DK234890D0 - Humant c3b/c4b-receptorgen (cr1), nucleinsyresekvenser og fragmenter deraf, deres ekspression samt proteiner og peptider kodet deraf - Google Patents

Humant c3b/c4b-receptorgen (cr1), nucleinsyresekvenser og fragmenter deraf, deres ekspression samt proteiner og peptider kodet deraf

Info

Publication number
DK234890D0
DK234890D0 DK234890A DK234890A DK234890D0 DK 234890 D0 DK234890 D0 DK 234890D0 DK 234890 A DK234890 A DK 234890A DK 234890 A DK234890 A DK 234890A DK 234890 D0 DK234890 D0 DK 234890D0
Authority
DK
Denmark
Prior art keywords
fragments
expression
proteins
receptor
nucleic acid
Prior art date
Application number
DK234890A
Other languages
English (en)
Other versions
DK234890A (da
DK175699B1 (da
Inventor
Douglas T Fearon
Lloyd B Klickstein
Winnie W Wong
Gerald R Carson
Michael F Concino
Stephen H Ip
Savvas C Makrides
Jr Henry C Marsh
Original Assignee
Univ Johns Hopkins
Brigham & Womens Hospital
T Cell Sciences Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Johns Hopkins, Brigham & Womens Hospital, T Cell Sciences Inc filed Critical Univ Johns Hopkins
Publication of DK234890D0 publication Critical patent/DK234890D0/da
Publication of DK234890A publication Critical patent/DK234890A/da
Application granted granted Critical
Publication of DK175699B1 publication Critical patent/DK175699B1/da

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2896—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against molecules with a "CD"-designation, not provided for elsewhere
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/315—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Streptococcus (G), e.g. Enterococci
    • C07K14/3153—Streptokinase
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/70596—Molecules with a "CD"-designation not provided for elsewhere
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Immunology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Oncology (AREA)
  • Transplantation (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Communicable Diseases (AREA)
  • Vascular Medicine (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • Cell Biology (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Peptides Or Proteins (AREA)
  • Joining Of Building Structures In Genera (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
DK199002348A 1988-04-01 1990-09-28 Nucleinsyremolekyle, rekombinant DNA-vektor indeholdende nucleinsyremolekylet, rekombinant ekspressionsvektor indeholdende nucleinsyremolekylet, celle indeholdende nucleotidsekvensen, oplöseligt CR1-polypeptid, fremgangsmåde til fremstilling ............. DK175699B1 (da)

Applications Claiming Priority (6)

Application Number Priority Date Filing Date Title
US17653288A 1988-04-01 1988-04-01
US17653288 1988-04-01
PCT/US1989/001358 WO1989009220A1 (en) 1988-04-01 1989-03-31 THE HUMAN C3b/C4b RECEPTOR (CR1)
US8901358 1989-03-31
US41274589A 1989-09-26 1989-09-26
US41274589 1989-09-26

Publications (3)

Publication Number Publication Date
DK234890D0 true DK234890D0 (da) 1990-09-28
DK234890A DK234890A (da) 1990-11-30
DK175699B1 DK175699B1 (da) 2005-01-24

Family

ID=26872337

Family Applications (1)

Application Number Title Priority Date Filing Date
DK199002348A DK175699B1 (da) 1988-04-01 1990-09-28 Nucleinsyremolekyle, rekombinant DNA-vektor indeholdende nucleinsyremolekylet, rekombinant ekspressionsvektor indeholdende nucleinsyremolekylet, celle indeholdende nucleotidsekvensen, oplöseligt CR1-polypeptid, fremgangsmåde til fremstilling .............

Country Status (14)

Country Link
EP (1) EP0411031B1 (da)
JP (1) JP3484189B2 (da)
CN (2) CN1092712C (da)
AT (1) ATE240973T1 (da)
CA (2) CA1341443C (da)
DE (1) DE68929466T2 (da)
DK (1) DK175699B1 (da)
ES (1) ES2014593A6 (da)
FI (2) FI106316B (da)
IL (1) IL89790A (da)
NO (1) NO315944B1 (da)
SG (1) SG52789A1 (da)
WO (1) WO1989009220A1 (da)
ZA (2) ZA892397B (da)

Families Citing this family (31)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5426029A (en) * 1986-03-31 1995-06-20 T Cell Diagnostics, Inc. Therapeutic and diagnostic methods using leukocyte surface antigens
US5256642A (en) * 1988-04-01 1993-10-26 The Johns Hopkins University Compositions of soluble complement receptor 1 (CR1) and a thrombolytic agent, and the methods of use thereof
HUT64584A (en) * 1989-10-12 1994-01-28 Imutran Ltd Modified biological material
US6482404B1 (en) 1989-10-12 2002-11-19 David James White Transplantation of tissue comprising a DNA sequence encoding a homologous complement restriction factor
US6552170B1 (en) 1990-04-06 2003-04-22 Amgen Inc. PEGylation reagents and compounds formed therewith
US6458360B1 (en) * 1990-04-25 2002-10-01 The Johns Hopkins University Soluble complement regulatory molecules
EP0785273A1 (en) * 1990-11-26 1997-07-23 Genetics Institute, Inc. Paired basic amino acid converting enzyme and DNA sequence encoding it
JPH06503344A (ja) * 1990-12-06 1994-04-14 ティーセル　サイエンシズ，インコーポレーテッド 可溶性の補体受容体と、補体を抑制しかつ／または免疫活性を抑制する化合物との相乗組成物
EP0512733A2 (en) * 1991-05-03 1992-11-11 Washington University Modified complement system regulator
WO1994000571A1 (en) * 1992-06-24 1994-01-06 Smithkline Beecham Plc Soluble cr1 derivatives
US5456909A (en) * 1992-08-07 1995-10-10 T Cell Sciences, Inc. Glycoform fractions of recombinant soluble complement receptor 1 (sCR1) having extended half-lives in vivo
JP3689422B2 (ja) 1993-02-12 2005-08-31 アーヴァント イミュノセラピューティクス インコーポレイテッド ｓＣＲ１およびその他の補体阻害蛋白の肺内投与
WO1997035619A1 (en) 1996-03-28 1997-10-02 Genitrix, L.L.C. Opsonin-enhanced cells, and methods of modulating an immune response to an antigen
TW555765B (en) 1996-07-09 2003-10-01 Amgen Inc Low molecular weight soluble tumor necrosis factor type-I and type-II proteins
GB9706950D0 (en) * 1997-04-05 1997-05-21 Chernajovsky Yuti Immune modulation by polypeptides related to CR1
WO2000005413A1 (en) * 1998-07-24 2000-02-03 Uab Research Foundation Genetic polymorphism in a complement receptor
US6664052B1 (en) 1998-07-24 2003-12-16 The Uab Research Foundation Genetic polymorphism in a complement receptor
GB9905503D0 (en) 1999-03-10 1999-05-05 Adprotech Plc Novel compound formulations and methods of delivery
EP1738763A1 (en) 2005-06-30 2007-01-03 AVANT Immunotherapeutics, Inc. Use of complement inhibitory proteins to treat spinal cord injury
LT3028716T (lt) 2006-10-10 2020-12-10 Regenesance B.V. Komplemento slopinimas nervų regeneracijos pagerinimui
AU2009308152B2 (en) 2008-10-21 2015-05-21 The General Hospital Corporation Cell transplantation
US10184110B2 (en) 2010-08-06 2019-01-22 The General Hospital Corporation System and apparatus for cell treatment
CN107661491A (zh) 2010-09-15 2018-02-06 赛尔戴克斯治疗公司 用可溶性I型补体受体(sCR1)治疗慢性肾病
WO2012058479A2 (en) 2010-10-27 2012-05-03 Celldex Therapeutics, Inc. Method of improving transplant function using soluble complement receptor type i (scr1)
AU2011332241B2 (en) 2010-11-02 2015-11-26 Kypha, Inc. Lateral flow immunoassay for complement activation and methods of use for point-of-care assessment of complement-associated disorders
CN102702339B (zh) * 2011-05-24 2013-10-30 华南师范大学 斜带石斑鱼补体c3基因、载体、重组菌株和蛋白及其应用
EP2785744B1 (en) * 2011-12-01 2017-10-04 AP Biosciences, Inc. Protein inhibitors to complement and vegf pathways and methods of use thereof
WO2013082458A1 (en) 2011-12-02 2013-06-06 The Regents Of The University Of California Reperfusion protection solution and uses thereof
CN104293836A (zh) * 2014-06-24 2015-01-21 长沙赢润生物技术有限公司 一种免疫复合物吸附细胞的制作方法
GB201800620D0 (en) 2018-01-15 2018-02-28 Univ Manchester C3b Binding Polypeptide
EP3760645A1 (en) * 2019-07-02 2021-01-06 imusyn GmbH & Co. KG Analysis for blood group antigen dacy

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS60192948A (ja) * 1984-03-14 1985-10-01 Fuji Photo Film Co Ltd 湿し水不要ネガ型感光性平版印刷版および製版方法
US4672044A (en) * 1984-08-24 1987-06-09 Scripps Clinic & Research Foundation Murine monoclonal antibody combining site to human C3b receptor (CR1)

Also Published As

Publication number Publication date
CN1036987A (zh) 1989-11-08
FI106316B (fi) 2001-01-15
DK234890A (da) 1990-11-30
CN1053265A (zh) 1991-07-24
FI20002515A (fi) 2000-11-16
ES2014593A6 (es) 1990-07-16
CA1340866C (en) 1999-12-28
CN1092712C (zh) 2002-10-16
JPH04501502A (ja) 1992-03-19
DE68929466D1 (de) 2003-06-26
FI115528B (fi) 2005-05-31
NO20000827L (no) 1990-11-09
DE68929466T2 (de) 2004-04-01
FI904842A0 (fi) 1990-10-01
EP0411031A4 (en) 1992-02-05
SG52789A1 (en) 1998-09-28
ATE240973T1 (de) 2003-06-15
JP3484189B2 (ja) 2004-01-06
ZA892397B (en) 1989-11-29
EP0411031A1 (en) 1991-02-06
IL89790A (en) 2002-05-23
NO20000827D0 (no) 2000-02-18
EP0411031B1 (en) 2003-05-21
CN1053924C (zh) 2000-06-28
WO1989009220A1 (en) 1989-10-05
AU647371B2 (en) 1994-03-24
IL89790A0 (en) 1989-09-28
NO315944B1 (no) 2003-11-17
DK175699B1 (da) 2005-01-24
CA1341443C (en) 2003-10-07
AU3539489A (en) 1989-10-16
ZA907693B (en) 1992-05-27

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