ES2059485T3 - Derivados de 2-amino-1,2,3,4-tetrahidroisoquinolina, procedimiento de su preparacion y su aplicacion como medicamento. - Google Patents

Derivados de 2-amino-1,2,3,4-tetrahidroisoquinolina, procedimiento de su preparacion y su aplicacion como medicamento.

Info

Publication number
ES2059485T3
ES2059485T3 ES88121900T ES88121900T ES2059485T3 ES 2059485 T3 ES2059485 T3 ES 2059485T3 ES 88121900 T ES88121900 T ES 88121900T ES 88121900 T ES88121900 T ES 88121900T ES 2059485 T3 ES2059485 T3 ES 2059485T3
Authority
ES
Spain
Prior art keywords
tetrahydroisokinoline
amino
procedure
derivatives
preparation
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES88121900T
Other languages
English (en)
Inventor
Endre Dipl-Ing Chem Palosi
Dezso Dr Dipl-Ing Ch Korbonits
Erzsebet Dipl-Ing Chem Molnar
Ida Dipl-Ing Chem Szvoboda
Laszlo Dr Harsing
Gyorgy Dr Simon
Vera Dr Gergely
Peter Dr Kormoczi
Sandor Dr Virag
Katalin Dipl-Ing Che Marmarosi
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Chinoin Private Co Ltd
Original Assignee
Chinoin Gyogyszer es Vegyeszeti Termekek Gyara Zrt
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Chinoin Gyogyszer es Vegyeszeti Termekek Gyara Zrt filed Critical Chinoin Gyogyszer es Vegyeszeti Termekek Gyara Zrt
Application granted granted Critical
Publication of ES2059485T3 publication Critical patent/ES2059485T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D217/00—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
    • C07D217/02—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with only hydrogen atoms or radicals containing only carbon and hydrogen atoms, directly attached to carbon atoms of the nitrogen-containing ring; Alkylene-bis-isoquinolines
    • C07D217/08—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with only hydrogen atoms or radicals containing only carbon and hydrogen atoms, directly attached to carbon atoms of the nitrogen-containing ring; Alkylene-bis-isoquinolines with a hetero atom directly attached to the ring nitrogen atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/10—Antioedematous agents; Diuretics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/02—Non-specific cardiovascular stimulants, e.g. drugs for syncope, antihypotensives
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Cardiology (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Other In-Based Heterocyclic Compounds (AREA)

Abstract

LA PATENTE AFECTA A NUEVOS DERIVADOS DE 2 - AMINO - 1,2,3,4 TETRAHIDROISOQUINOLINA DE FORMULA GENERAL I, DONDE R ES HIDROGENO O CLORO, R1 Y R2 SON HIDROGENO, METOXI O ETOXI Y R3 Y R4 SON HIDROGENO O METILO. LOS COMPUESTOS SE PUEDEN OBTENER POR UN PROCEDIMIENTO EN SI YA CONOCIDO Y POSEEN EFECTOS DIURETICOS, SALURETICOS Y REBAJADORES DE LA PRESION SANGUINEA. ADEMAS SE CITAN LOS MEDIOS FARMACEUTICOS CORRESPONDIENTES Y SU OBTENCION.
ES88121900T 1987-12-30 1988-12-30 Derivados de 2-amino-1,2,3,4-tetrahidroisoquinolina, procedimiento de su preparacion y su aplicacion como medicamento. Expired - Lifetime ES2059485T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
HU876132A HU198458B (en) 1987-12-30 1987-12-30 Process for producing 2-aminoisoquinoline derivatives and pharmaceutical compositions comprising these compounds

Publications (1)

Publication Number Publication Date
ES2059485T3 true ES2059485T3 (es) 1994-11-16

Family

ID=10971251

Family Applications (1)

Application Number Title Priority Date Filing Date
ES88121900T Expired - Lifetime ES2059485T3 (es) 1987-12-30 1988-12-30 Derivados de 2-amino-1,2,3,4-tetrahidroisoquinolina, procedimiento de su preparacion y su aplicacion como medicamento.

Country Status (24)

Country Link
US (1) US4940716A (es)
EP (1) EP0324184B1 (es)
JP (1) JPH01213266A (es)
CN (1) CN1022917C (es)
AT (1) ATE112268T1 (es)
AU (1) AU635463B2 (es)
CA (1) CA1329209C (es)
CS (1) CS274495B2 (es)
DD (1) DD283382A5 (es)
DE (1) DE3851697D1 (es)
ES (1) ES2059485T3 (es)
FI (1) FI90536C (es)
HR (1) HRP920564A2 (es)
HU (1) HU198458B (es)
IE (1) IE883879L (es)
IL (1) IL88639A (es)
NO (1) NO176177C (es)
NZ (1) NZ227416A (es)
PH (1) PH25608A (es)
PL (1) PL155977B1 (es)
PT (1) PT89356B (es)
SU (2) SU1676444A3 (es)
YU (1) YU46720B (es)
ZA (1) ZA889285B (es)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE102005002130A1 (de) * 2005-01-17 2006-07-27 Sanofi-Aventis Deutschland Gmbh Substituierte N-Aminomethylensulfonamide, ihre Herstellung und Verwendung als Arzneimittel

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3037984A (en) * 1960-01-27 1962-06-05 Lakeside Lab Inc Derivatives of n-amino-1, 2, 3, 4-tetrahydroisoquinoline
JPH01503233A (ja) * 1986-10-28 1989-11-02 スミス・クライン・アンド・フレンチ・ラボラトリース・リミテッド 製薬活性化合物

Also Published As

Publication number Publication date
YU46720B (sh) 1994-04-05
EP0324184A3 (en) 1990-05-02
PT89356A (pt) 1989-12-29
SU1676444A3 (ru) 1991-09-07
PT89356B (pt) 1993-09-30
JPH01213266A (ja) 1989-08-28
FI90536B (fi) 1993-11-15
HRP920564A2 (hr) 1994-04-30
CS902588A2 (en) 1990-09-12
NO885811L (no) 1989-07-03
FI886046A (fi) 1989-07-01
PH25608A (en) 1991-08-08
NO176177C (no) 1995-02-15
DD283382A5 (de) 1990-10-10
AU635463B2 (en) 1993-03-18
IL88639A0 (en) 1989-07-31
PL276887A1 (en) 1989-09-04
IL88639A (en) 1992-11-15
US4940716A (en) 1990-07-10
IE883879L (en) 1989-06-30
EP0324184A2 (de) 1989-07-19
NO176177B (no) 1994-11-07
HU198458B (en) 1989-10-30
NO885811D0 (no) 1988-12-29
AU2762888A (en) 1989-07-06
DE3851697D1 (de) 1994-11-03
CS274495B2 (en) 1991-04-11
ZA889285B (en) 1989-09-27
YU236088A (en) 1990-02-28
ATE112268T1 (de) 1994-10-15
CA1329209C (en) 1994-05-03
FI90536C (fi) 1994-02-25
CN1022917C (zh) 1993-12-01
NZ227416A (en) 1990-11-27
CN1035502A (zh) 1989-09-13
EP0324184B1 (de) 1994-09-28
SU1705287A1 (ru) 1992-01-15
HUT48599A (en) 1989-06-28
PL155977B1 (en) 1992-01-31

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