ES2074968A1 - Nuevas cepas de pseudomonas aeruginosa atenuadas. - Google Patents
Nuevas cepas de pseudomonas aeruginosa atenuadas.Info
- Publication number
- ES2074968A1 ES2074968A1 ES09550003A ES9550003A ES2074968A1 ES 2074968 A1 ES2074968 A1 ES 2074968A1 ES 09550003 A ES09550003 A ES 09550003A ES 9550003 A ES9550003 A ES 9550003A ES 2074968 A1 ES2074968 A1 ES 2074968A1
- Authority
- ES
- Spain
- Prior art keywords
- cfcpa
- kccm
- pseudomonas aeruginosa
- cell wall
- strains
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 241000589517 Pseudomonas aeruginosa Species 0.000 title abstract 4
- 230000002238 attenuated effect Effects 0.000 title abstract 4
- 210000002421 cell wall Anatomy 0.000 abstract 4
- 235000018102 proteins Nutrition 0.000 abstract 3
- 102000004169 proteins and genes Human genes 0.000 abstract 3
- 108090000623 proteins and genes Proteins 0.000 abstract 3
- 208000032536 Pseudomonas Infections Diseases 0.000 abstract 2
- 239000003814 drug Substances 0.000 abstract 2
- 229940124597 therapeutic agent Drugs 0.000 abstract 2
- 229960005486 vaccine Drugs 0.000 abstract 2
- 108060003951 Immunoglobulin Proteins 0.000 abstract 1
- 238000010171 animal model Methods 0.000 abstract 1
- 230000015572 biosynthetic process Effects 0.000 abstract 1
- 238000002474 experimental method Methods 0.000 abstract 1
- 230000003053 immunization Effects 0.000 abstract 1
- 238000002649 immunization Methods 0.000 abstract 1
- 102000018358 immunoglobulin Human genes 0.000 abstract 1
- 230000001939 inductive effect Effects 0.000 abstract 1
- 230000001717 pathogenic effect Effects 0.000 abstract 1
- 235000004252 protein component Nutrition 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
- C07K14/21—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Pseudomonadaceae (F)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/02—Bacterial antigens
- A61K39/104—Pseudomonadales, e.g. Pseudomonas
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/12—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from bacteria
- C07K16/1203—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from bacteria from Gram-negative bacteria
- C07K16/1214—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from bacteria from Gram-negative bacteria from Pseudomonadaceae (F)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Genetics & Genomics (AREA)
- Biophysics (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biochemistry (AREA)
- Immunology (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Gastroenterology & Hepatology (AREA)
- Microbiology (AREA)
- Mycology (AREA)
- Epidemiology (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Peptides Or Proteins (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
Abstract
NUEVAS CEPAS DE PSEUDOMONAS AERUGINOSA ATENUADAS Y VACUNAS PARA LA PROFILAXIS CONTRA LA INFECCION DE PSEUDOMONAS AERUGINOSA QUE COMPRENDE UNA MEZCLA DE PROTEINAS DE LA PARED CELULAR DERIVADAS, AL MENOS, DE UNA NUEVA CEPA DE PSEUDOMONAS AERUGINOSA ATENUADA, Y UN PROCEDIMIENTO PARA PREPARAR DICHA VACUNA QUE COMPRENDE: RECOGER PSEUDOMONAS AERUGINOSA DE PACIENTES INFECTADOS CON LA MISMA; SELECCIONAR Y AISLAR AL MENOS UNA ESPECIE EN ESTADO PURO; INCUBAR DICHAS ESPECIES EN UN PRIMER MEDIO DE CULTIVO; ATENUAR CADA CEPA INCUBADA Y SELECCIONAR LA CEPA MAS ATENUADA; INCUBAR CADA CEPA ATENUADA EN UN SEGUNDO MEDIO DE CULTIVO; SEPARAR LA CEPA DEL MEDIO DE CULTIVO; TRATAR LA CEPA CON DISOLVENTE ORGANICO; EXTRAER LAS PROTEINAS DE LA PARED CELULAR; SOMETER LAS PROTEINAS A ULTRAFILTRACION; ULTRACENTRIFUGAR LAS PROTEINAS, RECUPERAR LAS PROTEINAS EN UN ESTADO PURO; Y PREPARAR UNA VACUNA UTILIZANDO LAS PROTEINAS DE LA PARED CELULAR SELECCIONADAS COMO UNA SUSTANCIA ANTIGENICA. (*) 13 (DAL HYUN KIM Y 14) YOUNG GI KIM.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
KR1019930010281A KR970001710B1 (ko) | 1993-06-07 | 1993-06-07 | 녹농균 감염증 치료제 및 그의 제조방법 |
KR1019930010273A KR960014620B1 (ko) | 1993-06-07 | 1993-06-07 | 신규한 약독화 녹농균 및 그를 이용한 녹농균 감염 예방 백신 |
Publications (2)
Publication Number | Publication Date |
---|---|
ES2074968A1 true ES2074968A1 (es) | 1995-09-16 |
ES2074968B1 ES2074968B1 (es) | 1996-05-01 |
Family
ID=26629705
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES09550003A Expired - Fee Related ES2074968B1 (es) | 1993-06-07 | 1994-06-02 | Nuevas cepas de pseudomonas aeruginosa atenuadas. |
Country Status (16)
Country | Link |
---|---|
EP (1) | EP0702564B1 (es) |
JP (1) | JP2911603B2 (es) |
CN (1) | CN1112356A (es) |
AT (1) | AT408445B (es) |
AU (1) | AU676575B2 (es) |
CA (1) | CA2141871C (es) |
CH (1) | CH687233A5 (es) |
DE (3) | DE4493997C2 (es) |
ES (1) | ES2074968B1 (es) |
GB (1) | GB2285925B (es) |
NL (1) | NL194910C (es) |
NO (1) | NO317148B1 (es) |
RU (1) | RU2155226C2 (es) |
SE (1) | SE507114C2 (es) |
TW (1) | TW403655B (es) |
WO (1) | WO1994028928A1 (es) |
Families Citing this family (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN1086588C (zh) * | 1995-12-07 | 2002-06-26 | 余国华 | 假单胞菌活性蛋白及其生产方法 |
CN1328371C (zh) * | 2005-09-01 | 2007-07-25 | 北京未名凯拓农业生物技术有限公司 | 一株铜绿假单胞菌及其培养方法与应用 |
CN102534029A (zh) * | 2012-02-14 | 2012-07-04 | 上海中优医药高科技有限公司 | MRSA中QacB基因的检测引物及其检测方法 |
CN102534027A (zh) * | 2012-02-14 | 2012-07-04 | 上海中优医药高科技有限公司 | MDRPA中QacEΔ1基因的检测引物及其检测方法 |
IT201600091033A1 (it) * | 2016-09-08 | 2018-03-08 | Bioimmunizer Sagl | Ceppi di batteri probiotici appartenenti al genere Bifidobacterium e loro estratti di cellule probiotiche (ECP) aventi proprietà immunostimolanti. |
CN109401992B (zh) * | 2017-08-18 | 2021-07-23 | 黑龙江省科学院微生物研究所 | 一株高产内毒素蛋白的铜绿假单胞菌及其应用 |
CN110724647B (zh) * | 2018-07-17 | 2022-11-04 | 黑龙江省科学院微生物研究所 | 一株所产内毒素蛋白对7种血清型菌株具有免疫保护作用的铜绿假单胞菌及其应用 |
US20220378902A1 (en) * | 2019-08-22 | 2022-12-01 | Sichuan University | Bacterial membrane vesicles, and separation and preparation system and method therefor |
CN114763544A (zh) * | 2021-01-15 | 2022-07-19 | 黑龙江省科学院微生物研究所 | 一种铜绿假单胞菌高产蛋白菌株的生物诱变方法 |
Citations (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3928565A (en) * | 1971-10-19 | 1975-12-23 | Yuzuru Homma | Pharmaceutical preparation of pseudomonas aeruginosa bacterial component possessing anti-tumor and anti-infection properties |
US3987164A (en) * | 1970-10-20 | 1976-10-19 | Yuzuru Homma | Method for prevention of pseudomonas aeruginosa infections |
EP0357024A2 (de) * | 1988-09-01 | 1990-03-07 | BEHRINGWERKE Aktiengesellschaft | Lipoprotein I (OMPI) von Pseudomonas aeruginosa |
Family Cites Families (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS5612435B1 (es) * | 1971-03-29 | 1981-03-20 |
-
1994
- 1994-06-02 DE DE4493997A patent/DE4493997C2/de not_active Expired - Fee Related
- 1994-06-02 AU AU68571/94A patent/AU676575B2/en not_active Ceased
- 1994-06-02 CA CA002141871A patent/CA2141871C/en not_active Expired - Fee Related
- 1994-06-02 CN CN94190491A patent/CN1112356A/zh active Pending
- 1994-06-02 EP EP94917176A patent/EP0702564B1/en not_active Expired - Lifetime
- 1994-06-02 CH CH00454/95A patent/CH687233A5/de not_active IP Right Cessation
- 1994-06-02 AT AT0900694A patent/AT408445B/de not_active IP Right Cessation
- 1994-06-02 ES ES09550003A patent/ES2074968B1/es not_active Expired - Fee Related
- 1994-06-02 JP JP7501593A patent/JP2911603B2/ja not_active Expired - Fee Related
- 1994-06-02 RU RU95113158/13A patent/RU2155226C2/ru not_active IP Right Cessation
- 1994-06-02 NL NL9420005A patent/NL194910C/nl not_active IP Right Cessation
- 1994-06-02 GB GB9502373A patent/GB2285925B/en not_active Expired - Fee Related
- 1994-06-02 WO PCT/KR1994/000062 patent/WO1994028928A1/en active IP Right Grant
- 1994-06-02 DE DE4447677A patent/DE4447677C2/de not_active Expired - Fee Related
- 1994-06-02 DE DE4493997T patent/DE4493997T1/de active Pending
- 1994-06-04 TW TW083105105A patent/TW403655B/zh not_active IP Right Cessation
-
1995
- 1995-02-06 NO NO19950421A patent/NO317148B1/no not_active IP Right Cessation
- 1995-02-06 SE SE9500418A patent/SE507114C2/sv not_active IP Right Cessation
Patent Citations (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3987164A (en) * | 1970-10-20 | 1976-10-19 | Yuzuru Homma | Method for prevention of pseudomonas aeruginosa infections |
US3928565A (en) * | 1971-10-19 | 1975-12-23 | Yuzuru Homma | Pharmaceutical preparation of pseudomonas aeruginosa bacterial component possessing anti-tumor and anti-infection properties |
EP0357024A2 (de) * | 1988-09-01 | 1990-03-07 | BEHRINGWERKE Aktiengesellschaft | Lipoprotein I (OMPI) von Pseudomonas aeruginosa |
Also Published As
Publication number | Publication date |
---|---|
GB9502373D0 (en) | 1995-03-29 |
NL194910B (nl) | 2003-03-03 |
WO1994028928A1 (en) | 1994-12-22 |
JP2911603B2 (ja) | 1999-06-23 |
GB2285925A (en) | 1995-08-02 |
DE4447677C2 (de) | 1998-07-23 |
ES2074968B1 (es) | 1996-05-01 |
AT408445B (de) | 2001-11-26 |
NO950421D0 (no) | 1995-02-06 |
CH687233A5 (de) | 1996-10-31 |
CN1112356A (zh) | 1995-11-22 |
SE9500418D0 (sv) | 1995-02-06 |
NO950421L (no) | 1995-04-07 |
NL9420005A (nl) | 1995-06-01 |
ATA900694A (de) | 2001-04-15 |
EP0702564B1 (en) | 2000-03-01 |
CA2141871A1 (en) | 1994-12-22 |
NL194910C (nl) | 2003-07-04 |
SE507114C2 (sv) | 1998-03-30 |
TW403655B (en) | 2000-09-01 |
JPH09501826A (ja) | 1997-02-25 |
DE4493997C2 (de) | 1997-07-17 |
AU676575B2 (en) | 1997-03-13 |
GB2285925B (en) | 1997-04-09 |
NO317148B1 (no) | 2004-08-30 |
EP0702564A1 (en) | 1996-03-27 |
AU6857194A (en) | 1995-01-03 |
DE4493997T1 (de) | 1995-10-05 |
RU2155226C2 (ru) | 2000-08-27 |
CA2141871C (en) | 1999-05-11 |
SE9500418L (sv) | 1995-04-07 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
FD2A | Announcement of lapse in spain |
Effective date: 20180806 |