EP1589934A4 - Bestimmte aminoalkyl-glucosaminid-phosphatverbindungen und ihre verwendung - Google Patents

Bestimmte aminoalkyl-glucosaminid-phosphatverbindungen und ihre verwendung

Info

Publication number
EP1589934A4
EP1589934A4 EP04700403A EP04700403A EP1589934A4 EP 1589934 A4 EP1589934 A4 EP 1589934A4 EP 04700403 A EP04700403 A EP 04700403A EP 04700403 A EP04700403 A EP 04700403A EP 1589934 A4 EP1589934 A4 EP 1589934A4
Authority
EP
European Patent Office
Prior art keywords
phosphate compounds
aminoalkyl glucosaminide
glucosaminide phosphate
certain aminoalkyl
certain
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
EP04700403A
Other languages
English (en)
French (fr)
Other versions
EP1589934B1 (de
EP1589934A2 (de
Inventor
David A Johnson
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Corixa Corp
Original Assignee
Corixa Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Corixa Corp filed Critical Corixa Corp
Priority to EP15161799.0A priority Critical patent/EP2940028B8/de
Priority to SI200432284T priority patent/SI1589934T1/sl
Publication of EP1589934A2 publication Critical patent/EP1589934A2/de
Publication of EP1589934A4 publication Critical patent/EP1589934A4/de
Application granted granted Critical
Publication of EP1589934B1 publication Critical patent/EP1589934B1/de
Priority to CY20151101158T priority patent/CY1117129T1/el
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H13/00Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids
    • C07H13/02Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids by carboxylic acids
    • C07H13/04Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids by carboxylic acids having the esterifying carboxyl radicals attached to acyclic carbon atoms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • A61P37/04Immunostimulants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • A61P37/06Immunosuppressants, e.g. drugs for graft rejection
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/08Antiallergic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H11/00Compounds containing saccharide radicals esterified by inorganic acids; Metal salts thereof
    • C07H11/04Phosphates; Phosphites; Polyphosphates
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/02Acyclic radicals, not substituted by cyclic structures
    • C07H15/04Acyclic radicals, not substituted by cyclic structures attached to an oxygen atom of the saccharide radical
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H5/00Compounds containing saccharide radicals in which the hetero bonds to oxygen have been replaced by the same number of hetero bonds to halogen, nitrogen, sulfur, selenium, or tellurium
    • C07H5/02Compounds containing saccharide radicals in which the hetero bonds to oxygen have been replaced by the same number of hetero bonds to halogen, nitrogen, sulfur, selenium, or tellurium to halogen
EP04700403.1A 2003-01-06 2004-01-06 Bestimmte aminoalkyl-glucosaminid-phosphatverbindungen und ihre verwendung Expired - Lifetime EP1589934B1 (de)

Priority Applications (3)

Application Number Priority Date Filing Date Title
EP15161799.0A EP2940028B8 (de) 2003-01-06 2004-01-06 Bestimmte aminoalkyl-glucosaminid-phosphatverbindungen und ihre verwendung
SI200432284T SI1589934T1 (sl) 2003-01-06 2004-01-06 Določene aminoalkil glukozaminid fosfat spojine in njih uporaba
CY20151101158T CY1117129T1 (el) 2003-01-06 2015-12-17 Συγκεκριμενες φωσφορικες ενωσεις αμυναλκιλικου γλυκοζαμινιδιου και η χρηση τους

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US43858503P 2003-01-06 2003-01-06
US438585P 2003-01-06
PCT/US2004/000377 WO2004062599A2 (en) 2003-01-06 2004-01-06 Certain aminoalkyl glucosaminide phosphate compounds and their use

Related Child Applications (2)

Application Number Title Priority Date Filing Date
EP15161799.0A Division-Into EP2940028B8 (de) 2003-01-06 2004-01-06 Bestimmte aminoalkyl-glucosaminid-phosphatverbindungen und ihre verwendung
EP15161799.0A Division EP2940028B8 (de) 2003-01-06 2004-01-06 Bestimmte aminoalkyl-glucosaminid-phosphatverbindungen und ihre verwendung

Publications (3)

Publication Number Publication Date
EP1589934A2 EP1589934A2 (de) 2005-11-02
EP1589934A4 true EP1589934A4 (de) 2011-09-07
EP1589934B1 EP1589934B1 (de) 2015-09-23

Family

ID=32713348

Family Applications (2)

Application Number Title Priority Date Filing Date
EP15161799.0A Expired - Lifetime EP2940028B8 (de) 2003-01-06 2004-01-06 Bestimmte aminoalkyl-glucosaminid-phosphatverbindungen und ihre verwendung
EP04700403.1A Expired - Lifetime EP1589934B1 (de) 2003-01-06 2004-01-06 Bestimmte aminoalkyl-glucosaminid-phosphatverbindungen und ihre verwendung

Family Applications Before (1)

Application Number Title Priority Date Filing Date
EP15161799.0A Expired - Lifetime EP2940028B8 (de) 2003-01-06 2004-01-06 Bestimmte aminoalkyl-glucosaminid-phosphatverbindungen und ihre verwendung

Country Status (20)

Country Link
EP (2) EP2940028B8 (de)
JP (2) JP4838706B2 (de)
KR (2) KR20110120989A (de)
CN (2) CN101863930A (de)
AU (1) AU2004204754B2 (de)
BR (1) BRPI0406628A (de)
CA (1) CA2512108C (de)
CY (1) CY1117129T1 (de)
DK (1) DK1589934T3 (de)
ES (2) ES2639812T3 (de)
HK (2) HK1217104A1 (de)
HU (1) HUE026376T2 (de)
IL (1) IL169540A (de)
MX (1) MXPA05007295A (de)
PL (1) PL220536B1 (de)
PT (1) PT1589934E (de)
RU (3) RU2544850C2 (de)
SI (1) SI1589934T1 (de)
WO (1) WO2004062599A2 (de)
ZA (1) ZA200505302B (de)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7960522B2 (en) 2003-01-06 2011-06-14 Corixa Corporation Certain aminoalkyl glucosaminide phosphate compounds and their use
CA2512108C (en) * 2003-01-06 2013-04-02 Corixa Corporation Certain aminoalkyl glucosaminide phosphate compounds and their use
EP1853227B1 (de) * 2005-03-02 2009-08-05 The Secretary of State for Defence Pharmazeutische zusammensetzung
GB201009273D0 (en) * 2010-06-03 2010-07-21 Glaxosmithkline Biolog Sa Novel vaccine
GB201101331D0 (en) 2011-01-26 2011-03-09 Glaxosmithkline Biolog Sa Compositions and uses
GB201113570D0 (en) 2011-08-05 2011-09-21 Glaxosmithkline Biolog Sa Vaccine
BE1021939B1 (fr) 2013-03-15 2016-01-27 Glaxosmithkline Biologicals S.A. Composition pour des composes aminoalkylglucosaminide phosphate tamponnes et son utilisation.
PL3116887T3 (pl) 2014-03-13 2021-09-06 Universität Basel Ligandy węglowodanowe, które wiążą się z przeciwciałami igm przeciwko glikoproteinie związanej z mieliną
JP2018509384A (ja) * 2015-01-06 2018-04-05 イミューノヴァクシーン テクノロジーズ インコーポレイテッドImmunovaccine Technologies Inc. リピドa模倣体、調製方法、及びその使用
CN108026134A (zh) * 2015-09-16 2018-05-11 巴塞尔大学 结合抗糖鞘脂糖蛋白表位抗体的碳水化合物配体
GB201616904D0 (en) 2016-10-05 2016-11-16 Glaxosmithkline Biologicals Sa Vaccine
EP3886901A1 (de) 2018-11-29 2021-10-06 GlaxoSmithKline Biologicals S.A. Verfahren zur herstellung eines adjuvans
BR112022000710A2 (pt) 2019-07-21 2022-03-22 Glaxosmithkline Biologicals Sa Vacina viral terapêutica
US20230234992A1 (en) 2020-06-05 2023-07-27 Glaxosmithkline Biologicals Sa Modified betacoronavirus spike proteins
BR112022025969A2 (pt) 2020-06-22 2023-01-17 Sumitomo Pharma Co Ltd Adjuvante com atividade agonista de tlr4
EP4032547A1 (de) 2021-01-20 2022-07-27 GlaxoSmithKline Biologicals S.A. Hsv1 fce abgeleitete fragemente zur hsv therapie

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2001034617A2 (en) * 1999-11-12 2001-05-17 Corixa Corporation Aminoalkyl glucosaminide phosphate compounds and their use as adjuvants and immunoeffectors

Family Cites Families (94)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4603112A (en) 1981-12-24 1986-07-29 Health Research, Incorporated Modified vaccinia virus
US4769330A (en) 1981-12-24 1988-09-06 Health Research, Incorporated Modified vaccinia virus and methods for making and using the same
US4866034A (en) 1982-05-26 1989-09-12 Ribi Immunochem Research Inc. Refined detoxified endotoxin
US4436727A (en) 1982-05-26 1984-03-13 Ribi Immunochem Research, Inc. Refined detoxified endotoxin product
US4987237A (en) 1983-08-26 1991-01-22 Ribi Immunochem Research, Inc. Derivatives of monophosphoryl lipid A
US5128326A (en) 1984-12-06 1992-07-07 Biomatrix, Inc. Drug delivery systems based on hyaluronans derivatives thereof and their salts and methods of producing same
US4883750A (en) 1984-12-13 1989-11-28 Applied Biosystems, Inc. Detection of specific sequences in nucleic acids
US4751180A (en) 1985-03-28 1988-06-14 Chiron Corporation Expression using fused genes providing for protein product
US4683202A (en) 1985-03-28 1987-07-28 Cetus Corporation Process for amplifying nucleic acid sequences
US4683195A (en) 1986-01-30 1987-07-28 Cetus Corporation Process for amplifying, detecting, and/or-cloning nucleic acid sequences
GB8508845D0 (en) 1985-04-04 1985-05-09 Hoffmann La Roche Vaccinia dna
US4777127A (en) 1985-09-30 1988-10-11 Labsystems Oy Human retrovirus-related products and methods of diagnosing and treating conditions associated with said retrovirus
US5139941A (en) 1985-10-31 1992-08-18 University Of Florida Research Foundation, Inc. AAV transduction vectors
US4935233A (en) 1985-12-02 1990-06-19 G. D. Searle And Company Covalently linked polypeptide cell modulators
US4800159A (en) 1986-02-07 1989-01-24 Cetus Corporation Process for amplifying, detecting, and/or cloning nucleic acid sequences
US4877611A (en) 1986-04-15 1989-10-31 Ribi Immunochem Research Inc. Vaccine containing tumor antigens and adjuvants
GB8702816D0 (en) 1987-02-07 1987-03-11 Al Sumidaie A M K Obtaining retrovirus-containing fraction
US5219740A (en) 1987-02-13 1993-06-15 Fred Hutchinson Cancer Research Center Retroviral gene transfer into diploid fibroblasts for gene therapy
AU622104B2 (en) 1987-03-11 1992-04-02 Sangtec Molecular Diagnostics Ab Method of assaying of nucleic acids, a reagent combination and kit therefore
US4790824A (en) 1987-06-19 1988-12-13 Bioject, Inc. Non-invasive hypodermic injection device
IL86724A (en) 1987-06-19 1995-01-24 Siska Diagnostics Inc Methods and kits for amplification and testing of nucleic acid sequences
DE10399031I1 (de) 1987-08-28 2004-01-29 Health Research Inc Rekombinante Viren.
WO1989001973A2 (en) 1987-09-02 1989-03-09 Applied Biotechnology, Inc. Recombinant pox virus for immunization against tumor-associated antigens
CA1323293C (en) 1987-12-11 1993-10-19 Keith C. Backman Assay using template-dependent nucleic acid probe reorganization
JPH01180896A (ja) * 1988-01-08 1989-07-18 Toho Yakuhin Kogyo Kk 新規ホスホリルグルコサミン誘導体
EP0359789B1 (de) 1988-01-21 1993-08-04 Genentech, Inc. Verstärkung und nachweis von nukleinsäuresequenzen
CA1340807C (en) 1988-02-24 1999-11-02 Lawrence T. Malek Nucleic acid amplification process
AP129A (en) 1988-06-03 1991-04-17 Smithkline Biologicals S A Expression of retrovirus gag protein eukaryotic cells
US4912094B1 (en) 1988-06-29 1994-02-15 Ribi Immunochem Research Inc. Modified lipopolysaccharides and process of preparation
US5549910A (en) 1989-03-31 1996-08-27 The Regents Of The University Of California Preparation of liposome and lipid complex compositions
US5597573A (en) * 1989-05-04 1997-01-28 Igen, Inc. Lipid-A analogs: new monosaccharide and disaccharide intermediates for eliciting therapeutic antibodies and for antitumor and antiviral activities
US5725871A (en) 1989-08-18 1998-03-10 Danbiosyst Uk Limited Drug delivery compositions comprising lysophosphoglycerolipid
EP1001032A3 (de) 1989-08-18 2005-02-23 Chiron Corporation Rekombinante Retroviren um Vektorkonstruktionen an Zielzellen zu liefern
KR920007887B1 (ko) 1989-08-29 1992-09-18 스즈키 지도오샤 고오교오 가부시키가이샤 내연기관의 배기가스 정화장치
US5707644A (en) 1989-11-04 1998-01-13 Danbiosyst Uk Limited Small particle compositions for intranasal drug delivery
JP2571874B2 (ja) 1989-11-06 1997-01-16 アルカーメス コントロールド セラピューティクス,インコーポレイテッド タンパク質マイクロスフェア組成物
US5064413A (en) 1989-11-09 1991-11-12 Bioject, Inc. Needleless hypodermic injection device
US5312335A (en) 1989-11-09 1994-05-17 Bioject Inc. Needleless hypodermic injection device
DK0500799T3 (da) 1989-11-16 1998-09-14 Univ Duke Partikel-medieret transformation af animalske vævsceller
FR2658432B1 (fr) 1990-02-22 1994-07-01 Medgenix Group Sa Microspheres pour la liberation controlee des substances hydrosolubles et procede de preparation.
US5466468A (en) 1990-04-03 1995-11-14 Ciba-Geigy Corporation Parenterally administrable liposome formulation comprising synthetic lipids
SE466259B (sv) 1990-05-31 1992-01-20 Arne Forsgren Protein d - ett igd-bindande protein fraan haemophilus influenzae, samt anvaendning av detta foer analys, vacciner och uppreningsaendamaal
AU8200191A (en) 1990-07-09 1992-02-04 United States of America, as represented by the Secretary, U.S. Department of Commerce, The High efficiency packaging of mutant adeno-associated virus using amber suppressions
JP3218637B2 (ja) 1990-07-26 2001-10-15 大正製薬株式会社 安定なリポソーム水懸濁液
MY109299A (en) 1990-08-15 1996-12-31 Virogenetics Corp Recombinant pox virus encoding flaviviral structural proteins
JP2958076B2 (ja) 1990-08-27 1999-10-06 株式会社ビタミン研究所 遺伝子導入用多重膜リポソーム及び遺伝子捕捉多重膜リポソーム製剤並びにその製法
US5173414A (en) 1990-10-30 1992-12-22 Applied Immune Sciences, Inc. Production of recombinant adeno-associated virus vectors
US5399363A (en) 1991-01-25 1995-03-21 Eastman Kodak Company Surface modified anticancer nanoparticles
US5145684A (en) 1991-01-25 1992-09-08 Sterling Drug Inc. Surface modified drug nanoparticles
WO1993003769A1 (en) 1991-08-20 1993-03-04 THE UNITED STATES OF AMERICA, represented by THE SECRETARY, DEPARTEMENT OF HEALTH AND HUMAN SERVICES Adenovirus mediated transfer of genes to the gastrointestinal tract
US5593969A (en) * 1991-09-03 1997-01-14 Igen Incorporated Lipid-A analogs: monosaccharide and dissaccharide compounds for inhibiting binding of lipid A receptors to lipid A receptors
US5530113A (en) 1991-10-11 1996-06-25 Eisai Co., Ltd. Anti-endotoxin compounds
US5756353A (en) 1991-12-17 1998-05-26 The Regents Of The University Of California Expression of cloned genes in the lung by aerosol-and liposome-based delivery
US5912015A (en) 1992-03-12 1999-06-15 Alkermes Controlled Therapeutics, Inc. Modulated release from biocompatible polymers
EP0641192B1 (de) 1992-05-18 1997-07-23 Minnesota Mining And Manufacturing Company Einrichtung zur transmucosalen wirkstoffabgabe
US5792451A (en) 1994-03-02 1998-08-11 Emisphere Technologies, Inc. Oral drug delivery compositions and methods
US5383851A (en) 1992-07-24 1995-01-24 Bioject Inc. Needleless hypodermic injection device
US5633234A (en) 1993-01-22 1997-05-27 The Johns Hopkins University Lysosomal targeting of immunogens
US5654186A (en) 1993-02-26 1997-08-05 The Picower Institute For Medical Research Blood-borne mesenchymal cells
FR2702160B1 (fr) 1993-03-02 1995-06-02 Biovecteurs As Vecteurs particulaires synthétiques et procédé de préparation.
FR2704145B1 (fr) 1993-04-21 1995-07-21 Pasteur Institut Vecteur particulaire et composition pharmaceutique le contenant.
US5543158A (en) 1993-07-23 1996-08-06 Massachusetts Institute Of Technology Biodegradable injectable nanoparticles
US6015686A (en) 1993-09-15 2000-01-18 Chiron Viagene, Inc. Eukaryotic layered vector initiation systems
CA2158733C (en) 1994-01-21 2007-01-16 Dennis E. Mccabe Gas driven gene delivery instrument
US5505947A (en) 1994-05-27 1996-04-09 The University Of North Carolina At Chapel Hill Attenuating mutations in Venezuelan Equine Encephalitis virus
PT772619E (pt) 1994-07-15 2006-10-31 Univ Iowa Res Found Oligonucleotidos imunomoduladores
FR2723849B1 (fr) 1994-08-31 1997-04-11 Biovector Therapeutics Sa Procede pour augmenter l'immunogenicite, produit obtenu et composition pharmaceutique
US5795587A (en) 1995-01-23 1998-08-18 University Of Pittsburgh Stable lipid-comprising drug delivery complexes and methods for their production
GB9502879D0 (en) 1995-02-14 1995-04-05 Oxford Biosciences Ltd Particle delivery
US5580579A (en) 1995-02-15 1996-12-03 Nano Systems L.L.C. Site-specific adhesion within the GI tract using nanoparticles stabilized by high molecular weight, linear poly (ethylene oxide) polymers
IE80468B1 (en) 1995-04-04 1998-07-29 Elan Corp Plc Controlled release biodegradable nanoparticles containing insulin
EP0832282A1 (de) 1995-06-02 1998-04-01 Incyte Pharmaceuticals, Inc. VERBESSERTER VERFAHREN ZUR HERSTELLUNG VON cDNA-SEQUENZEN MIT VOLLER LÄNGER
US5750664A (en) * 1995-06-05 1998-05-12 Eisai Co., Ltd. Substituted liposaccharides useful in the treatment and prevention of endotoxemia
US5738868A (en) 1995-07-18 1998-04-14 Lipogenics Ltd. Liposome compositions and kits therefor
WO1997007788A2 (en) 1995-08-31 1997-03-06 Alkermes Controlled Therapeutics, Inc. Composition for sustained release of an agent
US5856462A (en) 1996-09-10 1999-01-05 Hybridon Incorporated Oligonucleotides having modified CpG dinucleosides
US5811407A (en) 1997-02-19 1998-09-22 The University Of North Carolina At Chapel Hill System for the in vivo delivery and expression of heterologous genes in the bone marrow
US6355257B1 (en) * 1997-05-08 2002-03-12 Corixa Corporation Aminoalkyl glucosamine phosphate compounds and their use as adjuvants and immunoeffectors
US6113918A (en) * 1997-05-08 2000-09-05 Ribi Immunochem Research, Inc. Aminoalkyl glucosamine phosphate compounds and their use as adjuvants and immunoeffectors
US5993412A (en) 1997-05-19 1999-11-30 Bioject, Inc. Injection apparatus
KR100241901B1 (ko) 1997-08-28 2000-02-01 윤종용 핸드셋과 핸즈프리킷 공용 음성인식기의 등록 엔트리 관리방법
US5989463A (en) 1997-09-24 1999-11-23 Alkermes Controlled Therapeutics, Inc. Methods for fabricating polymer-based controlled release devices
SE512663C2 (sv) 1997-10-23 2000-04-17 Biogram Ab Inkapslingsförfarande för aktiv substans i en bionedbrytbar polymer
GB9727262D0 (en) 1997-12-24 1998-02-25 Smithkline Beecham Biolog Vaccine
AU746163B2 (en) 1998-04-09 2002-04-18 Smithkline Beecham Biologicals (Sa) Adjuvant compositions
US6355251B1 (en) 1999-06-15 2002-03-12 Mark Zamoyski Compositions and methods for epidermal chemexfoliation
WO2001032667A1 (fr) * 1999-11-04 2001-05-10 Sankyo Company, Limited Analogues de gla-60 du type de l'ether
CA2396744C (en) * 1999-11-15 2011-07-12 Biomira, Inc. Synthetic lipid-a analogs and uses thereof
EP1284740B1 (de) 2000-05-19 2008-05-21 Corixa Corporation Prophylaktische und therapeutische behandlung von infektiösen, autoimmunen und allergischen krankheiten mit verbindungen, die auf monosacchariden basieren
ES2261453T3 (es) 2000-08-04 2006-11-16 Corixa Corporation Nuevos compuestos inmunoefectores.
MXPA05000407A (es) * 2002-07-08 2005-04-19 Corixa Corp Procedimientos para la produccion de fosfato de aminoalquilglucosaminida e inmunoefectores de disacarido, e intermediarios para los mismos.
CA2512108C (en) * 2003-01-06 2013-04-02 Corixa Corporation Certain aminoalkyl glucosaminide phosphate compounds and their use
US8312249B1 (en) 2008-10-10 2012-11-13 Apple Inc. Dynamic trampoline and structured code generation in a signed code environment
FR2957821B1 (fr) 2010-03-24 2014-08-29 Inst Francais Du Petrole Nouvelle zone de regeneration du catalyseur divisee en secteurs pour unites catalytiques regeneratives

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2001034617A2 (en) * 1999-11-12 2001-05-17 Corixa Corporation Aminoalkyl glucosaminide phosphate compounds and their use as adjuvants and immunoeffectors

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
PERSING, DAVID H. ET AL: "Taking toll: lipid A mimetics as adjuvants and immunomodulators", TRENDS IN MICROBIOLOGY , 10(10, SUPPL.), S32-S37 CODEN: TRMIEA; ISSN: 0966-842X, 2002, XP009067296 *
See also references of WO2004062599A2 *

Also Published As

Publication number Publication date
JP2007524570A (ja) 2007-08-30
CY1117129T1 (el) 2017-04-05
HK1217104A1 (zh) 2016-12-23
IL169540A0 (en) 2007-07-04
EP1589934B1 (de) 2015-09-23
RU2015104031A (ru) 2016-08-27
RU2005125050A (ru) 2006-01-27
CN101863930A (zh) 2010-10-20
PL220536B1 (pl) 2015-11-30
PT1589934E (pt) 2016-01-26
BRPI0406628A (pt) 2005-12-06
ES2639812T3 (es) 2017-10-30
JP2011246481A (ja) 2011-12-08
ZA200505302B (en) 2007-03-28
KR20110120989A (ko) 2011-11-04
EP1589934A2 (de) 2005-11-02
DK1589934T3 (en) 2015-12-21
CA2512108C (en) 2013-04-02
AU2004204754B2 (en) 2010-04-01
SI1589934T1 (sl) 2016-02-29
AU2004204754A1 (en) 2004-07-29
KR20050090441A (ko) 2005-09-13
RU2389732C2 (ru) 2010-05-20
CA2512108A1 (en) 2004-07-29
RU2544850C2 (ru) 2015-03-20
WO2004062599A3 (en) 2007-01-04
ES2556970T3 (es) 2016-01-21
KR101110889B1 (ko) 2012-02-20
EP2940028A1 (de) 2015-11-04
PL380950A1 (pl) 2007-04-02
CN101080234A (zh) 2007-11-28
JP4838706B2 (ja) 2011-12-14
EP2940028B8 (de) 2017-09-27
MXPA05007295A (es) 2005-09-30
RU2009140730A (ru) 2011-05-10
HK1083593A1 (en) 2006-07-07
IL169540A (en) 2011-04-28
HUE026376T2 (en) 2016-05-30
EP2940028B1 (de) 2017-08-16
WO2004062599A2 (en) 2004-07-29

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