ES2076502T3 - Enantiomeros de derivados de 2-tetrahidrofurano, intermedios para los mismos y su preparacion. - Google Patents

Enantiomeros de derivados de 2-tetrahidrofurano, intermedios para los mismos y su preparacion.

Info

Publication number
ES2076502T3
ES2076502T3 ES91810477T ES91810477T ES2076502T3 ES 2076502 T3 ES2076502 T3 ES 2076502T3 ES 91810477 T ES91810477 T ES 91810477T ES 91810477 T ES91810477 T ES 91810477T ES 2076502 T3 ES2076502 T3 ES 2076502T3
Authority
ES
Spain
Prior art keywords
compound
formula
enantiomers
intermediates
preparation
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES91810477T
Other languages
English (en)
Spanish (es)
Inventor
Heinrich Estermann
William Joseph Houlihan
Prasad Koteswara Kapa
Russell Lee Underwood
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sandoz AG
Original Assignee
Sandoz AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sandoz AG filed Critical Sandoz AG
Application granted granted Critical
Publication of ES2076502T3 publication Critical patent/ES2076502T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/06—Phosphorus compounds without P—C bonds
    • C07F9/08—Esters of oxyacids of phosphorus
    • C07F9/09—Esters of phosphoric acids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/02—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
    • C07D307/04—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
    • C07D307/10—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having no double bonds between ring members or between ring members and non-ring members with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D307/12—Radicals substituted by oxygen atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/02—Antineoplastic agents specific for leukemia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/655—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having oxygen atoms, with or without sulfur, selenium, or tellurium atoms, as the only ring hetero atoms
    • C07F9/65515—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having oxygen atoms, with or without sulfur, selenium, or tellurium atoms, as the only ring hetero atoms the oxygen atom being part of a five-membered ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/6564—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having phosphorus atoms, with or without nitrogen, oxygen, sulfur, selenium or tellurium atoms, as ring hetero atoms
    • C07F9/6571—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having phosphorus atoms, with or without nitrogen, oxygen, sulfur, selenium or tellurium atoms, as ring hetero atoms having phosphorus and oxygen atoms as the only ring hetero atoms
    • C07F9/6574—Esters of oxyacids of phosphorus
    • C07F9/65742—Esters of oxyacids of phosphorus non-condensed with carbocyclic rings or heterocyclic rings or ring systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Oncology (AREA)
  • Immunology (AREA)
  • Hematology (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Furan Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Catalysts (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
ES91810477T 1990-06-19 1991-06-19 Enantiomeros de derivados de 2-tetrahidrofurano, intermedios para los mismos y su preparacion. Expired - Lifetime ES2076502T3 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US54043890A 1990-06-19 1990-06-19
US64739691A 1991-01-29 1991-01-29

Publications (1)

Publication Number Publication Date
ES2076502T3 true ES2076502T3 (es) 1995-11-01

Family

ID=27066435

Family Applications (1)

Application Number Title Priority Date Filing Date
ES91810477T Expired - Lifetime ES2076502T3 (es) 1990-06-19 1991-06-19 Enantiomeros de derivados de 2-tetrahidrofurano, intermedios para los mismos y su preparacion.

Country Status (21)

Country Link
EP (1) EP0462935B1 (enExample)
JP (1) JP2709330B2 (enExample)
KR (1) KR920000772A (enExample)
AT (1) ATE125261T1 (enExample)
AU (2) AU649681B2 (enExample)
CA (1) CA2044786A1 (enExample)
CS (1) CS185191A3 (enExample)
DE (1) DE69111311T2 (enExample)
DK (1) DK0462935T3 (enExample)
ES (1) ES2076502T3 (enExample)
FI (1) FI912964L (enExample)
GR (1) GR3017437T3 (enExample)
HK (1) HK111996A (enExample)
HU (1) HU210548B (enExample)
IE (1) IE68417B1 (enExample)
IL (1) IL98524A (enExample)
MY (1) MY107022A (enExample)
NZ (1) NZ238573A (enExample)
PL (1) PL164981B1 (enExample)
PT (1) PT97994B (enExample)
TW (1) TW255897B (enExample)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5208352A (en) * 1992-04-02 1993-05-04 Sandoz Ltd. Process for preparing the R- and S-isomers of 2-hydroxy-methyl-2-octadecyloxymethyl-tetrahydrofuran and their use in preparing stereoisomers of pharmacologically active compounds
DE69903381T2 (de) * 1998-07-17 2003-06-18 Fuji Photo Film Co Ltd Photozelle und photoelektrochemische Zelle

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0178261A3 (en) * 1984-10-10 1986-12-30 Sandoz Ag Substituted 2-furanyl or 5-oxo-2-furanyl-alkoxy phosphoryl alkyl cyclimmonium salts
US4601987A (en) * 1985-02-27 1986-07-22 Massachusetts Institute Of Technology Enzymatic production of optical isomers of 2-halopropionic acids
DE3666435D1 (en) * 1985-08-30 1989-11-23 Sandoz Ag Substituted hydroxy-heterocyclyl-alkoxy phosphinyloxy trialkylaminium hydroxide inner salt oxides, processes for their preparation and their use as pharmaceuticals
US4673672A (en) 1985-10-28 1987-06-16 Sandoz Pharmaceuticals Corp. Substituted-[hydroxy(tetrahydro)-5-oxo-(2- and 3-furanyl or 2-thienyl)alkoxyphosphinyloxy]-alkanaminium hydroxide, inner salt oxides
US4868319A (en) * 1987-12-22 1989-09-19 Sandoz Pharm. Corp. Process for the preparation of monoalkylcarbamate group-containing compounds

Also Published As

Publication number Publication date
CA2044786A1 (en) 1991-12-20
AU649681B2 (en) 1994-06-02
IE68417B1 (en) 1996-06-12
KR920000772A (ko) 1992-01-29
DE69111311D1 (de) 1995-08-24
PL290719A1 (en) 1992-07-27
MY107022A (en) 1995-08-30
FI912964A0 (fi) 1991-06-18
IL98524A (en) 1995-12-31
EP0462935B1 (en) 1995-07-19
AU677403B2 (en) 1997-04-24
AU7843991A (en) 1992-01-02
NZ238573A (en) 1993-11-25
DK0462935T3 (da) 1995-11-06
IL98524A0 (en) 1992-07-15
JPH04270276A (ja) 1992-09-25
PT97994B (pt) 1998-11-30
PL164981B1 (pl) 1994-10-31
PT97994A (pt) 1992-03-31
GR3017437T3 (en) 1995-12-31
AU7140794A (en) 1994-11-03
HUT58340A (en) 1992-02-28
HU911882D0 (en) 1991-12-30
JP2709330B2 (ja) 1998-02-04
FI912964A7 (fi) 1991-12-20
IE912081A1 (en) 1992-01-01
CS185191A3 (en) 1992-01-15
HU210548B (en) 1995-05-29
TW255897B (enExample) 1995-09-01
ATE125261T1 (de) 1995-08-15
HK111996A (en) 1996-07-05
DE69111311T2 (de) 1996-03-14
EP0462935A1 (en) 1991-12-27
FI912964L (fi) 1991-12-20

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