formulates
dispersible tablets
appropriate
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
ES95304975T
Other languages
English (en)
Other versions
ES2091737T3 (es
Inventor
Mendizabal Flavia Arce
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Lilly SA
Original Assignee
Lilly SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=8286976&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ES2091737(T1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Lilly SA filed Critical Lilly SA
Publication of ES2091737T1 publication Critical patent/ES2091737T1/es
Application granted granted Critical
Publication of ES2091737T3 publication Critical patent/ES2091737T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A61K9/2054—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
    • A61K31/138—Aryloxyalkylamines, e.g. propranolol, tamoxifen, phenoxybenzamine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
    • A61K9/0056—Mouth soluble or dispersible forms; Suckable, eatable, chewable coherent forms; Forms rapidly disintegrating in the mouth; Lozenges; Lollipops; Bite capsules; Baked products; Baits or other oral forms for animals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0087—Galenical forms not covered by A61K9/02 - A61K9/7023
    • A61K9/0095—Drinks; Beverages; Syrups; Compositions for reconstitution thereof, e.g. powders or tablets to be dispersed in a glass of water; Veterinary drenches
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A61K9/2059—Starch, including chemically or physically modified derivatives; Amylose; Amylopectin; Dextrin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2095—Tabletting processes; Dosage units made by direct compression of powders or specially processed granules, by eliminating solvents, by melt-extrusion, by injection molding, by 3D printing
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/26—Psychostimulants, e.g. nicotine, cocaine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2013—Organic compounds, e.g. phospholipids, fats
    • A61K9/2018—Sugars, or sugar alcohols, e.g. lactose, mannitol; Derivatives thereof, e.g. polysorbates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/2027—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Zoology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Physiology (AREA)
  • Nutrition Science (AREA)
  • Neurosurgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Psychiatry (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Pain & Pain Management (AREA)
  • Inorganic Chemistry (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

SE PRESENTAN FORMULACIONES FARMACEUTICAS DE FLUOXETINA O UNA SAL DE ADICION ACIDA DE LA MISMA ADECUADAS PARA LA MANUFACTURA DE TABLETAS DISPERSIBLES MEDIANTE COMPRESION DIRECTA Y QUE COMPRENDEN ADEMAS DEL INGREDIENTE ACTIVO, LOS EXCIPIENTES Y COADYUDANTES APROPIADOS, QUE SE SELECCIONAN ENTRE DESINTEGRANTES, DILUYENTES, LUBRICANTES, ANTIADHERENTES, ENDULZANTES, SABORIZANTES Y OPCIONALMENTE, COLORANTES. LAS FORMULACIONES SON ADECUADAS PARA MANUFACTURAR TABLETAS DISPERSIBLES QUE SE DESINTEGRAN EN MENOS DE TRES MINUTOS EN AGUA ENTRE 19 (GRADOS) Y 21 (GRADOS) C Y SON APROPIADAS PARA EL TRATAMIENTO DE LA DEPRESION.
ES95304975T 1994-07-20 1995-07-17 Formulaciones farmaceuticas de fluoxetina. Expired - Lifetime ES2091737T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
ES09401593A ES2082723B1 (es) 1994-07-20 1994-07-20 Formulacion farmaceutica de fluoxetina en forma dispersable.

Publications (2)

Publication Number Publication Date
ES2091737T1 true ES2091737T1 (es) 1996-11-16
ES2091737T3 ES2091737T3 (es) 2001-06-01

Family

ID=8286976

Family Applications (2)

Application Number Title Priority Date Filing Date
ES09401593A Expired - Fee Related ES2082723B1 (es) 1994-07-20 1994-07-20 Formulacion farmaceutica de fluoxetina en forma dispersable.
ES95304975T Expired - Lifetime ES2091737T3 (es) 1994-07-20 1995-07-17 Formulaciones farmaceuticas de fluoxetina.

Family Applications Before (1)

Application Number Title Priority Date Filing Date
ES09401593A Expired - Fee Related ES2082723B1 (es) 1994-07-20 1994-07-20 Formulacion farmaceutica de fluoxetina en forma dispersable.

Country Status (31)

Country Link
US (1) US5747068A (es)
EP (3) EP0693281B1 (es)
JP (1) JPH0840884A (es)
KR (1) KR100360130B1 (es)
CN (2) CN1440745B (es)
AT (1) ATE200733T1 (es)
AU (2) AU692550B2 (es)
BR (1) BR9503386A (es)
CO (1) CO4410195A1 (es)
CY (1) CY2241B1 (es)
CZ (1) CZ287378B6 (es)
DE (2) DE69520768T2 (es)
DK (1) DK0693281T3 (es)
ES (2) ES2082723B1 (es)
FI (3) FI121262B (es)
GR (2) GR960300064T1 (es)
HK (1) HK1012573A1 (es)
HU (1) HU228859B1 (es)
IL (1) IL114641A (es)
MY (1) MY114776A (es)
NO (1) NO312225B2 (es)
NZ (1) NZ272610A (es)
PE (1) PE33996A1 (es)
PL (1) PL181359B1 (es)
PT (1) PT693281E (es)
RU (1) RU2145850C1 (es)
SI (1) SI0693281T1 (es)
TR (1) TR199500878A2 (es)
TW (1) TW404840B (es)
UA (1) UA41346C2 (es)
ZA (1) ZA956074B (es)

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EA000818B1 (ru) * 1995-12-27 2000-04-24 Жансен Фармасетика Н.В. Биоадгезивная твердая дозированная лекарственная форма
EA001089B1 (ru) * 1996-02-29 2000-10-30 Фудзисава Фармасьютикал Ко., Лтд. ТАБЛЕТКИ, СОДЕРЖАЩИЕ β-ЛАКТАМНЫЙ АНТИБИОТИК, И СПОСОБ ИХ ИЗГОТОВЛЕНИЯ
US8071128B2 (en) 1996-06-14 2011-12-06 Kyowa Hakko Kirin Co., Ltd. Intrabuccally rapidly disintegrating tablet and a production method of the tablets
US5910319A (en) 1997-05-29 1999-06-08 Eli Lilly And Company Fluoxetine enteric pellets and methods for their preparation and use
US5904937A (en) * 1997-10-03 1999-05-18 Fmc Corporation Taste masked pharmaceutical compositions
TR200000944T2 (tr) * 1997-10-09 2000-11-21 Perio Products Ltd. Geciktirmeli tam çözünümlü mide-bağırsak bölgesi ilaç verme sistemi.
JP4504467B2 (ja) * 1998-07-30 2010-07-14 佐藤製薬株式会社 口腔内崩壊性錠剤
US6399101B1 (en) 2000-03-30 2002-06-04 Mova Pharmaceutical Corp. Stable thyroid hormone preparations and method of making same
OA12596A (en) * 2001-05-01 2006-06-08 Pfizer Prod Inc Method for manufacturing a low dose pharmaceuticalcomposition.
US6509040B1 (en) 2001-06-22 2003-01-21 R.P. Scherer Corporation Fast dispersing dosage forms essentially free of mammalian gelatin
US9358214B2 (en) 2001-10-04 2016-06-07 Adare Pharmaceuticals, Inc. Timed, sustained release systems for propranolol
US6645526B2 (en) * 2001-11-13 2003-11-11 Mylan Pharmaceuticals, Inc. Storage stable thyroxine active drug formulations and methods for their production
US20030099699A1 (en) * 2001-11-13 2003-05-29 Hanshew Dwight D. Storage stable thyroxine active drug formulations and methods for their production
US20030113366A1 (en) * 2001-12-14 2003-06-19 Macgregor Alexander Reverse-micellar delivery system for controlled transportation and enhanced absorption of agents
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US8367111B2 (en) * 2002-12-31 2013-02-05 Aptalis Pharmatech, Inc. Extended release dosage forms of propranolol hydrochloride
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DE10351448A1 (de) * 2003-11-04 2005-06-09 Bayer Healthcare Ag Geschmackstoffhaltige Arzneimittelformulierungen mit verbesserten pharmazeutischen Eigenschaften
US8747895B2 (en) * 2004-09-13 2014-06-10 Aptalis Pharmatech, Inc. Orally disintegrating tablets of atomoxetine
US9884014B2 (en) 2004-10-12 2018-02-06 Adare Pharmaceuticals, Inc. Taste-masked pharmaceutical compositions
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US20060105038A1 (en) * 2004-11-12 2006-05-18 Eurand Pharmaceuticals Limited Taste-masked pharmaceutical compositions prepared by coacervation
US9161918B2 (en) 2005-05-02 2015-10-20 Adare Pharmaceuticals, Inc. Timed, pulsatile release systems
SI1883397T1 (sl) * 2005-05-17 2010-04-30 Actelion Pharmaceuticals Ltd Disperzibilne tablete bosertana
CN100353943C (zh) * 2005-07-04 2007-12-12 广州固志医药科技有限公司 乳酸氟罗沙星分散片及其制备方法
CN101257800B (zh) * 2005-07-18 2012-07-18 好利用医疗公司 包含法莫替丁和布洛芬的药物
US20080020040A1 (en) * 2006-07-18 2008-01-24 Horizon Therapeutics, Inc. Unit dose form for administration of ibuprofen
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KR101438629B1 (ko) 2013-02-04 2014-09-05 현대자동차 주식회사 체결 장치 및 그 제어 방법
RU2700164C2 (ru) 2013-12-27 2019-09-13 Чугаи Сейяку Кабусики Кайся Твердые препараты, содержащие тофоглифлозин, и способ их получения
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CN107334742B (zh) * 2017-08-18 2020-01-31 山东力诺制药有限公司 一种盐酸氟西汀分散片及其制备方法
KR102453105B1 (ko) * 2020-10-26 2022-10-07 현대제철 주식회사 침지노즐 크리닝 장치
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Also Published As

Publication number Publication date
KR100360130B1 (ko) 2003-01-29
CO4410195A1 (es) 1997-01-09
DK0693281T3 (da) 2001-05-21
FI20011852A (fi) 2001-09-20
CN1440745A (zh) 2003-09-10
FI121262B (fi) 2010-09-15
DE69520768T2 (de) 2001-08-23
PL181359B1 (pl) 2001-07-31
HU9502154D0 (en) 1995-09-28
FI20011851A (fi) 2001-09-20
US5747068A (en) 1998-05-05
EP0693281A3 (en) 1996-10-30
DE693281T1 (de) 1997-04-03
NZ272610A (en) 1997-08-22
SI0693281T1 (en) 2001-12-31
EP0693281A2 (en) 1996-01-24
PL309721A1 (en) 1996-01-22
DE69520768D1 (de) 2001-05-31
NO952863L (no) 1996-01-22
TW404840B (en) 2000-09-11
CY2241B1 (en) 2003-07-04
FI953515A0 (fi) 1995-07-20
NO952863D0 (no) 1995-07-19
AU8317498A (en) 1998-11-05
EP0693281B1 (en) 2001-04-25
AU692550B2 (en) 1998-06-11
AU2509895A (en) 1996-02-01
EP1070501A1 (en) 2001-01-24
TR199500878A2 (tr) 1996-06-21
ES2082723A1 (es) 1996-03-16
HK1012573A1 (en) 1999-08-06
HUT75036A (en) 1997-03-28
HU228859B1 (en) 2013-06-28
EP1072262A1 (en) 2001-01-31
MY114776A (en) 2003-01-31
UA41346C2 (uk) 2001-09-17
PE33996A1 (es) 1996-09-09
CZ188095A3 (en) 1996-02-14
RU2145850C1 (ru) 2000-02-27
ES2091737T3 (es) 2001-06-01
PT693281E (pt) 2001-08-30
CN1101187C (zh) 2003-02-12
AU707210B2 (en) 1999-07-08
JPH0840884A (ja) 1996-02-13
GR3035788T3 (en) 2001-07-31
CN1123142A (zh) 1996-05-29
CN1440745B (zh) 2012-03-21
ZA956074B (en) 1996-05-14
IL114641A0 (en) 1995-11-27
ES2082723B1 (es) 1996-10-01
BR9503386A (pt) 1996-02-27
NO312225B1 (no) 2002-04-15
FI953515A (fi) 1996-01-21
KR960003720A (ko) 1996-02-23
CZ287378B6 (en) 2000-11-15
IL114641A (en) 1999-04-11
NO312225B2 (no) 2002-04-15
GR960300064T1 (en) 1996-11-30
ATE200733T1 (de) 2001-05-15

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