YU44492A - Solvati diritromicina - Google Patents

Solvati diritromicina

Info

Publication number
YU44492A
YU44492A YU44492A YU44492A YU44492A YU 44492 A YU44492 A YU 44492A YU 44492 A YU44492 A YU 44492A YU 44492 A YU44492 A YU 44492A YU 44492 A YU44492 A YU 44492A
Authority
YU
Yugoslavia
Prior art keywords
diritromycin
solvates
tablet containing
dirithromycin form
containing dirithromycin
Prior art date
Application number
YU44492A
Other languages
English (en)
Serbian (sr)
Inventor
J.M. Green
H.M. Hankins
G.A. Stephenson
D.D. Wirth
Original Assignee
Eli Lilly And Co.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Eli Lilly And Co. filed Critical Eli Lilly And Co.
Publication of YU44492A publication Critical patent/YU44492A/sh

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/70Carbohydrates; Sugars; Derivatives thereof
    • A61K31/715Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/70Carbohydrates; Sugars; Derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/2004Excipients; Inactive ingredients
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/28Dragees; Coated pills or tablets, e.g. with film or compression coating
    • A61K9/2886Dragees; Coated pills or tablets, e.g. with film or compression coating having two or more different drug-free coatings; Tablets of the type inert core-drug layer-inactive layer
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H17/00Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
    • C07H17/04Heterocyclic radicals containing only oxygen as ring hetero atoms
    • C07H17/08Hetero rings containing eight or more ring members, e.g. erythromycins

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • Genetics & Genomics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Steroid Compounds (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Formation And Processing Of Food Products (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)

Abstract

SOLVATI DIRITROMICINA, opisani su aceton, 1-propanol, 2-propanol, i 1-butanol solvati makrolidnog antibiotika diritromicina koji su kao stabilni solvati pogodni za izolovanje farmaceutski prihvatljivog diritromicina u izuzetno dobrom prinosu i velike čistoće. Opisan je i postupak za dobijanje diritromicina oblika II iz pomenutih solvata i diritromicina oblika I.
YU44492A 1991-04-29 1992-04-24 Solvati diritromicina YU44492A (sh)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US69284291A 1991-04-29 1991-04-29

Publications (1)

Publication Number Publication Date
YU44492A true YU44492A (sh) 1994-06-24

Family

ID=24782254

Family Applications (2)

Application Number Title Priority Date Filing Date
YU44492A YU44492A (sh) 1991-04-29 1992-04-24 Solvati diritromicina
YU44392A YU44392A (sh) 1991-04-29 1992-04-24 Postupak za dobijanje farmaceutske formulacije diritromicina

Family Applications After (1)

Application Number Title Priority Date Filing Date
YU44392A YU44392A (sh) 1991-04-29 1992-04-24 Postupak za dobijanje farmaceutske formulacije diritromicina

Country Status (27)

Country Link
EP (2) EP0511799B1 (sh)
JP (2) JP3333545B2 (sh)
KR (2) KR100193742B1 (sh)
CN (2) CN1069197C (sh)
AT (2) ATE144425T1 (sh)
AU (2) AU646734B2 (sh)
BR (2) BR9201540A (sh)
CA (2) CA2067274C (sh)
CY (2) CY1946A (sh)
CZ (2) CZ282021B6 (sh)
DE (2) DE69211220T2 (sh)
DK (2) DK0511800T3 (sh)
ES (2) ES2093779T3 (sh)
FI (2) FI101795B1 (sh)
GR (2) GR3020439T3 (sh)
HK (2) HK153696A (sh)
HU (2) HU215917B (sh)
IE (2) IE76296B1 (sh)
IL (2) IL101705A (sh)
MX (2) MX9201944A (sh)
MY (2) MY109498A (sh)
NO (2) NO179504C (sh)
NZ (2) NZ242505A (sh)
RU (2) RU2045953C1 (sh)
TW (2) TW315371B (sh)
YU (2) YU44492A (sh)
ZA (2) ZA922776B (sh)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TW271400B (sh) * 1992-07-30 1996-03-01 Pfizer
CR5278A (es) * 1995-03-24 1996-07-04 Lilly Co Eli Formulacion oral de 2-metil-tieno-benzodiacepina
ATE272646T1 (de) * 1996-07-29 2004-08-15 Abbott Lab Herstellung von kristallinen form ii von clarithromycin
ID21762A (id) * 1996-09-24 1999-07-22 Lilly Co Eli Formulasi partikel bersaput
US6390690B1 (en) 2000-05-17 2002-05-21 3M Innovative Properties Company Fiber optic connector for coupling devices on intersecting planes
ES2401467T3 (es) * 2006-12-05 2013-04-19 Bristol-Myers Squibb Company Polimorfos de motilida
CN102145008B (zh) * 2010-12-29 2013-06-05 辰欣药业股份有限公司 一种地红霉素药物组合物及其制备方法
CN107151261B (zh) * 2017-06-09 2020-06-12 广州大光制药有限公司 一种地红霉素化合物的晶型及其结晶制备方法

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AT342770B (de) * 1975-04-07 1978-04-25 Thomae Gmbh Dr K Verfahren zur herstellung neuer erythromycinderivate
DE2515075C2 (de) * 1975-04-07 1985-10-24 Dr. Karl Thomae Gmbh, 7950 Biberach Erythromycinderivate, Verfahren zu ihrer Herstellung und diese Verbindungen enthaltende Arzneimittel
EP0184921A3 (en) * 1984-12-08 1986-10-29 Beecham Group Plc Erythromycin derivatives
DE3524572A1 (de) * 1985-07-10 1987-01-15 Thomae Gmbh Dr K Feste arzneimittelformen zur peroralen anwendung enthaltend 9-deoxo-11-deoxy-9,11-(imino(2-(2-methoxyethoxy)ethyliden)-oxy)-(9s)-erythromycin und verfahren zu ihrer herstellung

Also Published As

Publication number Publication date
FI101795B (fi) 1998-08-31
KR920019364A (ko) 1992-11-19
JP3333545B2 (ja) 2002-10-15
NO921617D0 (no) 1992-04-27
JPH05117289A (ja) 1993-05-14
DE69211220T2 (de) 1996-11-07
FI101795B1 (fi) 1998-08-31
CN1069197C (zh) 2001-08-08
EP0511799A1 (en) 1992-11-04
IE921345A1 (en) 1992-11-04
FI921876A0 (fi) 1992-04-27
DK0511799T3 (da) 1996-06-24
HUT62595A (en) 1993-05-28
RU2070203C1 (ru) 1996-12-10
ZA922776B (en) 1993-10-15
CN1066186A (zh) 1992-11-18
KR100193742B1 (ko) 1999-06-15
TW315371B (sh) 1997-09-11
FI921876A (fi) 1992-10-30
IE74885B1 (en) 1997-08-13
KR920019365A (ko) 1992-11-19
RU2045953C1 (ru) 1995-10-20
MX9201944A (es) 1992-11-01
CN1066270A (zh) 1992-11-18
CZ282021B6 (cs) 1997-04-16
ATE144425T1 (de) 1996-11-15
FI921877A0 (fi) 1992-04-27
HUT63956A (en) 1993-11-29
AU1525792A (en) 1992-11-05
NZ242505A (en) 1993-06-25
NO180450C (no) 1997-04-23
MY109498A (en) 1997-02-28
IL101704A (en) 1998-02-22
CY1975A (en) 1997-09-05
MY114226A (en) 2002-09-30
ATE138924T1 (de) 1996-06-15
NO179504C (no) 1996-10-23
HK153696A (en) 1996-08-16
GR3021706T3 (en) 1997-02-28
HU9203168D0 (en) 1992-12-28
ES2093779T3 (es) 1997-01-01
CY1946A (en) 1992-04-27
JPH05117154A (ja) 1993-05-14
FI921877A (fi) 1992-10-30
IE76296B1 (en) 1997-10-08
IE921346A1 (en) 1992-11-04
IL101705A0 (en) 1992-12-30
NO921616D0 (no) 1992-04-27
IL101704A0 (en) 1992-12-30
CA2067275A1 (en) 1992-10-30
KR100194307B1 (ko) 1999-06-15
HK215096A (en) 1996-12-13
GR3020439T3 (en) 1996-10-31
CZ282218B6 (cs) 1997-06-11
CA2067275C (en) 2002-11-26
CA2067274C (en) 2002-10-15
DE69214710D1 (de) 1996-11-28
NO921617L (no) 1992-10-30
ZA922777B (en) 1993-10-15
EP0511799B1 (en) 1996-06-05
AU1525592A (en) 1992-11-05
AU655978B2 (en) 1995-01-19
HU9201398D0 (en) 1992-07-28
IL101705A (en) 1996-01-31
NO921616L (no) 1992-10-30
CS127792A3 (en) 1992-11-18
JP3135672B2 (ja) 2001-02-19
YU44392A (sh) 1994-12-28
HU215917B (hu) 1999-03-29
EP0511800B1 (en) 1996-10-23
NZ242506A (en) 1993-09-27
DK0511800T3 (da) 1997-04-21
NO180450B (no) 1997-01-13
DE69211220D1 (de) 1996-07-11
MX9201946A (es) 1992-11-01
CN1030611C (zh) 1996-01-03
NO179504B (no) 1996-07-15
CS127692A3 (en) 1992-11-18
BR9201541A (pt) 1992-12-01
AU646734B2 (en) 1994-03-03
HU213613B (en) 1997-08-28
CA2067274A1 (en) 1992-10-30
BR9201540A (pt) 1992-12-01
DE69214710T2 (de) 1997-03-13
ES2088098T3 (es) 1996-08-01
EP0511800A1 (en) 1992-11-04
TW216399B (sh) 1993-11-21

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