HK111996A - Enantiomers of 2-tetrahydrofuran derivatives intermediates therefor and their preparation - Google Patents
Enantiomers of 2-tetrahydrofuran derivatives intermediates therefor and their preparationInfo
- Publication number
- HK111996A HK111996A HK111996A HK111996A HK111996A HK 111996 A HK111996 A HK 111996A HK 111996 A HK111996 A HK 111996A HK 111996 A HK111996 A HK 111996A HK 111996 A HK111996 A HK 111996A
- Authority
- HK
- Hong Kong
- Prior art keywords
- compound
- formula
- enantiomers
- preparation
- tetrahydrofuran
- Prior art date
Links
- 239000000543 intermediate Substances 0.000 title abstract 2
- HBAQYPYDRFILMT-UHFFFAOYSA-N 8-[3-(1-cyclopropylpyrazol-4-yl)-1H-pyrazolo[4,3-d]pyrimidin-5-yl]-3-methyl-3,8-diazabicyclo[3.2.1]octan-2-one Chemical class C1(CC1)N1N=CC(=C1)C1=NNC2=C1N=C(N=C2)N1C2C(N(CC1CC2)C)=O HBAQYPYDRFILMT-UHFFFAOYSA-N 0.000 title 1
- 150000001875 compounds Chemical class 0.000 abstract 3
- LMBFAGIMSUYTBN-MPZNNTNKSA-N teixobactin Chemical compound C([C@H](C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CO)C(=O)N[C@H](CCC(N)=O)C(=O)N[C@H]([C@@H](C)CC)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CO)C(=O)N[C@H]1C(N[C@@H](C)C(=O)N[C@@H](C[C@@H]2NC(=N)NC2)C(=O)N[C@H](C(=O)O[C@H]1C)[C@@H](C)CC)=O)NC)C1=CC=CC=C1 LMBFAGIMSUYTBN-MPZNNTNKSA-N 0.000 abstract 2
- IXZHWGJCHBDVLV-UHFFFAOYSA-N C(CCC)(=O)O.C(CCC)(=O)O.OCC1(OCCC1)CO Chemical compound C(CCC)(=O)O.C(CCC)(=O)O.OCC1(OCCC1)CO IXZHWGJCHBDVLV-UHFFFAOYSA-N 0.000 abstract 1
- 206010028980 Neoplasm Diseases 0.000 abstract 1
- WYURNTSHIVDZCO-UHFFFAOYSA-N Tetrahydrofuran Chemical group C1CCOC1 WYURNTSHIVDZCO-UHFFFAOYSA-N 0.000 abstract 1
- 229910052799 carbon Inorganic materials 0.000 abstract 1
- 125000004432 carbon atom Chemical group C* 0.000 abstract 1
- 238000010511 deprotection reaction Methods 0.000 abstract 1
- 230000000694 effects Effects 0.000 abstract 1
- 201000006417 multiple sclerosis Diseases 0.000 abstract 1
- 125000004430 oxygen atom Chemical group O* 0.000 abstract 1
- 230000000144 pharmacologic effect Effects 0.000 abstract 1
- 238000006467 substitution reaction Methods 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/06—Phosphorus compounds without P—C bonds
- C07F9/08—Esters of oxyacids of phosphorus
- C07F9/09—Esters of phosphoric acids
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/02—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
- C07D307/04—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
- C07D307/10—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having no double bonds between ring members or between ring members and non-ring members with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D307/12—Radicals substituted by oxygen atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/02—Antineoplastic agents specific for leukemia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
- C07F9/655—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having oxygen atoms, with or without sulfur, selenium, or tellurium atoms, as the only ring hetero atoms
- C07F9/65515—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having oxygen atoms, with or without sulfur, selenium, or tellurium atoms, as the only ring hetero atoms the oxygen atom being part of a five-membered ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
- C07F9/6564—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having phosphorus atoms, with or without nitrogen, oxygen, sulfur, selenium or tellurium atoms, as ring hetero atoms
- C07F9/6571—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having phosphorus atoms, with or without nitrogen, oxygen, sulfur, selenium or tellurium atoms, as ring hetero atoms having phosphorus and oxygen atoms as the only ring hetero atoms
- C07F9/6574—Esters of oxyacids of phosphorus
- C07F9/65742—Esters of oxyacids of phosphorus non-condensed with carbocyclic rings or heterocyclic rings or ring systems
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- Biochemistry (AREA)
- Molecular Biology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Oncology (AREA)
- Immunology (AREA)
- Hematology (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Furan Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Plural Heterocyclic Compounds (AREA)
- Catalysts (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US54043890A | 1990-06-19 | 1990-06-19 | |
| US64739691A | 1991-01-29 | 1991-01-29 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| HK111996A true HK111996A (en) | 1996-07-05 |
Family
ID=27066435
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| HK111996A HK111996A (en) | 1990-06-19 | 1996-06-27 | Enantiomers of 2-tetrahydrofuran derivatives intermediates therefor and their preparation |
Country Status (21)
| Country | Link |
|---|---|
| EP (1) | EP0462935B1 (de) |
| JP (1) | JP2709330B2 (de) |
| KR (1) | KR920000772A (de) |
| AT (1) | ATE125261T1 (de) |
| AU (2) | AU649681B2 (de) |
| CA (1) | CA2044786A1 (de) |
| CS (1) | CS185191A3 (de) |
| DE (1) | DE69111311T2 (de) |
| DK (1) | DK0462935T3 (de) |
| ES (1) | ES2076502T3 (de) |
| FI (1) | FI912964A (de) |
| GR (1) | GR3017437T3 (de) |
| HK (1) | HK111996A (de) |
| HU (1) | HU210548B (de) |
| IE (1) | IE68417B1 (de) |
| IL (1) | IL98524A (de) |
| MY (1) | MY107022A (de) |
| NZ (1) | NZ238573A (de) |
| PL (1) | PL164981B1 (de) |
| PT (1) | PT97994B (de) |
| TW (1) | TW255897B (de) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5208352A (en) * | 1992-04-02 | 1993-05-04 | Sandoz Ltd. | Process for preparing the R- and S-isomers of 2-hydroxy-methyl-2-octadecyloxymethyl-tetrahydrofuran and their use in preparing stereoisomers of pharmacologically active compounds |
| DE69903381T2 (de) * | 1998-07-17 | 2003-06-18 | Fuji Photo Film Co Ltd | Photozelle und photoelektrochemische Zelle |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0178261A3 (de) * | 1984-10-10 | 1986-12-30 | Sandoz Ag | Substituierte 2-Furanyl- oder -5-Oxo-2-furanyl-alkoxy-phosphorylalkylcyclimmoniumsalze |
| US4601987A (en) * | 1985-02-27 | 1986-07-22 | Massachusetts Institute Of Technology | Enzymatic production of optical isomers of 2-halopropionic acids |
| EP0213082B1 (de) * | 1985-08-30 | 1989-10-18 | Sandoz Ag | Substituierte Hydroxy-heterocyclyl-alkoxy-phosphinyloxy-trialkylaminium-hydroxid-Innersalzoxyde, Verfahren zu ihrer Herstellung und ihre Verwendung als Arzneimittel |
| US4673672A (en) | 1985-10-28 | 1987-06-16 | Sandoz Pharmaceuticals Corp. | Substituted-[hydroxy(tetrahydro)-5-oxo-(2- and 3-furanyl or 2-thienyl)alkoxyphosphinyloxy]-alkanaminium hydroxide, inner salt oxides |
| US4868319A (en) * | 1987-12-22 | 1989-09-19 | Sandoz Pharm. Corp. | Process for the preparation of monoalkylcarbamate group-containing compounds |
-
1991
- 1991-06-06 HU HU911882A patent/HU210548B/hu not_active IP Right Cessation
- 1991-06-17 NZ NZ238573A patent/NZ238573A/en unknown
- 1991-06-17 AU AU78439/91A patent/AU649681B2/en not_active Ceased
- 1991-06-17 CA CA002044786A patent/CA2044786A1/en not_active Abandoned
- 1991-06-17 PT PT97994A patent/PT97994B/pt not_active IP Right Cessation
- 1991-06-17 CS CS911851A patent/CS185191A3/cs unknown
- 1991-06-17 IL IL9852491A patent/IL98524A/en not_active IP Right Cessation
- 1991-06-18 PL PL91290719A patent/PL164981B1/pl unknown
- 1991-06-18 IE IE208191A patent/IE68417B1/en not_active IP Right Cessation
- 1991-06-18 KR KR1019910010079A patent/KR920000772A/ko not_active Application Discontinuation
- 1991-06-18 JP JP3173245A patent/JP2709330B2/ja not_active Expired - Lifetime
- 1991-06-18 MY MYPI91001089A patent/MY107022A/en unknown
- 1991-06-18 FI FI912964A patent/FI912964A/fi not_active Application Discontinuation
- 1991-06-19 AT AT91810477T patent/ATE125261T1/de not_active IP Right Cessation
- 1991-06-19 DK DK91810477.9T patent/DK0462935T3/da active
- 1991-06-19 DE DE69111311T patent/DE69111311T2/de not_active Expired - Fee Related
- 1991-06-19 ES ES91810477T patent/ES2076502T3/es not_active Expired - Lifetime
- 1991-06-19 EP EP91810477A patent/EP0462935B1/de not_active Expired - Lifetime
- 1991-07-09 TW TW080105309A patent/TW255897B/zh active
-
1994
- 1994-08-23 AU AU71407/94A patent/AU677403B2/en not_active Ceased
-
1995
- 1995-09-18 GR GR950402562T patent/GR3017437T3/el unknown
-
1996
- 1996-06-27 HK HK111996A patent/HK111996A/xx not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| TW255897B (de) | 1995-09-01 |
| KR920000772A (ko) | 1992-01-29 |
| FI912964A0 (fi) | 1991-06-18 |
| IE912081A1 (en) | 1992-01-01 |
| CA2044786A1 (en) | 1991-12-20 |
| HU210548B (en) | 1995-05-29 |
| AU677403B2 (en) | 1997-04-24 |
| IL98524A (en) | 1995-12-31 |
| PT97994A (pt) | 1992-03-31 |
| ATE125261T1 (de) | 1995-08-15 |
| HUT58340A (en) | 1992-02-28 |
| GR3017437T3 (en) | 1995-12-31 |
| NZ238573A (en) | 1993-11-25 |
| CS185191A3 (en) | 1992-01-15 |
| DK0462935T3 (da) | 1995-11-06 |
| FI912964A (fi) | 1991-12-20 |
| AU7843991A (en) | 1992-01-02 |
| AU7140794A (en) | 1994-11-03 |
| DE69111311D1 (de) | 1995-08-24 |
| JP2709330B2 (ja) | 1998-02-04 |
| EP0462935B1 (de) | 1995-07-19 |
| ES2076502T3 (es) | 1995-11-01 |
| PT97994B (pt) | 1998-11-30 |
| AU649681B2 (en) | 1994-06-02 |
| JPH04270276A (ja) | 1992-09-25 |
| IE68417B1 (en) | 1996-06-12 |
| PL164981B1 (pl) | 1994-10-31 |
| HU911882D0 (en) | 1991-12-30 |
| PL290719A1 (en) | 1992-07-27 |
| IL98524A0 (en) | 1992-07-15 |
| DE69111311T2 (de) | 1996-03-14 |
| EP0462935A1 (de) | 1991-12-27 |
| MY107022A (en) | 1995-08-30 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PC | Patent ceased (i.e. patent has lapsed due to the failure to pay the renewal fee) |