ES2074968A1 - Nuevas cepas de pseudomonas aeruginosa atenuadas. - Google Patents

Nuevas cepas de pseudomonas aeruginosa atenuadas.

Info

Publication number
ES2074968A1
ES2074968A1 ES09550003A ES9550003A ES2074968A1 ES 2074968 A1 ES2074968 A1 ES 2074968A1 ES 09550003 A ES09550003 A ES 09550003A ES 9550003 A ES9550003 A ES 9550003A ES 2074968 A1 ES2074968 A1 ES 2074968A1
Authority
ES
Spain
Prior art keywords
cfcpa
kccm
pseudomonas aeruginosa
cell wall
strains
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
ES09550003A
Other languages
English (en)
Other versions
ES2074968B1 (es
Inventor
Hyun Su Kim
Wan Je Park
Moo Sang Moon
Wang Don Yoo
Kap Soo Noh
Dong Eok Lee
Suk Hoon Ha
Ree An Yoo
Nam Joong Lee
Yang Je Cho
Sun Pyo Hong
Je Hak Kim
Dal Hyun Kim
Young Gi Kim
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Cheil Foods and Chemicals Inc
Original Assignee
Cheil Foods and Chemicals Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from KR1019930010281A external-priority patent/KR970001710B1/ko
Priority claimed from KR1019930010273A external-priority patent/KR960014620B1/ko
Application filed by Cheil Foods and Chemicals Inc filed Critical Cheil Foods and Chemicals Inc
Publication of ES2074968A1 publication Critical patent/ES2074968A1/es
Application granted granted Critical
Publication of ES2074968B1 publication Critical patent/ES2074968B1/es
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/21—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Pseudomonadaceae (F)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/02—Bacterial antigens
    • A61K39/104—Pseudomonadales, e.g. Pseudomonas
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/12—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from bacteria
    • C07K16/1203—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from bacteria from Gram-negative bacteria
    • C07K16/1214—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from bacteria from Gram-negative bacteria from Pseudomonadaceae (F)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Biochemistry (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Immunology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Epidemiology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Peptides Or Proteins (AREA)

Abstract

NUEVAS CEPAS DE PSEUDOMONAS AERUGINOSA ATENUADAS Y VACUNAS PARA LA PROFILAXIS CONTRA LA INFECCION DE PSEUDOMONAS AERUGINOSA QUE COMPRENDE UNA MEZCLA DE PROTEINAS DE LA PARED CELULAR DERIVADAS, AL MENOS, DE UNA NUEVA CEPA DE PSEUDOMONAS AERUGINOSA ATENUADA, Y UN PROCEDIMIENTO PARA PREPARAR DICHA VACUNA QUE COMPRENDE: RECOGER PSEUDOMONAS AERUGINOSA DE PACIENTES INFECTADOS CON LA MISMA; SELECCIONAR Y AISLAR AL MENOS UNA ESPECIE EN ESTADO PURO; INCUBAR DICHAS ESPECIES EN UN PRIMER MEDIO DE CULTIVO; ATENUAR CADA CEPA INCUBADA Y SELECCIONAR LA CEPA MAS ATENUADA; INCUBAR CADA CEPA ATENUADA EN UN SEGUNDO MEDIO DE CULTIVO; SEPARAR LA CEPA DEL MEDIO DE CULTIVO; TRATAR LA CEPA CON DISOLVENTE ORGANICO; EXTRAER LAS PROTEINAS DE LA PARED CELULAR; SOMETER LAS PROTEINAS A ULTRAFILTRACION; ULTRACENTRIFUGAR LAS PROTEINAS, RECUPERAR LAS PROTEINAS EN UN ESTADO PURO; Y PREPARAR UNA VACUNA UTILIZANDO LAS PROTEINAS DE LA PARED CELULAR SELECCIONADAS COMO UNA SUSTANCIA ANTIGENICA. (*) 13 (DAL HYUN KIM Y 14) YOUNG GI KIM.
ES09550003A 1993-06-07 1994-06-02 Nuevas cepas de pseudomonas aeruginosa atenuadas. Expired - Fee Related ES2074968B1 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
KR1019930010281A KR970001710B1 (ko) 1993-06-07 1993-06-07 녹농균 감염증 치료제 및 그의 제조방법
KR1019930010273A KR960014620B1 (ko) 1993-06-07 1993-06-07 신규한 약독화 녹농균 및 그를 이용한 녹농균 감염 예방 백신

Publications (2)

Publication Number Publication Date
ES2074968A1 true ES2074968A1 (es) 1995-09-16
ES2074968B1 ES2074968B1 (es) 1996-05-01

Family

ID=26629705

Family Applications (1)

Application Number Title Priority Date Filing Date
ES09550003A Expired - Fee Related ES2074968B1 (es) 1993-06-07 1994-06-02 Nuevas cepas de pseudomonas aeruginosa atenuadas.

Country Status (16)

Country Link
EP (1) EP0702564B1 (es)
JP (1) JP2911603B2 (es)
CN (1) CN1112356A (es)
AT (1) AT408445B (es)
AU (1) AU676575B2 (es)
CA (1) CA2141871C (es)
CH (1) CH687233A5 (es)
DE (3) DE4493997C2 (es)
ES (1) ES2074968B1 (es)
GB (1) GB2285925B (es)
NL (1) NL194910C (es)
NO (1) NO317148B1 (es)
RU (1) RU2155226C2 (es)
SE (1) SE507114C2 (es)
TW (1) TW403655B (es)
WO (1) WO1994028928A1 (es)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1086588C (zh) * 1995-12-07 2002-06-26 余国华 假单胞菌活性蛋白及其生产方法
CN1328371C (zh) * 2005-09-01 2007-07-25 北京未名凯拓农业生物技术有限公司 一株铜绿假单胞菌及其培养方法与应用
CN102534029A (zh) * 2012-02-14 2012-07-04 上海中优医药高科技有限公司 MRSA中QacB基因的检测引物及其检测方法
CN102534027A (zh) * 2012-02-14 2012-07-04 上海中优医药高科技有限公司 MDRPA中QacEΔ1基因的检测引物及其检测方法
IT201600091033A1 (it) * 2016-09-08 2018-03-08 Bioimmunizer Sagl Ceppi di batteri probiotici appartenenti al genere Bifidobacterium e loro estratti di cellule probiotiche (ECP) aventi proprietà immunostimolanti.
CN109401992B (zh) * 2017-08-18 2021-07-23 黑龙江省科学院微生物研究所 一株高产内毒素蛋白的铜绿假单胞菌及其应用
CN110724647B (zh) * 2018-07-17 2022-11-04 黑龙江省科学院微生物研究所 一株所产内毒素蛋白对7种血清型菌株具有免疫保护作用的铜绿假单胞菌及其应用
US20220378902A1 (en) * 2019-08-22 2022-12-01 Sichuan University Bacterial membrane vesicles, and separation and preparation system and method therefor
CN114763544A (zh) * 2021-01-15 2022-07-19 黑龙江省科学院微生物研究所 一种铜绿假单胞菌高产蛋白菌株的生物诱变方法

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3928565A (en) * 1971-10-19 1975-12-23 Yuzuru Homma Pharmaceutical preparation of pseudomonas aeruginosa bacterial component possessing anti-tumor and anti-infection properties
US3987164A (en) * 1970-10-20 1976-10-19 Yuzuru Homma Method for prevention of pseudomonas aeruginosa infections
EP0357024A2 (de) * 1988-09-01 1990-03-07 BEHRINGWERKE Aktiengesellschaft Lipoprotein I (OMPI) von Pseudomonas aeruginosa

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5612435B1 (es) * 1971-03-29 1981-03-20

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3987164A (en) * 1970-10-20 1976-10-19 Yuzuru Homma Method for prevention of pseudomonas aeruginosa infections
US3928565A (en) * 1971-10-19 1975-12-23 Yuzuru Homma Pharmaceutical preparation of pseudomonas aeruginosa bacterial component possessing anti-tumor and anti-infection properties
EP0357024A2 (de) * 1988-09-01 1990-03-07 BEHRINGWERKE Aktiengesellschaft Lipoprotein I (OMPI) von Pseudomonas aeruginosa

Also Published As

Publication number Publication date
GB9502373D0 (en) 1995-03-29
NL194910B (nl) 2003-03-03
WO1994028928A1 (en) 1994-12-22
JP2911603B2 (ja) 1999-06-23
GB2285925A (en) 1995-08-02
DE4447677C2 (de) 1998-07-23
ES2074968B1 (es) 1996-05-01
AT408445B (de) 2001-11-26
NO950421D0 (no) 1995-02-06
CH687233A5 (de) 1996-10-31
CN1112356A (zh) 1995-11-22
SE9500418D0 (sv) 1995-02-06
NO950421L (no) 1995-04-07
NL9420005A (nl) 1995-06-01
ATA900694A (de) 2001-04-15
EP0702564B1 (en) 2000-03-01
CA2141871A1 (en) 1994-12-22
NL194910C (nl) 2003-07-04
SE507114C2 (sv) 1998-03-30
TW403655B (en) 2000-09-01
JPH09501826A (ja) 1997-02-25
DE4493997C2 (de) 1997-07-17
AU676575B2 (en) 1997-03-13
GB2285925B (en) 1997-04-09
NO317148B1 (no) 2004-08-30
EP0702564A1 (en) 1996-03-27
AU6857194A (en) 1995-01-03
DE4493997T1 (de) 1995-10-05
RU2155226C2 (ru) 2000-08-27
CA2141871C (en) 1999-05-11
SE9500418L (sv) 1995-04-07

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Effective date: 20180806