ES2014593A6 - Un metodo para preparar un vector de acido nucleico que codifica una proteina de cr1. - Google Patents
Un metodo para preparar un vector de acido nucleico que codifica una proteina de cr1.Info
- Publication number
- ES2014593A6 ES2014593A6 ES8901125A ES8901125A ES2014593A6 ES 2014593 A6 ES2014593 A6 ES 2014593A6 ES 8901125 A ES8901125 A ES 8901125A ES 8901125 A ES8901125 A ES 8901125A ES 2014593 A6 ES2014593 A6 ES 2014593A6
- Authority
- ES
- Spain
- Prior art keywords
- fragments
- expression
- protein
- secreted
- proteins
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/2896—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against molecules with a "CD"-designation, not provided for elsewhere
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
- C07K14/315—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Streptococcus (G), e.g. Enterococci
- C07K14/3153—Streptokinase
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
- C07K14/70596—Molecules with a "CD"-designation not provided for elsewhere
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Immunology (AREA)
- Pharmacology & Pharmacy (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Animal Behavior & Ethology (AREA)
- Engineering & Computer Science (AREA)
- General Chemical & Material Sciences (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Heart & Thoracic Surgery (AREA)
- Gastroenterology & Hepatology (AREA)
- Cardiology (AREA)
- Hematology (AREA)
- Diabetes (AREA)
- Transplantation (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Urology & Nephrology (AREA)
- Vascular Medicine (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Cell Biology (AREA)
- Toxicology (AREA)
- Zoology (AREA)
- Peptides Or Proteins (AREA)
- Joining Of Building Structures In Genera (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Abstract
METODO PARA PREPARAR UN VECTOR DE ACIDO NUCLEICO QUE CODIFICA UNA PROTEINA DE CR1. CONSISTE EN INTRODUCIR EN UNA CELULA UN VECTOR DE ACIDO NUCLEICO QUE COMPRENDE LA SECUENCIA DE NUCLEOTIDOS DEL GEN DEL RECEPTOR C3B/C4B (CR1), Y PROPAGAR EL VECTOR DE ACIDO NUCLEICO MEDIANTE PROPAGACION DE LA CELULA, ELIGIENDOSE ESTA PREFERIBLAMENTE ENTRE BACTERIAS Y CELULAS DE MAMIFEROS. EL INVENTO PERMITE OBTENER TAMBIEN SECUENCIAS DE ACIDOS NUCLEICOS DE CR1 Y FRAGMENTOS DE LAS MISMAS QUE CONTIENEN 70 NUCLEOTIDOS, ASI COMO SUS PEPTIDOS O PROTEINAS CODIFICADOS QUE CONTIENEN 24 AMINOACIDOS, PROPORCIONANDOSE ADEMAS LA EXPRESION DE LA PROTEINA DE CR1 Y SUS FRAGMENTOS. LOS PRODUCTOS OBTENIDOS SON UTILES EN DIAGNOSTICOS Y TERAPIA DE DIVERSAS AFECCIONES DEL SISTEMA INMUNE Y ENFERMEDADES INFLAMATORIAS.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US17653288A | 1988-04-01 | 1988-04-01 | |
US41274589A | 1989-09-26 | 1989-09-26 |
Publications (1)
Publication Number | Publication Date |
---|---|
ES2014593A6 true ES2014593A6 (es) | 1990-07-16 |
Family
ID=26872337
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES8901125A Expired - Fee Related ES2014593A6 (es) | 1988-04-01 | 1989-03-31 | Un metodo para preparar un vector de acido nucleico que codifica una proteina de cr1. |
Country Status (14)
Country | Link |
---|---|
EP (1) | EP0411031B1 (es) |
JP (1) | JP3484189B2 (es) |
CN (2) | CN1092712C (es) |
AT (1) | ATE240973T1 (es) |
CA (2) | CA1341443C (es) |
DE (1) | DE68929466T2 (es) |
DK (1) | DK175699B1 (es) |
ES (1) | ES2014593A6 (es) |
FI (2) | FI106316B (es) |
IL (1) | IL89790A (es) |
NO (1) | NO315944B1 (es) |
SG (1) | SG52789A1 (es) |
WO (1) | WO1989009220A1 (es) |
ZA (2) | ZA892397B (es) |
Families Citing this family (31)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5426029A (en) * | 1986-03-31 | 1995-06-20 | T Cell Diagnostics, Inc. | Therapeutic and diagnostic methods using leukocyte surface antigens |
US5256642A (en) * | 1988-04-01 | 1993-10-26 | The Johns Hopkins University | Compositions of soluble complement receptor 1 (CR1) and a thrombolytic agent, and the methods of use thereof |
US6482404B1 (en) | 1989-10-12 | 2002-11-19 | David James White | Transplantation of tissue comprising a DNA sequence encoding a homologous complement restriction factor |
IE75345B1 (en) * | 1989-10-12 | 1997-08-27 | Imutran Ltd | Modified biological material |
US6552170B1 (en) | 1990-04-06 | 2003-04-22 | Amgen Inc. | PEGylation reagents and compounds formed therewith |
US6458360B1 (en) * | 1990-04-25 | 2002-10-01 | The Johns Hopkins University | Soluble complement regulatory molecules |
CA2096418C (en) * | 1990-11-26 | 2001-11-20 | Philip J. Barr | Expression of pace in host cells and methods of use thereof |
AU9149791A (en) * | 1990-12-06 | 1992-07-08 | T Cell Sciences, Inc. | Synergistic compositions of soluble complement receptors and compounds that inhibit complement and/or suppress immune activity |
EP0512733A2 (en) * | 1991-05-03 | 1992-11-11 | Washington University | Modified complement system regulator |
JP3939747B2 (ja) * | 1992-06-24 | 2007-07-04 | アドプロテック・リミテッド | 可溶性cr1誘導体 |
US5456909A (en) * | 1992-08-07 | 1995-10-10 | T Cell Sciences, Inc. | Glycoform fractions of recombinant soluble complement receptor 1 (sCR1) having extended half-lives in vivo |
DE69431290D1 (de) * | 1993-02-12 | 2002-10-10 | Avant Immunotherapeutics Inc | PULMONÄRE VERABREICHUNG DES LÖSLICHEN KOMPLEMENT-RECEPTORS TYP 1 sCR1 |
BR9708387A (pt) | 1996-03-28 | 2000-01-04 | Genitrix Llc | Processo para vacinação de um mamìfero a um antìgeno selecionado, células patogênica e hospedeira, composição de vacina, ácido nucleico, e, opsonina engenheirada. |
TW555765B (en) | 1996-07-09 | 2003-10-01 | Amgen Inc | Low molecular weight soluble tumor necrosis factor type-I and type-II proteins |
GB9706950D0 (en) * | 1997-04-05 | 1997-05-21 | Chernajovsky Yuti | Immune modulation by polypeptides related to CR1 |
AU5317499A (en) * | 1998-07-24 | 2000-02-14 | Uab Research Foundation | Genetic polymorphism in a complement receptor |
US6664052B1 (en) | 1998-07-24 | 2003-12-16 | The Uab Research Foundation | Genetic polymorphism in a complement receptor |
GB9905503D0 (en) | 1999-03-10 | 1999-05-05 | Adprotech Plc | Novel compound formulations and methods of delivery |
EP1738763A1 (en) | 2005-06-30 | 2007-01-03 | AVANT Immunotherapeutics, Inc. | Use of complement inhibitory proteins to treat spinal cord injury |
PT3028716T (pt) | 2006-10-10 | 2020-11-23 | Regenesance B V | Inibição do complemento para regeneração nervosa melhorada |
CN102245765B (zh) | 2008-10-21 | 2015-01-07 | 通用医院公司 | 细胞移植 |
CN103153376B (zh) | 2010-08-06 | 2018-04-20 | 通用医院公司以麻省总医院名义经营 | 用于细胞处理相关应用的系统和设备 |
CA2811291C (en) | 2010-09-15 | 2018-05-29 | Celldex Therapeutics, Inc. | Treatment of chronic nephropathies using soluble complement receptor type i (scr1) |
WO2012058479A2 (en) | 2010-10-27 | 2012-05-03 | Celldex Therapeutics, Inc. | Method of improving transplant function using soluble complement receptor type i (scr1) |
ES2564290T3 (es) | 2010-11-02 | 2016-03-21 | Kypha, Inc. | Inmunoensayo de flujo lateral para la activación de complemento y métodos de uso para evaluación del sitio de atención de trastornos asociados a complemento |
CN102702339B (zh) * | 2011-05-24 | 2013-10-30 | 华南师范大学 | 斜带石斑鱼补体c3基因、载体、重组菌株和蛋白及其应用 |
EP2785744B1 (en) * | 2011-12-01 | 2017-10-04 | AP Biosciences, Inc. | Protein inhibitors to complement and vegf pathways and methods of use thereof |
WO2013082458A1 (en) | 2011-12-02 | 2013-06-06 | The Regents Of The University Of California | Reperfusion protection solution and uses thereof |
CN104293836A (zh) * | 2014-06-24 | 2015-01-21 | 长沙赢润生物技术有限公司 | 一种免疫复合物吸附细胞的制作方法 |
GB201800620D0 (en) | 2018-01-15 | 2018-02-28 | Univ Manchester | C3b Binding Polypeptide |
EP3760645A1 (en) * | 2019-07-02 | 2021-01-06 | imusyn GmbH & Co. KG | Analysis for blood group antigen dacy |
Family Cites Families (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS60192948A (ja) * | 1984-03-14 | 1985-10-01 | Fuji Photo Film Co Ltd | 湿し水不要ネガ型感光性平版印刷版および製版方法 |
US4672044A (en) * | 1984-08-24 | 1987-06-09 | Scripps Clinic & Research Foundation | Murine monoclonal antibody combining site to human C3b receptor (CR1) |
-
1989
- 1989-03-29 IL IL8979089A patent/IL89790A/en active IP Right Grant
- 1989-03-31 ZA ZA892397A patent/ZA892397B/xx unknown
- 1989-03-31 AT AT89905249T patent/ATE240973T1/de not_active IP Right Cessation
- 1989-03-31 CA CA000617127A patent/CA1341443C/en not_active Expired - Fee Related
- 1989-03-31 ES ES8901125A patent/ES2014593A6/es not_active Expired - Fee Related
- 1989-03-31 DE DE68929466T patent/DE68929466T2/de not_active Expired - Fee Related
- 1989-03-31 CA CA000595389A patent/CA1340866C/en not_active Expired - Fee Related
- 1989-03-31 JP JP50500089A patent/JP3484189B2/ja not_active Expired - Fee Related
- 1989-03-31 EP EP89905249A patent/EP0411031B1/en not_active Expired - Lifetime
- 1989-03-31 SG SG1996009545A patent/SG52789A1/en unknown
- 1989-03-31 WO PCT/US1989/001358 patent/WO1989009220A1/en active IP Right Grant
- 1989-04-01 CN CN89101990A patent/CN1092712C/zh not_active Expired - Fee Related
-
1990
- 1990-09-26 ZA ZA907693A patent/ZA907693B/xx unknown
- 1990-09-26 CN CN90108145A patent/CN1053924C/zh not_active Expired - Fee Related
- 1990-09-28 DK DK199002348A patent/DK175699B1/da not_active IP Right Cessation
- 1990-10-01 FI FI904842A patent/FI106316B/fi active IP Right Grant
-
2000
- 2000-02-18 NO NO20000827A patent/NO315944B1/no not_active IP Right Cessation
- 2000-11-16 FI FI20002515A patent/FI115528B/fi active IP Right Grant
Also Published As
Publication number | Publication date |
---|---|
ZA892397B (en) | 1989-11-29 |
IL89790A0 (en) | 1989-09-28 |
FI115528B (fi) | 2005-05-31 |
ATE240973T1 (de) | 2003-06-15 |
AU3539489A (en) | 1989-10-16 |
ZA907693B (en) | 1992-05-27 |
DE68929466D1 (de) | 2003-06-26 |
NO20000827D0 (no) | 2000-02-18 |
AU647371B2 (en) | 1994-03-24 |
EP0411031A1 (en) | 1991-02-06 |
SG52789A1 (en) | 1998-09-28 |
IL89790A (en) | 2002-05-23 |
DK175699B1 (da) | 2005-01-24 |
WO1989009220A1 (en) | 1989-10-05 |
NO20000827L (no) | 1990-11-09 |
EP0411031A4 (en) | 1992-02-05 |
DK234890A (da) | 1990-11-30 |
DK234890D0 (da) | 1990-09-28 |
FI904842A0 (fi) | 1990-10-01 |
CN1053924C (zh) | 2000-06-28 |
CN1053265A (zh) | 1991-07-24 |
CN1036987A (zh) | 1989-11-08 |
FI20002515A (fi) | 2000-11-16 |
JP3484189B2 (ja) | 2004-01-06 |
FI106316B (fi) | 2001-01-15 |
CN1092712C (zh) | 2002-10-16 |
CA1341443C (en) | 2003-10-07 |
NO315944B1 (no) | 2003-11-17 |
CA1340866C (en) | 1999-12-28 |
DE68929466T2 (de) | 2004-04-01 |
JPH04501502A (ja) | 1992-03-19 |
EP0411031B1 (en) | 2003-05-21 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
FD1A | Patent lapsed |
Effective date: 20080401 |