ES2088098T3 - Compuestos farmaceuticos. - Google Patents

Compuestos farmaceuticos.

Info

Publication number
ES2088098T3
ES2088098T3 ES92303752T ES92303752T ES2088098T3 ES 2088098 T3 ES2088098 T3 ES 2088098T3 ES 92303752 T ES92303752 T ES 92303752T ES 92303752 T ES92303752 T ES 92303752T ES 2088098 T3 ES2088098 T3 ES 2088098T3
Authority
ES
Spain
Prior art keywords
pharmaceutical compounds
pharmaceutical
compounds
tablet containing
dirithromycin form
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES92303752T
Other languages
English (en)
Inventor
James Michael Greene
Holly Marie Hankins
Gregory Alan Stephenson
David Dale Wirth
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Eli Lilly and Co
Original Assignee
Eli Lilly and Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Eli Lilly and Co filed Critical Eli Lilly and Co
Application granted granted Critical
Publication of ES2088098T3 publication Critical patent/ES2088098T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/70Carbohydrates; Sugars; Derivatives thereof
    • A61K31/715Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/70Carbohydrates; Sugars; Derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/2004Excipients; Inactive ingredients
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/28Dragees; Coated pills or tablets, e.g. with film or compression coating
    • A61K9/2886Dragees; Coated pills or tablets, e.g. with film or compression coating having two or more different drug-free coatings; Tablets of the type inert core-drug layer-inactive layer
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H17/00Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
    • C07H17/04Heterocyclic radicals containing only oxygen as ring hetero atoms
    • C07H17/08Hetero rings containing eight or more ring members, e.g. erythromycins

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Genetics & Genomics (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Steroid Compounds (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Formation And Processing Of Food Products (AREA)

Abstract

SE PRESENTAN COMPUESTOS DE DISOLUCION DE ACETONA, 1 ANOL, 1 STRAN MEDIOS EFICIENTES PARA AISLAR LA FORMA II DE LA DIRITROMICINA. ASI MISMO SE PRESENTA UN PROCESO PARA AISLAR LA FORMA II DE LA DIRITROMICINA A PARTIR DE COMPUESTOS DE DISOLUCION O A PARTIR DE LA FORMA I DE LA DIRITROMICINA. TAMBIEN SE PRESENTA UN PROCESO PARA OBTENER LA FORMA II DE LA DIRITROMICINA A PARTIR DE LA DIRITROMICINA NO DISUELTA.
ES92303752T 1991-04-29 1992-04-27 Compuestos farmaceuticos. Expired - Lifetime ES2088098T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US69284291A 1991-04-29 1991-04-29

Publications (1)

Publication Number Publication Date
ES2088098T3 true ES2088098T3 (es) 1996-08-01

Family

ID=24782254

Family Applications (2)

Application Number Title Priority Date Filing Date
ES92303753T Expired - Lifetime ES2093779T3 (es) 1991-04-29 1992-04-27 Formulacion farmaceutica que contiene diritromicina.
ES92303752T Expired - Lifetime ES2088098T3 (es) 1991-04-29 1992-04-27 Compuestos farmaceuticos.

Family Applications Before (1)

Application Number Title Priority Date Filing Date
ES92303753T Expired - Lifetime ES2093779T3 (es) 1991-04-29 1992-04-27 Formulacion farmaceutica que contiene diritromicina.

Country Status (27)

Country Link
EP (2) EP0511799B1 (es)
JP (2) JP3333545B2 (es)
KR (2) KR100193742B1 (es)
CN (2) CN1069197C (es)
AT (2) ATE144425T1 (es)
AU (2) AU646734B2 (es)
BR (2) BR9201540A (es)
CA (2) CA2067274C (es)
CY (2) CY1946A (es)
CZ (2) CZ282021B6 (es)
DE (2) DE69211220T2 (es)
DK (2) DK0511800T3 (es)
ES (2) ES2093779T3 (es)
FI (2) FI101795B1 (es)
GR (2) GR3020439T3 (es)
HK (2) HK153696A (es)
HU (2) HU215917B (es)
IE (2) IE76296B1 (es)
IL (2) IL101705A (es)
MX (2) MX9201944A (es)
MY (2) MY109498A (es)
NO (2) NO179504C (es)
NZ (2) NZ242505A (es)
RU (2) RU2045953C1 (es)
TW (2) TW315371B (es)
YU (2) YU44492A (es)
ZA (2) ZA922776B (es)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TW271400B (es) * 1992-07-30 1996-03-01 Pfizer
CR5278A (es) * 1995-03-24 1996-07-04 Lilly Co Eli Formulacion oral de 2-metil-tieno-benzodiacepina
ATE272646T1 (de) * 1996-07-29 2004-08-15 Abbott Lab Herstellung von kristallinen form ii von clarithromycin
ID21762A (id) * 1996-09-24 1999-07-22 Lilly Co Eli Formulasi partikel bersaput
US6390690B1 (en) 2000-05-17 2002-05-21 3M Innovative Properties Company Fiber optic connector for coupling devices on intersecting planes
ES2401467T3 (es) * 2006-12-05 2013-04-19 Bristol-Myers Squibb Company Polimorfos de motilida
CN102145008B (zh) * 2010-12-29 2013-06-05 辰欣药业股份有限公司 一种地红霉素药物组合物及其制备方法
CN107151261B (zh) * 2017-06-09 2020-06-12 广州大光制药有限公司 一种地红霉素化合物的晶型及其结晶制备方法

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AT342770B (de) * 1975-04-07 1978-04-25 Thomae Gmbh Dr K Verfahren zur herstellung neuer erythromycinderivate
DE2515075C2 (de) * 1975-04-07 1985-10-24 Dr. Karl Thomae Gmbh, 7950 Biberach Erythromycinderivate, Verfahren zu ihrer Herstellung und diese Verbindungen enthaltende Arzneimittel
EP0184921A3 (en) * 1984-12-08 1986-10-29 Beecham Group Plc Erythromycin derivatives
DE3524572A1 (de) * 1985-07-10 1987-01-15 Thomae Gmbh Dr K Feste arzneimittelformen zur peroralen anwendung enthaltend 9-deoxo-11-deoxy-9,11-(imino(2-(2-methoxyethoxy)ethyliden)-oxy)-(9s)-erythromycin und verfahren zu ihrer herstellung

Also Published As

Publication number Publication date
FI101795B (fi) 1998-08-31
KR920019364A (ko) 1992-11-19
JP3333545B2 (ja) 2002-10-15
NO921617D0 (no) 1992-04-27
JPH05117289A (ja) 1993-05-14
DE69211220T2 (de) 1996-11-07
FI101795B1 (fi) 1998-08-31
CN1069197C (zh) 2001-08-08
EP0511799A1 (en) 1992-11-04
IE921345A1 (en) 1992-11-04
FI921876A0 (fi) 1992-04-27
DK0511799T3 (da) 1996-06-24
HUT62595A (en) 1993-05-28
RU2070203C1 (ru) 1996-12-10
ZA922776B (en) 1993-10-15
CN1066186A (zh) 1992-11-18
KR100193742B1 (ko) 1999-06-15
TW315371B (es) 1997-09-11
FI921876A (fi) 1992-10-30
IE74885B1 (en) 1997-08-13
KR920019365A (ko) 1992-11-19
RU2045953C1 (ru) 1995-10-20
MX9201944A (es) 1992-11-01
CN1066270A (zh) 1992-11-18
CZ282021B6 (cs) 1997-04-16
ATE144425T1 (de) 1996-11-15
FI921877A0 (fi) 1992-04-27
HUT63956A (en) 1993-11-29
AU1525792A (en) 1992-11-05
NZ242505A (en) 1993-06-25
NO180450C (no) 1997-04-23
MY109498A (en) 1997-02-28
IL101704A (en) 1998-02-22
CY1975A (en) 1997-09-05
MY114226A (en) 2002-09-30
ATE138924T1 (de) 1996-06-15
NO179504C (no) 1996-10-23
HK153696A (en) 1996-08-16
GR3021706T3 (en) 1997-02-28
HU9203168D0 (en) 1992-12-28
ES2093779T3 (es) 1997-01-01
CY1946A (en) 1992-04-27
JPH05117154A (ja) 1993-05-14
FI921877A (fi) 1992-10-30
IE76296B1 (en) 1997-10-08
IE921346A1 (en) 1992-11-04
IL101705A0 (en) 1992-12-30
NO921616D0 (no) 1992-04-27
IL101704A0 (en) 1992-12-30
CA2067275A1 (en) 1992-10-30
KR100194307B1 (ko) 1999-06-15
HK215096A (en) 1996-12-13
GR3020439T3 (en) 1996-10-31
CZ282218B6 (cs) 1997-06-11
CA2067275C (en) 2002-11-26
CA2067274C (en) 2002-10-15
DE69214710D1 (de) 1996-11-28
NO921617L (no) 1992-10-30
ZA922777B (en) 1993-10-15
EP0511799B1 (en) 1996-06-05
AU1525592A (en) 1992-11-05
AU655978B2 (en) 1995-01-19
HU9201398D0 (en) 1992-07-28
IL101705A (en) 1996-01-31
NO921616L (no) 1992-10-30
CS127792A3 (en) 1992-11-18
JP3135672B2 (ja) 2001-02-19
YU44492A (sh) 1994-06-24
YU44392A (sh) 1994-12-28
HU215917B (hu) 1999-03-29
EP0511800B1 (en) 1996-10-23
NZ242506A (en) 1993-09-27
DK0511800T3 (da) 1997-04-21
NO180450B (no) 1997-01-13
DE69211220D1 (de) 1996-07-11
MX9201946A (es) 1992-11-01
CN1030611C (zh) 1996-01-03
NO179504B (no) 1996-07-15
CS127692A3 (en) 1992-11-18
BR9201541A (pt) 1992-12-01
AU646734B2 (en) 1994-03-03
HU213613B (en) 1997-08-28
CA2067274A1 (en) 1992-10-30
BR9201540A (pt) 1992-12-01
DE69214710T2 (de) 1997-03-13
EP0511800A1 (en) 1992-11-04
TW216399B (es) 1993-11-21

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