ATE125261T1 - 2-tetrahydrofuran-enantiomerderivate, zwischenprodukte davon und ihre herstellung. - Google Patents
2-tetrahydrofuran-enantiomerderivate, zwischenprodukte davon und ihre herstellung.Info
- Publication number
- ATE125261T1 ATE125261T1 AT91810477T AT91810477T ATE125261T1 AT E125261 T1 ATE125261 T1 AT E125261T1 AT 91810477 T AT91810477 T AT 91810477T AT 91810477 T AT91810477 T AT 91810477T AT E125261 T1 ATE125261 T1 AT E125261T1
- Authority
- AT
- Austria
- Prior art keywords
- compound
- formula
- tetrahydrofuran
- enantiomer
- production
- Prior art date
Links
- 239000013067 intermediate product Substances 0.000 title 1
- 150000001875 compounds Chemical class 0.000 abstract 3
- LMBFAGIMSUYTBN-MPZNNTNKSA-N teixobactin Chemical compound C([C@H](C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CO)C(=O)N[C@H](CCC(N)=O)C(=O)N[C@H]([C@@H](C)CC)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CO)C(=O)N[C@H]1C(N[C@@H](C)C(=O)N[C@@H](C[C@@H]2NC(=N)NC2)C(=O)N[C@H](C(=O)O[C@H]1C)[C@@H](C)CC)=O)NC)C1=CC=CC=C1 LMBFAGIMSUYTBN-MPZNNTNKSA-N 0.000 abstract 2
- IXZHWGJCHBDVLV-UHFFFAOYSA-N C(CCC)(=O)O.C(CCC)(=O)O.OCC1(OCCC1)CO Chemical compound C(CCC)(=O)O.C(CCC)(=O)O.OCC1(OCCC1)CO IXZHWGJCHBDVLV-UHFFFAOYSA-N 0.000 abstract 1
- 206010028980 Neoplasm Diseases 0.000 abstract 1
- WYURNTSHIVDZCO-UHFFFAOYSA-N Tetrahydrofuran Chemical group C1CCOC1 WYURNTSHIVDZCO-UHFFFAOYSA-N 0.000 abstract 1
- 229910052799 carbon Inorganic materials 0.000 abstract 1
- 125000004432 carbon atom Chemical group C* 0.000 abstract 1
- 238000010511 deprotection reaction Methods 0.000 abstract 1
- 230000000694 effects Effects 0.000 abstract 1
- 239000000543 intermediate Substances 0.000 abstract 1
- 201000006417 multiple sclerosis Diseases 0.000 abstract 1
- 125000004430 oxygen atom Chemical group O* 0.000 abstract 1
- 230000000144 pharmacologic effect Effects 0.000 abstract 1
- 238000006467 substitution reaction Methods 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/06—Phosphorus compounds without P—C bonds
- C07F9/08—Esters of oxyacids of phosphorus
- C07F9/09—Esters of phosphoric acids
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/02—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
- C07D307/04—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
- C07D307/10—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having no double bonds between ring members or between ring members and non-ring members with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D307/12—Radicals substituted by oxygen atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/02—Antineoplastic agents specific for leukemia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
- C07F9/655—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having oxygen atoms, with or without sulfur, selenium, or tellurium atoms, as the only ring hetero atoms
- C07F9/65515—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having oxygen atoms, with or without sulfur, selenium, or tellurium atoms, as the only ring hetero atoms the oxygen atom being part of a five-membered ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
- C07F9/6564—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having phosphorus atoms, with or without nitrogen, oxygen, sulfur, selenium or tellurium atoms, as ring hetero atoms
- C07F9/6571—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having phosphorus atoms, with or without nitrogen, oxygen, sulfur, selenium or tellurium atoms, as ring hetero atoms having phosphorus and oxygen atoms as the only ring hetero atoms
- C07F9/6574—Esters of oxyacids of phosphorus
- C07F9/65742—Esters of oxyacids of phosphorus non-condensed with carbocyclic rings or heterocyclic rings or ring systems
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biomedical Technology (AREA)
- Immunology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Hematology (AREA)
- Oncology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Furan Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
- Plural Heterocyclic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Catalysts (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US54043890A | 1990-06-19 | 1990-06-19 | |
| US64739691A | 1991-01-29 | 1991-01-29 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE125261T1 true ATE125261T1 (de) | 1995-08-15 |
Family
ID=27066435
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT91810477T ATE125261T1 (de) | 1990-06-19 | 1991-06-19 | 2-tetrahydrofuran-enantiomerderivate, zwischenprodukte davon und ihre herstellung. |
Country Status (21)
| Country | Link |
|---|---|
| EP (1) | EP0462935B1 (de) |
| JP (1) | JP2709330B2 (de) |
| KR (1) | KR920000772A (de) |
| AT (1) | ATE125261T1 (de) |
| AU (2) | AU649681B2 (de) |
| CA (1) | CA2044786A1 (de) |
| CS (1) | CS185191A3 (de) |
| DE (1) | DE69111311T2 (de) |
| DK (1) | DK0462935T3 (de) |
| ES (1) | ES2076502T3 (de) |
| FI (1) | FI912964A (de) |
| GR (1) | GR3017437T3 (de) |
| HK (1) | HK111996A (de) |
| HU (1) | HU210548B (de) |
| IE (1) | IE68417B1 (de) |
| IL (1) | IL98524A (de) |
| MY (1) | MY107022A (de) |
| NZ (1) | NZ238573A (de) |
| PL (1) | PL164981B1 (de) |
| PT (1) | PT97994B (de) |
| TW (1) | TW255897B (de) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5208352A (en) * | 1992-04-02 | 1993-05-04 | Sandoz Ltd. | Process for preparing the R- and S-isomers of 2-hydroxy-methyl-2-octadecyloxymethyl-tetrahydrofuran and their use in preparing stereoisomers of pharmacologically active compounds |
| DE69903381T2 (de) * | 1998-07-17 | 2003-06-18 | Fuji Photo Film Co Ltd | Photozelle und photoelektrochemische Zelle |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0178261A3 (de) * | 1984-10-10 | 1986-12-30 | Sandoz Ag | Substituierte 2-Furanyl- oder -5-Oxo-2-furanyl-alkoxy-phosphorylalkylcyclimmoniumsalze |
| US4601987A (en) * | 1985-02-27 | 1986-07-22 | Massachusetts Institute Of Technology | Enzymatic production of optical isomers of 2-halopropionic acids |
| EP0213082B1 (de) * | 1985-08-30 | 1989-10-18 | Sandoz Ag | Substituierte Hydroxy-heterocyclyl-alkoxy-phosphinyloxy-trialkylaminium-hydroxid-Innersalzoxyde, Verfahren zu ihrer Herstellung und ihre Verwendung als Arzneimittel |
| US4673672A (en) * | 1985-10-28 | 1987-06-16 | Sandoz Pharmaceuticals Corp. | Substituted-[hydroxy(tetrahydro)-5-oxo-(2- and 3-furanyl or 2-thienyl)alkoxyphosphinyloxy]-alkanaminium hydroxide, inner salt oxides |
| US4868319A (en) * | 1987-12-22 | 1989-09-19 | Sandoz Pharm. Corp. | Process for the preparation of monoalkylcarbamate group-containing compounds |
-
1991
- 1991-06-06 HU HU911882A patent/HU210548B/hu not_active IP Right Cessation
- 1991-06-17 IL IL9852491A patent/IL98524A/en not_active IP Right Cessation
- 1991-06-17 CA CA002044786A patent/CA2044786A1/en not_active Abandoned
- 1991-06-17 CS CS911851A patent/CS185191A3/cs unknown
- 1991-06-17 PT PT97994A patent/PT97994B/pt not_active IP Right Cessation
- 1991-06-17 AU AU78439/91A patent/AU649681B2/en not_active Ceased
- 1991-06-17 NZ NZ238573A patent/NZ238573A/en unknown
- 1991-06-18 IE IE208191A patent/IE68417B1/en not_active IP Right Cessation
- 1991-06-18 FI FI912964A patent/FI912964A/fi not_active Application Discontinuation
- 1991-06-18 KR KR1019910010079A patent/KR920000772A/ko not_active Application Discontinuation
- 1991-06-18 MY MYPI91001089A patent/MY107022A/en unknown
- 1991-06-18 JP JP3173245A patent/JP2709330B2/ja not_active Expired - Lifetime
- 1991-06-18 PL PL91290719A patent/PL164981B1/pl unknown
- 1991-06-19 AT AT91810477T patent/ATE125261T1/de not_active IP Right Cessation
- 1991-06-19 DK DK91810477.9T patent/DK0462935T3/da active
- 1991-06-19 ES ES91810477T patent/ES2076502T3/es not_active Expired - Lifetime
- 1991-06-19 DE DE69111311T patent/DE69111311T2/de not_active Expired - Fee Related
- 1991-06-19 EP EP91810477A patent/EP0462935B1/de not_active Expired - Lifetime
- 1991-07-09 TW TW080105309A patent/TW255897B/zh active
-
1994
- 1994-08-23 AU AU71407/94A patent/AU677403B2/en not_active Ceased
-
1995
- 1995-09-18 GR GR950402562T patent/GR3017437T3/el unknown
-
1996
- 1996-06-27 HK HK111996A patent/HK111996A/xx not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| AU7140794A (en) | 1994-11-03 |
| PT97994B (pt) | 1998-11-30 |
| AU677403B2 (en) | 1997-04-24 |
| GR3017437T3 (en) | 1995-12-31 |
| PT97994A (pt) | 1992-03-31 |
| NZ238573A (en) | 1993-11-25 |
| IL98524A (en) | 1995-12-31 |
| PL290719A1 (en) | 1992-07-27 |
| TW255897B (de) | 1995-09-01 |
| FI912964A0 (fi) | 1991-06-18 |
| MY107022A (en) | 1995-08-30 |
| HK111996A (en) | 1996-07-05 |
| EP0462935B1 (de) | 1995-07-19 |
| DE69111311D1 (de) | 1995-08-24 |
| FI912964A (fi) | 1991-12-20 |
| JP2709330B2 (ja) | 1998-02-04 |
| AU7843991A (en) | 1992-01-02 |
| CA2044786A1 (en) | 1991-12-20 |
| IL98524A0 (en) | 1992-07-15 |
| CS185191A3 (en) | 1992-01-15 |
| AU649681B2 (en) | 1994-06-02 |
| PL164981B1 (pl) | 1994-10-31 |
| HUT58340A (en) | 1992-02-28 |
| DK0462935T3 (da) | 1995-11-06 |
| HU210548B (en) | 1995-05-29 |
| HU911882D0 (en) | 1991-12-30 |
| DE69111311T2 (de) | 1996-03-14 |
| EP0462935A1 (de) | 1991-12-27 |
| IE68417B1 (en) | 1996-06-12 |
| ES2076502T3 (es) | 1995-11-01 |
| IE912081A1 (en) | 1992-01-01 |
| KR920000772A (ko) | 1992-01-29 |
| JPH04270276A (ja) | 1992-09-25 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| DE3773660D1 (de) | Morpholinoethylester von mycophenolsaeure und ihre derivate, ihre herstellung und verwendung in pharmazeutische zusammensetzungen. | |
| ATE124695T1 (de) | Kondensierte heterocyclische verbindungen, ihre herstellung und verwendung. | |
| MY108967A (en) | Triazolopyridazine compounds, their production and use | |
| AU652981B2 (en) | Condensed benzoxa ring compound, production thereof, and pharmaceutical composition containing the same | |
| ZA902633B (en) | New sulphonamides derived from benzo-cyclic or benzo heterocyclic acids,their preparation and their application in therapy | |
| BR8902929A (pt) | Artigo vendavel | |
| ATE13178T1 (de) | 2-oxoazetidin-derivate, ihre herstellung und verwendung. | |
| DE3586649D1 (de) | Verwendung von spergualinderivaten zur herstellung von arzneimitteln mit immunodepressiver wirkung. | |
| ATE125261T1 (de) | 2-tetrahydrofuran-enantiomerderivate, zwischenprodukte davon und ihre herstellung. | |
| ES8401926A1 (es) | Un procedimiento para la preparacion de un compuesto de hidroxibencilaminobenceno, dotado de propiedades antiinflamatorias. | |
| ES2100177T3 (es) | Compuestos de cefalosporina y su produccion. | |
| ATE40118T1 (de) | Benzazepinderivate, ihre herstellung und ihre verwendung als arzneimittel. | |
| US4367341A (en) | Antiatherosclerotic 7-substituted methoxyfurochromones | |
| ES479005A1 (es) | Un procedimiento para obtener derivados de quinazolina. | |
| DE3887585D1 (de) | (Aryl oder heteroaromatische methyl)-2,2'-Bi-1H-Imidazole. | |
| DE69828037D1 (de) | Pyrroloindol-derivate und zwischenprodukte zu ihrer herstellung |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| UEP | Publication of translation of european patent specification | ||
| REN | Ceased due to non-payment of the annual fee |